|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
1.000
|
Human |
|
|
cranial nerve development
|
GO:0021545 |
4 |
1.000
|
Zebrafish |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
1.000
|
Human |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
1.000
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
1.000
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
1.000
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
Human |
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
1.000
|
Human |
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
1.000
|
Human |
|
|
nerve development
|
GO:0021675 |
4 |
1.000
|
Zebrafish |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
1.000
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
1.000
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
1.000
|
Human |
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
1.000
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
1.000
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
1.000
|
Human |
|
|
neural crest cell migration
|
GO:0001755 |
2 |
1.000
|
Zebrafish |
|
|
associative learning
|
GO:0008306 |
1 |
1.000
|
Fly |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
1.000
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
1.000
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
1.000
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
1.000
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
1.000
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
1.000
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
1.000
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
1.000
|
|
|
|
schwann cell development
|
GO:0014044 |
1 |
1.000
|
Zebrafish |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
1.000
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
1.000
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
1.000
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
1.000
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
1.000
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
1.000
|
|
|
|
immune system development
|
GO:0002520 |
195 |
1.000
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
1.000
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
1.000
|
Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
1.000
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
1.000
|
Zebrafish Mouse Rat Fly |
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
1.000
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
1.000
|
Mouse |
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
1.000
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
1.000
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
1.000
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
1.000
|
Human |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
1.000
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
1.000
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
1.000
|
Mouse |
|
|
startle response
|
GO:0001964 |
3 |
1.000
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.999
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.999
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.999
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.999
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.999
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.999
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.999
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.999
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.999
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.999
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.999
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.999
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.999
|
Worm |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.999
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.999
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.999
|
Mouse Fly |
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.999
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.999
|
Human |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.999
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.999
|
Human Rat Fly |
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.999
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.999
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.999
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.999
|
Fly |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.999
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.999
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.999
|
Zebrafish Mouse Fly |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.999
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.999
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.999
|
Fly |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.999
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.998
|
Rat |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.998
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.998
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.998
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.998
|
Zebrafish Fly |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.998
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.998
|
Zebrafish Mouse Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.998
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.997
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.997
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.997
|
Human |
|
|
glial cell development
|
GO:0021782 |
7 |
0.997
|
Zebrafish |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.997
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.997
|
Human |
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.997
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.997
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.996
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.996
|
Zebrafish |
|
|
cell activation
|
GO:0001775 |
213 |
0.996
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.996
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.996
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.996
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.996
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.995
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.995
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.995
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.995
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.995
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.995
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.995
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.995
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.994
|
Human Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.994
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.994
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.994
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.994
|
Zebrafish Mouse Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.994
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.993
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.993
|
Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.993
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.993
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.993
|
Zebrafish Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.993
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.993
|
Human Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.993
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.992
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.992
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.991
|
Zebrafish Mouse Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.991
|
Human |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.991
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.991
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.991
|
Rat |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.990
|
Fly |
|
|
tissue migration
|
GO:0090130 |
119 |
0.990
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.990
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.990
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.990
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.990
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.990
|
Human |
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.990
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.989
|
Mouse |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.989
|
Mouse |
|
|
taxis
|
GO:0042330 |
157 |
0.989
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.988
|
Mouse |
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.987
|
Zebrafish |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.987
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.986
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.986
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.986
|
Mouse |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.985
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.985
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.985
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.985
|
Human Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.985
|
Zebrafish Mouse Rat Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.984
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.984
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.984
|
Zebrafish Mouse |
|
|
gland development
|
GO:0048732 |
48 |
0.983
|
Human Rat Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.983
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.983
|
Mouse |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.983
|
Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.983
|
Zebrafish Mouse Rat Fly |
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
11 |
0.982
|
Human |
|
|
response to insulin
|
GO:0032868 |
45 |
0.982
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.982
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.981
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.981
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.981
|
Mouse |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.981
|
Zebrafish Mouse Fly |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.980
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.980
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.977
|
Mouse |
|
|
positive regulation of transcription from rna polymerase i promoter
|
GO:0045943 |
6 |
0.977
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.976
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.976
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.976
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.976
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.974
|
Zebrafish Mouse |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.974
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.973
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.973
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.972
|
Human |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.971
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.970
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.970
|
Human Rat Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.969
|
Zebrafish Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.968
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.968
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.968
|
Zebrafish Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.967
|
Mouse |
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.967
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.965
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.965
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.964
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.964
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.964
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.963
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.963
|
Mouse Rat |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.962
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.962
|
Human |
|
|
tongue development
|
GO:0043586 |
1 |
0.961
|
Rat |
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
13 |
0.960
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.960
|
Zebrafish Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.957
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.956
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.956
|
Fly |
|
|
lactation
|
GO:0007595 |
3 |
0.956
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.955
|
Mouse |
|
|
peptidyl tyrosine autophosphorylation
|
GO:0038083 |
5 |
0.954
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.954
|
Mouse |
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.952
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.951
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.951
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.950
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.950
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.950
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.949
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.948
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.948
|
|
|
|
positive regulation of transcription from rna polymerase iii promoter
|
GO:0045945 |
10 |
0.948
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.948
|
Human |
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.947
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.945
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.943
|
Mouse |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.942
|
Mouse Rat |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.942
|
Zebrafish Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.939
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.939
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.939
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.937
|
Human Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.937
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.937
|
Human |
|
|
stem cell division
|
GO:0017145 |
2 |
0.935
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.935
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.933
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.931
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.929
|
Fly |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.928
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.926
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.926
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.925
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.924
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.922
|
Worm |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.920
|
Mouse |
|
|
regulation of transcription from rna polymerase i promoter
|
GO:0006356 |
10 |
0.918
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.917
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.916
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.916
|
|
|
|
cellular response to estrogen stimulus
|
GO:0071391 |
16 |
0.914
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.914
|
Human Fly |
|
|
heart process
|
GO:0003015 |
62 |
0.913
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.907
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.906
|
Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.906
|
Mouse |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.905
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.904
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.903
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.900
|
Fly |
|
|
coagulation
|
GO:0050817 |
78 |
0.898
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.896
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.893
|
Mouse |
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.893
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.892
|
Fly |
|
|
response to uv a
|
GO:0070141 |
6 |
0.890
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.889
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.887
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.884
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.883
|
Human |
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.883
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.882
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.879
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.879
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.877
|
Human Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.874
|
Human Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.873
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.872
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.871
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.870
|
Human |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.870
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.867
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.866
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.861
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.861
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.860
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.858
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.857
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
13 |
0.853
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.850
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.848
|
Rat |
|
|
exocytosis
|
GO:0006887 |
71 |
0.847
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.847
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.845
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.845
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.843
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.840
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.837
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.834
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.833
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
159 |
0.829
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.825
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.824
|
Rat |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.823
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.821
|
Human |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.819
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.818
|
Mouse |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.817
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.816
|
Human |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.815
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.815
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.814
|
Human |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.811
|
Mouse |
|
|
phosphatidylinositol biosynthetic process
|
GO:0006661 |
25 |
0.811
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.810
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.810
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.809
|
Human |
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.806
|
Rat |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.806
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.801
|
Human Rat Fly |
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.799
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.798
|
Worm Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.797
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.797
|
Human |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.794
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.794
|
Mouse |
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.794
|
Human |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.793
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
5 |
0.792
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.792
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.791
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.788
|
Rat |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.787
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.784
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.782
|
|
|
|
transcription from rna polymerase i promoter
|
GO:0006360 |
11 |
0.781
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.772
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.769
|
Human Rat Fly |
|
|
fc receptor signaling pathway
|
GO:0038093 |
2 |
0.769
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.765
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.765
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.759
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.753
|
Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.747
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.744
|
Mouse Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.743
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.742
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.739
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.738
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.737
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.737
|
Zebrafish Fly |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.734
|
Zebrafish |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.727
|
Human Fly |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.726
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.724
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.719
|
Mouse |
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.717
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.713
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.713
|
Zebrafish Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.708
|
Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.707
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.707
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.706
|
Human |
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.704
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.701
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.700
|
Zebrafish Mouse |
|
|
response to drug
|
GO:0042493 |
81 |
0.699
|
Rat |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.698
|
Human |
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.695
|
Human |
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.694
|
Rat |
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.691
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.691
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.690
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.689
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.684
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.684
|
Mouse |
|
|
secretion by tissue
|
GO:0032941 |
9 |
0.683
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.681
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.680
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.679
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.678
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.674
|
Fly |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.672
|
Human |
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.671
|
|
|
|
kit signaling pathway
|
GO:0038109 |
1 |
0.671
|
|
|
|
translation
|
GO:0006412 |
132 |
0.656
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.655
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.653
|
Zebrafish |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.652
|
Mouse |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.650
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.643
|
Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.642
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.641
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.641
|
Human |
|
|
mammary gland development
|
GO:0030879 |
17 |
0.640
|
Human Rat |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.638
|
Human Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.635
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.633
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.633
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.631
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.628
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.626
|
Human |
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.623
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.616
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.614
|
Mouse |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.613
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.612
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.611
|
Fly |
|
|
exocrine system development
|
GO:0035272 |
7 |
0.607
|
Fly |
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.605
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.605
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.604
|
|
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.602
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.602
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.602
|
Mouse |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.601
|
Human |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.600
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.599
|
Human |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.594
|
Human |
|
|
cell growth
|
GO:0016049 |
160 |
0.593
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.586
|
Mouse |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.586
|
|
|
|
response to macrophage colony stimulating factor
|
GO:0036005 |
4 |
0.586
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.582
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.576
|
|
|
|
ciliary neurotrophic factor mediated signaling pathway
|
GO:0070120 |
5 |
0.570
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.566
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.566
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.564
|
Human |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.557
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.556
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.555
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.555
|
Worm |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.555
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.552
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.549
|
Human |
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.548
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.545
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.541
|
Zebrafish |
|
|
neurological system process
|
GO:0050877 |
163 |
0.540
|
Zebrafish Mouse Fly |
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
10 |
0.532
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.531
|
Human |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.524
|
Human |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.522
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.519
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.515
|
Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.514
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.506
|
Fly |
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.502
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.498
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.496
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.494
|
Human |
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.492
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.490
|
Fly |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.487
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.486
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.484
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.481
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.480
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.479
|
Human Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.478
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.477
|
Fly |
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.473
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.464
|
Mouse |
|
|
neural crest cell differentiation
|
GO:0014033 |
5 |
0.463
|
Zebrafish |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.462
|
Human |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.461
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.457
|
Human |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.456
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.455
|
|
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.453
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.452
|
Human |
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.452
|
Human |
|
|
surfactant homeostasis
|
GO:0043129 |
3 |
0.449
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.447
|
Mouse |
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.446
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.446
|
Worm Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.441
|
Human Rat |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.440
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.440
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.440
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.440
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.434
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.432
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.431
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.430
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.424
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.423
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.420
|
|
