Homo sapiens

18 known processes

EIF3L

eukaryotic translation initiation factor 3, subunit L

(Aliases: HSPC021,HSPC025,MSTP005,EIF3S11,EIF3EIP,EIF3S6IP)

EIF3L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.964
translation GO:0006412 132 0.949
translational initiation GO:0006413 48 0.940
cytoplasmic translational initiation GO:0002183 6 0.912
female gamete generation GO:0007292 2 0.884
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.781
multicellular organismal aging GO:0010259 3 0.727
mitotic spindle elongation GO:0000022 4 0.645
oogenesis GO:0048477 2 0.594
vesicle mediated transport GO:0016192 371 0.548
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.469
positive regulation of peptidase activity GO:0010952 88 0.421
formation of translation preinitiation complex GO:0001731 4 0.418
cell development GO:0048468 328 0.395
Fly
purine nucleoside catabolic process GO:0006152 398 0.298
activation of cysteine type endopeptidase activity GO:0097202 57 0.270
embryo development GO:0009790 123 0.239
protein processing GO:0016485 226 0.210
ribonucleoprotein complex subunit organization GO:0071826 81 0.187
regulation of endopeptidase activity GO:0052548 170 0.186
purine ribonucleotide catabolic process GO:0009154 404 0.172
oxidation reduction process GO:0055114 396 0.165
regulation of apoptotic signaling pathway GO:2001233 175 0.160
cellular component morphogenesis GO:0032989 314 0.149
Fly
positive regulation of proteolysis GO:0045862 142 0.146
rna processing GO:0006396 255 0.135
maturation of ssu rrna GO:0030490 3 0.131
endomembrane system organization GO:0010256 196 0.129
mitotic cell cycle GO:0000278 326 0.125
regulation of proteolysis GO:0030162 293 0.124
receptor mediated endocytosis GO:0006898 84 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.119
positive regulation of apoptotic process GO:0043065 246 0.113
determination of adult lifespan GO:0008340 2 0.111
neuron projection development GO:0031175 106 0.110
Fly
positive regulation of gastrulation GO:2000543 2 0.103
sex differentiation GO:0007548 45 0.103
nucleotide catabolic process GO:0009166 408 0.101
cellular ketone metabolic process GO:0042180 80 0.096
endocytosis GO:0006897 159 0.095
reproductive system development GO:0061458 56 0.088
multi organism reproductive process GO:0044703 54 0.086
reproduction GO:0000003 63 0.084
embryo development ending in birth or egg hatching GO:0009792 34 0.078
cell part morphogenesis GO:0032990 137 0.077
Fly
rrna metabolic process GO:0016072 40 0.076
cell morphogenesis GO:0000902 296 0.075
Fly
cardiovascular system development GO:0072358 262 0.074
golgi organization GO:0007030 38 0.074
cell projection organization GO:0030030 252 0.074
Fly
microtubule based process GO:0007017 210 0.073
nucleoside triphosphate catabolic process GO:0009143 394 0.073
nucleoside triphosphate metabolic process GO:0009141 422 0.072
reproductive process GO:0022414 106 0.068
protein localization to membrane GO:0072657 160 0.068
regulation of mitotic cell cycle GO:0007346 189 0.068
organophosphate catabolic process GO:0046434 430 0.066
neuron differentiation GO:0030182 138 0.065
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.063
positive regulation of mitochondrial depolarization GO:0051901 3 0.062
regulation of cysteine type endopeptidase activity GO:2000116 127 0.060
nervous system development GO:0007399 293 0.060
Fly
modification dependent protein catabolic process GO:0019941 209 0.060
purine containing compound catabolic process GO:0072523 411 0.060
spermatid differentiation GO:0048515 4 0.057
neuron projection morphogenesis GO:0048812 50 0.057
Fly
mitochondrial transport GO:0006839 60 0.055
spindle organization GO:0007051 53 0.055
apoptotic signaling pathway GO:0097190 268 0.054
positive regulation of hydrolase activity GO:0051345 331 0.053
developmental process involved in reproduction GO:0003006 66 0.051
purine ribonucleoside catabolic process GO:0046130 398 0.050
protein localization to organelle GO:0033365 280 0.048
positive regulation of gtpase activity GO:0043547 166 0.048
reproductive structure development GO:0048608 55 0.048
ribosome biogenesis GO:0042254 48 0.048
ribonucleotide catabolic process GO:0009261 405 0.047
regulation of peptidase activity GO:0052547 180 0.047
single organism reproductive process GO:0044702 98 0.044
positive regulation of gtp catabolic process GO:0033126 166 0.044
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.042
spindle elongation GO:0051231 4 0.042
regulation of cellular response to stress GO:0080135 244 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
cyclic nucleotide catabolic process GO:0009214 9 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
protein modification by small protein conjugation GO:0032446 342 0.038
mitochondrion organization GO:0007005 156 0.036
single organism cellular localization GO:1902580 332 0.035
autophagic cell death GO:0048102 3 0.034
multicellular organismal reproductive process GO:0048609 40 0.034
multicellular organism reproduction GO:0032504 42 0.034
purine nucleoside triphosphate catabolic process GO:0009146 392 0.034
energy derivation by oxidation of organic compounds GO:0015980 43 0.032
negative regulation of phagocytosis GO:0050765 4 0.032
regulation of proteasomal protein catabolic process GO:0061136 87 0.032
behavior GO:0007610 112 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
plasma membrane organization GO:0007009 115 0.031
oocyte differentiation GO:0009994 2 0.031
rrna processing GO:0006364 35 0.031
neuron development GO:0048666 113 0.031
Fly
zymogen activation GO:0031638 70 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
negative regulation of protein metabolic process GO:0051248 391 0.030
circulatory system development GO:0072359 262 0.030
mitotic cell cycle process GO:1903047 286 0.030
generation of neurons GO:0048699 152 0.030
Fly
positive regulation of programmed cell death GO:0043068 249 0.029
regulation of nucleotide catabolic process GO:0030811 205 0.029
cellular response to dna damage stimulus GO:0006974 379 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
secretion GO:0046903 254 0.027
ribonucleoside catabolic process GO:0042454 406 0.026
regulation of striated muscle cell apoptotic process GO:0010662 3 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
motor neuron axon guidance GO:0008045 2 0.026
nucleoside catabolic process GO:0009164 408 0.025
chemotaxis GO:0006935 157 0.025
response to oxygen containing compound GO:1901700 369 0.025
protein maturation GO:0051604 233 0.025
maintenance of location GO:0051235 112 0.025
gonad development GO:0008406 34 0.024
positive regulation of nucleotide catabolic process GO:0030813 185 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
response to inorganic substance GO:0010035 127 0.024
secretion by cell GO:0032940 226 0.024
chemical homeostasis GO:0048878 306 0.024
sexual reproduction GO:0019953 37 0.024
convergent extension involved in gastrulation GO:0060027 1 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
oocyte development GO:0048599 1 0.023
spermatogenesis GO:0007283 22 0.023
regulation of establishment of cell polarity GO:2000114 5 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
ribosomal small subunit biogenesis GO:0042274 13 0.022
cellular macromolecule catabolic process GO:0044265 380 0.021
protein secretion GO:0009306 98 0.021
male gamete generation GO:0048232 22 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
glial cell migration GO:0008347 4 0.021
camp catabolic process GO:0006198 8 0.021
aging GO:0007568 66 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
gtp catabolic process GO:0006184 237 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
cuticle development GO:0042335 1 0.019
regulation of gtpase activity GO:0043087 180 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.018
locomotory behavior GO:0007626 1 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
positive regulation of cell death GO:0010942 263 0.018
ncrna processing GO:0034470 83 0.018
protein homooligomerization GO:0051260 100 0.018
cellular homeostasis GO:0019725 196 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
positive regulation of growth GO:0045927 58 0.018
ribonucleoprotein complex biogenesis GO:0022613 116 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
protein deubiquitination GO:0016579 79 0.017
negative regulation of endocytosis GO:0045806 19 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
de novo protein folding GO:0006458 2 0.017
cell projection morphogenesis GO:0048858 129 0.017
Fly
regulation of translational elongation GO:0006448 2 0.017
regulation of protein localization to plasma membrane GO:1903076 40 0.016
regulation of generation of precursor metabolites and energy GO:0043467 27 0.016
single organism membrane organization GO:0044802 268 0.016
somitogenesis GO:0001756 2 0.016
tube development GO:0035295 125 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
cellular respiration GO:0045333 21 0.016
negative regulation of catalytic activity GO:0043086 335 0.015
microtubule organizing center organization GO:0031023 62 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
atp transport GO:0015867 4 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
spermatid development GO:0007286 4 0.015
myoblast migration GO:0051451 1 0.015
gamete generation GO:0007276 25 0.014
protein localization to plasma membrane GO:0072659 93 0.014
molting cycle GO:0042303 28 0.014
regeneration GO:0031099 4 0.014
positive regulation of cyclic nucleotide phosphodiesterase activity GO:0051343 4 0.014
transmembrane transport GO:0055085 399 0.014
rna splicing GO:0008380 131 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
mrna catabolic process GO:0006402 56 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
purine nucleotide catabolic process GO:0006195 405 0.013
regulation of growth GO:0040008 165 0.013
regulation of protein complex assembly GO:0043254 147 0.013
mitotic spindle organization GO:0007052 27 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
negative regulation of cell death GO:0060548 345 0.013
actin filament based process GO:0030029 224 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
muscle cell cellular homeostasis GO:0046716 3 0.012
regulation of hydrogen peroxide induced cell death GO:1903205 10 0.012
gtp metabolic process GO:0046039 239 0.012
regulation of feeding behavior GO:0060259 3 0.012
protein targeting GO:0006605 187 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
mrna splicing via spliceosome GO:0000398 89 0.011
chromosome segregation GO:0007059 114 0.011
regulation of cellular component movement GO:0051270 334 0.011
mrna metabolic process GO:0016071 175 0.011
thymus development GO:0048538 3 0.011
ion homeostasis GO:0050801 230 0.011
regulation of protein localization GO:0032880 296 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
negative regulation of protein modification process GO:0031400 200 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
centrosome duplication GO:0051298 28 0.011
negative regulation of transferase activity GO:0051348 124 0.011
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.011
convergent extension GO:0060026 1 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
negative regulation of transport GO:0051051 176 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
lipid localization GO:0010876 106 0.010
cytokinesis GO:0000910 96 0.010
cell growth GO:0016049 160 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
regulation of mapk cascade GO:0043408 262 0.010
ncrna metabolic process GO:0034660 108 0.010

EIF3L disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.010
anemia DOID:2355 55 0.010
hematopoietic system disease DOID:74 100 0.010