|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
1.000
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
5 |
0.985
|
Human Mouse |
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.955
|
Human |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.951
|
Mouse |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.939
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.934
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.930
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.913
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.868
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.865
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.862
|
Human Zebrafish |
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.823
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.823
|
Human Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.821
|
Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.802
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.779
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.768
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.765
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.763
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.758
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.747
|
Human |
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.726
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.716
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.707
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.694
|
Mouse |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.680
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.672
|
Fly |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.669
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.635
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.635
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.622
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.620
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.617
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.616
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.616
|
Mouse |
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.613
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.613
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.608
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.570
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.564
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.561
|
Fly |
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.558
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.551
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.543
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.543
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.538
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.530
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.526
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.514
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.512
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.509
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.504
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.499
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.492
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.489
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.482
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.480
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.478
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.476
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.473
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.468
|
|
|
|
positive regulation of hormone metabolic process
|
GO:0032352 |
6 |
0.461
|
Human |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.456
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.453
|
Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.452
|
Zebrafish |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.452
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.449
|
Worm |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.448
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.445
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.442
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.439
|
Human Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.437
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.437
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.428
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.425
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.422
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.421
|
|
|
|
oxygen homeostasis
|
GO:0032364 |
4 |
0.417
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.413
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.408
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.408
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.406
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.405
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.398
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.396
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.396
|
Human Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.395
|
Human Worm |
|
|
camp catabolic process
|
GO:0006198 |
8 |
0.394
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.393
|
|
|
|
system process
|
GO:0003008 |
349 |
0.389
|
Mouse |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.388
|
Fly |
|
|
response to insulin
|
GO:0032868 |
45 |
0.373
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.372
|
|
|
|
response to redox state
|
GO:0051775 |
7 |
0.369
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.368
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.368
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.366
|
Mouse Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.360
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.359
|
Human Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.356
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
10 |
0.353
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.348
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.340
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.331
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061418 |
7 |
0.330
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.326
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.324
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.318
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.318
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.317
|
Zebrafish |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.314
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.312
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.312
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.310
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.301
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.296
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.293
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.292
|
Fly |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.290
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.287
|
Fly |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.287
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.284
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.284
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.282
|
|
|
|
gas homeostasis
|
GO:0033483 |
4 |
0.277
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.271
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.268
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.268
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.267
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.266
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.259
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.258
|
Human Mouse |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.257
|
Mouse |
|
|
protein hydroxylation
|
GO:0018126 |
9 |
0.254
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.252
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.242
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.239
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.233
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.232
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.232
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.231
|
Human Mouse |
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.228
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.228
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.227
|
Human Zebrafish |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.226
|
Worm |
|
|
lipid localization
|
GO:0010876 |
106 |
0.221
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.220
|
Human Zebrafish |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.218
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.216
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.214
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.209
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.209
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.207
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.205
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.202
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.200
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.197
|
|
|
|
4 hydroxyproline metabolic process
|
GO:0019471 |
5 |
0.194
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.194
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.192
|
Mouse |
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.192
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.192
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.191
|
Mouse Fly |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.189
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.188
|
|
|
|
placenta development
|
GO:0001890 |
10 |
0.187
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.182
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.181
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.181
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.180
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.176
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.174
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.173
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.172
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.172
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.172
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.170
|
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.168
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.166
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.164
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.164
|
Mouse |
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.163
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.162
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.161
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.160
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.159
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.158
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.157
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.155
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.153
|
Human Zebrafish |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.153
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.152
|
Worm |
|
|
lipid transport
|
GO:0006869 |
90 |
0.151
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.151
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.151
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.149
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.148
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.148
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.148
|
Mouse Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.143
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.143
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.143
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.142
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.141
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.141
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.139
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.138
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.137
|
Mouse |
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.137
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.136
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.136
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.135
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.134
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.132
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.131
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.130
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.127
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.127
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.127
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.127
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.126
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.124
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.124
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.123
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.123
|
Zebrafish |
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.122
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.122
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.122
|
|
|
|
head development
|
GO:0060322 |
108 |
0.122
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.121
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.121
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.121
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.120
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.120
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.119
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.119
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.119
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.118
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.117
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.117
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.116
|
Zebrafish |
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.116
|
Mouse |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.116
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.115
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.115
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.114
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.112
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.112
|
Worm |
|
|
peptidyl proline modification
|
GO:0018208 |
15 |
0.111
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.110
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.109
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.107
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.105
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.105
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.105
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.105
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.104
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.103
|
Fly |
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.103
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.103
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.102
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.102
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.101
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.101
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.100
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.099
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.098
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.098
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.096
|
|
|
|
negative regulation of nucleotide catabolic process
|
GO:0030812 |
16 |
0.096
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.096
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.096
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.095
|
Human Zebrafish |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.095
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.095
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.094
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.093
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.093
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.092
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.092
|
|
|
|
negative regulation of thymocyte apoptotic process
|
GO:0070244 |
1 |
0.091
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.090
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.090
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.088
|
Mouse |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.088
|
Fly |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.088
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.087
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.086
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.086
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.086
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.086
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.086
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.086
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.086
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.085
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.084
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.084
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.084
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.083
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.083
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.083
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.083
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.082
|
|
|
|
growth
|
GO:0040007 |
202 |
0.082
|
Fly |
|
|
aging
|
GO:0007568 |
66 |
0.082
|
Worm |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.082
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.082
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.081
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.081
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.080
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.080
|
|
|
|
smooth muscle cell differentiation
|
GO:0051145 |
8 |
0.080
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.080
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.080
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.080
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.079
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.079
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.079
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.078
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.078
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.078
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.077
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.077
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.077
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.077
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.077
|
Worm |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.077
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.077
|
Mouse |
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.077
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.075
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.075
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.075
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.075
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.074
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.073
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.073
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.073
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.072
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.071
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.071
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.070
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.070
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.070
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.070
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.069
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.068
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.068
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.068
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.068
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.068
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.067
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.067
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.067
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.066
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.066
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.065
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.065
|
Human Worm |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.065
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.065
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.064
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.064
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.063
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.063
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.062
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.062
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.062
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.062
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.061
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.061
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.061
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.061
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.061
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.060
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.060
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.059
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.059
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.059
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.058
|
Worm |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.058
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.058
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.058
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.058
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.058
|
Human |
|
|
renal tubule development
|
GO:0061326 |
19 |
0.058
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.057
|
Fly |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.057
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.057
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.057
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.057
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.057
|
Fly |
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.056
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.056
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.056
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.056
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.055
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.055
|
Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.055
|
Mouse |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.055
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.054
|
|
|
|
glomerulus development
|
GO:0032835 |
15 |
0.054
|
|
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.053
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.053
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.053
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.053
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.053
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.052
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.052
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.052
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.052
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.052
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.052
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.051
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.051
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.051
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.051
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.051
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.051
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.051
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.051
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.050
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.050
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.050
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.049
|
Human |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.049
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.049
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.049
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.049
|
|
|
|
memory
|
GO:0007613 |
3 |
0.049
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.049
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.049
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.048
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.048
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.048
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.048
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.048
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.047
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.047
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.047
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.047
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.047
|
|
|
|
cyclic nucleotide catabolic process
|
GO:0009214 |
9 |
0.047
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.046
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.046
|
Mouse |
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.046
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.045
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.045
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.045
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.045
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.044
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.044
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.044
|
Fly |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.044
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.044
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.044
|
Fly |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.043
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.043
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.043
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.043
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.043
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.043
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.043
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.043
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.042
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.042
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.042
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.042
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.042
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.042
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.042
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.041
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.041
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.041
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.041
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.041
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.041
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.041
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.041
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.041
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.040
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.040
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.040
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.040
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.040
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.040
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.040
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.039
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.039
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.039
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.039
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.038
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.038
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.038
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.038
|
|
