Homo sapiens

11 known processes

FBLN5

fibulin 5

(Aliases: FLJ90059,FIBL-5,DANCE,ARMD3,EVEC,UP50)

FBLN5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mesenchymal stem cell proliferation GO:1902460 1 0.988
Human
mesenchymal stem cell proliferation GO:0097168 1 0.965
Human
positive regulation of mesenchymal stem cell proliferation GO:1902462 1 0.759
Human
transforming growth factor beta activation GO:0036363 1 0.597
Human
transforming growth factor beta production GO:0071604 14 0.591
Human
peptidyl tyrosine modification GO:0018212 170 0.366
Human
stem cell differentiation GO:0048863 93 0.319
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.290
Human
regulation of chondrocyte differentiation GO:0032330 9 0.202
Human
sprouting angiogenesis GO:0002040 29 0.190
positive regulation of stem cell proliferation GO:2000648 10 0.181
Human
extracellular structure organization GO:0043062 41 0.169
Mouse
negative regulation of cartilage development GO:0061037 5 0.167
Human
regulation of stem cell proliferation GO:0072091 15 0.165
Human
mesenchymal stem cell differentiation GO:0072497 8 0.163
Human
cellular component morphogenesis GO:0032989 314 0.157
regulation of cartilage development GO:0061035 12 0.152
Human
negative regulation of cell differentiation GO:0045596 171 0.147
Human
response to oxygen containing compound GO:1901700 369 0.138
Mouse
cytokine production GO:0001816 247 0.126
Human
ameboidal type cell migration GO:0001667 135 0.124
chromatin modification GO:0016568 298 0.124
response to lipid GO:0033993 206 0.107
positive regulation of developmental process GO:0051094 314 0.107
Human
regulation of cell differentiation GO:0045595 393 0.100
Human
response to other organism GO:0051707 261 0.097
covalent chromatin modification GO:0016569 254 0.077
oxidation reduction process GO:0055114 396 0.077
positive regulation of mesenchymal stem cell differentiation GO:2000741 4 0.074
Human
response to inorganic substance GO:0010035 127 0.063
Mouse
response to molecule of bacterial origin GO:0002237 82 0.062
response to external biotic stimulus GO:0043207 261 0.060
positive regulation of locomotion GO:0040017 186 0.059
chromatin organization GO:0006325 351 0.058
skeletal system development GO:0001501 79 0.058
Human
histone modification GO:0016570 251 0.057
response to transition metal nanoparticle GO:1990267 29 0.056
anatomical structure formation involved in morphogenesis GO:0048646 284 0.055
response to biotic stimulus GO:0009607 276 0.053
response to metal ion GO:0010038 84 0.052
elastic fiber assembly GO:0048251 3 0.048
Mouse
regulation of mesenchymal stem cell differentiation GO:2000739 6 0.046
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.046
Human
regulation of locomotion GO:0040012 329 0.045
enzyme linked receptor protein signaling pathway GO:0007167 303 0.045
Human
regulation of proteolysis GO:0030162 293 0.042
Human
sequestering of extracellular ligand from receptor GO:0035581 3 0.042
circulatory system development GO:0072359 262 0.042
chondrocyte differentiation GO:0002062 17 0.041
Human
post embryonic development GO:0009791 2 0.040
positive regulation of stem cell differentiation GO:2000738 29 0.040
Human
epithelial cell proliferation GO:0050673 128 0.038
epithelial cell migration GO:0010631 119 0.038
vasculature development GO:0001944 181 0.037
cartilage development GO:0051216 31 0.036
Human
response to copper ion GO:0046688 8 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
positive regulation of cell proliferation GO:0008284 301 0.035
Human
cellular amine metabolic process GO:0044106 41 0.034
response to bacterium GO:0009617 144 0.034
positive regulation of immune system process GO:0002684 283 0.032
cell development GO:0048468 328 0.032
cellular macromolecular complex assembly GO:0034622 324 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
Human
cellular response to growth factor stimulus GO:0071363 197 0.031
stem cell proliferation GO:0072089 25 0.030
Human
response to hormone GO:0009725 175 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
multicellular organismal aging GO:0010259 3 0.029
cellular response to endogenous stimulus GO:0071495 336 0.028
response to wounding GO:0009611 168 0.028
cell morphogenesis GO:0000902 296 0.027
cell morphogenesis involved in differentiation GO:0000904 144 0.027
determination of adult lifespan GO:0008340 2 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
actin filament based process GO:0030029 224 0.026
organophosphate catabolic process GO:0046434 430 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
endothelial cell proliferation GO:0001935 65 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
regulation of cytoskeleton organization GO:0051493 177 0.026
protein catabolic process GO:0030163 325 0.025
tissue migration GO:0090130 119 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
regulation of peptidase activity GO:0052547 180 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
immune response GO:0006955 307 0.024
positive regulation of immune response GO:0050778 159 0.024
blood vessel morphogenesis GO:0048514 162 0.023
cellular amino acid metabolic process GO:0006520 116 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
response to lipopolysaccharide GO:0032496 70 0.022
aorta development GO:0035904 2 0.022
purine containing compound catabolic process GO:0072523 411 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
innate immune response GO:0045087 178 0.022
regulation of cell cycle GO:0051726 393 0.022
protein processing GO:0016485 226 0.021
system process GO:0003008 349 0.021
cardiovascular system development GO:0072358 262 0.021
negative regulation of protein modification process GO:0031400 200 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
nervous system development GO:0007399 293 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
extracellular matrix organization GO:0030198 41 0.020
Mouse
positive regulation of catabolic process GO:0009896 310 0.020
neurogenesis GO:0022008 169 0.020
regeneration GO:0031099 4 0.020
retinal ganglion cell axon guidance GO:0031290 2 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
regulation of axon extension involved in axon guidance GO:0048841 2 0.019
transmembrane transport GO:0055085 399 0.019
positive regulation of axon extension GO:0045773 4 0.019
female gamete generation GO:0007292 2 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
epidermal growth factor receptor signaling pathway GO:0007173 39 0.019
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
cytoplasmic transport GO:0016482 379 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
amine metabolic process GO:0009308 44 0.018
protein maturation GO:0051604 233 0.018
cellular protein catabolic process GO:0044257 261 0.018
compound eye development GO:0048749 1 0.018
nucleotide catabolic process GO:0009166 408 0.018
cellular protein complex assembly GO:0043623 188 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
chemical homeostasis GO:0048878 306 0.018
defense response GO:0006952 315 0.018
peripheral nervous system development GO:0007422 2 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
response to cytokine GO:0034097 232 0.018
regulation of chemotaxis GO:0050920 74 0.018
positive regulation of synaptic transmission GO:0050806 4 0.018
positive regulation of cell adhesion GO:0045785 84 0.018
nucleoside catabolic process GO:0009164 408 0.018
neuromuscular junction development GO:0007528 3 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
response to organic cyclic compound GO:0014070 204 0.017
cellular ketone metabolic process GO:0042180 80 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
regulation of bmp signaling pathway GO:0030510 27 0.017
regulation of actin filament based process GO:0032970 141 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
regulation of cytokine production GO:0001817 232 0.017
negative regulation of locomotion GO:0040013 118 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
mitotic cell cycle process GO:1903047 286 0.016
segmentation GO:0035282 4 0.016
epithelial to mesenchymal transition GO:0001837 48 0.016
regulation of cellular response to growth factor stimulus GO:0090287 76 0.016
developmental programmed cell death GO:0010623 3 0.016
mitotic cell cycle GO:0000278 326 0.016
rho protein signal transduction GO:0007266 26 0.016
dephosphorylation GO:0016311 209 0.016
epithelium migration GO:0090132 119 0.016
regulation of kinase activity GO:0043549 314 0.016
regulation of axon guidance GO:1902667 3 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
Mouse
regulation of protein processing GO:0070613 150 0.016
regulation of cell cycle process GO:0010564 266 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
regulation of protein complex assembly GO:0043254 147 0.015
immune effector process GO:0002252 159 0.015
proteoglycan metabolic process GO:0006029 29 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
Human
reactive nitrogen species metabolic process GO:2001057 3 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
secretion by cell GO:0032940 226 0.015
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.015
corticospinal tract morphogenesis GO:0021957 1 0.015
mesenchyme development GO:0060485 59 0.015
stress fiber assembly GO:0043149 40 0.015
apoptotic signaling pathway GO:0097190 268 0.015
negative regulation of neutrophil chemotaxis GO:0090024 2 0.015
bmp signaling pathway GO:0030509 49 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
microtubule based process GO:0007017 210 0.015
neuroblast proliferation GO:0007405 4 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
maintenance of location GO:0051235 112 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
response to axon injury GO:0048678 1 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
locomotory behavior GO:0007626 1 0.014
cell activation GO:0001775 213 0.014
oogenesis GO:0048477 2 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
regulation of cellular response to stress GO:0080135 244 0.014
Mouse
collagen fibril organization GO:0030199 10 0.014
regulation of immune response GO:0050776 201 0.014
cellular lipid metabolic process GO:0044255 303 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of cell motility GO:2000145 299 0.014
activation of immune response GO:0002253 114 0.014
positive regulation of proteolysis GO:0045862 142 0.014
negative regulation of cell growth GO:0030308 83 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
spermatid development GO:0007286 4 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
cation transport GO:0006812 331 0.014
mitochondrion organization GO:0007005 156 0.014
gas transport GO:0015669 3 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
regulation of protein catabolic process GO:0042176 155 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
forebrain generation of neurons GO:0021872 3 0.014
rhythmic behavior GO:0007622 2 0.014
lipid metabolic process GO:0006629 381 0.014
negative regulation of chondrocyte differentiation GO:0032331 5 0.014
Human
signal transduction by phosphorylation GO:0023014 297 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
carbohydrate metabolic process GO:0005975 207 0.013
single organism cell adhesion GO:0098602 179 0.013
regulation of response to external stimulus GO:0032101 222 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
cell type specific apoptotic process GO:0097285 125 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
gtp catabolic process GO:0006184 237 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
negative regulation of organelle organization GO:0010639 126 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
protein ubiquitination GO:0016567 314 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
negative regulation of bmp signaling pathway GO:0030514 17 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
protein targeting GO:0006605 187 0.013
cell matrix adhesion GO:0007160 85 0.013
cation transmembrane transport GO:0098655 238 0.012
regulation of cell activation GO:0050865 125 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
nitrogen compound transport GO:0071705 191 0.012
cell projection morphogenesis GO:0048858 129 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of actin filament polymerization GO:0030833 50 0.012
circadian behavior GO:0048512 2 0.012
multicellular organismal metabolic process GO:0044236 34 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
generation of neurons GO:0048699 152 0.012
positive regulation of chemotaxis GO:0050921 57 0.012
regulation of membrane potential GO:0042391 95 0.012
blastoderm segmentation GO:0007350 2 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
intracellular protein transport GO:0006886 270 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
anion transport GO:0006820 161 0.012
t cell differentiation in thymus GO:0033077 4 0.012
limbic system development GO:0021761 3 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
negative regulation of protein processing GO:0010955 142 0.012
ossification GO:0001503 121 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
hemostasis GO:0007599 76 0.012
regulation of cell projection organization GO:0031344 107 0.012
actin mediated cell contraction GO:0070252 12 0.012
response to oxygen levels GO:0070482 100 0.011
anterior posterior axis specification GO:0009948 2 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
neurological system process GO:0050877 163 0.011
establishment of planar polarity GO:0001736 3 0.011
blood vessel development GO:0001568 172 0.011
positive regulation of cytokine production GO:0001819 167 0.011
gtp metabolic process GO:0046039 239 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
positive regulation of transport GO:0051050 336 0.011
response to salt stress GO:0009651 3 0.011
regulation of protein transport GO:0051223 213 0.011
mapk cascade GO:0000165 288 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
positive regulation of secretion GO:0051047 116 0.011
negative regulation of axon guidance GO:1902668 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
response to drug GO:0042493 81 0.011
regulation of innate immune response GO:0045088 97 0.011
chondroitin sulfate metabolic process GO:0030204 7 0.011
negative regulation of proteolysis GO:0045861 132 0.011
metal ion transport GO:0030001 272 0.011
atp metabolic process GO:0046034 176 0.011
forebrain neuron differentiation GO:0021879 3 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
small molecule biosynthetic process GO:0044283 157 0.011
peptidyl serine modification GO:0018209 106 0.011
tripartite regional subdivision GO:0007351 2 0.011
endothelial cell migration GO:0043542 86 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
chondroitin sulfate proteoglycan metabolic process GO:0050654 10 0.011
rna interference GO:0016246 4 0.011
renal water homeostasis GO:0003091 4 0.011
positive regulation of transferase activity GO:0051347 227 0.011
visual behavior GO:0007632 2 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
negative regulation of transport GO:0051051 176 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
detection of stimulus GO:0051606 85 0.010
cellular response to hormone stimulus GO:0032870 125 0.010
ion transmembrane transport GO:0034220 338 0.010
epithelial cell differentiation GO:0030855 141 0.010
vesicle mediated transport GO:0016192 371 0.010
sensory perception GO:0007600 103 0.010
stress activated mapk cascade GO:0051403 93 0.010
immune response activating signal transduction GO:0002757 90 0.010
regulation of secretion by cell GO:1903530 177 0.010
lipid biosynthetic process GO:0008610 177 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
platelet activation GO:0030168 44 0.010
protein secretion GO:0009306 98 0.010
protein oligomerization GO:0051259 173 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.010

FBLN5 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.992
eye and adnexa disease DOID:1492 150 0.992
nervous system disease DOID:863 431 0.992
eye disease DOID:5614 149 0.992
retinal disease DOID:5679 118 0.984
glaucoma DOID:1686 8 0.290
Human
retinal degeneration DOID:8466 89 0.290
uveal disease DOID:3480 4 0.038
myopathy DOID:423 104 0.030
muscular disease DOID:0080000 114 0.030
musculoskeletal system disease DOID:17 223 0.030
muscle tissue disease DOID:66 113 0.030
cardiovascular system disease DOID:1287 106 0.021
heart disease DOID:114 68 0.018
muscular dystrophy DOID:9884 51 0.016
central nervous system disease DOID:331 186 0.015
disease of metabolism DOID:0014667 295 0.014
immune system disease DOID:2914 155 0.013
neurodegenerative disease DOID:1289 102 0.012
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.011
degeneration of macula and posterior pole DOID:2007 17 0.005
macular degeneration DOID:4448 20 0.005
age related macular degeneration DOID:10871 17 0.005