Homo sapiens

73 known processes

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

(Aliases: BP-1,PHAS-I,4EBP1,MGC4316,4E-BP1)

EIF4EBP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
serine family amino acid metabolic process GO:0009069 12 0.801
cellular amino acid metabolic process GO:0006520 116 0.536
positive regulation of cellular amine metabolic process GO:0033240 7 0.396
cellular response to nitrogen compound GO:1901699 144 0.388
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.386
regulation of tor signaling GO:0032006 30 0.352
vitamin metabolic process GO:0006766 26 0.339
positive regulation of tor signaling GO:0032008 11 0.323
dicarboxylic acid metabolic process GO:0043648 29 0.306
response to nitrogen compound GO:1901698 184 0.305
Mouse
post embryonic development GO:0009791 2 0.283
coenzyme metabolic process GO:0006732 65 0.262
one carbon metabolic process GO:0006730 1 0.256
response to oxygen containing compound GO:1901700 369 0.246
Mouse Rat
cellular response to oxygen containing compound GO:1901701 276 0.240
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.237
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.235
glycine metabolic process GO:0006544 4 0.235
organonitrogen compound biosynthetic process GO:1901566 200 0.230
positive regulation of mitotic cell cycle GO:0045931 60 0.222
l serine metabolic process GO:0006563 5 0.220
alpha amino acid metabolic process GO:1901605 72 0.216
carbohydrate metabolic process GO:0005975 207 0.212
cofactor metabolic process GO:0051186 87 0.198
oxidation reduction process GO:0055114 396 0.178
positive regulation of transferase activity GO:0051347 227 0.170
response to organonitrogen compound GO:0010243 156 0.162
Mouse
transcription from rna polymerase iii promoter GO:0006383 19 0.158
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.147
organic acid catabolic process GO:0016054 71 0.146
regulation of cellular ketone metabolic process GO:0010565 50 0.145
cellular ketone metabolic process GO:0042180 80 0.145
tor signaling GO:0031929 39 0.143
regulation of cellular amino acid metabolic process GO:0006521 6 0.140
single organism carbohydrate metabolic process GO:0044723 193 0.137
cellular amine metabolic process GO:0044106 41 0.137
regulation of cell growth GO:0001558 135 0.129
somatic muscle development GO:0007525 1 0.128
alpha amino acid catabolic process GO:1901606 26 0.128
cellular response to external stimulus GO:0071496 111 0.123
positive regulation of rho guanyl nucleotide exchange factor activity GO:2001108 1 0.120
positive regulation of protein kinase activity GO:0045860 190 0.119
cellular amino acid catabolic process GO:0009063 31 0.116
response to biotic stimulus GO:0009607 276 0.114
monocarboxylic acid metabolic process GO:0032787 185 0.106
translational initiation GO:0006413 48 0.105
cellular response to organonitrogen compound GO:0071417 124 0.101
Mouse
amine metabolic process GO:0009308 44 0.098
modified amino acid transport GO:0072337 11 0.096
purine nucleobase biosynthetic process GO:0009113 3 0.096
cellular response to starvation GO:0009267 58 0.094
water soluble vitamin metabolic process GO:0006767 6 0.093
regulation of transferase activity GO:0051338 355 0.091
response to organic cyclic compound GO:0014070 204 0.087
ion transmembrane transport GO:0034220 338 0.084
syncytium formation by plasma membrane fusion GO:0000768 2 0.082
regulation of protein kinase activity GO:0045859 289 0.081
regulation of protein serine threonine kinase activity GO:0071900 179 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.078
regulation of translation GO:0006417 89 0.077
small molecule catabolic process GO:0044282 92 0.077
regulation of mitotic cell cycle GO:0007346 189 0.076
regulation of cellular component size GO:0032535 82 0.072
protein oligomerization GO:0051259 173 0.071
response to amino acid GO:0043200 14 0.071
female gamete generation GO:0007292 2 0.071
proline transport GO:0015824 4 0.068
sulfur compound metabolic process GO:0006790 101 0.067
glycosyl compound catabolic process GO:1901658 413 0.067
regulation of rho guanyl nucleotide exchange factor activity GO:2001106 1 0.066
alanine transport GO:0032328 3 0.066
negative regulation of protein metabolic process GO:0051248 391 0.064
oogenesis GO:0048477 2 0.063
ribonucleoside triphosphate catabolic process GO:0009203 391 0.063
response to starvation GO:0042594 59 0.062
response to hormone GO:0009725 175 0.062
Mouse
hexose metabolic process GO:0019318 55 0.061
l alanine transport GO:0015808 3 0.058
positive regulation of phosphorylation GO:0042327 394 0.057
response to peptide hormone GO:0043434 61 0.056
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.054
glutamine family amino acid metabolic process GO:0009064 17 0.053
positive regulation of cell size GO:0045793 3 0.052
regulation of kinase activity GO:0043549 314 0.052
positive regulation of kinase activity GO:0033674 204 0.052
regulation of anatomical structure size GO:0090066 101 0.052
response to acid chemical GO:0001101 66 0.052
cellular macromolecular complex assembly GO:0034622 324 0.051
response to peptide GO:1901652 65 0.051
Mouse
cell growth GO:0016049 160 0.050
positive regulation of cellular catabolic process GO:0031331 284 0.049
negative regulation of phosphorus metabolic process GO:0010563 267 0.048
inorganic ion transmembrane transport GO:0098660 231 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
mitotic cell cycle process GO:1903047 286 0.046
negative regulation of cell proliferation GO:0008285 228 0.045
transmembrane transport GO:0055085 399 0.045
nucleobase biosynthetic process GO:0046112 4 0.045
lipid biosynthetic process GO:0008610 177 0.045
protein polymerization GO:0051258 71 0.044
carboxylic acid catabolic process GO:0046395 71 0.044
cellular response to nutrient levels GO:0031669 69 0.043
monosaccharide metabolic process GO:0005996 74 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.042
positive regulation of transport GO:0051050 336 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.041
negative regulation of catalytic activity GO:0043086 335 0.041
cellular response to hormone stimulus GO:0032870 125 0.041
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.041
fatty acid metabolic process GO:0006631 115 0.040
response to lipid GO:0033993 206 0.040
determination of adult lifespan GO:0008340 2 0.040
chloride transmembrane transport GO:1902476 38 0.039
small molecule biosynthetic process GO:0044283 157 0.039
response to other organism GO:0051707 261 0.039
serine family amino acid catabolic process GO:0009071 5 0.039
purine containing compound biosynthetic process GO:0072522 88 0.039
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.038
anatomical structure formation involved in morphogenesis GO:0048646 284 0.038
purine containing compound catabolic process GO:0072523 411 0.038
lipid localization GO:0010876 106 0.037
anion transport GO:0006820 161 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.037
organophosphate catabolic process GO:0046434 430 0.036
protein acylation GO:0043543 138 0.036
rna processing GO:0006396 255 0.036
response to nutrient levels GO:0031667 81 0.036
neurogenesis GO:0022008 169 0.036
response to oxidative stress GO:0006979 121 0.035
regulation of cell cycle GO:0051726 393 0.035
microtubule based process GO:0007017 210 0.034
organophosphate biosynthetic process GO:0090407 163 0.034
chemical homeostasis GO:0048878 306 0.034
nitrogen compound transport GO:0071705 191 0.034
growth GO:0040007 202 0.034
negative regulation of transferase activity GO:0051348 124 0.034
regulation of growth GO:0040008 165 0.033
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
response to abiotic stimulus GO:0009628 336 0.032
response to external biotic stimulus GO:0043207 261 0.032
biological adhesion GO:0022610 331 0.032
regeneration GO:0031099 4 0.032
rho protein signal transduction GO:0007266 26 0.031
protein catabolic process GO:0030163 325 0.031
cation transmembrane transport GO:0098655 238 0.031
ribonucleoside catabolic process GO:0042454 406 0.031
cellular response to amino acid stimulus GO:0071230 12 0.030
negative regulation of phosphorylation GO:0042326 174 0.030
multicellular organismal aging GO:0010259 3 0.030
inorganic anion transmembrane transport GO:0098661 47 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
small gtpase mediated signal transduction GO:0007264 78 0.030
cell adhesion GO:0007155 325 0.029
regulation of cellular response to stress GO:0080135 244 0.029
negative regulation of hydrolase activity GO:0051346 182 0.029
response to extracellular stimulus GO:0009991 85 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
positive regulation of organelle organization GO:0010638 195 0.028
system process GO:0003008 349 0.028
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.028
regulation of response to drug GO:2001023 3 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
hormone secretion GO:0046879 65 0.027
organelle assembly GO:0070925 176 0.027
response to steroid hormone GO:0048545 80 0.027
regulation of cytokine production GO:0001817 232 0.027
nucleotide catabolic process GO:0009166 408 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
cation transport GO:0006812 331 0.026
negative regulation of developmental process GO:0051093 247 0.026
anion transmembrane transport GO:0098656 76 0.025
epithelium development GO:0060429 227 0.025
negative regulation of nfat protein import into nucleus GO:0051534 2 0.025
cellular response to extracellular stimulus GO:0031668 72 0.025
regulation of response to external stimulus GO:0032101 222 0.025
organelle fission GO:0048285 149 0.025
positive regulation of rho protein signal transduction GO:0035025 4 0.025
cellular response to acid chemical GO:0071229 44 0.025
dna catabolic process GO:0006308 49 0.025
negative regulation of cell size GO:0045792 3 0.025
negative regulation of cellular component organization GO:0051129 235 0.024
Rat
negative regulation of programmed cell death GO:0043069 321 0.024
maintenance of location GO:0051235 112 0.024
regulation of cytoskeleton organization GO:0051493 177 0.024
cellular protein catabolic process GO:0044257 261 0.024
regulation of immune response GO:0050776 201 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
cell cycle phase transition GO:0044770 173 0.023
enzyme linked receptor protein signaling pathway GO:0007167 303 0.023
Mouse
protein tetramerization GO:0051262 47 0.023
striated muscle cell differentiation GO:0051146 43 0.023
actin filament based process GO:0030029 224 0.023
trna metabolic process GO:0006399 35 0.023
dna repair GO:0006281 198 0.023
segmentation GO:0035282 4 0.022
negative regulation of kinase activity GO:0033673 106 0.022
cell cycle g1 s phase transition GO:0044843 80 0.022
negative regulation of organelle organization GO:0010639 126 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
chromatin organization GO:0006325 351 0.022
negative regulation of protein modification process GO:0031400 200 0.022
cellular protein complex assembly GO:0043623 188 0.021
positive regulation of catabolic process GO:0009896 310 0.021
g1 s transition of mitotic cell cycle GO:0000082 78 0.021
positive regulation of cell cycle GO:0045787 140 0.021
mitochondrion organization GO:0007005 156 0.021
positive regulation of cell death GO:0010942 263 0.021
endocytosis GO:0006897 159 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
organic anion transport GO:0015711 103 0.020
secretion by cell GO:0032940 226 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
regulation of protein transport GO:0051223 213 0.019
spindle elongation GO:0051231 4 0.019
organic acid transport GO:0015849 65 0.019
cytokine production GO:0001816 247 0.019
vesicle mediated transport GO:0016192 371 0.019
cellular lipid catabolic process GO:0044242 65 0.019
secretion GO:0046903 254 0.019
response to virus GO:0009615 126 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
alanine metabolic process GO:0006522 4 0.018
ncrna metabolic process GO:0034660 108 0.018
nucleotide biosynthetic process GO:0009165 109 0.018
cell morphogenesis GO:0000902 296 0.018
single organism cellular localization GO:1902580 332 0.018
myoblast fusion GO:0007520 1 0.018
epithelial cell proliferation GO:0050673 128 0.018
cell activation GO:0001775 213 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
cellular lipid metabolic process GO:0044255 303 0.018
amino acid activation GO:0043038 12 0.018
cellular response to lipid GO:0071396 127 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
immune response GO:0006955 307 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
regulation of cell cycle process GO:0010564 266 0.017
regulation of cell differentiation GO:0045595 393 0.017
cytoplasmic transport GO:0016482 379 0.016
regulation of metal ion transport GO:0010959 120 0.016
regulation of lipid biosynthetic process GO:0046890 47 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
pteridine containing compound metabolic process GO:0042558 7 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
mapk cascade GO:0000165 288 0.016
actin filament organization GO:0007015 128 0.015
central nervous system development GO:0007417 123 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
inorganic anion transport GO:0015698 60 0.015
nuclear transport GO:0051169 179 0.015
oocyte differentiation GO:0009994 2 0.015
regulation of locomotion GO:0040012 329 0.015
regulation of secretion GO:0051046 194 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
regulation of cellular component movement GO:0051270 334 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
cellular component disassembly GO:0022411 92 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
aging GO:0007568 66 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
rna interference GO:0016246 4 0.014
negative regulation of cell death GO:0060548 345 0.014
spermatid development GO:0007286 4 0.014
pigment biosynthetic process GO:0046148 10 0.014
cell type specific apoptotic process GO:0097285 125 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of mapk cascade GO:0043408 262 0.014
positive regulation of protein complex assembly GO:0031334 86 0.014
sulfur amino acid transport GO:0000101 2 0.014
regulation of actin polymerization or depolymerization GO:0008064 56 0.014
carboxylic acid transport GO:0046942 63 0.014
regulation of multi organism process GO:0043900 157 0.014
rac protein signal transduction GO:0016601 12 0.014
gonad development GO:0008406 34 0.014
amino acid transmembrane transport GO:0003333 20 0.014
divalent inorganic cation transport GO:0072511 158 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
meiotic chromosome segregation GO:0045132 4 0.014
hemopoiesis GO:0030097 180 0.014
regulation of leukocyte activation GO:0002694 115 0.013
metal ion transport GO:0030001 272 0.013
response to molecule of bacterial origin GO:0002237 82 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
fatty acid biosynthetic process GO:0006633 46 0.013
immune effector process GO:0002252 159 0.013
negative regulation of cell cycle GO:0045786 193 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
glucose homeostasis GO:0042593 31 0.013
cellular homeostasis GO:0019725 196 0.013
head development GO:0060322 108 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
regulation of actin filament length GO:0030832 56 0.013
generation of neurons GO:0048699 152 0.013
regulation of map kinase activity GO:0043405 108 0.013
glucose metabolic process GO:0006006 45 0.013
positive regulation of proteolysis GO:0045862 142 0.013
regulation of hormone levels GO:0010817 125 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
stress activated mapk cascade GO:0051403 93 0.013
defense response to other organism GO:0098542 129 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
dna packaging GO:0006323 77 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
muscle cell differentiation GO:0042692 63 0.013
cell projection organization GO:0030030 252 0.012
peptide secretion GO:0002790 51 0.012
lipid metabolic process GO:0006629 381 0.012
smooth muscle cell proliferation GO:0048659 28 0.012
nervous system development GO:0007399 293 0.012
d aspartate import GO:0070779 3 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
developmental process involved in reproduction GO:0003006 66 0.012
pyruvate metabolic process GO:0006090 26 0.012
organic acid biosynthetic process GO:0016053 97 0.012
regulation of homeostatic process GO:0032844 121 0.012
nucleobase metabolic process GO:0009112 8 0.012
cellular glucose homeostasis GO:0001678 11 0.012
glucose transport GO:0015758 30 0.012
regulation of rho gtpase activity GO:0032319 66 0.012
defense response GO:0006952 315 0.012
microtubule organizing center organization GO:0031023 62 0.012
response to radiation GO:0009314 151 0.012
cellular modified amino acid metabolic process GO:0006575 64 0.012
response to oxygen levels GO:0070482 100 0.012
protein ubiquitination GO:0016567 314 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
neuron development GO:0048666 113 0.012
negative regulation of response to extracellular stimulus GO:0032105 5 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
divalent metal ion transport GO:0070838 152 0.012
protein autophosphorylation GO:0046777 123 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
regulation of rho protein signal transduction GO:0035023 79 0.012
regulation of secretion by cell GO:1903530 177 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
actin cytoskeleton organization GO:0030036 207 0.012
positive regulation of immune system process GO:0002684 283 0.012
spermatid differentiation GO:0048515 4 0.012
taurine metabolic process GO:0019530 1 0.011
amino acid import GO:0043090 4 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
regulation of protein localization GO:0032880 296 0.011
intracellular protein transport GO:0006886 270 0.011
establishment or maintenance of actin cytoskeleton polarity GO:0030950 1 0.011
epithelial cell differentiation GO:0030855 141 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
protein acetylation GO:0006473 116 0.011
cellular response to peptide GO:1901653 59 0.011
Mouse
single organism cell adhesion GO:0098602 179 0.011
rna catabolic process GO:0006401 71 0.011
regulation of protein import into nucleus GO:0042306 78 0.011
regulation of cell activation GO:0050865 125 0.011
negative regulation of cytokine production GO:0001818 82 0.011
calcium ion transport GO:0006816 147 0.011
chloride transport GO:0006821 41 0.011
multi organism reproductive process GO:0044703 54 0.011
taxis GO:0042330 157 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
l glutamate import GO:0051938 3 0.010
dephosphorylation GO:0016311 209 0.010
chemotaxis GO:0006935 157 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
response to growth factor GO:0070848 205 0.010
innate immune response GO:0045087 178 0.010
neurological system process GO:0050877 163 0.010
pyruvate family amino acid metabolic process GO:0009078 4 0.010
carbohydrate transport GO:0008643 37 0.010
regulation of membrane potential GO:0042391 95 0.010
fatty acid oxidation GO:0019395 31 0.010
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.010
peptidyl serine phosphorylation GO:0018105 101 0.010
positive regulation of immune response GO:0050778 159 0.010
cell division GO:0051301 168 0.010
positive regulation of protein polymerization GO:0032273 45 0.010
response to decreased oxygen levels GO:0036293 96 0.010
jnk cascade GO:0007254 80 0.010

EIF4EBP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.222
amino acid metabolic disorder DOID:9252 50 0.222
inherited metabolic disorder DOID:655 242 0.222
disease of mental health DOID:150 70 0.075
developmental disorder of mental health DOID:0060037 29 0.027
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013