Homo sapiens

62 known processes

EXOSC9

exosome component 9

(Aliases: p6,PM/Scl-75,p5,Rrp45p,RRP45,PMSCL1)

EXOSC9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.996
Yeast
snrna metabolic process GO:0016073 15 0.987
Yeast
nuclear ncrna surveillance GO:0071029 2 0.956
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.951
polyadenylation dependent rna catabolic process GO:0043633 3 0.901
rna phosphodiester bond hydrolysis GO:0090501 35 0.877
Yeast
snrna processing GO:0016180 14 0.867
Yeast
nuclear polyadenylation dependent ncrna catabolic process GO:0071046 2 0.820
organophosphate catabolic process GO:0046434 430 0.792
rna 3 end processing GO:0031123 35 0.758
Yeast
trna catabolic process GO:0016078 1 0.753
Yeast
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.723
glycosyl compound catabolic process GO:1901658 413 0.686
nuclear polyadenylation dependent rrna catabolic process GO:0071035 2 0.670
rna processing GO:0006396 255 0.657
Yeast
purine ribonucleoside catabolic process GO:0046130 398 0.613
determination of adult lifespan GO:0008340 2 0.551
ncrna catabolic process GO:0034661 14 0.536
nuclear rna surveillance GO:0071027 4 0.531
maturation of 5 8s rrna GO:0000460 8 0.502
Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.492
nucleoside phosphate catabolic process GO:1901292 412 0.485
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.367
Yeast
purine containing compound catabolic process GO:0072523 411 0.364
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.342
Yeast
mrna metabolic process GO:0016071 175 0.311
post embryonic development GO:0009791 2 0.269
Worm
gtp metabolic process GO:0046039 239 0.264
purine nucleotide catabolic process GO:0006195 405 0.263
rrna metabolic process GO:0016072 40 0.259
ribonucleoside catabolic process GO:0042454 406 0.254
polyadenylation dependent ncrna catabolic process GO:0043634 2 0.254
rna catabolic process GO:0006401 71 0.251
ribonucleoside triphosphate metabolic process GO:0009199 412 0.250
ribosome biogenesis GO:0042254 48 0.244
Yeast
multicellular organismal aging GO:0010259 3 0.233
purine nucleoside catabolic process GO:0006152 398 0.208
mitotic cell cycle process GO:1903047 286 0.203
intracellular mrna localization GO:0008298 1 0.200
positive regulation of catabolic process GO:0009896 310 0.198
cut metabolic process GO:0071043 3 0.193
guanosine containing compound metabolic process GO:1901068 244 0.190
rna surveillance GO:0071025 5 0.185
rrna processing GO:0006364 35 0.174
Yeast
snrna 3 end processing GO:0034472 1 0.171
Yeast
defense response to other organism GO:0098542 129 0.167
mrna catabolic process GO:0006402 56 0.165
nucleoside triphosphate catabolic process GO:0009143 394 0.162
nuclear mrna surveillance GO:0071028 4 0.161
purine nucleoside triphosphate catabolic process GO:0009146 392 0.156
ribonucleoside triphosphate catabolic process GO:0009203 391 0.153
ribonucleoprotein complex biogenesis GO:0022613 116 0.152
Yeast
ribonucleotide catabolic process GO:0009261 405 0.142
ncrna metabolic process GO:0034660 108 0.140
vesicle mediated transport GO:0016192 371 0.120
regulation of cell cycle GO:0051726 393 0.119
regulation of mitotic cell cycle GO:0007346 189 0.116
cellular macromolecule catabolic process GO:0044265 380 0.116
response to external biotic stimulus GO:0043207 261 0.113
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.110
dna catabolic process endonucleolytic GO:0000737 37 0.108
purine ribonucleotide catabolic process GO:0009154 404 0.108
positive regulation of cellular catabolic process GO:0031331 284 0.105
mitotic cell cycle GO:0000278 326 0.103
positive regulation of hydrolase activity GO:0051345 331 0.102
purine nucleoside monophosphate catabolic process GO:0009128 158 0.101
nucleotide catabolic process GO:0009166 408 0.091
regulation of cell growth GO:0001558 135 0.089
cellular component disassembly GO:0022411 92 0.086
dna modification GO:0006304 27 0.081
cell growth GO:0016049 160 0.081
purine ribonucleoside metabolic process GO:0046128 437 0.077
embryo development GO:0009790 123 0.069
Worm
microtubule cytoskeleton organization GO:0000226 176 0.067
enzyme linked receptor protein signaling pathway GO:0007167 303 0.066
endocytosis GO:0006897 159 0.064
regulation of nucleoside metabolic process GO:0009118 209 0.064
rna localization GO:0006403 41 0.063
purine nucleoside triphosphate metabolic process GO:0009144 412 0.061
rrna catabolic process GO:0016075 6 0.060
ncrna 3 end processing GO:0043628 4 0.056
Yeast
small gtpase mediated signal transduction GO:0007264 78 0.055
microtubule based process GO:0007017 210 0.053
positive regulation of gtp catabolic process GO:0033126 166 0.053
regulation of cell cycle process GO:0010564 266 0.053
guanosine containing compound catabolic process GO:1901069 239 0.053
cellular macromolecular complex assembly GO:0034622 324 0.052
response to other organism GO:0051707 261 0.051
regulation of growth GO:0040008 165 0.049
nervous system development GO:0007399 293 0.049
negative regulation of cell cycle process GO:0010948 121 0.048
nucleoside catabolic process GO:0009164 408 0.047
negative regulation of protein metabolic process GO:0051248 391 0.046
chromatin organization GO:0006325 351 0.045
chromatin modification GO:0016568 298 0.045
gtp catabolic process GO:0006184 237 0.044
nucleoside triphosphate metabolic process GO:0009141 422 0.044
positive regulation of nucleotide metabolic process GO:0045981 230 0.043
receptor mediated endocytosis GO:0006898 84 0.042
regulation of cellular response to stress GO:0080135 244 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.041
mitotic nuclear division GO:0007067 119 0.041
protein localization to nucleus GO:0034504 136 0.040
positive regulation of mapk cascade GO:0043410 190 0.040
regulation of nucleotide metabolic process GO:0006140 269 0.040
neurological system process GO:0050877 163 0.039
histone mrna metabolic process GO:0008334 13 0.039
nucleoside monophosphate catabolic process GO:0009125 159 0.039
system process GO:0003008 349 0.038
negative regulation of cell cycle GO:0045786 193 0.037
intracellular protein transport GO:0006886 270 0.036
regulation of gtp catabolic process GO:0033124 180 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
positive regulation of gtpase activity GO:0043547 166 0.035
protein localization to organelle GO:0033365 280 0.035
positive regulation of cell growth GO:0030307 48 0.035
growth GO:0040007 202 0.035
protein targeting to nucleus GO:0044744 104 0.034
positive regulation of transport GO:0051050 336 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
modification dependent protein catabolic process GO:0019941 209 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.033
defense response GO:0006952 315 0.033
response to biotic stimulus GO:0009607 276 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.032
single organism cellular localization GO:1902580 332 0.031
regulation of protein catabolic process GO:0042176 155 0.031
immune effector process GO:0002252 159 0.030
ubiquitin dependent protein catabolic process GO:0006511 206 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
positive regulation of nucleoside metabolic process GO:0045979 186 0.029
regulation of cellular component movement GO:0051270 334 0.029
nuclear transport GO:0051169 179 0.028
cell cell signaling GO:0007267 155 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
mitotic cell cycle phase transition GO:0044772 162 0.027
polyadenylation dependent mrna catabolic process GO:0071047 1 0.027
regulation of gtpase activity GO:0043087 180 0.027
positive regulation of cell death GO:0010942 263 0.027
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
cellular protein complex assembly GO:0043623 188 0.026
segmentation GO:0035282 4 0.026
negative regulation of cell cycle phase transition GO:1901988 89 0.025
neurogenesis GO:0022008 169 0.025
chromosome segregation GO:0007059 114 0.025
positive regulation of growth GO:0045927 58 0.025
cell development GO:0048468 328 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.025
snorna metabolic process GO:0016074 1 0.025
regulation of transferase activity GO:0051338 355 0.025
response to virus GO:0009615 126 0.024
covalent chromatin modification GO:0016569 254 0.024
cardiac muscle cell contraction GO:0086003 4 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
response to cytokine GO:0034097 232 0.023
actin filament based process GO:0030029 224 0.023
negative regulation of mitotic cell cycle GO:0045930 102 0.023
regulation of protein stability GO:0031647 87 0.022
regulation of mapk cascade GO:0043408 262 0.022
peptidyl lysine modification GO:0018205 144 0.022
protein processing GO:0016485 226 0.022
cytoplasmic transport GO:0016482 379 0.021
positive regulation of cell cycle GO:0045787 140 0.021
nitrogen compound transport GO:0071705 191 0.021
sister chromatid segregation GO:0000819 54 0.021
regulation of mitosis GO:0007088 63 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
protein import into nucleus GO:0006606 104 0.021
dna catabolic process GO:0006308 49 0.021
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
single organism nuclear import GO:1902593 104 0.021
mitotic sister chromatid segregation GO:0000070 53 0.021
regeneration GO:0031099 4 0.021
protein import GO:0017038 130 0.021
regulation of locomotion GO:0040012 329 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
regulation of mitotic cell cycle phase transition GO:1901990 118 0.020
multicellular organismal signaling GO:0035637 34 0.020
histone modification GO:0016570 251 0.020
nuclear import GO:0051170 106 0.020
regulation of proteolysis GO:0030162 293 0.020
positive regulation of locomotion GO:0040017 186 0.020
cellular response to cytokine stimulus GO:0071345 181 0.019
cardiovascular system development GO:0072358 262 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
regulation of dna metabolic process GO:0051052 153 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.018
regulation of meiosis GO:0040020 3 0.018
cell adhesion GO:0007155 325 0.018
protein catabolic process GO:0030163 325 0.018
oogenesis GO:0048477 2 0.018
biological adhesion GO:0022610 331 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
cell cycle checkpoint GO:0000075 117 0.018
ras protein signal transduction GO:0007265 73 0.018
regulation of cell cycle phase transition GO:1901987 126 0.017
amine metabolic process GO:0009308 44 0.017
locomotory behavior GO:0007626 1 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
positive regulation of cytoplasmic transport GO:1903651 82 0.017
response to radiation GO:0009314 151 0.017
trna metabolic process GO:0006399 35 0.017
Yeast
peptidyl serine modification GO:0018209 106 0.017
adult locomotory behavior GO:0008344 1 0.016
cellular amine metabolic process GO:0044106 41 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
positive regulation of cell cycle process GO:0090068 106 0.016
protein autophosphorylation GO:0046777 123 0.016
nuclear division GO:0000280 128 0.016
atp catabolic process GO:0006200 157 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
dephosphorylation GO:0016311 209 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
cardiac muscle contraction GO:0060048 34 0.016
positive regulation of transferase activity GO:0051347 227 0.015
negative regulation of cell death GO:0060548 345 0.015
embryo development ending in birth or egg hatching GO:0009792 34 0.015
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
response to abiotic stimulus GO:0009628 336 0.015
regulation of intracellular transport GO:0032386 195 0.015
cut catabolic process GO:0071034 3 0.015
erk1 and erk2 cascade GO:0070371 104 0.015
meiotic chromosome segregation GO:0045132 4 0.015
regulation of chromosome organization GO:0033044 103 0.015
dna integrity checkpoint GO:0031570 71 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
internal peptidyl lysine acetylation GO:0018393 97 0.015
protein ubiquitination GO:0016567 314 0.015
protein maturation GO:0051604 233 0.015
regulation of protein localization GO:0032880 296 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
aging GO:0007568 66 0.015
positive regulation of protein transport GO:0051222 135 0.015
maintenance of location GO:0051235 112 0.014
response to oxygen containing compound GO:1901700 369 0.014
protein targeting GO:0006605 187 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
negative regulation of protein modification process GO:0031400 200 0.014
protein stabilization GO:0050821 64 0.014
histone acetylation GO:0016573 93 0.014
positive regulation of nfat protein import into nucleus GO:0051533 3 0.014
muscle system process GO:0003012 81 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
behavior GO:0007610 112 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
female gamete generation GO:0007292 2 0.013
organelle fission GO:0048285 149 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
reproductive process GO:0022414 106 0.013
regulation of protein transport GO:0051223 213 0.013
cell division GO:0051301 168 0.013
developmental process involved in reproduction GO:0003006 66 0.013
ncrna processing GO:0034470 83 0.013
Yeast
generation of neurons GO:0048699 152 0.013
vasculature development GO:0001944 181 0.013
endomembrane system organization GO:0010256 196 0.013
muscle contraction GO:0006936 73 0.013
reproductive system development GO:0061458 56 0.013
reproduction GO:0000003 63 0.013
Worm
response to growth factor GO:0070848 205 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
protein acylation GO:0043543 138 0.013
rna splicing GO:0008380 131 0.012
nuclear polyadenylation dependent mrna catabolic process GO:0071042 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
cell cycle phase transition GO:0044770 173 0.012
regulation of cytokine production GO:0001817 232 0.012
regulation of cell differentiation GO:0045595 393 0.012
cellular amino acid metabolic process GO:0006520 116 0.012
cell projection organization GO:0030030 252 0.012
regulation of cell motility GO:2000145 299 0.012
immune response GO:0006955 307 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
nuclear migration GO:0007097 1 0.012
protein dna complex subunit organization GO:0071824 80 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
regulation of kinase activity GO:0043549 314 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
regulation of cellular response to growth factor stimulus GO:0090287 76 0.011
negative regulation of protein processing GO:0010955 142 0.011
cytokine production GO:0001816 247 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
cellular response to oxidative stress GO:0034599 85 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
actin filament based movement GO:0030048 17 0.010
negative regulation of catabolic process GO:0009895 104 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
regulation of cardiac muscle contraction GO:0055117 33 0.010
organelle assembly GO:0070925 176 0.010
protein oligomerization GO:0051259 173 0.010
regulation of cellular ketone metabolic process GO:0010565 50 0.010
mrna processing GO:0006397 133 0.010
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.010
regulation of cellular component biogenesis GO:0044087 281 0.010

EXOSC9 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.014
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
organ system cancer DOID:0050686 164 0.011
inherited metabolic disorder DOID:655 242 0.010