Homo sapiens

15 known processes

FANCD2

Fanconi anemia, complementation group D2

(Aliases: FAD2,DKFZp762A223,FLJ23826,FACD,FANCD,FA4,FAD,FA-D2)

FANCD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via homologous recombination GO:0000724 50 0.999
double strand break repair GO:0006302 101 0.991
dna double strand break processing GO:0000729 10 0.983
g2 dna damage checkpoint GO:0031572 26 0.975
telomere capping GO:0016233 5 0.966
dna recombination GO:0006310 77 0.941
nucleotide excision repair GO:0006289 31 0.938
regulation of protein autophosphorylation GO:0031952 15 0.936
anatomical structure homeostasis GO:0060249 100 0.925
dna damage induced protein phosphorylation GO:0006975 5 0.899
replication fork processing GO:0031297 13 0.874
double strand break repair via single strand annealing GO:0045002 4 0.861
telomere maintenance via recombination GO:0000722 4 0.844
cell cycle checkpoint GO:0000075 117 0.829
cellular response to dna damage stimulus GO:0006974 379 0.829
Mouse
dna repair GO:0006281 198 0.799
recombinational repair GO:0000725 50 0.769
purine nucleoside triphosphate metabolic process GO:0009144 412 0.754
oocyte differentiation GO:0009994 2 0.748
intrinsic apoptotic signaling pathway GO:0097193 127 0.726
regulation of cellular response to stress GO:0080135 244 0.711
covalent chromatin modification GO:0016569 254 0.708
telomere maintenance via telomere lengthening GO:0010833 9 0.706
response to gamma radiation GO:0010332 14 0.696
dna damage checkpoint GO:0000077 68 0.694
response to radiation GO:0009314 151 0.687
blastocyst development GO:0001824 3 0.661
g2 m transition of mitotic cell cycle GO:0000086 41 0.657
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.608
male meiosis GO:0007140 1 0.550
oocyte maturation GO:0001556 1 0.540
positive regulation of transferase activity GO:0051347 227 0.507
dna geometric change GO:0032392 32 0.507
regulation of mitotic cell cycle GO:0007346 189 0.507
telomere maintenance GO:0000723 32 0.492
dna integrity checkpoint GO:0031570 71 0.476
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.463
protein modification by small protein conjugation GO:0032446 342 0.463
regulation of transferase activity GO:0051338 355 0.463
regulation of meiotic cell cycle GO:0051445 4 0.445
meiotic chromosome segregation GO:0045132 4 0.431
positive regulation of kinase activity GO:0033674 204 0.420
chromatin modification GO:0016568 298 0.414
postreplication repair GO:0006301 12 0.411
dna catabolic process exonucleolytic GO:0000738 17 0.402
oocyte development GO:0048599 1 0.381
telomere organization GO:0032200 33 0.377
signal transduction in response to dna damage GO:0042770 57 0.372
regulation of dna metabolic process GO:0051052 153 0.368
signal transduction by phosphorylation GO:0023014 297 0.363
response to uv GO:0009411 73 0.358
development of primary male sexual characteristics GO:0046546 23 0.325
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.308
positive regulation of protein autophosphorylation GO:0031954 9 0.303
double strand break repair via nonhomologous end joining GO:0006303 10 0.296
protein autophosphorylation GO:0046777 123 0.296
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.277
response to abiotic stimulus GO:0009628 336 0.271
regulation of response to dna damage stimulus GO:2001020 94 0.264
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.249
negative regulation of dna metabolic process GO:0051053 57 0.249
protein ubiquitination GO:0016567 314 0.247
chordate embryonic development GO:0043009 34 0.246
regulation of kinase activity GO:0043549 314 0.246
translesion synthesis GO:0019985 8 0.224
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.220
base excision repair GO:0006284 21 0.218
reciprocal dna recombination GO:0035825 4 0.216
organelle fission GO:0048285 149 0.215
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.214
isotype switching GO:0045190 3 0.208
positive regulation of cell death GO:0010942 263 0.204
response to light stimulus GO:0009416 87 0.202
mitotic cell cycle process GO:1903047 286 0.196
purine nucleotide catabolic process GO:0006195 405 0.183
peptidyl serine phosphorylation GO:0018105 101 0.180
histone modification GO:0016570 251 0.178
mitotic recombination GO:0006312 8 0.173
mitotic dna damage checkpoint GO:0044773 28 0.172
dna duplex unwinding GO:0032508 30 0.172
lipid localization GO:0010876 106 0.172
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.171
positive regulation of programmed cell death GO:0043068 249 0.168
cellular macromolecule catabolic process GO:0044265 380 0.167
somatic diversification of immunoglobulins GO:0016445 6 0.167
positive regulation of phosphorylation GO:0042327 394 0.166
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.161
regulation of protein catabolic process GO:0042176 155 0.161
regulation of dna replication GO:0006275 68 0.159
ion homeostasis GO:0050801 230 0.158
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.155
positive regulation of dna damage response signal transduction by p53 class mediator GO:0043517 8 0.155
reciprocal meiotic recombination GO:0007131 4 0.154
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.154
dna catabolic process GO:0006308 49 0.149
reproductive process GO:0022414 106 0.149
Mouse
meiotic nuclear division GO:0007126 10 0.145
Mouse
cell cycle arrest GO:0007050 71 0.142
dna biosynthetic process GO:0071897 40 0.138
regulation of proteasomal protein catabolic process GO:0061136 87 0.126
meiosis i GO:0007127 4 0.123
Mouse
dna catabolic process endonucleolytic GO:0000737 37 0.121
negative regulation of multicellular organismal process GO:0051241 317 0.120
gene silencing GO:0016458 49 0.120
regulation of cell cycle phase transition GO:1901987 126 0.119
neuromuscular process controlling balance GO:0050885 7 0.117
regulation of proteolysis GO:0030162 293 0.116
regulation of protein ubiquitination GO:0031396 95 0.116
response to caffeine GO:0031000 3 0.116
chromosome segregation GO:0007059 114 0.114
mitotic cell cycle phase transition GO:0044772 162 0.113
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.112
regulation of double strand break repair via homologous recombination GO:0010569 11 0.111
cellular lipid metabolic process GO:0044255 303 0.111
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.110
response to nitrogen compound GO:1901698 184 0.110
male gonad development GO:0008584 23 0.110
nuclear division GO:0000280 128 0.109
Mouse
dna conformation change GO:0071103 113 0.108
oogenesis GO:0048477 2 0.104
negative regulation of cell cycle process GO:0010948 121 0.104
calcium ion homeostasis GO:0055074 122 0.104
ribonucleoside catabolic process GO:0042454 406 0.104
regulation of double strand break repair GO:2000779 22 0.103
negative regulation of cell cycle GO:0045786 193 0.103
glycosyl compound catabolic process GO:1901658 413 0.102
ribonucleotide catabolic process GO:0009261 405 0.101
regulation of protein maturation GO:1903317 150 0.101
immune effector process GO:0002252 159 0.100
positive regulation of meiotic cell cycle GO:0051446 2 0.100
immune response GO:0006955 307 0.100
mitochondrion organization GO:0007005 156 0.099
regulation of dna dependent dna replication GO:0090329 19 0.098
histone h4 k20 methylation GO:0034770 1 0.097
regulation of leukocyte activation GO:0002694 115 0.093
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.093
positive regulation of hydrolase activity GO:0051345 331 0.091
negative regulation of mitotic cell cycle GO:0045930 102 0.090
lymphocyte activation GO:0046649 133 0.089
hemopoiesis GO:0030097 180 0.089
mitotic cell cycle checkpoint GO:0007093 68 0.087
female gamete generation GO:0007292 2 0.087
internal peptidyl lysine acetylation GO:0018393 97 0.087
dna dependent dna replication GO:0006261 44 0.085
negative regulation of cell proliferation GO:0008285 228 0.084
production of molecular mediator of immune response GO:0002440 37 0.081
apoptotic signaling pathway GO:0097190 268 0.081
spermatid development GO:0007286 4 0.080
intra s dna damage checkpoint GO:0031573 4 0.080
regulation of protein serine threonine kinase activity GO:0071900 179 0.079
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.078
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.077
negative regulation of cellular protein catabolic process GO:1903363 38 0.077
regulation of signal transduction by p53 class mediator GO:1901796 26 0.077
chemical homeostasis GO:0048878 306 0.076
positive regulation of telomere maintenance GO:0032206 4 0.074
post embryonic development GO:0009791 2 0.074
somitogenesis GO:0001756 2 0.073
neuromuscular process GO:0050905 15 0.073
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.073
non recombinational repair GO:0000726 14 0.072
negative regulation of cellular catabolic process GO:0031330 83 0.071
cell division GO:0051301 168 0.071
strand invasion GO:0042148 2 0.069
negative regulation of cell cycle phase transition GO:1901988 89 0.066
histone h4 acetylation GO:0043967 47 0.066
chromatin organization GO:0006325 351 0.065
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.065
immune system development GO:0002520 195 0.064
lipid biosynthetic process GO:0008610 177 0.063
proteasomal protein catabolic process GO:0010498 176 0.063
positive regulation of developmental process GO:0051094 314 0.062
positive regulation of protein phosphorylation GO:0001934 313 0.062
histone h2a phosphorylation GO:1990164 3 0.062
peptidyl lysine acetylation GO:0018394 101 0.062
negative regulation of protein phosphorylation GO:0001933 140 0.060
microtubule cytoskeleton organization GO:0000226 176 0.060
jnk cascade GO:0007254 80 0.059
mitotic dna integrity checkpoint GO:0044774 30 0.059
regulation of dna repair GO:0006282 47 0.059
regulation of protein transport GO:0051223 213 0.058
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.058
purine nucleoside monophosphate metabolic process GO:0009126 186 0.057
positive regulation of endopeptidase activity GO:0010950 84 0.057
positive regulation of apoptotic process GO:0043065 246 0.057
protein homooligomerization GO:0051260 100 0.057
negative regulation of developmental process GO:0051093 247 0.056
embryo development GO:0009790 123 0.056
rho protein signal transduction GO:0007266 26 0.056
cytokine production GO:0001816 247 0.056
negative regulation of protein processing GO:0010955 142 0.055
protein maturation GO:0051604 233 0.055
anterior posterior axis specification GO:0009948 2 0.055
male sex differentiation GO:0046661 25 0.054
organophosphate catabolic process GO:0046434 430 0.054
rna dependent dna replication GO:0006278 16 0.054
regulation of protein kinase activity GO:0045859 289 0.054
response to organonitrogen compound GO:0010243 156 0.051
adaptive immune response GO:0002250 49 0.050
protein deubiquitination GO:0016579 79 0.050
tissue homeostasis GO:0001894 63 0.048
ribonucleoside triphosphate metabolic process GO:0009199 412 0.048
interstrand cross link repair GO:0036297 3 0.047
segmentation GO:0035282 4 0.047
neuron death GO:0070997 65 0.047
negative regulation of neurological system process GO:0031645 2 0.046
negative regulation of sister chromatid segregation GO:0033046 17 0.046
cellular chemical homeostasis GO:0055082 180 0.045
protein polyubiquitination GO:0000209 110 0.045
purine nucleoside catabolic process GO:0006152 398 0.045
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.044
positive regulation of osteoblast differentiation GO:0045669 23 0.044
regulation of cellular protein catabolic process GO:1903362 96 0.044
negative regulation of programmed cell death GO:0043069 321 0.044
Zebrafish
nucleoside triphosphate catabolic process GO:0009143 394 0.044
positive regulation of proteolysis GO:0045862 142 0.043
signal transduction involved in dna damage checkpoint GO:0072422 15 0.043
growth GO:0040007 202 0.043
cell activation involved in immune response GO:0002263 30 0.042
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.042
regulation of peptidase activity GO:0052547 180 0.042
mitotic g2 dna damage checkpoint GO:0007095 7 0.042
neuron apoptotic process GO:0051402 39 0.041
cellular divalent inorganic cation homeostasis GO:0072503 128 0.041
response to transforming growth factor beta GO:0071559 94 0.040
positive regulation of mapk cascade GO:0043410 190 0.040
regulation of protein binding GO:0043393 66 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
negative regulation of dna replication GO:0008156 29 0.040
regulation of cell cycle GO:0051726 393 0.039
actin filament based process GO:0030029 224 0.039
response to oxygen containing compound GO:1901700 369 0.038
leukocyte mediated immunity GO:0002443 59 0.038
regulation of cell division GO:0051302 116 0.038
cellular response to ionizing radiation GO:0071479 32 0.038
negative regulation of defense response GO:0031348 47 0.037
positive regulation of signal transduction by p53 class mediator GO:1901798 10 0.036
phospholipid metabolic process GO:0006644 99 0.036
regulation of intracellular transport GO:0032386 195 0.036
positive regulation of cytokine production GO:0001819 167 0.036
regulation of endopeptidase activity GO:0052548 170 0.035
cellular protein catabolic process GO:0044257 261 0.035
female gonad development GO:0008585 10 0.035
ubiquitin dependent protein catabolic process GO:0006511 206 0.035
cellular response to abiotic stimulus GO:0071214 117 0.035
single organism cellular localization GO:1902580 332 0.035
regulation of inflammatory response GO:0050727 46 0.035
regulation of mitotic cell cycle phase transition GO:1901990 118 0.035
negative regulation of protein maturation GO:1903318 142 0.035
peptidyl serine modification GO:0018209 106 0.034
negative regulation of immune system process GO:0002683 136 0.034
regulation of neuron apoptotic process GO:0043523 35 0.033
intracellular protein transport GO:0006886 270 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
lipid metabolic process GO:0006629 381 0.033
mapk cascade GO:0000165 288 0.033
response to transition metal nanoparticle GO:1990267 29 0.032
cellular metal ion homeostasis GO:0006875 146 0.032
glycerolipid biosynthetic process GO:0045017 51 0.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.032
gene conversion GO:0035822 1 0.032
single organism carbohydrate metabolic process GO:0044723 193 0.032
positive regulation of cellular component biogenesis GO:0044089 158 0.032
nucleotide catabolic process GO:0009166 408 0.032
negative regulation of response to wounding GO:1903035 47 0.031
positive regulation of protein ubiquitination GO:0031398 53 0.031
regulation of dna endoreduplication GO:0032875 5 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
carbohydrate metabolic process GO:0005975 207 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
cellular response to organonitrogen compound GO:0071417 124 0.030
cell activation GO:0001775 213 0.030
regulation of cytoplasmic transport GO:1903649 149 0.030
interleukin 6 production GO:0032635 37 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
macromolecule methylation GO:0043414 97 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
regulation of response to wounding GO:1903034 101 0.030
determination of adult lifespan GO:0008340 2 0.030
protein stabilization GO:0050821 64 0.029
regulation of multi organism process GO:0043900 157 0.029
cation homeostasis GO:0055080 189 0.029
metal ion homeostasis GO:0055065 169 0.029
leukocyte differentiation GO:0002521 98 0.029
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
positive regulation of developmental growth GO:0048639 16 0.029
regulation of viral process GO:0050792 103 0.028
regulation of protein targeting GO:1903533 91 0.028
cellular response to light stimulus GO:0071482 34 0.028
ribonucleoside monophosphate catabolic process GO:0009158 158 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
cellular cation homeostasis GO:0030003 163 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.027
positive regulation of transport GO:0051050 336 0.027
ovulation cycle process GO:0022602 9 0.027
mitotic spindle checkpoint GO:0071174 18 0.027
regulation of growth GO:0040008 165 0.027
positive regulation of binding GO:0051099 45 0.027
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.026
spermatid differentiation GO:0048515 4 0.026
regulation of telomerase activity GO:0051972 9 0.026
system process GO:0003008 349 0.026
detection of stimulus GO:0051606 85 0.026
negative regulation of dna dependent dna replication GO:2000104 9 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
negative regulation of protein metabolic process GO:0051248 391 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
nervous system development GO:0007399 293 0.025
regulation of mapk cascade GO:0043408 262 0.025
mitotic g1 dna damage checkpoint GO:0031571 17 0.024
leukocyte activation involved in immune response GO:0002366 30 0.024
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.024
regulation of cell cycle process GO:0010564 266 0.024
negative regulation of cell death GO:0060548 345 0.023
Zebrafish
cell aging GO:0007569 52 0.023
leukocyte activation GO:0045321 164 0.023
somatic diversification of immune receptors GO:0002200 8 0.023
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.023
chromatin silencing GO:0006342 12 0.023
regulation of developmental growth GO:0048638 30 0.022
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.022
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.022
protein processing GO:0016485 226 0.022
response to organic cyclic compound GO:0014070 204 0.022
cell cycle phase transition GO:0044770 173 0.022
multicellular organismal signaling GO:0035637 34 0.022
spindle assembly checkpoint GO:0071173 17 0.022
mononuclear cell proliferation GO:0032943 71 0.022
protein dephosphorylation GO:0006470 81 0.022
positive regulation of secretion by cell GO:1903532 108 0.021
single organism reproductive process GO:0044702 98 0.021
Mouse
cdc42 protein signal transduction GO:0032488 4 0.021
mitotic g2 m transition checkpoint GO:0044818 9 0.021
cell type specific apoptotic process GO:0097285 125 0.021
regulation of protein stability GO:0031647 87 0.021
regulation of mononuclear cell proliferation GO:0032944 65 0.021
central nervous system development GO:0007417 123 0.021
actin filament based movement GO:0030048 17 0.021
mitotic cell cycle GO:0000278 326 0.021
negative regulation of mitosis GO:0045839 24 0.021
response to ionizing radiation GO:0010212 65 0.021
positive regulation of chromosome organization GO:2001252 41 0.021
response to lipid GO:0033993 206 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
regulation of defense response GO:0031347 154 0.020
transmission of nerve impulse GO:0019226 11 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
negative regulation of lipid metabolic process GO:0045833 38 0.020
protein acetylation GO:0006473 116 0.020
brain development GO:0007420 97 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
defense response GO:0006952 315 0.020
carboxylic acid biosynthetic process GO:0046394 97 0.020
organelle assembly GO:0070925 176 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
protein monoubiquitination GO:0006513 39 0.020
metencephalon development GO:0022037 2 0.020
multicellular organismal reproductive process GO:0048609 40 0.019
Mouse
single organism membrane organization GO:0044802 268 0.019
regulation of protein processing GO:0070613 150 0.019
action potential GO:0001508 34 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
myosin filament assembly GO:0031034 2 0.019
negative regulation of transferase activity GO:0051348 124 0.019
cellular calcium ion homeostasis GO:0006874 117 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
immunoglobulin production GO:0002377 12 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
gtp catabolic process GO:0006184 237 0.019
negative regulation of response to dna damage stimulus GO:2001021 33 0.019
b cell differentiation GO:0030183 6 0.019
positive regulation of protein transport GO:0051222 135 0.018
vesicle mediated transport GO:0016192 371 0.018
positive regulation of cell cycle GO:0045787 140 0.018
actin cytoskeleton organization GO:0030036 207 0.018
male gamete generation GO:0048232 22 0.018
regulation of lymphocyte proliferation GO:0050670 64 0.018
regulation of immune response GO:0050776 201 0.018
response to drug GO:0042493 81 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
response to molecule of bacterial origin GO:0002237 82 0.018
lymphocyte proliferation GO:0046651 70 0.018
cellular response to external stimulus GO:0071496 111 0.018
reproduction GO:0000003 63 0.018
Mouse
regulation of establishment of protein localization GO:0070201 242 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
response to external biotic stimulus GO:0043207 261 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
phospholipid biosynthetic process GO:0008654 44 0.018
negative regulation of b cell proliferation GO:0030889 5 0.017
detection of chemical stimulus GO:0009593 55 0.017
negative regulation of histone h3 k9 methylation GO:0051573 3 0.017
b cell activation GO:0042113 33 0.017
regulation of jnk cascade GO:0046328 73 0.017
morphogenesis of an epithelium GO:0002009 60 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
hair follicle morphogenesis GO:0031069 2 0.017
nucleoside catabolic process GO:0009164 408 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.017
positive regulation of response to dna damage stimulus GO:2001022 43 0.017
lymphocyte mediated immunity GO:0002449 48 0.017
replicative senescence GO:0090399 8 0.017
negative regulation of cell division GO:0051782 31 0.017
response to unfolded protein GO:0006986 24 0.017
maintenance of location GO:0051235 112 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
lipid storage GO:0019915 28 0.016
amine metabolic process GO:0009308 44 0.016
negative regulation of protein catabolic process GO:0042177 59 0.016
neurological system process GO:0050877 163 0.016
cellular ion homeostasis GO:0006873 168 0.016
leukocyte proliferation GO:0070661 74 0.016
neuronal action potential GO:0019228 9 0.016
positive regulation of neuron apoptotic process GO:0043525 8 0.016
hindbrain development GO:0030902 3 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
response to hormone GO:0009725 175 0.015
positive regulation of protein localization to nucleus GO:1900182 48 0.015
neural tube formation GO:0001841 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
regulation of protein secretion GO:0050708 86 0.015
peptide transport GO:0015833 74 0.015
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 9 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
regulation of response to external stimulus GO:0032101 222 0.015
negative regulation of telomerase activity GO:0051974 6 0.015
protein catabolic process GO:0030163 325 0.015
cytokine mediated signaling pathway GO:0019221 109 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
cellular amino acid metabolic process GO:0006520 116 0.014
neuron development GO:0048666 113 0.014
protein modification by small protein removal GO:0070646 92 0.014
negative regulation of catabolic process GO:0009895 104 0.014
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.014
response to alkaloid GO:0043279 20 0.014
osteoblast development GO:0002076 2 0.014
phosphatidylinositol metabolic process GO:0046488 53 0.014
negative regulation of chromosome organization GO:2001251 48 0.014
histone ubiquitination GO:0016574 31 0.014
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.014
multicellular organism reproduction GO:0032504 42 0.014
Mouse
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.014
spindle checkpoint GO:0031577 26 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
positive regulation of catabolic process GO:0009896 310 0.014
purine containing compound catabolic process GO:0072523 411 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
myosin filament organization GO:0031033 2 0.014
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.014
positive regulation of homeostatic process GO:0032846 47 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
primary neural tube formation GO:0014020 3 0.014
regulation of protein localization GO:0032880 296 0.013
negative regulation of protein modification process GO:0031400 200 0.013
sequestering of calcium ion GO:0051208 17 0.013
response to hypoxia GO:0001666 96 0.013
steroid metabolic process GO:0008202 94 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
positive regulation of angiogenesis GO:0045766 51 0.013
regulation of membrane potential GO:0042391 95 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
compound eye development GO:0048749 1 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.013
intracellular mrna localization GO:0008298 1 0.013

FANCD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 1.000
hematopoietic system disease DOID:74 100 1.000
aplastic anemia DOID:12449 30 1.000
bone marrow disease DOID:4961 31 1.000
anemia DOID:2355 55 1.000
congenital hypoplastic anemia DOID:1342 26 0.993
fanconi s anemia DOID:13636 16 0.993
cancer DOID:162 167 0.983
disease of cellular proliferation DOID:14566 174 0.983
organ system cancer DOID:0050686 164 0.648
thoracic cancer DOID:5093 21 0.647
endocrine gland cancer DOID:170 26 0.632
pancreatic cancer DOID:1793 8 0.632
breast cancer DOID:1612 21 0.357
reproductive organ cancer DOID:193 23 0.163
hematologic cancer DOID:2531 36 0.027
immune system cancer DOID:0060083 36 0.027
central nervous system disease DOID:331 186 0.021
nervous system disease DOID:863 431 0.021
male reproductive organ cancer DOID:3856 16 0.019
prostate cancer DOID:10283 13 0.019
xeroderma pigmentosum DOID:0050427 8 0.018