|
|
intermediate filament based process
|
GO:0045103 |
17 |
0.997
|
Worm |
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.978
|
Worm |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.951
|
Human Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.936
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.928
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.928
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
2 |
0.904
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.902
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.901
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.901
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.900
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.897
|
Worm |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.894
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.876
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.870
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.866
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.850
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.837
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.804
|
Human Worm |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.801
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.794
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.794
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.772
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.770
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.765
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.760
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.757
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.747
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.724
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.705
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.702
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.688
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.684
|
Worm |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.675
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.673
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.671
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.669
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.665
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.661
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.659
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.651
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.642
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.637
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.632
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.629
|
|
|
|
system process
|
GO:0003008 |
349 |
0.607
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.597
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.585
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.580
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.576
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.568
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.549
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.541
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.536
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.527
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.526
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.521
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.521
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.521
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.513
|
Worm |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.509
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.504
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.503
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.500
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.493
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.484
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.480
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.477
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.477
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.473
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.471
|
Human |
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.467
|
|
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.466
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.463
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.461
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.460
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.455
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.447
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.444
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.438
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.435
|
Human |
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.434
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.423
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.422
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.418
|
Human Worm |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.418
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.409
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.408
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.394
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.389
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.382
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.381
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.375
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.367
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.367
|
Worm |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.363
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.358
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.348
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.347
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.343
|
Human Worm |
|
|
nervous system development
|
GO:0007399 |
293 |
0.339
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.338
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.337
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.328
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.328
|
Worm |
|
|
tube development
|
GO:0035295 |
125 |
0.327
|
Human Worm |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.327
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.326
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.326
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.325
|
Human |
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.321
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.321
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.316
|
Human |
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.316
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.315
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.314
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.311
|
Human |
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.307
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.305
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.304
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.299
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.298
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.297
|
Human |
|
|
skin development
|
GO:0043588 |
76 |
0.294
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.293
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.292
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.286
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.284
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.283
|
Worm |
|
|
cell division
|
GO:0051301 |
168 |
0.282
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.278
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.274
|
Human |
|
|
heart development
|
GO:0007507 |
95 |
0.272
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.267
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.267
|
Mouse |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.265
|
Worm |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.265
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.263
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.258
|
|
|
|
desmosome assembly
|
GO:0002159 |
4 |
0.256
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.255
|
Human |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.255
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.252
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.246
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.246
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.244
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.243
|
Human |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.243
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.242
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.241
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.240
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.232
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.231
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.229
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.228
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.227
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.227
|
Worm |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.225
|
Worm |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.222
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.221
|
Human |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.217
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.215
|
Human |
|
|
nuclear import
|
GO:0051170 |
106 |
0.214
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.213
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.211
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.210
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.208
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.205
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.203
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.202
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.202
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.202
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.201
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.201
|
Human Worm |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.199
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.198
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.195
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.195
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.195
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.194
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.194
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.194
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.194
|
Human Worm |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.192
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.190
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.189
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.188
|
Worm |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.188
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.188
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.188
|
Human |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.187
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.181
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.181
|
Human |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.180
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.180
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.176
|
|
|
|
intermediate filament organization
|
GO:0045109 |
10 |
0.176
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.176
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.174
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.172
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.172
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.172
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.171
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.171
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.171
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.168
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.166
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.165
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.163
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.161
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.157
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.156
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.156
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.155
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.153
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.153
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.153
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.153
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.151
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.149
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.144
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.144
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.143
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.143
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.143
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.142
|
Human |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.142
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.140
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.138
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.138
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.137
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.137
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.136
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.134
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.134
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.133
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.133
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.132
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.129
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.128
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.128
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.128
|
|
|
|
growth
|
GO:0040007 |
202 |
0.127
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.126
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.126
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.125
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.123
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.123
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.123
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.123
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.122
|
Human Worm |
|
|
gland development
|
GO:0048732 |
48 |
0.121
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.120
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.120
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.119
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.119
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.119
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.119
|
|
|
|
muscle hypertrophy in response to stress
|
GO:0003299 |
4 |
0.119
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.118
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.117
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.116
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.116
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.115
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.115
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.114
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.112
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.112
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.112
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.112
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.111
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.111
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.110
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.110
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.108
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.107
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.107
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.107
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.107
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.107
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.106
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.105
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.105
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.104
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.103
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.103
|
Worm |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.101
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.101
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.101
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.100
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.100
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.098
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.098
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.098
|
Human |
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.097
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.095
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.095
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.094
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.094
|
Human |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.093
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.093
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.092
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.092
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.091
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.090
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.090
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.090
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.089
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.089
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.088
|
Human |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.087
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.086
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.085
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.084
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.084
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.084
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.083
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.082
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.082
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.082
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.081
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.081
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.081
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.080
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.080
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.080
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.080
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.080
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.079
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.078
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.078
|
|
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.078
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.077
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.077
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.077
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.077
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.077
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.076
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.076
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.076
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.075
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.075
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.075
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.075
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.073
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.073
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.073
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.073
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.072
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.072
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.072
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.071
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.071
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.071
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.071
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.071
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.070
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.070
|
Worm |
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.069
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.069
|
Human Worm |
|
|
membrane organization
|
GO:0061024 |
292 |
0.068
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.068
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.067
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.067
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.067
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.066
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.066
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.066
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.066
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.065
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.065
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.065
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.065
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.064
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.064
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.064
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.063
|
|
|
|
head development
|
GO:0060322 |
108 |
0.063
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.062
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.062
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.061
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.060
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.060
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.060
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.059
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.059
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.059
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.059
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.058
|
Human |
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.058
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.058
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.058
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.058
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.057
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.056
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.056
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.056
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.056
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.056
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.055
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.055
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.055
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.055
|
|
|
|
cell communication involved in cardiac conduction
|
GO:0086065 |
18 |
0.055
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.054
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.054
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.054
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.053
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.053
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.052
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.052
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.052
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.052
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.052
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.052
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.052
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.052
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.051
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.051
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.051
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.051
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.050
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.050
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.050
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.050
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.049
|
Worm |
|
|
pharynx development
|
GO:0060465 |
1 |
0.048
|
Worm |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.048
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.048
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.048
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.047
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.047
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.047
|
Human |
|
|
dendrite development
|
GO:0016358 |
24 |
0.047
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.046
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.045
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.045
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.045
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.045
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.044
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.044
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.044
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.043
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.043
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.043
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.043
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.043
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.043
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.042
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.042
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.042
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.042
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.042
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.042
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.041
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.041
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.041
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.041
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.041
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.041
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.041
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.041
|
Worm |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.041
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.040
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.040
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.040
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.040
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.040
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.040
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.039
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.039
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.039
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.039
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.039
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.039
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.039
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.039
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.038
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.038
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.038
|
Worm |
|
|
axon development
|
GO:0061564 |
34 |
0.038
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.037
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.037
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.037
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.036
|
|
