Homo sapiens

50 known processes

EXOSC5

exosome component 5

(Aliases: MGC12901,MGC111224,RRP46,Rrp46p,p12B,RRP41B,hRrp46p)

EXOSC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
snrna metabolic process GO:0016073 15 1.000
ribonucleoprotein complex biogenesis GO:0022613 116 0.992
Yeast
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.982
Yeast
ncrna processing GO:0034470 83 0.975
Yeast
maturation of 5 8s rrna GO:0000460 8 0.973
Yeast
rrna processing GO:0006364 35 0.962
Yeast
rrna metabolic process GO:0016072 40 0.959
Yeast
ribosome biogenesis GO:0042254 48 0.923
Yeast
post embryonic development GO:0009791 2 0.893
Worm
ncrna metabolic process GO:0034660 108 0.873
Yeast
nuclear ncrna surveillance GO:0071029 2 0.815
Yeast
rrna catabolic process GO:0016075 6 0.781
Yeast
nuclear polyadenylation dependent rrna catabolic process GO:0071035 2 0.776
Yeast
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.732
Yeast Worm
cellular macromolecule catabolic process GO:0044265 380 0.672
nuclear polyadenylation dependent ncrna catabolic process GO:0071046 2 0.666
Yeast
trna catabolic process GO:0016078 1 0.645
Yeast
trna metabolic process GO:0006399 35 0.486
Yeast
cellular macromolecular complex assembly GO:0034622 324 0.486
nuclear rna surveillance GO:0071027 4 0.469
Yeast
nuclear transcribed mrna catabolic process GO:0000956 48 0.457
regulation of nucleoside metabolic process GO:0009118 209 0.446
mrna catabolic process GO:0006402 56 0.444
mrna metabolic process GO:0016071 175 0.437
polyadenylation dependent rna catabolic process GO:0043633 3 0.397
Yeast
polyadenylation dependent ncrna catabolic process GO:0043634 2 0.387
Yeast
regulation of gtp catabolic process GO:0033124 180 0.385
dna deamination GO:0045006 9 0.359
rna processing GO:0006396 255 0.332
Yeast Worm
endocytosis GO:0006897 159 0.331
vesicle mediated transport GO:0016192 371 0.308
rna phosphodiester bond hydrolysis GO:0090501 35 0.308
Yeast
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.288
Yeast
rna catabolic process GO:0006401 71 0.273
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.260
positive regulation of catabolic process GO:0009896 310 0.254
Worm
organophosphate catabolic process GO:0046434 430 0.228
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.225
cut metabolic process GO:0071043 3 0.202
regulation of nucleotide metabolic process GO:0006140 269 0.195
snrna processing GO:0016180 14 0.143
defense response to other organism GO:0098542 129 0.124
rna 3 end processing GO:0031123 35 0.114
Yeast
ncrna 3 end processing GO:0043628 4 0.112
Yeast
guanosine containing compound metabolic process GO:1901068 244 0.107
embryo development GO:0009790 123 0.093
gtp metabolic process GO:0046039 239 0.086
regulation of growth GO:0040008 165 0.070
ribonucleoprotein complex assembly GO:0022618 78 0.068
response to virus GO:0009615 126 0.064
amine metabolic process GO:0009308 44 0.061
defense response to virus GO:0051607 71 0.059
ncrna catabolic process GO:0034661 14 0.057
Yeast
regulation of cell growth GO:0001558 135 0.055
nucleoside triphosphate metabolic process GO:0009141 422 0.054
female gamete generation GO:0007292 2 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.051
response to external biotic stimulus GO:0043207 261 0.050
nucleoside triphosphate catabolic process GO:0009143 394 0.050
positive regulation of cellular catabolic process GO:0031331 284 0.048
Worm
dna catabolic process GO:0006308 49 0.048
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.047
dna catabolic process endonucleolytic GO:0000737 37 0.046
Worm
mitochondrion organization GO:0007005 156 0.045
cellular amino acid metabolic process GO:0006520 116 0.044
cell growth GO:0016049 160 0.044
cellular ketone metabolic process GO:0042180 80 0.044
negative regulation of catalytic activity GO:0043086 335 0.043
dna modification GO:0006304 27 0.042
glycerolipid metabolic process GO:0046486 107 0.039
blastocyst formation GO:0001825 3 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.037
determination of adult lifespan GO:0008340 2 0.036
Worm
ribonucleoside catabolic process GO:0042454 406 0.035
growth GO:0040007 202 0.035
multicellular organismal aging GO:0010259 3 0.035
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.034
protein maturation GO:0051604 233 0.033
positive regulation of growth GO:0045927 58 0.032
response to biotic stimulus GO:0009607 276 0.032
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
regulation of gene expression epigenetic GO:0040029 73 0.027
response to other organism GO:0051707 261 0.027
cellular amine metabolic process GO:0044106 41 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.026
modification dependent macromolecule catabolic process GO:0043632 212 0.026
Yeast
regulation of generation of precursor metabolites and energy GO:0043467 27 0.026
regulation of gtpase activity GO:0043087 180 0.025
ion homeostasis GO:0050801 230 0.024
guanosine containing compound catabolic process GO:1901069 239 0.024
snorna metabolic process GO:0016074 1 0.024
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
system process GO:0003008 349 0.022
establishment of protein localization to membrane GO:0090150 121 0.021
cellular response to organic cyclic compound GO:0071407 127 0.021
embryo development ending in birth or egg hatching GO:0009792 34 0.020
defense response GO:0006952 315 0.020
receptor mediated endocytosis GO:0006898 84 0.020
glycerophospholipid metabolic process GO:0006650 84 0.019
gtp catabolic process GO:0006184 237 0.019
protein oligomerization GO:0051259 173 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
chemical homeostasis GO:0048878 306 0.019
cellular lipid metabolic process GO:0044255 303 0.019
cellular protein complex assembly GO:0043623 188 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
positive regulation of cell growth GO:0030307 48 0.018
immune response GO:0006955 307 0.018
cellular homeostasis GO:0019725 196 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
negative regulation of cell death GO:0060548 345 0.017
cut catabolic process GO:0071034 3 0.017
innate immune response GO:0045087 178 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
regulation of feeding behavior GO:0060259 3 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
cytoplasmic transport GO:0016482 379 0.016
organelle assembly GO:0070925 176 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
regulation of defense response GO:0031347 154 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of hydrolase activity GO:0051345 331 0.015
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
mitochondrial transport GO:0006839 60 0.015
purine ribonucleotide biosynthetic process GO:0009152 79 0.014
protein localization to membrane GO:0072657 160 0.014
maintenance of location GO:0051235 112 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
negative regulation of transferase activity GO:0051348 124 0.014
transmembrane transport GO:0055085 399 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
regulation of membrane potential GO:0042391 95 0.014
immune effector process GO:0002252 159 0.014
single organism membrane organization GO:0044802 268 0.014
negative regulation of protein kinase activity GO:0006469 98 0.013
membrane organization GO:0061024 292 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
rna surveillance GO:0071025 5 0.013
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.013
neurological system process GO:0050877 163 0.013
cation transmembrane transport GO:0098655 238 0.013
phospholipid metabolic process GO:0006644 99 0.013
blastocyst development GO:0001824 3 0.013
single organism reproductive process GO:0044702 98 0.012
negative regulation of protein modification process GO:0031400 200 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of cellular response to stress GO:0080135 244 0.012
nuclear transport GO:0051169 179 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
nucleotide catabolic process GO:0009166 408 0.012
rna interference GO:0016246 4 0.012
purine containing compound catabolic process GO:0072523 411 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
response to oxygen containing compound GO:1901700 369 0.011
dna repair GO:0006281 198 0.011
protein targeting GO:0006605 187 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
mitotic cell cycle GO:0000278 326 0.011
cellular component disassembly GO:0022411 92 0.011
Worm
regulation of apoptotic signaling pathway GO:2001233 175 0.010
protein import GO:0017038 130 0.010
negative regulation of immune system process GO:0002683 136 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
regulation of protein localization GO:0032880 296 0.010
regulation of cell cycle GO:0051726 393 0.010
lipid metabolic process GO:0006629 381 0.010

EXOSC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.095
inherited metabolic disorder DOID:655 242 0.041