|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
1.000
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.999
|
|
|
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
0.998
|
|
|
|
mating
|
GO:0007618 |
1 |
0.997
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.992
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.990
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.977
|
Mouse Worm |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.963
|
Mouse Fly |
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.961
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.956
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.956
|
Rat |
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.938
|
Fly |
|
|
startle response
|
GO:0001964 |
3 |
0.933
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.931
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.915
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.911
|
Mouse Fly |
|
|
growth
|
GO:0040007 |
202 |
0.911
|
Human Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.905
|
Human Rat Fly |
|
|
associative learning
|
GO:0008306 |
1 |
0.890
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.879
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.878
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.856
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.855
|
Worm Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.849
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.847
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.829
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.824
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.821
|
Mouse Rat Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.814
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.809
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.808
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.799
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.794
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.790
|
Human Fly |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.786
|
|
|
|
system process
|
GO:0003008 |
349 |
0.779
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.772
|
Fly |
|
|
action potential
|
GO:0001508 |
34 |
0.768
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.739
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.732
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.729
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.727
|
Mouse Fly |
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.722
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.721
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.718
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.706
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.684
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.683
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.676
|
Mouse Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.665
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.665
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.660
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.659
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.648
|
Worm Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.641
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
15 |
0.621
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.621
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.619
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.618
|
Human Fly |
|
|
behavior
|
GO:0007610 |
112 |
0.614
|
Fly |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.612
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.598
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.585
|
Mouse Fly |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.584
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.583
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.566
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.557
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.534
|
|
|
|
directional locomotion
|
GO:0033058 |
1 |
0.518
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.517
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.515
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.508
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.508
|
Human Fly |
|
|
sleep
|
GO:0030431 |
2 |
0.497
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.495
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.492
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.491
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.476
|
|
|
|
vocalization behavior
|
GO:0071625 |
11 |
0.474
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.474
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.466
|
Human Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.461
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.458
|
Rat |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.457
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.456
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.447
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.445
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
1 |
0.439
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.437
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.429
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.428
|
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.427
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.425
|
Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.424
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.413
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.396
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.391
|
Human Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.391
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.387
|
Human Mouse Rat |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.384
|
Fly |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.379
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.357
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.356
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.352
|
Human |
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.349
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.339
|
Mouse |
|
|
neuromuscular process controlling balance
|
GO:0050885 |
7 |
0.339
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.336
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.334
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.334
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.323
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.320
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.317
|
Fly |
|
|
memory
|
GO:0007613 |
3 |
0.312
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.302
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.300
|
Fly |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.299
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.294
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.293
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.293
|
Rat Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.286
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.286
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.283
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.280
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.280
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.277
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.275
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.275
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.274
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.267
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.265
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.261
|
Mouse Rat |
|
|
taxis
|
GO:0042330 |
157 |
0.257
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.255
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.254
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.254
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.249
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.248
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.248
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.239
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.238
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.238
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.238
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.233
|
Human Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.233
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.232
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
2 |
0.230
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.229
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.222
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.220
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.219
|
Worm Fly |
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.218
|
Mouse |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.214
|
Fly |
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.213
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.213
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.212
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.211
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.211
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.209
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.209
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.207
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.205
|
Human Rat |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.205
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.203
|
Mouse |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.203
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.202
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.200
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.199
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.196
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.193
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.191
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.187
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.186
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.184
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.180
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.180
|
Human Mouse Rat |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.179
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.178
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.177
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.177
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.175
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.174
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.173
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.170
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.169
|
Human Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.167
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.166
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.165
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.164
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.162
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.161
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.160
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.160
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.158
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.158
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.157
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.156
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.154
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.149
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.145
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.145
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.145
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.144
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.144
|
|
|
|
potassium ion export
|
GO:0071435 |
9 |
0.143
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.142
|
Mouse Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.142
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.141
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.141
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.140
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.139
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.135
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.132
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.132
|
Rat Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.131
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.129
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.129
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.128
|
Fly |
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.127
|
|
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.126
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.126
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.125
|
Mouse |
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.125
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.122
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.122
|
Human |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.122
|
Fly |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.121
|
Rat |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.121
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.121
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.120
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.120
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.120
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.119
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.119
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.119
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.118
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.117
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.117
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.115
|
Mouse |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.114
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.113
|
Human |
|
|
axon development
|
GO:0061564 |
34 |
0.111
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.111
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.111
|
Human Fly |
|
|
tight junction assembly
|
GO:0070830 |
14 |
0.111
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.111
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.110
|
Human Rat |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.109
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.109
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.108
|
|
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
20 |
0.107
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.107
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.107
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.106
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.106
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.106
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.105
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.105
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.104
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.100
|
Mouse |
|
|
response to ethanol
|
GO:0045471 |
11 |
0.100
|
Fly |
|
|
response to peptide
|
GO:1901652 |
65 |
0.098
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.097
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.096
|
Mouse |
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.096
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.095
|
Fly |
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.095
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.095
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.094
|
Human Fly |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.094
|
Human Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.092
|
Human |
|
|
neuron cell cell adhesion
|
GO:0007158 |
1 |
0.091
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.091
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.090
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.090
|
Mouse Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.088
|
Mouse Rat |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.088
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.087
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.087
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.086
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.086
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.085
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.085
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.084
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.084
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.084
|
Human |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.084
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.084
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.083
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.083
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.083
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.082
|
Fly |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.082
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.081
|
Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.081
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.080
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.078
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.077
|
Human |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.077
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.076
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.076
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.076
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.075
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.074
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.074
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.073
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.073
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.073
|
Worm |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.073
|
Human Fly |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.073
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.072
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.071
|
Human Rat |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.071
|
Mouse |
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.071
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.069
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.069
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.069
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.068
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.068
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.068
|
Fly |
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.068
|
Human |
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.068
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.067
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.067
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.067
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.067
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.067
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.066
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.066
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.066
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.066
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.065
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.065
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.064
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.064
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.063
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.063
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.063
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.062
|
Mouse Fly |
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.062
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.062
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.062
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.062
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.061
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.061
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.061
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.061
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.061
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.061
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.061
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.061
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.060
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.060
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.060
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.059
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.059
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.058
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.058
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.057
|
Human Rat |
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.057
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.057
|
Fly |
|
|
schwann cell development
|
GO:0014044 |
1 |
0.057
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.056
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.056
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.056
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.055
|
Mouse Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.055
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.055
|
Fly |
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.055
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.054
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.054
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.053
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.053
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.053
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.053
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.053
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.052
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.052
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.052
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.052
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.052
|
Human Rat Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.052
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.051
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.051
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.051
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.050
|
Fly |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.050
|
|
|
|
neuromuscular process
|
GO:0050905 |
15 |
0.049
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.049
|
|
|
|
neuronal ion channel clustering
|
GO:0045161 |
2 |
0.048
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.048
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.047
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.047
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.047
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.047
|
|
|
|
head development
|
GO:0060322 |
108 |
0.047
|
Mouse Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.046
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.046
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.046
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.045
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.045
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.045
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.044
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.043
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.043
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.043
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.043
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.043
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.043
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.043
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.043
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.043
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.043
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.043
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.043
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.043
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.042
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.042
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.042
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.042
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.042
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.041
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.041
|
Fly |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.041
|
Human |
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.041
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.041
|
Human Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.040
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.040
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.040
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.040
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
Fly |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.040
|
Worm Fly |
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.040
|
|
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
0.039
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.039
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.039
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.039
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.039
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.039
|
Mouse |
|
|
receptor localization to synapse
|
GO:0097120 |
1 |
0.039
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.039
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.038
|
|
|
|
negative regulation of receptor mediated endocytosis
|
GO:0048261 |
6 |
0.038
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.038
|
Fly |
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.038
|
Human |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.038
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.038
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.037
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.037
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.037
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.037
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.037
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.037
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.037
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.037
|
Human |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.036
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.036
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.036
|
Fly |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.036
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.036
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.036
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.036
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.036
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.036
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.035
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.035
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.035
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.035
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.034
|
Human |
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.034
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.034
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.034
|
Human |
|
|
dendrite development
|
GO:0016358 |
24 |
0.034
|
|
|
|
multi organism behavior
|
GO:0051705 |
14 |
0.034
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.033
|
Mouse |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.033
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.033
|
Human |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.033
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.032
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.032
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.032
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.032
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.032
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.031
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.031
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.031
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.031
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.031
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.031
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.031
|
|
|
|
neuron maturation
|
GO:0042551 |
5 |
0.031
|
|
