|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.923
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.878
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.757
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.750
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.691
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.665
|
|
|
|
negative regulation of acute inflammatory response
|
GO:0002674 |
3 |
0.630
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.596
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.594
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.590
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.564
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.542
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.537
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.514
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.509
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.483
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.477
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.465
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.459
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.456
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.441
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.426
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.417
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.415
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.397
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.395
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.394
|
|
|
|
positive regulation of muscle hypertrophy
|
GO:0014742 |
6 |
0.385
|
|
|
|
activation of protein kinase b activity
|
GO:0032148 |
14 |
0.373
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.372
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.365
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.354
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.338
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.328
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.321
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.313
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.312
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.304
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.301
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.300
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.295
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.278
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.275
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.264
|
|
|
|
cellular polysaccharide catabolic process
|
GO:0044247 |
4 |
0.263
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.258
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.253
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.251
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.251
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.242
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.235
|
|
|
|
system process
|
GO:0003008 |
349 |
0.234
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.232
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.229
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.228
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.227
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.222
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.220
|
|
|
|
positive regulation of calcineurin nfat signaling cascade
|
GO:0070886 |
4 |
0.220
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.219
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.216
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.215
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.211
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.210
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.210
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.207
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.206
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
9 |
0.204
|
|
|
|
regulation of glycogen catabolic process
|
GO:0005981 |
2 |
0.204
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.203
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.202
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.197
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.196
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.190
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.187
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.184
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.184
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.178
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.175
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.174
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.174
|
|
|
|
bone mineralization involved in bone maturation
|
GO:0035630 |
3 |
0.172
|
|
|
|
myoblast proliferation
|
GO:0051450 |
1 |
0.170
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.168
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.164
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.159
|
|
|
|
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
|
GO:0002043 |
3 |
0.158
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.157
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.157
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.155
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.154
|
|
|
|
negative regulation of feeding behavior
|
GO:2000252 |
1 |
0.151
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.151
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.150
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.150
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.148
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.146
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.145
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.143
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.140
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.139
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.139
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.138
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.138
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.137
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.137
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.137
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.136
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.135
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.133
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.133
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.133
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.132
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.130
|
|
|
|
fatty acid homeostasis
|
GO:0055089 |
3 |
0.129
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.128
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.128
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.128
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.127
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.126
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.125
|
|
|
|
negative regulation of substrate adhesion dependent cell spreading
|
GO:1900025 |
4 |
0.125
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.123
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.123
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.122
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.119
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.117
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.116
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.116
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.115
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.113
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.113
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.110
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.108
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.108
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.107
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.104
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.100
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.099
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.098
|
Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.098
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.097
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.097
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.097
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.097
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.097
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.096
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.096
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.096
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.096
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.095
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.091
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.088
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.087
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.086
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.086
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.085
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.084
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.084
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.083
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.083
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.083
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.082
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.081
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.081
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.080
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.080
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.079
|
|
|
|
memory
|
GO:0007613 |
3 |
0.078
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.077
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.076
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.075
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.074
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.074
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.074
|
|
|
|
positive regulation of steroid metabolic process
|
GO:0045940 |
13 |
0.073
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.073
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.072
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.072
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.072
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.071
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.071
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.070
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.070
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.070
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.069
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.069
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.068
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.067
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.067
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.066
|
Mouse |
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.065
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
4 |
0.065
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.065
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.064
|
Fly |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.063
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.063
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.062
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.062
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.061
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.061
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.061
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.061
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.061
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.061
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.061
|
Fly |
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.060
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.059
|
Mouse |
|
|
gonad development
|
GO:0008406 |
34 |
0.059
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.059
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.059
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.058
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.058
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.058
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.057
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.057
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.057
|
|
|
|
organ maturation
|
GO:0048799 |
5 |
0.056
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.056
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.055
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.055
|
|
|
|
acute phase response
|
GO:0006953 |
5 |
0.055
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.055
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.055
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.055
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.054
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.054
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.054
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.053
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.053
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.053
|
|
|
|
porphyrin containing compound metabolic process
|
GO:0006778 |
10 |
0.053
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.053
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.053
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.052
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.052
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.051
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.051
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.051
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.051
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.050
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.050
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
24 |
0.050
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.050
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.049
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.049
|
|
|
|
thioester metabolic process
|
GO:0035383 |
23 |
0.049
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.048
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.048
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.048
|
|
|
|
translation
|
GO:0006412 |
132 |
0.047
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.047
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.046
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.045
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.045
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.045
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.045
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.044
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.044
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.044
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.044
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.044
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.044
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.043
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.043
|
Fly |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.043
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.043
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.043
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.043
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.043
|
|
|
|
pronephros development
|
GO:0048793 |
2 |
0.042
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.042
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.042
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.042
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.042
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.042
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.042
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.042
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.042
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.041
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.041
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.041
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.041
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.041
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.040
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.040
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.040
|
|
|
|
regulation of cdc42 gtpase activity
|
GO:0043088 |
10 |
0.040
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.040
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.039
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.038
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.038
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.038
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.038
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.038
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
29 |
0.038
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.038
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.038
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.038
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.038
|
|
|
|
bone maturation
|
GO:0070977 |
5 |
0.037
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.037
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.037
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.037
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
11 |
0.037
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.037
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.036
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.036
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.036
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.036
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.036
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.036
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.035
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.035
|
|
|
|
negative regulation of cell junction assembly
|
GO:1901889 |
5 |
0.035
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.035
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.034
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.034
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.034
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.034
|
Fly |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.034
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.034
|
|
|
|
positive regulation of cardiac muscle hypertrophy
|
GO:0010613 |
6 |
0.034
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.033
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.033
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.033
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.033
|
|
|
|
proteoglycan biosynthetic process
|
GO:0030166 |
20 |
0.033
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.033
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.033
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.033
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.032
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.032
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.032
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.032
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.032
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.032
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.032
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.032
|
|
|
|
regulation of insulin like growth factor receptor signaling pathway
|
GO:0043567 |
8 |
0.032
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.032
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.032
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.031
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.031
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.031
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.031
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.031
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.031
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.031
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.030
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.030
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.030
|
Fly |
|
|
protein processing
|
GO:0016485 |
226 |
0.030
|
Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.030
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.030
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.030
|
|
|
|
growth
|
GO:0040007 |
202 |
0.030
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.030
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.030
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.029
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.029
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.029
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.029
|
|
|
|
regulation of respiratory burst
|
GO:0060263 |
8 |
0.029
|
|
|
|
negative regulation of glycogen metabolic process
|
GO:0070874 |
4 |
0.028
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.028
|
|
|
|
pigment biosynthetic process
|
GO:0046148 |
10 |
0.028
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.028
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.027
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.027
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.027
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.027
|
|
|
|
heme metabolic process
|
GO:0042168 |
8 |
0.027
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.026
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.026
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.026
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.026
|
|
|
|
hexose transport
|
GO:0008645 |
30 |
0.026
|
|
|
|
head development
|
GO:0060322 |
108 |
0.026
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.025
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.025
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.025
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.025
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.025
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.025
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.025
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.025
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.025
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.024
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.024
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.024
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.024
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
16 |
0.024
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.024
|
Fly |
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.024
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.024
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.024
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.024
|
|
|
|
negative regulation of smooth muscle cell apoptotic process
|
GO:0034392 |
3 |
0.024
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.024
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.023
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.023
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.023
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.023
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.023
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.023
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.022
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.022
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.022
|
|
|
|
positive regulation of hormone metabolic process
|
GO:0032352 |
6 |
0.022
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.022
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.022
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.022
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.022
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.022
|
|
|
|
cellular response to misfolded protein
|
GO:0071218 |
2 |
0.021
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.021
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
|
|
|
polysaccharide catabolic process
|
GO:0000272 |
4 |
0.021
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.021
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.021
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
14 |
0.021
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
16 |
0.021
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.021
|
Fly |
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.021
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.021
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.020
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.020
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.020
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.020
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.020
|
|
|
|
aging
|
GO:0007568 |
66 |
0.020
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.020
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.020
|
Mouse |
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.020
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.020
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.020
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.020
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.020
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.020
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.020
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.019
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.019
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.019
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.019
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.019
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.019
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.019
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.019
|
|
|
|
negative regulation of cell migration involved in sprouting angiogenesis
|
GO:0090051 |
6 |
0.019
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.019
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.019
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.019
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.019
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.019
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.019
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.019
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.019
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.019
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.018
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.018
|
Fly |
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.018
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.018
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.018
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.018
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.018
|
|
|
|
negative regulation of adherens junction organization
|
GO:1903392 |
5 |
0.018
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.018
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.018
|
Mouse |
|
|
glycolytic process
|
GO:0006096 |
17 |
0.018
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.018
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.018
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.018
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.018
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.018
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.018
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.018
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.017
|
|
