Homo sapiens

83 known processes

ERCC1

excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

(Aliases: RAD10,COFS4,UV20)

ERCC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide excision repair dna incision GO:0033683 7 0.794
nucleotide excision repair GO:0006289 31 0.413
cellular macromolecule catabolic process GO:0044265 380 0.201
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.190
post embryonic development GO:0009791 2 0.185
cellular response to dna damage stimulus GO:0006974 379 0.176
cellular amino acid metabolic process GO:0006520 116 0.141
regulation of dna metabolic process GO:0051052 153 0.138
dna recombination GO:0006310 77 0.121
nucleoside triphosphate metabolic process GO:0009141 422 0.104
dna repair GO:0006281 198 0.094
regulation of mitotic cell cycle GO:0007346 189 0.094
response to cell cycle checkpoint signaling GO:0072396 4 0.093
purine ribonucleotide catabolic process GO:0009154 404 0.091
double strand break repair via homologous recombination GO:0000724 50 0.088
nucleotide catabolic process GO:0009166 408 0.087
glycosyl compound catabolic process GO:1901658 413 0.085
response to light stimulus GO:0009416 87 0.082
response to biotic stimulus GO:0009607 276 0.077
organophosphate catabolic process GO:0046434 430 0.075
purine nucleotide catabolic process GO:0006195 405 0.075
ribonucleoside triphosphate catabolic process GO:0009203 391 0.071
dna catabolic process GO:0006308 49 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.067
response to oxidative stress GO:0006979 121 0.065
nucleoside phosphate catabolic process GO:1901292 412 0.065
nervous system development GO:0007399 293 0.062
positive regulation of hydrolase activity GO:0051345 331 0.060
mitotic cell cycle GO:0000278 326 0.059
purine containing compound catabolic process GO:0072523 411 0.056
double strand break repair GO:0006302 101 0.051
response to uv GO:0009411 73 0.050
guanosine containing compound metabolic process GO:1901068 244 0.048
negative regulation of chromosome organization GO:2001251 48 0.045
negative regulation of programmed cell death GO:0043069 321 0.045
ribonucleoside triphosphate metabolic process GO:0009199 412 0.043
protein catabolic process GO:0030163 325 0.043
oxidation reduction process GO:0055114 396 0.043
immune response GO:0006955 307 0.042
regulation of telomere maintenance GO:0032204 13 0.042
nucleoside catabolic process GO:0009164 408 0.042
purine ribonucleoside catabolic process GO:0046130 398 0.041
negative regulation of organelle organization GO:0010639 126 0.040
purine ribonucleoside metabolic process GO:0046128 437 0.040
recombinational repair GO:0000725 50 0.039
regulation of purine nucleotide catabolic process GO:0033121 205 0.037
regulation of cellular component biogenesis GO:0044087 281 0.037
cell cycle phase transition GO:0044770 173 0.036
response to oxygen containing compound GO:1901700 369 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
response to dna integrity checkpoint signaling GO:0072402 4 0.034
positive regulation of catabolic process GO:0009896 310 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
dna catabolic process exonucleolytic GO:0000738 17 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.033
epithelium development GO:0060429 227 0.033
negative regulation of homeostatic process GO:0032845 59 0.033
response to abiotic stimulus GO:0009628 336 0.032
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
regulation of cell motility GO:2000145 299 0.032
cellular protein complex assembly GO:0043623 188 0.031
protein oligomerization GO:0051259 173 0.031
amine metabolic process GO:0009308 44 0.031
cytoplasmic transport GO:0016482 379 0.031
negative regulation of apoptotic process GO:0043066 316 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.030
striated muscle contraction GO:0006941 52 0.029
dna double strand break processing GO:0000729 10 0.029
cellular ketone metabolic process GO:0042180 80 0.029
posttranscriptional regulation of gene expression GO:0010608 213 0.028
coenzyme metabolic process GO:0006732 65 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
dna catabolic process endonucleolytic GO:0000737 37 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
apoptotic signaling pathway GO:0097190 268 0.028
regulation of mitotic cell cycle phase transition GO:1901990 118 0.028
cellular macromolecular complex assembly GO:0034622 324 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
single organism cell adhesion GO:0098602 179 0.027
response to dna damage checkpoint signaling GO:0072423 4 0.027
regulation of gtpase activity GO:0043087 180 0.026
regulation of protein catabolic process GO:0042176 155 0.025
gtp catabolic process GO:0006184 237 0.025
microtubule cytoskeleton organization GO:0000226 176 0.025
female gamete generation GO:0007292 2 0.025
regulation of cell cycle GO:0051726 393 0.024
ras protein signal transduction GO:0007265 73 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
mitotic cell cycle phase transition GO:0044772 162 0.024
cellular amine metabolic process GO:0044106 41 0.024
mitotic cell cycle process GO:1903047 286 0.023
rna interference GO:0016246 4 0.023
cell development GO:0048468 328 0.023
cellular modified amino acid metabolic process GO:0006575 64 0.023
regulation of gtp catabolic process GO:0033124 180 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
immune effector process GO:0002252 159 0.022
negative regulation of cellular catabolic process GO:0031330 83 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
negative regulation of catabolic process GO:0009895 104 0.022
actin filament based process GO:0030029 224 0.022
defense response GO:0006952 315 0.021
positive regulation of immune system process GO:0002684 283 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
negative regulation of cell cycle GO:0045786 193 0.021
mitochondrion organization GO:0007005 156 0.021
protein localization to organelle GO:0033365 280 0.020
oogenesis GO:0048477 2 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
epithelial cell differentiation GO:0030855 141 0.020
embryo development GO:0009790 123 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
regulation of homeostatic process GO:0032844 121 0.020
negative regulation of cell cycle process GO:0010948 121 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
regulation of cell cycle process GO:0010564 266 0.019
cellular response to biotic stimulus GO:0071216 71 0.019
intracellular protein transport GO:0006886 270 0.019
regulation of protein processing GO:0070613 150 0.019
response to lipid GO:0033993 206 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
vesicle mediated transport GO:0016192 371 0.019
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
regulation of locomotion GO:0040012 329 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
interspecies interaction between organisms GO:0044419 156 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
system process GO:0003008 349 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
positive regulation of transport GO:0051050 336 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
regulation of transferase activity GO:0051338 355 0.017
protein maturation GO:0051604 233 0.017
gtp metabolic process GO:0046039 239 0.017
mapk cascade GO:0000165 288 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
biological adhesion GO:0022610 331 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
positive regulation of transferase activity GO:0051347 227 0.017
regulation of cell migration GO:0030334 289 0.017
negative regulation of cell cycle phase transition GO:1901988 89 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
sulfur compound metabolic process GO:0006790 101 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of cellular component movement GO:0051270 334 0.016
negative regulation of telomere maintenance GO:0032205 9 0.016
cofactor metabolic process GO:0051186 87 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
response to wounding GO:0009611 168 0.016
cellular response to lipid GO:0071396 127 0.016
cardiac muscle contraction GO:0060048 34 0.016
microtubule based process GO:0007017 210 0.016
regulation of body fluid levels GO:0050878 99 0.016
negative regulation of cell death GO:0060548 345 0.016
neurogenesis GO:0022008 169 0.015
innate immune response GO:0045087 178 0.015
ion transmembrane transport GO:0034220 338 0.015
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.015
response to radiation GO:0009314 151 0.015
single organism reproductive process GO:0044702 98 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of cellular response to stress GO:0080135 244 0.015
dephosphorylation GO:0016311 209 0.014
protein ubiquitination GO:0016567 314 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
regulation of intracellular transport GO:0032386 195 0.014
non recombinational repair GO:0000726 14 0.014
multicellular organismal aging GO:0010259 3 0.014
regulation of protein kinase activity GO:0045859 289 0.014
negative regulation of proteolysis GO:0045861 132 0.014
regulation of cell cycle phase transition GO:1901987 126 0.013
single organism cellular localization GO:1902580 332 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
cellular amide metabolic process GO:0043603 69 0.013
response to external biotic stimulus GO:0043207 261 0.013
glutathione metabolic process GO:0006749 20 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
cellular protein catabolic process GO:0044257 261 0.013
atp metabolic process GO:0046034 176 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
metal ion transport GO:0030001 272 0.013
maintenance of location GO:0051235 112 0.013
protein homooligomerization GO:0051260 100 0.013
hemostasis GO:0007599 76 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
peptide metabolic process GO:0006518 51 0.013
protein targeting GO:0006605 187 0.013
positive regulation of dna metabolic process GO:0051054 73 0.012
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.012
sequestering of calcium ion GO:0051208 17 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
divalent inorganic cation transport GO:0072511 158 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
rho protein signal transduction GO:0007266 26 0.012
negative regulation of protein modification process GO:0031400 200 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
cell activation GO:0001775 213 0.012
positive regulation of protein transport GO:0051222 135 0.012
regulation of meiosis GO:0040020 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
regulation of heart contraction GO:0008016 50 0.012
reproductive process GO:0022414 106 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
regulation of cell growth GO:0001558 135 0.012
negative regulation of protein processing GO:0010955 142 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
neuroblast proliferation GO:0007405 4 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
anatomical structure homeostasis GO:0060249 100 0.011
regulation of immune response GO:0050776 201 0.011
single organism membrane organization GO:0044802 268 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
response to inorganic substance GO:0010035 127 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
response to other organism GO:0051707 261 0.011
adult locomotory behavior GO:0008344 1 0.011
oligodendrocyte differentiation GO:0048709 7 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
determination of adult lifespan GO:0008340 2 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
negative regulation of cellular component organization GO:0051129 235 0.010
taxis GO:0042330 157 0.010
positive regulation of immune response GO:0050778 159 0.010
cell adhesion GO:0007155 325 0.010
translation GO:0006412 132 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
actin cytoskeleton organization GO:0030036 207 0.010
regulation of protein maturation GO:1903317 150 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
negative regulation of protein catabolic process GO:0042177 59 0.010
cell growth GO:0016049 160 0.010
positive regulation of locomotion GO:0040017 186 0.010
transmembrane transport GO:0055085 399 0.010
positive regulation of organelle organization GO:0010638 195 0.010
single organism carbohydrate metabolic process GO:0044723 193 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
positive regulation of cell death GO:0010942 263 0.010
positive regulation of kinase activity GO:0033674 204 0.010

ERCC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
xeroderma pigmentosum DOID:0050427 8 0.577
immune system disease DOID:2914 155 0.301
hematopoietic system disease DOID:74 100 0.301
anemia DOID:2355 55 0.084
bone marrow disease DOID:4961 31 0.074
aplastic anemia DOID:12449 30 0.071
epilepsy syndrome DOID:1826 41 0.040
central nervous system disease DOID:331 186 0.040
brain disease DOID:936 73 0.040
electroclinical syndrome DOID:0050701 32 0.040
neonatal period electroclinical syndrome DOID:0050702 19 0.040
nervous system disease DOID:863 431 0.040
disease of metabolism DOID:0014667 295 0.029
amino acid metabolic disorder DOID:9252 50 0.029
inherited metabolic disorder DOID:655 242 0.029
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
congenital hypoplastic anemia DOID:1342 26 0.013
musculoskeletal system disease DOID:17 223 0.013
connective tissue disease DOID:65 109 0.013
fanconi s anemia DOID:13636 16 0.013
carbohydrate metabolic disorder DOID:2978 55 0.013
idiopathic generalized epilepsy DOID:1827 21 0.011
urinary system disease DOID:18 40 0.010