Homo sapiens

18 known processes

ERO1L

ERO1-like (S. cerevisiae)

(Aliases: ERO1-alpha,ERO1A)

ERO1L biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
4 hydroxyproline metabolic process GO:0019471 5 0.799
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.770
Mouse
protein hydroxylation GO:0018126 9 0.689
alpha amino acid metabolic process GO:1901605 72 0.504
Mouse
cellular amino acid metabolic process GO:0006520 116 0.461
Mouse
protein folding GO:0006457 38 0.421
chaperone mediated protein folding GO:0061077 13 0.337
positive regulation of developmental process GO:0051094 314 0.323
cellular amine metabolic process GO:0044106 41 0.293
regulation of cellular ketone metabolic process GO:0010565 50 0.274
cellular response to topologically incorrect protein GO:0035967 19 0.267
Mouse
endoplasmic reticulum unfolded protein response GO:0030968 16 0.262
Mouse
response to decreased oxygen levels GO:0036293 96 0.243
post embryonic development GO:0009791 2 0.240
oxidation reduction process GO:0055114 396 0.227
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.210
locomotory behavior GO:0007626 1 0.192
intrinsic apoptotic signaling pathway GO:0097193 127 0.169
Mouse
response to endoplasmic reticulum stress GO:0034976 49 0.166
Mouse
peptidyl proline hydroxylation GO:0019511 6 0.151
response to abiotic stimulus GO:0009628 336 0.138
male genitalia development GO:0030539 1 0.115
cardiovascular system development GO:0072358 262 0.107
response to topologically incorrect protein GO:0035966 29 0.106
Mouse
cell chemotaxis GO:0060326 112 0.097
response to hypoxia GO:0001666 96 0.091
regulation of behavior GO:0050795 82 0.090
determination of adult lifespan GO:0008340 2 0.090
response to oxidative stress GO:0006979 121 0.085
cellular ketone metabolic process GO:0042180 80 0.084
growth GO:0040007 202 0.081
apoptotic signaling pathway GO:0097190 268 0.080
Mouse
er nucleus signaling pathway GO:0006984 23 0.075
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.074
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.071
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.070
response to oxygen levels GO:0070482 100 0.068
regulation of chemotaxis GO:0050920 74 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
cellular response to external stimulus GO:0071496 111 0.060
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.059
cellular response to hypoxia GO:0071456 51 0.058
cellular response to oxidative stress GO:0034599 85 0.057
response to oxygen containing compound GO:1901700 369 0.055
cellular modified amino acid metabolic process GO:0006575 64 0.054
Mouse
regulation of cellular response to stress GO:0080135 244 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
cellular response to oxygen levels GO:0071453 55 0.051
protein localization to organelle GO:0033365 280 0.049
monocyte activation GO:0042117 3 0.046
regulation of leukocyte chemotaxis GO:0002688 46 0.046
embryo development GO:0009790 123 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.045
negative regulation of catalytic activity GO:0043086 335 0.045
cellular response to endogenous stimulus GO:0071495 336 0.043
anatomical structure formation involved in morphogenesis GO:0048646 284 0.043
positive regulation of cell proliferation GO:0008284 301 0.041
fatty acid metabolic process GO:0006631 115 0.041
regulation of cell motility GO:2000145 299 0.040
positive regulation of phosphorylation GO:0042327 394 0.040
peptidyl tyrosine modification GO:0018212 170 0.040
heart development GO:0007507 95 0.039
lipid metabolic process GO:0006629 381 0.039
cellular homeostasis GO:0019725 196 0.039
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.039
cellular response to decreased oxygen levels GO:0036294 51 0.039
circulatory system development GO:0072359 262 0.038
axon regeneration GO:0031103 1 0.038
multicellular organismal aging GO:0010259 3 0.038
carbohydrate metabolic process GO:0005975 207 0.037
regulation of protein localization GO:0032880 296 0.037
nucleotide catabolic process GO:0009166 408 0.036
cellular protein complex assembly GO:0043623 188 0.035
positive regulation of transport GO:0051050 336 0.035
cellular response to unfolded protein GO:0034620 16 0.035
Mouse
regulation of cell cycle GO:0051726 393 0.035
response to axon injury GO:0048678 1 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.032
spermatid development GO:0007286 4 0.032
organophosphate catabolic process GO:0046434 430 0.031
chemical homeostasis GO:0048878 306 0.031
Mouse
cell morphogenesis GO:0000902 296 0.031
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
regulation of proteolysis GO:0030162 293 0.031
regulation of growth GO:0040008 165 0.031
system process GO:0003008 349 0.030
regulation of response to oxidative stress GO:1902882 26 0.030
divalent inorganic cation transport GO:0072511 158 0.030
Mouse
regulation of cell adhesion GO:0030155 166 0.030
amine metabolic process GO:0009308 44 0.030
regulation of cell migration GO:0030334 289 0.029
positive regulation of protein secretion GO:0050714 60 0.029
negative regulation of hydrolase activity GO:0051346 182 0.029
actin filament based process GO:0030029 224 0.028
negative regulation of cell cycle GO:0045786 193 0.028
cellular lipid metabolic process GO:0044255 303 0.027
peptidyl tyrosine phosphorylation GO:0018108 170 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
regulation of response to external stimulus GO:0032101 222 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
head development GO:0060322 108 0.026
positive regulation of cell death GO:0010942 263 0.026
actin filament organization GO:0007015 128 0.026
epithelium development GO:0060429 227 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
regulation of cellular response to oxidative stress GO:1900407 26 0.025
vasculature development GO:0001944 181 0.025
defense response GO:0006952 315 0.024
response to lithium ion GO:0010226 2 0.024
positive regulation of protein transport GO:0051222 135 0.024
sulfur compound biosynthetic process GO:0044272 38 0.024
cellular component morphogenesis GO:0032989 314 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
cellular carbohydrate metabolic process GO:0044262 84 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
cellular response to lithium ion GO:0071285 2 0.024
regulation of axon guidance GO:1902667 3 0.024
positive regulation of secretion GO:0051047 116 0.024
peptidyl proline modification GO:0018208 15 0.023
chemotaxis GO:0006935 157 0.023
carboxylic acid biosynthetic process GO:0046394 97 0.023
regulation of cell growth GO:0001558 135 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
cytoplasmic transport GO:0016482 379 0.023
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.022
secretion by cell GO:0032940 226 0.022
response to extracellular stimulus GO:0009991 85 0.022
single organism reproductive process GO:0044702 98 0.022
single organism cell adhesion GO:0098602 179 0.022
purine containing compound catabolic process GO:0072523 411 0.021
positive regulation of keratinocyte migration GO:0051549 4 0.021
regulation of homeostatic process GO:0032844 121 0.021
Mouse
cation transmembrane transport GO:0098655 238 0.021
developmental process involved in reproduction GO:0003006 66 0.021
camp metabolic process GO:0046058 61 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 4 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
muscle structure development GO:0061061 98 0.021
post embryonic organ development GO:0048569 1 0.021
positive regulation of cell motility GO:2000147 177 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
behavior GO:0007610 112 0.020
organic acid biosynthetic process GO:0016053 97 0.020
positive regulation of secretion by cell GO:1903532 108 0.020
response to inorganic substance GO:0010035 127 0.020
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
response to biotic stimulus GO:0009607 276 0.020
cell projection organization GO:0030030 252 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
response to activity GO:0014823 0 0.019
protein stabilization GO:0050821 64 0.019
embryonic placenta development GO:0001892 1 0.019
regulation of protein secretion GO:0050708 86 0.019
regulation of cysteine type endopeptidase activity GO:2000116 127 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.018
central nervous system development GO:0007417 123 0.018
mitotic cell cycle GO:0000278 326 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
gtp metabolic process GO:0046039 239 0.018
muscle cell cellular homeostasis GO:0046716 3 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
regulation of multicellular organism growth GO:0040014 8 0.018
sex differentiation GO:0007548 45 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
hindbrain development GO:0030902 3 0.018
regulation of meiotic cell cycle GO:0051445 4 0.017
positive regulation of growth GO:0045927 58 0.017
rhythmic behavior GO:0007622 2 0.017
reproduction GO:0000003 63 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
regulation of kinase activity GO:0043549 314 0.017
cerebral cortex radially oriented cell migration GO:0021799 1 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
regulation of keratinocyte migration GO:0051547 4 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
visual behavior GO:0007632 2 0.017
spermatid differentiation GO:0048515 4 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
nuclear transport GO:0051169 179 0.017
nervous system development GO:0007399 293 0.017
reproductive process GO:0022414 106 0.017
positive regulation of chemotaxis GO:0050921 57 0.016
regulation of oxidative stress induced cell death GO:1903201 24 0.016
cellular response to organonitrogen compound GO:0071417 124 0.016
calcium ion transport GO:0006816 147 0.016
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.016
microtubule based process GO:0007017 210 0.016
endocytosis GO:0006897 159 0.016
response to radiation GO:0009314 151 0.016
tissue morphogenesis GO:0048729 96 0.016
myosin filament organization GO:0031033 2 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
positive regulation of embryonic development GO:0040019 6 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
regulation of cell cycle process GO:0010564 266 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
organ morphogenesis GO:0009887 147 0.016
regulation of protein catabolic process GO:0042176 155 0.016
single organism cellular localization GO:1902580 332 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
g protein coupled receptor signaling pathway GO:0007186 207 0.016
regulation of lipid biosynthetic process GO:0046890 47 0.016
response to cytokine GO:0034097 232 0.016
positive regulation of developmental growth GO:0048639 16 0.016
positive regulation of protein catabolic process GO:0045732 75 0.016
secretion GO:0046903 254 0.016
regulation of transferase activity GO:0051338 355 0.016
primary neural tube formation GO:0014020 3 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
regulation of cellular component movement GO:0051270 334 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.015
glycolytic process GO:0006096 17 0.015
somatic muscle development GO:0007525 1 0.015
myoblast fusion GO:0007520 1 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
actin cytoskeleton organization GO:0030036 207 0.015
negative regulation of protein processing GO:0010955 142 0.015
neuroblast proliferation GO:0007405 4 0.015
brain development GO:0007420 97 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.015
sensory perception of smell GO:0007608 2 0.015
membrane protein proteolysis GO:0033619 38 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
peptidyl lysine modification GO:0018205 144 0.015
single organism membrane organization GO:0044802 268 0.015
circadian behavior GO:0048512 2 0.015
response to hormone GO:0009725 175 0.015
chromatin modification GO:0016568 298 0.015
negative regulation of cell death GO:0060548 345 0.015
negative regulation of proteolysis GO:0045861 132 0.015
response to ionizing radiation GO:0010212 65 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
regulation of carbohydrate metabolic process GO:0006109 54 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
regulation of t cell chemotaxis GO:0010819 7 0.015
response to organonitrogen compound GO:0010243 156 0.014
anatomical structure homeostasis GO:0060249 100 0.014
translation GO:0006412 132 0.014
protein oligomerization GO:0051259 173 0.014
response to growth factor GO:0070848 205 0.014
neuron differentiation GO:0030182 138 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
regulation of secretion by cell GO:1903530 177 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
positive regulation of transferase activity GO:0051347 227 0.014
regeneration GO:0031099 4 0.014
cellular response to toxic substance GO:0097237 4 0.014
epithelial cell differentiation GO:0030855 141 0.014
neuron projection development GO:0031175 106 0.014
neuron projection regeneration GO:0031102 1 0.014
regulation of cell development GO:0060284 161 0.014
blood vessel development GO:0001568 172 0.014
regulation of endopeptidase activity GO:0052548 170 0.013
regulation of protein maturation GO:1903317 150 0.013
regulation of locomotion GO:0040012 329 0.013
cellular protein catabolic process GO:0044257 261 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
regulation of secretion GO:0051046 194 0.013
cell junction assembly GO:0034329 67 0.013
regulation of glucose metabolic process GO:0010906 28 0.013
oocyte differentiation GO:0009994 2 0.013
receptor transactivation GO:0035624 4 0.013
heart morphogenesis GO:0003007 48 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
ectodermal placode development GO:0071696 1 0.013
response to starvation GO:0042594 59 0.013
regulation of protein transport GO:0051223 213 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
mapk cascade GO:0000165 288 0.013
carbohydrate catabolic process GO:0016052 36 0.013
reproductive system development GO:0061458 56 0.013
oogenesis GO:0048477 2 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
negative regulation of growth GO:0045926 97 0.013
oocyte development GO:0048599 1 0.013
small molecule biosynthetic process GO:0044283 157 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
pyruvate metabolic process GO:0006090 26 0.013
cellular ion homeostasis GO:0006873 168 0.013
Mouse
peripheral nervous system development GO:0007422 2 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
regulation of protein kinase activity GO:0045859 289 0.012
protein export from nucleus GO:0006611 29 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
cell cycle phase transition GO:0044770 173 0.012
generation of neurons GO:0048699 152 0.012
regulation of developmental growth GO:0048638 30 0.012
regulation of protein processing GO:0070613 150 0.012
positive regulation of catabolic process GO:0009896 310 0.012
adult locomotory behavior GO:0008344 1 0.012
cell growth GO:0016049 160 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
blood vessel morphogenesis GO:0048514 162 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
cation transport GO:0006812 331 0.012
Mouse
neuromuscular junction development GO:0007528 3 0.012
positive regulation of hormone biosynthetic process GO:0046886 4 0.012
protein maturation GO:0051604 233 0.012
Mouse
coenzyme metabolic process GO:0006732 65 0.012
cardiac muscle tissue development GO:0048738 39 0.012
regulation of lymphocyte chemotaxis GO:1901623 12 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
anion transport GO:0006820 161 0.011
regulation of leukocyte migration GO:0002685 63 0.011
single organism behavior GO:0044708 28 0.011
cell death in response to oxidative stress GO:0036473 29 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
membrane organization GO:0061024 292 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
regulation of intracellular transport GO:0032386 195 0.011
limbic system development GO:0021761 3 0.011
somitogenesis GO:0001756 2 0.011
reproductive structure development GO:0048608 55 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
lipid biosynthetic process GO:0008610 177 0.011
memory GO:0007613 3 0.011
leukocyte chemotaxis GO:0030595 76 0.011
protein homooligomerization GO:0051260 100 0.011
small molecule catabolic process GO:0044282 92 0.011
synaptic vesicle endocytosis GO:0048488 2 0.011
negative regulation of catabolic process GO:0009895 104 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
muscle cell differentiation GO:0042692 63 0.011
transmembrane transport GO:0055085 399 0.011
female gamete generation GO:0007292 2 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
organelle assembly GO:0070925 176 0.011
response to wounding GO:0009611 168 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.011
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
developmental growth GO:0048589 48 0.011
nucleoside catabolic process GO:0009164 408 0.011
sleep GO:0030431 2 0.011
response to nitric oxide GO:0071731 4 0.011
positive regulation of cell migration GO:0030335 172 0.011
regulation of multi organism process GO:0043900 157 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
endomembrane system organization GO:0010256 196 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
response to external biotic stimulus GO:0043207 261 0.011
sulfur compound metabolic process GO:0006790 101 0.011
cell development GO:0048468 328 0.010
response to tumor necrosis factor GO:0034612 76 0.010
response to fungus GO:0009620 4 0.010
ion homeostasis GO:0050801 230 0.010
Mouse
aging GO:0007568 66 0.010
negative regulation of protein maturation GO:1903318 142 0.010
protein catabolic process GO:0030163 325 0.010
regulation of dna metabolic process GO:0051052 153 0.010
maintenance of location GO:0051235 112 0.010
Mouse
ventricular septum morphogenesis GO:0060412 3 0.010
peptidyl serine modification GO:0018209 106 0.010
peptidyl serine phosphorylation GO:0018105 101 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
positive regulation of cell cycle GO:0045787 140 0.010
regulation of binding GO:0051098 111 0.010
male sex differentiation GO:0046661 25 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
cell aging GO:0007569 52 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.010
epithelium migration GO:0090132 119 0.010
protein acetylation GO:0006473 116 0.010

ERO1L disease predictions

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 88 0.075
musculoskeletal system disease DOID:17 223 0.075
connective tissue disease DOID:65 109 0.075
osteochondrodysplasia DOID:2256 35 0.065
osteogenesis imperfecta DOID:12347 13 0.065
bone development disease DOID:0080006 55 0.065
cancer DOID:162 167 0.039
disease of cellular proliferation DOID:14566 174 0.039
organ system cancer DOID:0050686 164 0.039
disease of metabolism DOID:0014667 295 0.038
retinal disease DOID:5679 118 0.021
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
nervous system disease DOID:863 431 0.021
eye disease DOID:5614 149 0.021
central nervous system disease DOID:331 186 0.018
disease of mental health DOID:150 70 0.013
inherited metabolic disorder DOID:655 242 0.012
carbohydrate metabolic disorder DOID:2978 55 0.011
neurodegenerative disease DOID:1289 102 0.011
glycogen storage disease DOID:2747 10 0.011
glycogen metabolism disorder DOID:0050728 10 0.011