Homo sapiens

42 known processes

EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

(Aliases: EIF-4G1,P220,DKFZp686A1451,EIF4GI,EIF4G,EIF4F)

EIF4G1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translation GO:0006412 132 1.000
regulation of translation GO:0006417 89 1.000
translational initiation GO:0006413 48 1.000
posttranscriptional regulation of gene expression GO:0010608 213 0.988
determination of adult lifespan GO:0008340 2 0.942
multicellular organismal aging GO:0010259 3 0.929
regulation of translational initiation GO:0006446 24 0.916
post embryonic development GO:0009791 2 0.782
cytoplasmic translational initiation GO:0002183 6 0.752
oocyte differentiation GO:0009994 2 0.663
rna catabolic process GO:0006401 71 0.598
positive regulation of translation GO:0045727 35 0.588
rna splicing GO:0008380 131 0.538
oocyte development GO:0048599 1 0.512
mitotic cell cycle process GO:1903047 286 0.499
spindle elongation GO:0051231 4 0.494
regulation of mrna metabolic process GO:1903311 53 0.461
mitotic spindle elongation GO:0000022 4 0.458
ribonucleoprotein complex biogenesis GO:0022613 116 0.431
oogenesis GO:0048477 2 0.416
positive regulation of mrna metabolic process GO:1903313 19 0.407
female gamete generation GO:0007292 2 0.369
rna splicing via transesterification reactions GO:0000375 90 0.369
response to abiotic stimulus GO:0009628 336 0.351
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.347
negative regulation of mrna catabolic process GO:1902373 4 0.342
lipid localization GO:0010876 106 0.331
cellular macromolecule catabolic process GO:0044265 380 0.294
intracellular protein transport GO:0006886 270 0.287
aging GO:0007568 66 0.285
mrna catabolic process GO:0006402 56 0.282
positive regulation of developmental process GO:0051094 314 0.269
cellular response to dna damage stimulus GO:0006974 379 0.258
microtubule cytoskeleton organization GO:0000226 176 0.256
mrna metabolic process GO:0016071 175 0.256
nuclear transcribed mrna catabolic process GO:0000956 48 0.247
regulation of mrna processing GO:0050684 48 0.239
mrna processing GO:0006397 133 0.227
anatomical structure formation involved in morphogenesis GO:0048646 284 0.223
stem cell development GO:0048864 69 0.214
memory GO:0007613 3 0.212
primary mirna processing GO:0031053 3 0.208
regulation of mrna splicing via spliceosome GO:0048024 32 0.202
growth GO:0040007 202 0.189
anterior posterior axis specification embryo GO:0008595 2 0.185
adult locomotory behavior GO:0008344 1 0.164
regulation of growth GO:0040008 165 0.162
anterior posterior axis specification GO:0009948 2 0.162
cell development GO:0048468 328 0.161
locomotory behavior GO:0007626 1 0.157
maintenance of location GO:0051235 112 0.155
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.147
cytoplasmic transport GO:0016482 379 0.140
regulation of meiosis GO:0040020 3 0.139
apoptotic signaling pathway GO:0097190 268 0.137
rna processing GO:0006396 255 0.135
regulation of mrna 3 end processing GO:0031440 12 0.134
reproduction GO:0000003 63 0.131
mrna splicing via spliceosome GO:0000398 89 0.122
epithelium development GO:0060429 227 0.120
ras protein signal transduction GO:0007265 73 0.119
cellular component morphogenesis GO:0032989 314 0.118
secondary metabolite biosynthetic process GO:0044550 2 0.115
mitotic nuclear division GO:0007067 119 0.115
mitotic cell cycle GO:0000278 326 0.115
male gamete generation GO:0048232 22 0.099
microtubule based process GO:0007017 210 0.098
membrane organization GO:0061024 292 0.097
endosomal transport GO:0016197 129 0.097
positive regulation of endopeptidase activity GO:0010950 84 0.095
positive regulation of cell activation GO:0050867 81 0.093
cell fate determination GO:0001709 3 0.092
mitotic cell cycle phase transition GO:0044772 162 0.089
regulation of peptidase activity GO:0052547 180 0.087
regionalization GO:0003002 29 0.084
vesicle mediated transport GO:0016192 371 0.084
wnt signaling pathway GO:0016055 156 0.083
endocytosis GO:0006897 159 0.082
positive regulation of developmental growth GO:0048639 16 0.078
heart development GO:0007507 95 0.077
single organism membrane organization GO:0044802 268 0.074
blastoderm segmentation GO:0007350 2 0.071
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.065
tripartite regional subdivision GO:0007351 2 0.062
exocytosis GO:0006887 71 0.060
lipid storage GO:0019915 28 0.059
cellular protein catabolic process GO:0044257 261 0.059
ribonucleoside catabolic process GO:0042454 406 0.057
negative regulation of multi organism process GO:0043901 92 0.057
regulation of homeostatic process GO:0032844 121 0.057
regeneration GO:0031099 4 0.055
cellular hyperosmotic response GO:0071474 4 0.055
circulatory system development GO:0072359 262 0.054
sequestering of metal ion GO:0051238 24 0.053
reproductive process GO:0022414 106 0.053
spermatogenesis GO:0007283 22 0.052
cellular chemical homeostasis GO:0055082 180 0.052
tube development GO:0035295 125 0.052
nucleoside catabolic process GO:0009164 408 0.051
cell morphogenesis involved in differentiation GO:0000904 144 0.051
regulation of cell cycle GO:0051726 393 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.050
single organism cellular localization GO:1902580 332 0.049
neurogenesis GO:0022008 169 0.049
single organism reproductive process GO:0044702 98 0.049
regulation of meiotic cell cycle GO:0051445 4 0.048
multi organism cellular process GO:0044764 156 0.046
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.045
embryo development GO:0009790 123 0.044
dorsal ventral pattern formation GO:0009953 15 0.044
muscle cell differentiation GO:0042692 63 0.043
cell growth GO:0016049 160 0.042
nuclear division GO:0000280 128 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.041
positive regulation of organelle organization GO:0010638 195 0.040
extrinsic apoptotic signaling pathway GO:0097191 119 0.039
positive regulation of cellular component organization GO:0051130 376 0.037
digestive tract morphogenesis GO:0048546 56 0.036
negative regulation of translation GO:0017148 37 0.035
positive regulation of peptidase activity GO:0010952 88 0.034
negative regulation of growth GO:0045926 97 0.034
cell cell signaling GO:0007267 155 0.034
pattern specification process GO:0007389 43 0.034
digestive system development GO:0055123 75 0.034
positive regulation of cell proliferation GO:0008284 301 0.033
nucleoside triphosphate catabolic process GO:0009143 394 0.033
gene silencing GO:0016458 49 0.033
regulation of endopeptidase activity GO:0052548 170 0.033
divalent inorganic cation homeostasis GO:0072507 136 0.032
mrna 3 end processing GO:0031124 24 0.032
axonogenesis GO:0007409 31 0.031
nucleotide catabolic process GO:0009166 408 0.031
metal ion homeostasis GO:0055065 169 0.030
developmental growth GO:0048589 48 0.030
regulation of gene expression epigenetic GO:0040029 73 0.030
cell activation GO:0001775 213 0.030
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.030
microtubule organizing center organization GO:0031023 62 0.029
striated muscle cell differentiation GO:0051146 43 0.028
ribonucleoprotein complex disassembly GO:0032988 7 0.028
biological adhesion GO:0022610 331 0.028
striated muscle myosin thick filament assembly GO:0071688 2 0.028
spermatid differentiation GO:0048515 4 0.028
establishment of vesicle localization GO:0051650 23 0.027
vesicle localization GO:0051648 26 0.027
protein acylation GO:0043543 138 0.027
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.027
negative regulation of rna catabolic process GO:1902369 4 0.026
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.026
protein catabolic process GO:0030163 325 0.026
production of sirna involved in rna interference GO:0030422 3 0.026
neurological system process GO:0050877 163 0.025
regulation of rna splicing GO:0043484 62 0.025
cellular response to arsenic containing substance GO:0071243 4 0.024
positive regulation of growth GO:0045927 58 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
developmental process involved in reproduction GO:0003006 66 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
striated muscle cell development GO:0055002 27 0.023
gastrulation GO:0007369 51 0.023
protein localization to organelle GO:0033365 280 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
muscle structure development GO:0061061 98 0.022
response to osmotic stress GO:0006970 17 0.022
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.022
regulation of proteolysis GO:0030162 293 0.022
cell part morphogenesis GO:0032990 137 0.021
sexual reproduction GO:0019953 37 0.021
regulation of cell migration GO:0030334 289 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
myosin filament assembly GO:0031034 2 0.021
response to heat GO:0009408 21 0.021
neuron differentiation GO:0030182 138 0.021
myosin filament organization GO:0031033 2 0.021
receptor metabolic process GO:0043112 81 0.020
negative regulation of developmental process GO:0051093 247 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
spermatid development GO:0007286 4 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
cellular response to decreased oxygen levels GO:0036294 51 0.020
regulation of ion homeostasis GO:2000021 73 0.019
positive regulation of translational initiation GO:0045948 7 0.019
alternative mrna splicing via spliceosome GO:0000380 27 0.019
regulation of cysteine type endopeptidase activity GO:2000116 127 0.019
neural crest cell development GO:0014032 3 0.019
negative regulation of viral process GO:0048525 66 0.019
cellular response to oxygen levels GO:0071453 55 0.019
interspecies interaction between organisms GO:0044419 156 0.019
regulation of nuclear division GO:0051783 65 0.019
notch receptor processing GO:0007220 2 0.019
autophagy GO:0006914 88 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
secretion by cell GO:0032940 226 0.018
regulation of cell activation GO:0050865 125 0.018
multicellular organism reproduction GO:0032504 42 0.018
segmentation GO:0035282 4 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
response to nitrogen compound GO:1901698 184 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
peptidyl serine modification GO:0018209 106 0.017
cellular response to hypoxia GO:0071456 51 0.017
antigen processing and presentation GO:0019882 33 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
trophectodermal cell differentiation GO:0001829 3 0.017
gene silencing by rna GO:0031047 26 0.017
7 methylguanosine rna capping GO:0009452 9 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
spindle organization GO:0007051 53 0.016
response to salt stress GO:0009651 3 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.016
regulation of developmental growth GO:0048638 30 0.016
rna interference GO:0016246 4 0.016
mitotic spindle organization GO:0007052 27 0.016
chordate embryonic development GO:0043009 34 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.016
multi organism reproductive process GO:0044703 54 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
antigen processing and presentation via mhc class ib GO:0002475 3 0.016
regulation of vesicle mediated transport GO:0060627 130 0.015
golgi vesicle transport GO:0048193 80 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cation homeostasis GO:0055080 189 0.015
axis specification GO:0009798 12 0.015
organelle fission GO:0048285 149 0.015
positive regulation of mrna processing GO:0050685 17 0.015
regulation of cell growth GO:0001558 135 0.015
response to oxygen levels GO:0070482 100 0.015
regulation of cell differentiation GO:0045595 393 0.015
multicellular organismal reproductive process GO:0048609 40 0.015
tube morphogenesis GO:0035239 95 0.014
dephosphorylation GO:0016311 209 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
protein targeting GO:0006605 187 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.014
atp metabolic process GO:0046034 176 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
cytoplasmic translation GO:0002181 8 0.014
hemopoiesis GO:0030097 180 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
nervous system development GO:0007399 293 0.013
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.013
viral process GO:0016032 146 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
nuclear export GO:0051168 69 0.013
embryonic morphogenesis GO:0048598 85 0.013
amine metabolic process GO:0009308 44 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
protein localization to membrane GO:0072657 160 0.013
positive regulation of cell cycle process GO:0090068 106 0.012
cellular component disassembly GO:0022411 92 0.012
retrograde transport endosome to golgi GO:0042147 45 0.012
receptor mediated endocytosis GO:0006898 84 0.012
response to temperature stimulus GO:0009266 22 0.012
cellular homeostasis GO:0019725 196 0.012
cell cycle phase transition GO:0044770 173 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
muscle cell development GO:0055001 29 0.012
cellular response to metal ion GO:0071248 43 0.012
developmental maturation GO:0021700 28 0.012
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.012
eye pigmentation GO:0048069 1 0.012
negative regulation of ras protein signal transduction GO:0046580 11 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
positive regulation of cell migration GO:0030335 172 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
long term memory GO:0007616 2 0.012
regulation of endocytosis GO:0030100 72 0.011
protein maturation GO:0051604 233 0.011
stem cell differentiation GO:0048863 93 0.011
anterograde axon cargo transport GO:0008089 1 0.011
mitochondrial transport GO:0006839 60 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
regulation of cell cycle process GO:0010564 266 0.011
cell morphogenesis GO:0000902 296 0.011
central nervous system development GO:0007417 123 0.011
digestive tract development GO:0048565 75 0.011
response to decreased oxygen levels GO:0036293 96 0.011
female pregnancy GO:0007565 17 0.011
ncrna metabolic process GO:0034660 108 0.011
chromatin organization GO:0006325 351 0.011
establishment of protein localization to mitochondrion GO:0072655 22 0.011
reproductive system development GO:0061458 56 0.011
atp catabolic process GO:0006200 157 0.011
negative regulation of cell growth GO:0030308 83 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
viral life cycle GO:0019058 132 0.010
cell division GO:0051301 168 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
synaptic transmission GO:0007268 61 0.010
embryo development ending in birth or egg hatching GO:0009792 34 0.010

EIF4G1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.093
nervous system disease DOID:863 431 0.093
neurodegenerative disease DOID:1289 102 0.093
developmental disorder of mental health DOID:0060037 29 0.026
disease of mental health DOID:150 70 0.026
musculoskeletal system disease DOID:17 223 0.023
disease of cellular proliferation DOID:14566 174 0.017
cancer DOID:162 167 0.017
pervasive developmental disorder DOID:0060040 10 0.013
muscular disease DOID:0080000 114 0.012
myopathy DOID:423 104 0.012
muscle tissue disease DOID:66 113 0.012
glucose metabolism disease DOID:4194 32 0.011
disease of metabolism DOID:0014667 295 0.011
carbohydrate metabolism disease DOID:0050013 32 0.011
acquired metabolic disease DOID:0060158 58 0.011
parkinson s disease DOID:14330 18 0.002
synucleinopathy DOID:0050890 22 0.002