Homo sapiens

157 known processes

EIF4A3

eukaryotic translation initiation factor 4A3

(Aliases: DDX48,NUK34,MGC10862,eIF4AIII,NMP265,KIAA0111,DKFZp686O16189)

EIF4A3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 175 1.000
rna processing GO:0006396 255 1.000
Yeast Mouse Fly
mrna processing GO:0006397 133 1.000
Mouse
spliceosomal complex assembly GO:0000245 17 1.000
mrna splicing via spliceosome GO:0000398 89 1.000
Mouse
rna splicing GO:0008380 131 1.000
Mouse Fly
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 1.000
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.998
mrna export from nucleus GO:0006406 29 0.997
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.996
Mouse
regulation of mrna processing GO:0050684 48 0.996
Mouse
rna splicing via transesterification reactions GO:0000375 90 0.996
Mouse
anterior posterior axis specification embryo GO:0008595 2 0.990
Fly
regulation of mrna splicing via spliceosome GO:0048024 32 0.973
Mouse
regulation of mrna metabolic process GO:1903311 53 0.972
Mouse
rna catabolic process GO:0006401 71 0.965
positive regulation of mrna metabolic process GO:1903313 19 0.957
Mouse
intracellular mrna localization GO:0008298 1 0.953
Fly
cellular macromolecular complex assembly GO:0034622 324 0.951
segmentation GO:0035282 4 0.941
Fly
mrna catabolic process GO:0006402 56 0.937
oogenesis GO:0048477 2 0.928
Fly
regulation of rna splicing GO:0043484 62 0.924
Mouse
rna transport GO:0050658 39 0.922
regulation of oocyte development GO:0060281 1 0.920
small gtpase mediated signal transduction GO:0007264 78 0.916
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.915
Fly
microtubule based process GO:0007017 210 0.893
rna export from nucleus GO:0006405 33 0.880
nucleobase containing compound transport GO:0015931 51 0.879
rna localization GO:0006403 41 0.854
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.841
anterior posterior axis specification GO:0009948 2 0.838
Fly
alternative mrna splicing via spliceosome GO:0000380 27 0.834
post embryonic development GO:0009791 2 0.828
Worm
organophosphate catabolic process GO:0046434 430 0.827
microtubule cytoskeleton organization GO:0000226 176 0.812
protein complex disassembly GO:0043241 52 0.785
gonad development GO:0008406 34 0.766
Worm
mrna transport GO:0051028 30 0.761
regulation of meiosis GO:0040020 3 0.744
Worm
ras protein signal transduction GO:0007265 73 0.743
Fly
female gamete generation GO:0007292 2 0.738
Fly
positive regulation of dna templated transcription elongation GO:0032786 18 0.716
purine nucleoside catabolic process GO:0006152 398 0.704
regulation of cell differentiation GO:0045595 393 0.664
positive regulation of mrna processing GO:0050685 17 0.663
Mouse
embryo development GO:0009790 123 0.643
regulation of cell maturation GO:1903429 3 0.640
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.624
nucleoside triphosphate catabolic process GO:0009143 394 0.622
translation GO:0006412 132 0.615
atp catabolic process GO:0006200 157 0.572
cellular macromolecule catabolic process GO:0044265 380 0.571
nucleus localization GO:0051647 1 0.561
single organism cellular localization GO:1902580 332 0.548
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.546
oocyte development GO:0048599 1 0.545
Fly
locomotory behavior GO:0007626 1 0.539
ribonucleoside monophosphate catabolic process GO:0009158 158 0.539
mrna splice site selection GO:0006376 7 0.530
purine nucleoside triphosphate catabolic process GO:0009146 392 0.515
nucleic acid transport GO:0050657 39 0.513
cellular response to dna damage stimulus GO:0006974 379 0.511
Fly
erk1 and erk2 cascade GO:0070371 104 0.474
Fly
regulation of meiotic cell cycle GO:0051445 4 0.470
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.467
intracellular transport of virus GO:0075733 14 0.464
regulation of dna templated transcription elongation GO:0032784 23 0.454
nuclear transcribed mrna catabolic process GO:0000956 48 0.441
nuclear migration GO:0007097 1 0.439
macromolecular complex disassembly GO:0032984 60 0.426
developmental process involved in reproduction GO:0003006 66 0.421
Worm Fly
reproductive system development GO:0061458 56 0.418
Worm
single organism reproductive process GO:0044702 98 0.417
Worm Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.410
establishment of nucleus localization GO:0040023 1 0.409
cellular component disassembly GO:0022411 92 0.403
embryonic pattern specification GO:0009880 5 0.400
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.389
mapk cascade GO:0000165 288 0.375
Fly
multi organism localization GO:1902579 14 0.362
dna templated transcription elongation GO:0006354 25 0.342
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.337
oocyte differentiation GO:0009994 2 0.330
Fly
positive regulation of mapk cascade GO:0043410 190 0.322
Fly
purine nucleoside monophosphate catabolic process GO:0009128 158 0.316
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.302
viral mrna export from host cell nucleus GO:0046784 8 0.287
female sex determination GO:0030237 1 0.283
reproductive structure development GO:0048608 55 0.279
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.262
guanosine containing compound catabolic process GO:1901069 239 0.261
multicellular organismal aging GO:0010259 3 0.257
nuclear transport GO:0051169 179 0.254
regulation of erk1 and erk2 cascade GO:0070372 99 0.222
Fly
purine containing compound catabolic process GO:0072523 411 0.220
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.216
positive regulation of phosphorylation GO:0042327 394 0.212
Fly
mitotic cell cycle GO:0000278 326 0.202
regulation of mapk cascade GO:0043408 262 0.201
Fly
regulation of atp metabolic process GO:1903578 29 0.199
mitotic cell cycle process GO:1903047 286 0.195
mrna 5 splice site recognition GO:0000395 3 0.193
determination of adult lifespan GO:0008340 2 0.192
nucleocytoplasmic transport GO:0006913 176 0.192
development of primary sexual characteristics GO:0045137 35 0.191
Worm
osteoblast differentiation GO:0001649 92 0.183
nucleotide catabolic process GO:0009166 408 0.182
single fertilization GO:0007338 11 0.178
viral process GO:0016032 146 0.178
nuclear mrna surveillance GO:0071028 4 0.177
regulation of nucleoside metabolic process GO:0009118 209 0.175
nuclear division GO:0000280 128 0.166
Worm
signal transduction by phosphorylation GO:0023014 297 0.163
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.158
single organism nuclear import GO:1902593 104 0.156
regulation of translation GO:0006417 89 0.154
mrna 3 end processing GO:0031124 24 0.152
reproduction GO:0000003 63 0.147
Worm Fly
cytoplasmic transport GO:0016482 379 0.146
embryonic axis specification GO:0000578 5 0.138
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.138
mrna cis splicing via spliceosome GO:0045292 7 0.137
regulation of purine nucleotide metabolic process GO:1900542 264 0.131
reproductive process GO:0022414 106 0.130
Worm Fly
nucleoside catabolic process GO:0009164 408 0.128
cytokinesis GO:0000910 96 0.128
positive regulation of developmental process GO:0051094 314 0.124
ossification GO:0001503 121 0.119
regulation of nucleotide metabolic process GO:0006140 269 0.116
sex differentiation GO:0007548 45 0.112
Worm
cell division GO:0051301 168 0.112
Worm
pattern specification process GO:0007389 43 0.111
Fly
regionalization GO:0003002 29 0.111
Fly
viral life cycle GO:0019058 132 0.102
regulation of atpase activity GO:0043462 25 0.100
atp metabolic process GO:0046034 176 0.099
nucleoside triphosphate metabolic process GO:0009141 422 0.096
ribonucleoprotein complex subunit organization GO:0071826 81 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.085
ribonucleoside catabolic process GO:0042454 406 0.082
regulation of dna metabolic process GO:0051052 153 0.081
regulation of atp catabolic process GO:1903289 25 0.080
poly a mrna export from nucleus GO:0016973 6 0.080
trna 3 end processing GO:0042780 3 0.076
interspecies interaction between organisms GO:0044419 156 0.076
neurogenesis GO:0022008 169 0.075
dorsal ventral axis specification GO:0009950 7 0.074
establishment of rna localization GO:0051236 39 0.074
mitotic nuclear division GO:0007067 119 0.071
cell development GO:0048468 328 0.071
Worm Fly
regulation of cellular component biogenesis GO:0044087 281 0.071
anterior posterior pattern specification GO:0009952 9 0.070
Fly
spliceosomal snrnp assembly GO:0000387 28 0.070
growth GO:0040007 202 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.069
nucleosome assembly GO:0006334 50 0.068
multi organism intracellular transport GO:1902583 14 0.067
multi organism cellular process GO:0044764 156 0.067
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.066
regulation of embryonic development GO:0045995 20 0.065
regulation of response to dna damage stimulus GO:2001020 94 0.065
dna recombination GO:0006310 77 0.064
positive regulation of atpase activity GO:0032781 19 0.062
purine ribonucleotide catabolic process GO:0009154 404 0.060
regulation of cell development GO:0060284 161 0.059
positive regulation of nucleotide metabolic process GO:0045981 230 0.059
erbb signaling pathway GO:0038127 44 0.058
organelle localization GO:0051640 84 0.058
nuclear export GO:0051168 69 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.055
blastoderm segmentation GO:0007350 2 0.053
Fly
cell adhesion GO:0007155 325 0.053
vesicle mediated transport GO:0016192 371 0.053
epidermal growth factor receptor signaling pathway GO:0007173 39 0.052
multicellular organism reproduction GO:0032504 42 0.051
Worm Fly
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.050
lipid metabolic process GO:0006629 381 0.050
negative regulation of protein dephosphorylation GO:0035308 3 0.049
intracellular protein transport GO:0006886 270 0.048
axis specification GO:0009798 12 0.048
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.047
immune effector process GO:0002252 159 0.046
positive regulation of ras protein signal transduction GO:0046579 12 0.046
Fly
regulation of multi organism process GO:0043900 157 0.046
dna replication independent nucleosome assembly GO:0006336 27 0.046
nucleoside monophosphate metabolic process GO:0009123 191 0.045
regulation of cellular response to stress GO:0080135 244 0.044
spindle organization GO:0007051 53 0.044
regulation of nucleotide catabolic process GO:0030811 205 0.044
developmental maturation GO:0021700 28 0.044
Fly
regulation of reproductive process GO:2000241 15 0.042
positive regulation of gtp catabolic process GO:0033126 166 0.042
nitrogen compound transport GO:0071705 191 0.041
multi organism transport GO:0044766 14 0.040
regulation of cell division GO:0051302 116 0.040
Worm
gtp metabolic process GO:0046039 239 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
protein dna complex assembly GO:0065004 64 0.039
cellular protein complex disassembly GO:0043624 36 0.039
negative regulation of protein metabolic process GO:0051248 391 0.039
regeneration GO:0031099 4 0.039
sexual reproduction GO:0019953 37 0.038
Worm Fly
putrescine metabolic process GO:0009445 2 0.037
regulation of ras protein signal transduction GO:0046578 155 0.037
Fly
negative regulation of cell differentiation GO:0045596 171 0.036
endocytosis GO:0006897 159 0.035
apoptotic signaling pathway GO:0097190 268 0.034
negative regulation of multicellular organismal process GO:0051241 317 0.034
protein stabilization GO:0050821 64 0.033
protein localization to organelle GO:0033365 280 0.033
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.032
negative regulation of locomotion GO:0040013 118 0.031
dna damage checkpoint GO:0000077 68 0.031
epithelial cell differentiation GO:0030855 141 0.031
establishment of ribosome localization GO:0033753 4 0.031
sex determination GO:0007530 3 0.031
protein targeting to nucleus GO:0044744 104 0.030
negative regulation of atpase activity GO:0032780 5 0.030
negative regulation of megakaryocyte differentiation GO:0045653 16 0.029
dna repair GO:0006281 198 0.029
defense response GO:0006952 315 0.029
establishment of organelle localization GO:0051656 59 0.029
positive regulation of translation GO:0045727 35 0.029
negative regulation of immune system process GO:0002683 136 0.029
blastocyst development GO:0001824 3 0.029
cofactor metabolic process GO:0051186 87 0.028
photoreceptor cell differentiation GO:0046530 2 0.027
protein import GO:0017038 130 0.027
negative regulation of cellular component organization GO:0051129 235 0.026
wound healing GO:0042060 115 0.026
genitalia development GO:0048806 10 0.026
Worm
regulation of cell cycle process GO:0010564 266 0.026
Worm
negative regulation of cellular component movement GO:0051271 106 0.026
multicellular organismal reproductive process GO:0048609 40 0.025
Worm Fly
positive regulation of rna splicing GO:0033120 12 0.025
Mouse
oxidation reduction process GO:0055114 396 0.025
negative regulation of cell cycle checkpoint GO:1901977 4 0.025
biological adhesion GO:0022610 331 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
tripartite regional subdivision GO:0007351 2 0.024
Fly
negative regulation of cell motility GO:2000146 104 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
establishment or maintenance of cell polarity GO:0007163 31 0.022
toxin transport GO:1901998 4 0.022
mitotic spindle organization GO:0007052 27 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
negative regulation of epithelial cell differentiation GO:0030857 6 0.022
meiotic nuclear division GO:0007126 10 0.022
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.022
Yeast
ribonucleotide catabolic process GO:0009261 405 0.021
nervous system development GO:0007399 293 0.021
glycerophospholipid metabolic process GO:0006650 84 0.021
dna dependent dna replication GO:0006261 44 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
rna 3 end processing GO:0031123 35 0.021
cellular hyperosmotic response GO:0071474 4 0.020
regulation of cell motility GO:2000145 299 0.020
7 methylguanosine rna capping GO:0009452 9 0.020
cytokine production GO:0001816 247 0.020
regulation of cell migration GO:0030334 289 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.019
chordate embryonic development GO:0043009 34 0.019
regulation of protein complex disassembly GO:0043244 28 0.019
regulation of locomotion GO:0040012 329 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.018
Yeast
regulation of spindle checkpoint GO:0090231 12 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
glycerolipid metabolic process GO:0046486 107 0.018
generation of neurons GO:0048699 152 0.018
7 methylguanosine mrna capping GO:0006370 7 0.018
regulation of growth GO:0040008 165 0.018
fertilization GO:0009566 12 0.018
eye photoreceptor cell differentiation GO:0001754 2 0.017
negative regulation of multi organism process GO:0043901 92 0.017
adult locomotory behavior GO:0008344 1 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
tissue migration GO:0090130 119 0.017
rna interference GO:0016246 4 0.017
cell maturation GO:0048469 11 0.017
Fly
germ cell development GO:0007281 8 0.017
Worm Fly
receptor mediated endocytosis GO:0006898 84 0.017
regulation of cell cycle GO:0051726 393 0.017
Worm
negative regulation of rna splicing GO:0033119 15 0.016
response to osmotic stress GO:0006970 17 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
ameboidal type cell migration GO:0001667 135 0.016
nuclear import GO:0051170 106 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.015
negative regulation of dna damage checkpoint GO:2000002 4 0.015
regulation of cellular component movement GO:0051270 334 0.015
aging GO:0007568 66 0.015
regulation of dna recombination GO:0000018 23 0.015
response to drug GO:0042493 81 0.015
epithelium migration GO:0090132 119 0.015
signal transduction by p53 class mediator GO:0072331 72 0.015
cellular response to cytokine stimulus GO:0071345 181 0.014
epithelial cell proliferation GO:0050673 128 0.014
regulation of cytokine production GO:0001817 232 0.014
protein targeting GO:0006605 187 0.014
regulation of cell growth GO:0001558 135 0.014
positive regulation of immune system process GO:0002684 283 0.013
hemopoiesis GO:0030097 180 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
microtubule organizing center organization GO:0031023 62 0.013
molting cycle GO:0042303 28 0.013
Worm
organelle fission GO:0048285 149 0.012
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
gamete generation GO:0007276 25 0.012
Worm Fly
negative regulation of translation GO:0017148 37 0.012
dna integrity checkpoint GO:0031570 71 0.012
amine biosynthetic process GO:0009309 4 0.012
transcription coupled nucleotide excision repair GO:0006283 8 0.012
megakaryocyte differentiation GO:0030219 25 0.012
regulation of nuclear division GO:0051783 65 0.012
Worm
positive regulation of programmed cell death GO:0043068 249 0.012
innate immune response activating signal transduction GO:0002758 48 0.011
regulation of protein binding GO:0043393 66 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.011
male sex differentiation GO:0046661 25 0.011
innate immune response GO:0045087 178 0.011
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.010
Worm Fly
polyamine metabolic process GO:0006595 4 0.010
protein import into mitochondrial matrix GO:0030150 1 0.010
myeloid cell differentiation GO:0030099 117 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
positive regulation of atp metabolic process GO:1903580 20 0.010
organ morphogenesis GO:0009887 147 0.010
negative regulation of peptidyl serine dephosphorylation GO:1902309 1 0.010
primary mirna processing GO:0031053 3 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
blood circulation GO:0008015 113 0.010
epidermal cell differentiation GO:0009913 45 0.010

EIF4A3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.013
central nervous system disease DOID:331 186 0.010
nervous system disease DOID:863 431 0.010