|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
1.000
|
Human |
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
1.000
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
1.000
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.998
|
Mouse |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.998
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.998
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.998
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.997
|
Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.996
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.996
|
Rat |
|
|
protein processing
|
GO:0016485 |
226 |
0.995
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.994
|
|
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
0.993
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.993
|
Mouse |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.988
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.988
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.987
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.987
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.986
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.985
|
Rat |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.985
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.983
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.982
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.981
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.981
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.980
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.980
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.979
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.978
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.978
|
Rat |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.975
|
Rat |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.974
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.973
|
Rat |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.971
|
Human |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.971
|
Rat |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.970
|
Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.968
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.963
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.956
|
Rat |
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.955
|
Rat |
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.954
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.952
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.949
|
Human Mouse Rat |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.947
|
Mouse |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.942
|
Rat |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.941
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.941
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.937
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.937
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.929
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.929
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.925
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.921
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.916
|
Rat |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.913
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.906
|
Mouse |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.903
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.903
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.902
|
Rat |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.900
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.899
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.898
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.898
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.898
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
0.892
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.891
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.888
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.887
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.882
|
Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.881
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.878
|
Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.873
|
Mouse |
|
|
necroptotic process
|
GO:0070266 |
16 |
0.871
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.852
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.851
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.848
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.837
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.834
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.832
|
Mouse |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.828
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.824
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.821
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.821
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.819
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.817
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.809
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.809
|
Human |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.805
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.799
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.797
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.794
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.767
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.765
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.764
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.760
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.759
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.759
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.758
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.754
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.751
|
Rat |
|
|
regeneration
|
GO:0031099 |
4 |
0.747
|
Rat |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.746
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.741
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.735
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.733
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.712
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.708
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.702
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.686
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.682
|
Mouse Rat |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.673
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.671
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.670
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.667
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.666
|
Mouse |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.666
|
Mouse |
|
|
cell activation
|
GO:0001775 |
213 |
0.657
|
Mouse |
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.655
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.652
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.650
|
Rat |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.650
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.642
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.642
|
Mouse |
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.634
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.633
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.630
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.629
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.629
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.625
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.625
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.621
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.619
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.617
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.615
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.614
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.614
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.606
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.603
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.602
|
Mouse |
|
|
regulation of cellular extravasation
|
GO:0002691 |
8 |
0.597
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.590
|
Rat |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.587
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.585
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.585
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.584
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.581
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.578
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.574
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.573
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.572
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.563
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.561
|
Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.559
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.557
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.552
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.546
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.541
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.529
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.528
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.528
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.527
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.525
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.520
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.517
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.515
|
Mouse |
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.509
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.506
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.499
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.498
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.495
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.493
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.491
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.487
|
Rat |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.487
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.486
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.481
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.481
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.479
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.475
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.472
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.471
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.468
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.462
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.461
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.461
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.460
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.457
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.454
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.454
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.452
|
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
10 |
0.450
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.447
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.440
|
Rat |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.431
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.420
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.406
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.405
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.405
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.403
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.401
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.400
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.399
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.399
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.395
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.394
|
Human |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.394
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.391
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.389
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.388
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.387
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.379
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.377
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.376
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.374
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.369
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.368
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.365
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.363
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.362
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.361
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.352
|
Rat |
|
|
necroptotic signaling pathway
|
GO:0097527 |
6 |
0.351
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.348
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
7 |
0.345
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.344
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.344
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.339
|
|
|
|
positive regulation of endothelial cell apoptotic process
|
GO:2000353 |
8 |
0.338
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.337
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.336
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.335
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.332
|
Mouse |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.331
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.325
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.325
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.322
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.318
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.318
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.313
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.312
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.312
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.307
|
Rat |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.306
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.300
|
Rat |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.295
|
Mouse Rat |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.293
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.291
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.291
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.290
|
|
|
|
positive regulation of bone resorption
|
GO:0045780 |
2 |
0.290
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.287
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.287
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.286
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.285
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.285
|
Rat |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.284
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.280
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.279
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.278
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.278
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.277
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.277
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.276
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.275
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.275
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.275
|
Mouse |
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.272
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.272
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.271
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.271
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.265
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.265
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
8 |
0.262
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.260
|
Mouse |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.256
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.255
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.254
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.253
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.249
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.248
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.248
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.247
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.247
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.246
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.243
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.243
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.238
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.235
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.230
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.229
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.229
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.226
|
Rat |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.225
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.225
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.224
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.224
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.223
|
Rat |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.223
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.221
|
Mouse |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.220
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.218
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.217
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.217
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.214
|
Rat |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.209
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.206
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.205
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.204
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.202
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.201
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.201
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.200
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.199
|
Rat |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.197
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.196
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.195
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.195
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.193
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.192
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.190
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.190
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
2 |
0.190
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.189
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.188
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.188
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.187
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.187
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.184
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.184
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.183
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.183
|
Rat |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.183
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.182
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.181
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.179
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.179
|
Rat |
|
|
regulation of bone remodeling
|
GO:0046850 |
6 |
0.179
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.176
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.175
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.175
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.174
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.174
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.173
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.172
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.172
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.171
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.169
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.168
|
Rat |
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.167
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.166
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.165
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.165
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.165
|
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
12 |
0.164
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.163
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.162
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.161
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.156
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.155
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.152
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.152
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.152
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.152
|
Rat |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.150
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.149
|
Mouse Rat |
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.149
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.149
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.149
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.149
|
Mouse Rat |
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.147
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.146
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.146
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.146
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.146
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.145
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.143
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.143
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.142
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
9 |
0.139
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.138
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.136
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.135
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.135
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.135
|
Mouse |
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.135
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.133
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.133
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.131
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.129
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.127
|
Mouse |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.126
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.125
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.124
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.124
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.124
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.123
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.122
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.121
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.121
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.120
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.119
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.118
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.118
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.118
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.117
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.117
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.117
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.116
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.115
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.115
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.115
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.110
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.110
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.110
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.110
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.108
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.107
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.107
|
|
|
|
growth
|
GO:0040007 |
202 |
0.106
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
8 |
0.104
|
Human |
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.104
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.103
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.103
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.102
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.101
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.101
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.101
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.101
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.101
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.100
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.100
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.100
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.099
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.099
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.099
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.098
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.096
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.094
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.094
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.093
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.093
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.093
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
8 |
0.092
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.092
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.092
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.092
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.092
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.091
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.090
|
Mouse |
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.090
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.090
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.090
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.090
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.090
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.089
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.089
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.088
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.088
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.087
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.087
|
Rat |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.085
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.085
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.084
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.084
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.084
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.084
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.083
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.083
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.083
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.083
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.083
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.082
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.081
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.080
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.080
|
|
|
|
head development
|
GO:0060322 |
108 |
0.079
|
Rat |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.078
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.078
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.077
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.077
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.077
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.077
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.077
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.076
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.075
|
|
|
|
regulation of intracellular transport of viral material
|
GO:1901252 |
2 |
0.075
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.075
|
Human |
