|
|
modified amino acid transport
|
GO:0072337 |
11 |
0.999
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.979
|
Mouse Fly |
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.950
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.922
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.920
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.907
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.893
|
Human |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.850
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.824
|
Human |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.790
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.771
|
Worm |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.770
|
Mouse Worm Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.758
|
Worm |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.737
|
Mouse Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.729
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.709
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.709
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.695
|
Worm |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.692
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.688
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.682
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.681
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.679
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.655
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.654
|
Human |
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.654
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.621
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.620
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.615
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.610
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.609
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.609
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.598
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.595
|
Worm Fly |
|
|
amino acid betaine transport
|
GO:0015838 |
4 |
0.590
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.588
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.585
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.576
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.574
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.574
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.571
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.565
|
Worm |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.557
|
Fly |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.553
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.546
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.531
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.531
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
14 |
0.521
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.515
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.513
|
Fly |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.508
|
Worm |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.507
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.505
|
Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.493
|
Worm Fly |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.485
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.485
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.485
|
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.484
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.481
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.479
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.466
|
Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.466
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.464
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.455
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.454
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.448
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.438
|
Human |
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.438
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.437
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.437
|
Human Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.435
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.428
|
Worm |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.424
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.413
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.404
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.394
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.387
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.385
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.381
|
Human Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.377
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.375
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.371
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.360
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.356
|
Fly |
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.345
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.343
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.342
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.335
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.334
|
Worm |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.330
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.329
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.328
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.323
|
Worm |
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.319
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.315
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.314
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.310
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.309
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.309
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.309
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.309
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.308
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.303
|
Human Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.303
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.300
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.298
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.296
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.294
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.294
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.290
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.283
|
Human Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.278
|
|
|
|
cellular phosphate ion homeostasis
|
GO:0030643 |
4 |
0.274
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.273
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.272
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.272
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.269
|
Human |
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.264
|
Human |
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.261
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.260
|
Fly |
|
|
regulation of excretion
|
GO:0044062 |
1 |
0.259
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.257
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.256
|
Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.256
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.255
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.250
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.248
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.246
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.244
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.244
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.243
|
Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.243
|
Human |
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.242
|
Human |
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.239
|
|
|
|
negative regulation of cgmp metabolic process
|
GO:0030824 |
1 |
0.238
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.237
|
Fly |
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.236
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.234
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.234
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.233
|
Fly |
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.232
|
|
|
|
regulation of sodium proton antiporter activity
|
GO:0032415 |
3 |
0.232
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.232
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.231
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.230
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.229
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.228
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.226
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.223
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.221
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.218
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.217
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.216
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.212
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.210
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.210
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.205
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.204
|
Fly |
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.204
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.202
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.200
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.200
|
|
|
|
trivalent inorganic anion homeostasis
|
GO:0072506 |
7 |
0.195
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.190
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.187
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.186
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.186
|
Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.185
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.185
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.184
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.184
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.181
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.181
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.175
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.174
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.174
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.171
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.169
|
Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.169
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.167
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.167
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.165
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.161
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.161
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.161
|
Human |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.158
|
Human |
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
11 |
0.158
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.158
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.156
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.155
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.155
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.154
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
2 |
0.153
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.151
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.151
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.150
|
|
|
|
hydrogen transport
|
GO:0006818 |
23 |
0.149
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.146
|
Fly |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.145
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.144
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.143
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.142
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.140
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.140
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.138
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.137
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.137
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.137
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.135
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.134
|
Worm Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.133
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.132
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.132
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.131
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.130
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.130
|
Fly |
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.130
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.129
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.128
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.128
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.127
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.127
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.126
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.125
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.125
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.125
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.124
|
Worm Fly |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.122
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.121
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.121
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.120
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.120
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.119
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.117
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.116
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.114
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.113
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.113
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.112
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.112
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.112
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.111
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.111
|
Rat Fly |
|
|
vasodilation
|
GO:0042311 |
4 |
0.111
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.111
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.111
|
Rat |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.111
|
Human |
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.110
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.110
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.109
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.109
|
Zebrafish |
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.109
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.108
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.108
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.108
|
Fly |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.106
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.106
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.105
|
Zebrafish Worm Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.105
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.102
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.102
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.102
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.100
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.100
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.100
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.100
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.099
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.099
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.099
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.099
|
Worm |
|
|
growth
|
GO:0040007 |
202 |
0.098
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.097
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.097
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.096
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.096
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.096
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.095
|
Human Fly |
|
|
phosphate ion homeostasis
|
GO:0055062 |
7 |
0.095
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.095
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.093
|
|
|
|
negative regulation of lyase activity
|
GO:0051350 |
7 |
0.093
|
|
|
|
microvillus assembly
|
GO:0030033 |
2 |
0.093
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.092
|
Human Fly |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.092
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.091
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.090
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.090
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.090
|
Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.090
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.088
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.088
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.086
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.086
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.085
|
Fly |
|
|
spindle organization
|
GO:0007051 |
53 |
0.085
|
Fly |
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.085
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.085
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.084
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.083
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.083
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.083
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.082
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.082
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.082
|
Human |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.082
|
|
|
|
cellular divalent inorganic anion homeostasis
|
GO:0072501 |
4 |
0.081
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.080
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.080
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.080
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.080
|
Fly |
|
|
sensory perception
|
GO:0007600 |
103 |
0.080
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.080
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.080
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.080
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.079
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.079
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.079
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.079
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.079
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.078
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.078
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.078
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.077
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.077
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.076
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.075
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.074
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.073
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.072
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.072
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.072
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.072
|
Fly |
|
|
assembly of actomyosin apparatus involved in cytokinesis
|
GO:0000912 |
1 |
0.070
|
Fly |
|
|
cellular anion homeostasis
|
GO:0030002 |
4 |
0.070
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.069
|
Human |
|
|
regulation of leukocyte cell cell adhesion
|
GO:1903037 |
7 |
0.069
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.068
|
Worm |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.068
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.068
|
Zebrafish Worm |
|
|
negative regulation of cyclase activity
|
GO:0031280 |
6 |
0.067
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.066
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.066
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.066
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.066
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.066
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.066
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.066
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.065
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.065
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.065
|
Zebrafish Worm |
|
|
taxis
|
GO:0042330 |
157 |
0.064
|
Fly |
|
|
glial cell proliferation
|
GO:0014009 |
6 |
0.064
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.064
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.063
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.063
|
Fly |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.062
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.062
|
Fly |
|
|
lipid transport
|
GO:0006869 |
90 |
0.062
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.062
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.062
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.062
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.062
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.062
|
Fly |
|
|
hemostasis
|
GO:0007599 |
76 |
0.061
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
10 |
0.061
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.061
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.061
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.061
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.061
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.061
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.060
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.060
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.060
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.060
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.060
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.060
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.059
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.059
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.059
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.058
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.058
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.058
|
Human |
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.058
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.058
|
Fly |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.057
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.057
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.057
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.057
|
|
|
|
aging
|
GO:0007568 |
66 |
0.057
|
Worm |
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.057
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.057
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.057
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.056
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.056
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.056
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.056
|
Fly |
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.056
|
|
|
|
mating
|
GO:0007618 |
1 |
0.056
|
Fly |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.056
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.055
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.055
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.055
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.055
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.055
|
Human |
|
|
microvillus organization
|
GO:0032528 |
2 |
0.055
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.055
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.055
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.055
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.054
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.054
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.053
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.053
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.053
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.053
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.053
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.053
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.053
|
Worm |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.052
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.052
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.052
|
Fly |
|
|
amino acid transport
|
GO:0006865 |
28 |
0.052
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.052
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.052
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.052
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.051
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.051
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.051
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.051
|
Human Worm |
|
|
lung associated mesenchyme development
|
GO:0060484 |
1 |
0.051
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.051
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.051
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.051
|
Human |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.051
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.050
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.050
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.050
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.050
|
Human |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.049
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.049
|
Fly |
|
|
neuron development
|
GO:0048666 |
113 |
0.048
|
Fly |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.048
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.048
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.048
|
Fly |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.048
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.048
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.048
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.048
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.048
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.048
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.048
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.048
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.048
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.047
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.047
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.047
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.047
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.046
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.046
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.046
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.046
|
Fly |
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.046
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.046
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.045
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.045
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.044
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.044
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.044
|
|
|
|
memory
|
GO:0007613 |
3 |
0.044
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.044
|
Fly |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.044
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.044
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.044
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.044
|
Worm |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.043
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.043
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.043
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.043
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.043
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.043
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.043
|
|
