Homo sapiens

149 known processes

ESR1

estrogen receptor 1

(Aliases: NR3A1,ESR,Era,ESRA,DKFZp686N23123,ER)

ESR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 1.000
Human
intracellular receptor signaling pathway GO:0030522 104 1.000
intracellular estrogen receptor signaling pathway GO:0030520 23 1.000
regulation of cellular ketone metabolic process GO:0010565 50 1.000
epithelial cell differentiation GO:0030855 141 1.000
Mouse Rat
cellular response to endogenous stimulus GO:0071495 336 1.000
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 1.000
cell development GO:0048468 328 1.000
Mouse Rat
tube morphogenesis GO:0035239 95 1.000
Mouse
response to hormone GO:0009725 175 1.000
epithelium development GO:0060429 227 1.000
Mouse Rat
negative regulation of cell death GO:0060548 345 1.000
Rat
tissue morphogenesis GO:0048729 96 1.000
Mouse
chromatin organization GO:0006325 351 1.000
response to genistein GO:0033595 1 1.000
chromatin modification GO:0016568 298 1.000
cellular response to nitrogen compound GO:1901699 144 1.000
positive regulation of cell proliferation GO:0008284 301 1.000
Mouse
response to estrogen GO:0043627 47 1.000
heart development GO:0007507 95 1.000
response to steroid hormone GO:0048545 80 1.000
hormone mediated signaling pathway GO:0009755 22 1.000
intracellular steroid hormone receptor signaling pathway GO:0030518 61 1.000
covalent chromatin modification GO:0016569 254 1.000
response to estradiol GO:0032355 23 1.000
digestive system development GO:0055123 75 1.000
cellular amino acid metabolic process GO:0006520 116 1.000
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 1.000
chordate embryonic development GO:0043009 34 1.000
organ morphogenesis GO:0009887 147 1.000
Mouse
negative regulation of programmed cell death GO:0043069 321 1.000
nervous system development GO:0007399 293 1.000
response to oxygen containing compound GO:1901700 369 1.000
carbohydrate metabolic process GO:0005975 207 1.000
Fly
male sex differentiation GO:0046661 25 1.000
Mouse Rat
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 1.000
response to organic cyclic compound GO:0014070 204 1.000
cellular ketone metabolic process GO:0042180 80 0.999
tube development GO:0035295 125 0.999
Mouse
muscle cell proliferation GO:0033002 35 0.999
Rat
cellular response to oxygen containing compound GO:1901701 276 0.999
Rat
regeneration GO:0031099 4 0.999
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.999
Rat
positive regulation of phosphorylation GO:0042327 394 0.999
Rat
protein targeting to nucleus GO:0044744 104 0.999
gland development GO:0048732 48 0.999
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.999
negative regulation of cell proliferation GO:0008285 228 0.999
Rat
response to organonitrogen compound GO:0010243 156 0.999
response to lipid GO:0033993 206 0.998
enzyme linked receptor protein signaling pathway GO:0007167 303 0.998
Rat
defense response GO:0006952 315 0.998
behavior GO:0007610 112 0.998
myeloid cell differentiation GO:0030099 117 0.998
response to nitrogen compound GO:1901698 184 0.998
muscle structure development GO:0061061 98 0.997
positive regulation of programmed cell death GO:0043068 249 0.997
regulation of epithelial cell proliferation GO:0050678 113 0.997
response to abiotic stimulus GO:0009628 336 0.997
regulation of myeloid cell differentiation GO:0045637 81 0.997
regulation of carbohydrate metabolic process GO:0006109 54 0.997
heart morphogenesis GO:0003007 48 0.997
positive regulation of developmental process GO:0051094 314 0.997
response to lipopolysaccharide GO:0032496 70 0.996
negative regulation of epithelial cell proliferation GO:0050680 48 0.996
positive regulation of glucocorticoid receptor signaling pathway GO:2000324 1 0.996
chemical homeostasis GO:0048878 306 0.996
Rat
neuron apoptotic process GO:0051402 39 0.996
Rat
regulation of neuron apoptotic process GO:0043523 35 0.996
Rat
steroid hormone mediated signaling pathway GO:0043401 12 0.995
negative regulation of apoptotic process GO:0043066 316 0.995
regulation of intracellular protein transport GO:0033157 123 0.994
response to peptide GO:1901652 65 0.994
regulation of cell development GO:0060284 161 0.994
regulation of cell cycle GO:0051726 393 0.994
response to molecule of bacterial origin GO:0002237 82 0.994
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.994
central nervous system development GO:0007417 123 0.993
hindbrain development GO:0030902 3 0.993
intrinsic apoptotic signaling pathway GO:0097193 127 0.993
epithelial cell development GO:0002064 34 0.993
Mouse Rat
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.992
regulation of cell migration GO:0030334 289 0.992
response to alcohol GO:0097305 64 0.992
actin filament based process GO:0030029 224 0.992
response to bacterium GO:0009617 144 0.991
positive regulation of apoptotic process GO:0043065 246 0.991
embryonic morphogenesis GO:0048598 85 0.991
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.990
regulation of smooth muscle cell proliferation GO:0048660 28 0.990
Rat
cardiac muscle tissue development GO:0048738 39 0.990
regulation of cell differentiation GO:0045595 393 0.990
cellular component morphogenesis GO:0032989 314 0.989
mammary gland development GO:0030879 17 0.989
Mouse
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.989
cardiovascular system development GO:0072358 262 0.988
reproductive process GO:0022414 106 0.988
Mouse Rat
positive regulation of immune system process GO:0002684 283 0.988
nucleocytoplasmic transport GO:0006913 176 0.985
single organism carbohydrate metabolic process GO:0044723 193 0.985
oogenesis GO:0048477 2 0.985
hormone metabolic process GO:0042445 61 0.984
Mouse
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.984
Rat
response to drug GO:0042493 81 0.984
response to ketone GO:1901654 19 0.984
muscle tissue development GO:0060537 62 0.983
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.983
neuron death GO:0070997 65 0.983
Rat
protein import GO:0017038 130 0.982
post embryonic development GO:0009791 2 0.982
amine metabolic process GO:0009308 44 0.982
mapk cascade GO:0000165 288 0.981
Rat
protein targeting GO:0006605 187 0.981
positive regulation of protein transport GO:0051222 135 0.981
positive regulation of oxidoreductase activity GO:0051353 26 0.980
development of primary male sexual characteristics GO:0046546 23 0.979
Mouse Rat
negative regulation of cellular amine metabolic process GO:0033239 3 0.979
circulatory system development GO:0072359 262 0.979
regulation of cellular amine metabolic process GO:0033238 11 0.978
cerebellum development GO:0021549 2 0.977
muscle organ development GO:0007517 56 0.977
small gtpase mediated signal transduction GO:0007264 78 0.976
cellular response to peptide GO:1901653 59 0.975
hexose metabolic process GO:0019318 55 0.974
monosaccharide metabolic process GO:0005996 74 0.973
epithelial cell proliferation GO:0050673 128 0.973
Mouse Rat
cellular response to lipid GO:0071396 127 0.972
regulation of mapk cascade GO:0043408 262 0.972
Rat
single organism cellular localization GO:1902580 332 0.970
positive regulation of intracellular protein transport GO:0090316 76 0.970
protein localization to nucleus GO:0034504 136 0.969
limbic system development GO:0021761 3 0.968
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.968
neurogenesis GO:0022008 169 0.968
reactive oxygen species biosynthetic process GO:1903409 4 0.967
regulation of erk1 and erk2 cascade GO:0070372 99 0.966
Rat
striated muscle tissue development GO:0014706 59 0.966
gene silencing GO:0016458 49 0.965
i kappab kinase nf kappab signaling GO:0007249 166 0.964
regulation of locomotion GO:0040012 329 0.964
morphogenesis of an epithelium GO:0002009 60 0.964
Mouse
positive regulation of mapk cascade GO:0043410 190 0.964
Rat
metencephalon development GO:0022037 2 0.963
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 5 0.962
single organism nuclear import GO:1902593 104 0.962
bmp signaling pathway involved in heart development GO:0061312 3 0.961
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.958
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.958
positive regulation of defense response GO:0031349 87 0.958
response to peptide hormone GO:0043434 61 0.958
regulation of cell motility GO:2000145 299 0.957
developmental growth GO:0048589 48 0.956
Mouse
epithelial tube morphogenesis GO:0060562 38 0.956
Mouse
carbon catabolite activation of transcription GO:0045991 3 0.956
regulation of cytokine production GO:0001817 232 0.956
methylation dependent chromatin silencing GO:0006346 3 0.955
regulation of neuron death GO:1901214 56 0.954
Rat
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.954
histone modification GO:0016570 251 0.952
cellular response to hormone stimulus GO:0032870 125 0.951
negative regulation of cell differentiation GO:0045596 171 0.951
leukocyte differentiation GO:0002521 98 0.949
female gamete generation GO:0007292 2 0.949
positive regulation of cell death GO:0010942 263 0.945
negative regulation of phosphorus metabolic process GO:0010563 267 0.945
cellular carbohydrate metabolic process GO:0044262 84 0.945
response to extracellular stimulus GO:0009991 85 0.945
brain development GO:0007420 97 0.945
negative regulation of intracellular signal transduction GO:1902532 183 0.943
regulation of striated muscle tissue development GO:0016202 26 0.942
regulation of immune response GO:0050776 201 0.942
regulation of intracellular transport GO:0032386 195 0.941
regulation of cellular component movement GO:0051270 334 0.940
regulation of establishment of protein localization GO:0070201 242 0.940
posttranscriptional regulation of gene expression GO:0010608 213 0.940
actin cytoskeleton organization GO:0030036 207 0.940
single organism reproductive process GO:0044702 98 0.939
Mouse Rat
signal transduction by phosphorylation GO:0023014 297 0.939
Rat
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.938
apoptotic signaling pathway GO:0097190 268 0.937
morphogenesis of embryonic epithelium GO:0016331 4 0.935
canonical wnt signaling pathway GO:0060070 116 0.935
regulation of cellular amino acid metabolic process GO:0006521 6 0.934
gland morphogenesis GO:0022612 8 0.933
Mouse
neural tube formation GO:0001841 3 0.932
nuclear transport GO:0051169 179 0.931
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.928
immune system development GO:0002520 195 0.926
regulation of leukocyte differentiation GO:1902105 61 0.926
cellular amine metabolic process GO:0044106 41 0.924
positive regulation of cell motility GO:2000147 177 0.923
hematopoietic or lymphoid organ development GO:0048534 186 0.922
regulation of protein localization to nucleus GO:1900180 85 0.922
regulation of muscle tissue development GO:1901861 26 0.922
positive regulation of cytoplasmic transport GO:1903651 82 0.921
cellular response to peptide hormone stimulus GO:0071375 56 0.920
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.920
intracellular bile acid receptor signaling pathway GO:0038185 1 0.918
regulation of oxidoreductase activity GO:0051341 43 0.917
cellular response to nutrient GO:0031670 12 0.917
regulation of defense response GO:0031347 154 0.916
growth GO:0040007 202 0.916
Mouse
response to insulin GO:0032868 45 0.915
regulation of protein import into nucleus GO:0042306 78 0.915
multicellular organismal reproductive process GO:0048609 40 0.914
Mouse Rat
cell type specific apoptotic process GO:0097285 125 0.913
Rat
maternal process involved in female pregnancy GO:0060135 5 0.909
Mouse Rat
embryonic organ development GO:0048568 36 0.908
positive regulation of immune response GO:0050778 159 0.907
glucose metabolic process GO:0006006 45 0.905
determination of adult lifespan GO:0008340 2 0.904
digestive tract development GO:0048565 75 0.904
embryonic placenta development GO:0001892 1 0.902
cellular response to steroid hormone stimulus GO:0071383 37 0.899
response to alkaloid GO:0043279 20 0.895
digestive tract morphogenesis GO:0048546 56 0.895
eye development GO:0001654 42 0.894
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.894
response to acid chemical GO:0001101 66 0.893
protein oligomerization GO:0051259 173 0.892
peptidyl tyrosine phosphorylation GO:0018108 170 0.892
response to biotic stimulus GO:0009607 276 0.887
regulation of kinase activity GO:0043549 314 0.883
chromatin remodeling GO:0006338 55 0.882
histone h4 acetylation GO:0043967 47 0.882
reactive nitrogen species metabolic process GO:2001057 3 0.880
regulation of epidermal cell differentiation GO:0045604 15 0.876
regulation of protein kinase activity GO:0045859 289 0.875
reproductive structure development GO:0048608 55 0.873
Mouse Rat
cell cell signaling GO:0007267 155 0.873
regulation of muscle organ development GO:0048634 27 0.868
cellular response to organonitrogen compound GO:0071417 124 0.868
neuron differentiation GO:0030182 138 0.864
nuclear import GO:0051170 106 0.863
actin filament organization GO:0007015 128 0.855
histone acetylation GO:0016573 93 0.850
embryo development ending in birth or egg hatching GO:0009792 34 0.848
embryonic hemopoiesis GO:0035162 4 0.848
regulation of carbohydrate biosynthetic process GO:0043255 27 0.845
establishment of protein localization to organelle GO:0072594 172 0.843
rhythmic process GO:0048511 31 0.837
Mouse
developmental growth involved in morphogenesis GO:0060560 23 0.836
Mouse
mitotic cell cycle GO:0000278 326 0.836
retinoic acid receptor signaling pathway GO:0048384 13 0.834
immune response GO:0006955 307 0.834
peptidyl tyrosine modification GO:0018212 170 0.832
ameboidal type cell migration GO:0001667 135 0.829
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.829
response to wounding GO:0009611 168 0.828
metal ion homeostasis GO:0055065 169 0.828
Rat
anatomical structure formation involved in morphogenesis GO:0048646 284 0.824
embryo development GO:0009790 123 0.824
urogenital system development GO:0001655 65 0.821
Mouse
head development GO:0060322 108 0.815
regulation of methylation dependent chromatin silencing GO:0090308 3 0.809
hemopoiesis GO:0030097 180 0.806
cell morphogenesis GO:0000902 296 0.806
negative regulation of developmental process GO:0051093 247 0.801
regulation of growth GO:0040008 165 0.798
response to ethanol GO:0045471 11 0.798
response to nutrient levels GO:0031667 81 0.794
regulation of ossification GO:0030278 58 0.792
positive regulation of protein import into nucleus GO:0042307 46 0.791
regulation of lipid metabolic process GO:0019216 96 0.791
Rat
reactive oxygen species metabolic process GO:0072593 75 0.782
negative regulation of neuron apoptotic process GO:0043524 23 0.782
response to ionizing radiation GO:0010212 65 0.778
ras protein signal transduction GO:0007265 73 0.777
peptidyl lysine acetylation GO:0018394 101 0.775
regulation of nucleocytoplasmic transport GO:0046822 98 0.773
cellular response to dna damage stimulus GO:0006974 379 0.773
negative regulation of phosphorylation GO:0042326 174 0.770
positive regulation of transcription by galactose GO:0000411 1 0.769
regulation of behavior GO:0050795 82 0.766
female gonad development GO:0008585 10 0.761
Mouse
peptidyl lysine modification GO:0018205 144 0.755
positive regulation of cytokine production GO:0001819 167 0.752
cytoplasmic transport GO:0016482 379 0.749
response to transforming growth factor beta GO:0071559 94 0.749
positive regulation of intracellular transport GO:0032388 104 0.748
cellular response to organic cyclic compound GO:0071407 127 0.747
prostate gland development GO:0030850 3 0.747
Mouse
response to cytokine GO:0034097 232 0.746
cardiac chamber development GO:0003205 30 0.741
activation of immune response GO:0002253 114 0.738
regulation of gene expression epigenetic GO:0040029 73 0.738
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.736
tissue regeneration GO:0042246 3 0.731
bmp signaling pathway GO:0030509 49 0.730
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.730
regulation of cell growth GO:0001558 135 0.728
regulation of feeding behavior GO:0060259 3 0.728
gastrulation GO:0007369 51 0.723
positive regulation of cell migration GO:0030335 172 0.716
regulation of nitric oxide synthase activity GO:0050999 11 0.714
maintenance of location GO:0051235 112 0.714
cell growth GO:0016049 160 0.713
response to inorganic substance GO:0010035 127 0.711
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.710
modification of morphology or physiology of other organism GO:0035821 43 0.709
positive regulation of cell development GO:0010720 92 0.709
skeletal system development GO:0001501 79 0.704
Rat
regulation of glucose metabolic process GO:0010906 28 0.704
protein ubiquitination GO:0016567 314 0.703
embryonic epithelial tube formation GO:0001838 4 0.697
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.695
positive regulation of cellular amine metabolic process GO:0033240 7 0.687
response to hydroxyisoflavone GO:0033594 1 0.683
regulation of protein targeting GO:1903533 91 0.681
regulation of reactive oxygen species metabolic process GO:2000377 41 0.670
response to nutrient GO:0007584 20 0.651
system process GO:0003008 349 0.649
regulation of transferase activity GO:0051338 355 0.649
erk1 and erk2 cascade GO:0070371 104 0.647
Rat
oxidation reduction process GO:0055114 396 0.646
negative regulation of multicellular organismal process GO:0051241 317 0.645
positive regulation of proteolysis GO:0045862 142 0.643
regulation of muscle system process GO:0090257 53 0.641
cellular response to nutrient levels GO:0031669 69 0.633
internal peptidyl lysine acetylation GO:0018393 97 0.631
lipid localization GO:0010876 106 0.631
positive regulation of protein localization to nucleus GO:1900182 48 0.630
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.630
regulation of protein transport GO:0051223 213 0.628
carbohydrate biosynthetic process GO:0016051 42 0.628
positive regulation of innate immune response GO:0045089 79 0.624
wound healing GO:0042060 115 0.621
dna templated transcription initiation GO:0006352 35 0.615
negative regulation of phosphate metabolic process GO:0045936 267 0.615
cellular macromolecular complex assembly GO:0034622 324 0.608
lipid biosynthetic process GO:0008610 177 0.608
fatty acid metabolic process GO:0006631 115 0.607
forebrain development GO:0030900 26 0.606
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.605
cognition GO:0050890 43 0.605
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.604
response to cocaine GO:0042220 1 0.604
regulation of innate immune response GO:0045088 97 0.590
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.589
regulation of actin cytoskeleton organization GO:0032956 116 0.583
response to toxic substance GO:0009636 37 0.582
morphogenesis of a branching structure GO:0001763 21 0.582
Mouse
cardiocyte differentiation GO:0035051 23 0.579
negative regulation of myeloid cell differentiation GO:0045638 42 0.578
skeletal muscle tissue development GO:0007519 24 0.578
regulation of oocyte development GO:0060281 1 0.576
regulation of glucocorticoid receptor signaling pathway GO:2000322 2 0.574
ovulation cycle GO:0042698 9 0.574
Mouse
viral life cycle GO:0019058 132 0.565
telencephalon development GO:0021537 17 0.561
response to oxidative stress GO:0006979 121 0.557
jak stat cascade GO:0007259 46 0.554
steroid biosynthetic process GO:0006694 46 0.553
memory GO:0007613 3 0.552
response to activity GO:0014823 0 0.552
internal protein amino acid acetylation GO:0006475 101 0.548
negative regulation of cholesterol storage GO:0010887 4 0.547
generation of neurons GO:0048699 152 0.541
regulation of keratinocyte differentiation GO:0045616 11 0.539
response to xenobiotic stimulus GO:0009410 30 0.538
Zebrafish
response to glucocorticoid GO:0051384 13 0.533
cell morphogenesis involved in differentiation GO:0000904 144 0.533
negative regulation of protein phosphorylation GO:0001933 140 0.533
regulation of transcription involved in cell fate commitment GO:0060850 6 0.528
response to external biotic stimulus GO:0043207 261 0.528
muscle organ morphogenesis GO:0048644 19 0.525
neuron development GO:0048666 113 0.521
regulation of proteolysis GO:0030162 293 0.517
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.517
multicellular organismal homeostasis GO:0048871 67 0.512
cellular response to oxidative stress GO:0034599 85 0.508
positive regulation of peptidase activity GO:0010952 88 0.504
cellular response to insulin stimulus GO:0032869 41 0.496
negative regulation of protein metabolic process GO:0051248 391 0.493
chromatin silencing GO:0006342 12 0.486
regulation of multi organism process GO:0043900 157 0.485
response to hydrogen peroxide GO:0042542 40 0.478
positive regulation of locomotion GO:0040017 186 0.477
cellular lipid metabolic process GO:0044255 303 0.476
Rat
response to corticosteroid GO:0031960 15 0.475
regulation of wnt signaling pathway GO:0030111 123 0.474
purine nucleotide catabolic process GO:0006195 405 0.471
regulation of epidermis development GO:0045682 19 0.468
positive regulation of ras gtpase activity GO:0032320 117 0.467
response to reactive oxygen species GO:0000302 61 0.467
regulation of cholesterol storage GO:0010885 8 0.457
protein acylation GO:0043543 138 0.456
hormone biosynthetic process GO:0042446 22 0.456
histone methylation GO:0016571 60 0.454
myeloid leukocyte differentiation GO:0002573 60 0.449
androgen receptor signaling pathway GO:0030521 34 0.447
wnt signaling pathway GO:0016055 156 0.447
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.446
macromolecule methylation GO:0043414 97 0.443
modification by host of symbiont morphology or physiology GO:0051851 26 0.442
cellular macromolecule catabolic process GO:0044265 380 0.441
purine ribonucleoside metabolic process GO:0046128 437 0.436
glucose homeostasis GO:0042593 31 0.433
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.432
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.431
corticosteroid receptor signaling pathway GO:0031958 5 0.430
protein autophosphorylation GO:0046777 123 0.429
posttranscriptional gene silencing GO:0016441 25 0.428
receptor mediated endocytosis GO:0006898 84 0.426
fear response GO:0042596 0 0.422
regulation of receptor biosynthetic process GO:0010869 15 0.422
positive regulation of cell differentiation GO:0045597 211 0.422
outflow tract septum morphogenesis GO:0003148 4 0.422
blood circulation GO:0008015 113 0.420
nitric oxide metabolic process GO:0046209 22 0.419
regulation of monooxygenase activity GO:0032768 22 0.418
atp dependent chromatin remodeling GO:0043044 25 0.416
prostate gland morphogenesis GO:0060512 1 0.415
Mouse
negative regulation of neuron death GO:1901215 32 0.407
Rat
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.406
regulation of protein localization GO:0032880 296 0.403
regulation of canonical wnt signaling pathway GO:0060828 88 0.403
reproductive system development GO:0061458 56 0.402
Mouse Rat
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.392
glycosyl compound catabolic process GO:1901658 413 0.390
regulation of response to external stimulus GO:0032101 222 0.381
carbon catabolite regulation of transcription GO:0045990 5 0.377
cellular response to acid chemical GO:0071229 44 0.377
neural tube development GO:0021915 9 0.377
regulation of protein binding GO:0043393 66 0.374
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.373
mammary gland epithelium development GO:0061180 10 0.372
Mouse
negative regulation of binding GO:0051100 57 0.367
regulation of cell adhesion GO:0030155 166 0.366
positive regulation of transport GO:0051050 336 0.358
posttranscriptional gene silencing by rna GO:0035194 25 0.358
regulation of transcription by galactose GO:0000409 1 0.357
stem cell differentiation GO:0048863 93 0.356
lymphocyte differentiation GO:0030098 35 0.355
positive regulation of leukocyte activation GO:0002696 80 0.352
muscle cell differentiation GO:0042692 63 0.351
cell junction organization GO:0034330 79 0.350
negative regulation of protein binding GO:0032091 35 0.350
signal transduction by p53 class mediator GO:0072331 72 0.349
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter GO:0035947 1 0.345
cardiac chamber morphogenesis GO:0003206 26 0.344
male gonad development GO:0008584 23 0.342
Mouse Rat
regulation of immune effector process GO:0002697 91 0.341
endocytosis GO:0006897 159 0.339
regulation of retinoic acid receptor signaling pathway GO:0048385 9 0.338
tissue homeostasis GO:0001894 63 0.336
cellular response to external stimulus GO:0071496 111 0.334
cardiac ventricle morphogenesis GO:0003208 20 0.324
gonad development GO:0008406 34 0.324
Mouse Rat
in utero embryonic development GO:0001701 8 0.323
receptor biosynthetic process GO:0032800 18 0.322
response to hypoxia GO:0001666 96 0.320
epidermal cell differentiation GO:0009913 45 0.316
single organism behavior GO:0044708 28 0.310
multicellular organism reproduction GO:0032504 42 0.310
Mouse Rat
negative regulation of immune system process GO:0002683 136 0.310
developmental process involved in reproduction GO:0003006 66 0.309
Mouse Rat
regulation of cysteine type endopeptidase activity GO:2000116 127 0.309
protein deacylation GO:0035601 39 0.306
regulation of cytoplasmic transport GO:1903649 149 0.305
methylation GO:0032259 106 0.305
response to other organism GO:0051707 261 0.304
gene silencing by rna GO:0031047 26 0.303
regulation of response to dna damage stimulus GO:2001020 94 0.298
striated muscle cell differentiation GO:0051146 43 0.297
negative regulation of bile acid biosynthetic process GO:0070858 3 0.296
regulation of viral process GO:0050792 103 0.296
ion homeostasis GO:0050801 230 0.291
Rat
inflammatory response GO:0006954 79 0.290
generation of precursor metabolites and energy GO:0006091 68 0.288
negative regulation by host of viral transcription GO:0043922 12 0.286
protein alkylation GO:0008213 74 0.286
interleukin 2 mediated signaling pathway GO:0038110 3 0.285
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.284
chemotaxis GO:0006935 157 0.284
response to metal ion GO:0010038 84 0.282
nucleoside triphosphate catabolic process GO:0009143 394 0.281
regulation of response to wounding GO:1903034 101 0.275
circulatory system process GO:0003013 113 0.274
regulation of cell cycle process GO:0010564 266 0.273
response to dexamethasone GO:0071548 1 0.270
secretion by tissue GO:0032941 9 0.270
placenta development GO:0001890 10 0.270
Rat
positive regulation of neurogenesis GO:0050769 49 0.269
rna splicing GO:0008380 131 0.262
endocrine system development GO:0035270 26 0.258
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.257
negative regulation of apoptotic signaling pathway GO:2001234 97 0.256
modulation by host of viral transcription GO:0043921 20 0.255
regulation of synaptic plasticity GO:0048167 3 0.254
histone demethylation GO:0016577 15 0.253

ESR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.510
disease of cellular proliferation DOID:14566 174 0.510
central nervous system disease DOID:331 186 0.413
nervous system disease DOID:863 431 0.413
disease of metabolism DOID:0014667 295 0.278
acquired metabolic disease DOID:0060158 58 0.278