Homo sapiens

14 known processes

FLNB

filamin B, beta

(Aliases: ABP-280,TAP,LRS1,ABP-278,TABP,DKFZp686A1668,AOI,DKFZp686O033,SCT,FH1,FLN1L)

FLNB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.988
actin filament based process GO:0030029 224 0.960
Human Mouse Worm Fly
membrane organization GO:0061024 292 0.875
Human
somitogenesis GO:0001756 2 0.860
motor neuron axon guidance GO:0008045 2 0.847
Fly
amine metabolic process GO:0009308 44 0.832
cellular amine metabolic process GO:0044106 41 0.829
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.789
actin cytoskeleton organization GO:0030036 207 0.783
Human Mouse Worm Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.777
Human Fly
calcium ion transmembrane transport GO:0070588 76 0.767
mapk cascade GO:0000165 288 0.763
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.753
Human
brain morphogenesis GO:0048854 1 0.732
regulation of protein kinase activity GO:0045859 289 0.727
single organismal cell cell adhesion GO:0016337 148 0.713
Human
regulation of locomotion GO:0040012 329 0.710
protein localization to membrane GO:0072657 160 0.709
Human
cation transmembrane transport GO:0098655 238 0.702
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.695
positive regulation of map kinase activity GO:0043406 80 0.691
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.670
positive regulation of mapk cascade GO:0043410 190 0.668
cellular response to growth factor stimulus GO:0071363 197 0.648
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.635
single organism nuclear import GO:1902593 104 0.633
Human
post embryonic organ development GO:0048569 1 0.633
Fly
positive regulation of protein kinase activity GO:0045860 190 0.633
regulation of cellular amino acid metabolic process GO:0006521 6 0.632
enzyme linked receptor protein signaling pathway GO:0007167 303 0.626
regulation of actin cytoskeleton organization GO:0032956 116 0.625
thymus development GO:0048538 3 0.603
multicellular organismal aging GO:0010259 3 0.593
Fly
response to growth factor GO:0070848 205 0.589
regulation of collagen catabolic process GO:0010710 3 0.587
dopamine receptor signaling pathway GO:0007212 10 0.582
Human
positive regulation of protein phosphorylation GO:0001934 313 0.571
regulation of cell migration GO:0030334 289 0.570
pericardium development GO:0060039 2 0.569
peptidyl tyrosine phosphorylation GO:0018108 170 0.562
actin filament organization GO:0007015 128 0.562
Human Worm Fly
peptidyl tyrosine modification GO:0018212 170 0.561
regulation of cytoskeleton organization GO:0051493 177 0.560
Fly
epithelial cell differentiation GO:0030855 141 0.558
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.557
epithelium development GO:0060429 227 0.552
Mouse Fly
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.542
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.534
integrin mediated signaling pathway GO:0007229 32 0.533
cell adhesion GO:0007155 325 0.531
Human
response to transforming growth factor beta GO:0071559 94 0.520
ameboidal type cell migration GO:0001667 135 0.520
striated muscle contraction GO:0006941 52 0.518
regulation of mapk cascade GO:0043408 262 0.511
determination of adult lifespan GO:0008340 2 0.509
Fly
inorganic cation transmembrane transport GO:0098662 194 0.503
cellular component morphogenesis GO:0032989 314 0.501
Human Mouse Fly
locomotory behavior GO:0007626 1 0.500
biological adhesion GO:0022610 331 0.500
Human
protein catabolic process GO:0030163 325 0.494
Human
hair cycle phase GO:0044851 3 0.492
memory GO:0007613 3 0.491
cerebral cortex cell migration GO:0021795 3 0.490
cardiac muscle tissue development GO:0048738 39 0.490
cellular ketone metabolic process GO:0042180 80 0.490
regulation of cellular amine metabolic process GO:0033238 11 0.489
positive regulation of phosphorylation GO:0042327 394 0.487
regulation of protein import into nucleus GO:0042306 78 0.486
Human
segmentation GO:0035282 4 0.483
muscle contraction GO:0006936 73 0.481
negative regulation of cell death GO:0060548 345 0.465
single organism cellular localization GO:1902580 332 0.464
Human
tube development GO:0035295 125 0.455
neural tube patterning GO:0021532 2 0.455
protein import GO:0017038 130 0.438
Human
cellular amino acid metabolic process GO:0006520 116 0.437
neurological system process GO:0050877 163 0.436
Fly
positive regulation of transcription factor import into nucleus GO:0042993 25 0.434
Human
regulation of transcription factor import into nucleus GO:0042990 39 0.431
Human
actin crosslink formation GO:0051764 1 0.431
Human
positive regulation of protein import into nucleus GO:0042307 46 0.430
Human
cellular macromolecular complex assembly GO:0034622 324 0.414
early endosome to late endosome transport GO:0045022 21 0.412
positive regulation of intracellular transport GO:0032388 104 0.411
Human
transmembrane transport GO:0055085 399 0.411
actomyosin structure organization GO:0031032 59 0.408
metal ion transport GO:0030001 272 0.392
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.391
Human
positive regulation of locomotion GO:0040017 186 0.390
negative regulation of developmental process GO:0051093 247 0.388
Fly
positive regulation of apoptotic process GO:0043065 246 0.386
positive regulation of intracellular protein transport GO:0090316 76 0.377
Human
organ morphogenesis GO:0009887 147 0.377
Worm
positive regulation of rho gtpase activity GO:0032321 56 0.376
post embryonic development GO:0009791 2 0.373
Fly
regulation of protein localization GO:0032880 296 0.370
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.362
Human
cardiac muscle cell contraction GO:0086003 4 0.359
single organism cell adhesion GO:0098602 179 0.358
Human
regulation of map kinase activity GO:0043405 108 0.358
collagen catabolic process GO:0030574 10 0.356
system process GO:0003008 349 0.351
Fly
skin development GO:0043588 76 0.349
Mouse
response to abiotic stimulus GO:0009628 336 0.338
cell morphogenesis GO:0000902 296 0.337
Human Mouse Fly
negative regulation of cellular amine metabolic process GO:0033239 3 0.337
neurogenesis GO:0022008 169 0.334
Fly
circulatory system development GO:0072359 262 0.331
circulatory system process GO:0003013 113 0.327
positive regulation of cellular component organization GO:0051130 376 0.327
Fly
lung alveolus development GO:0048286 4 0.327
positive regulation of transferase activity GO:0051347 227 0.327
regulation of transferase activity GO:0051338 355 0.317
hair follicle maturation GO:0048820 3 0.316
cell junction assembly GO:0034329 67 0.312
negative regulation of cellular component organization GO:0051129 235 0.312
regulation of cellular component biogenesis GO:0044087 281 0.303
regulation of actin filament based process GO:0032970 141 0.303
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.302
regulation of protein serine threonine kinase activity GO:0071900 179 0.301
modification dependent macromolecule catabolic process GO:0043632 212 0.299
sensory perception of smell GO:0007608 2 0.297
neuron projection morphogenesis GO:0048812 50 0.296
Fly
protein ubiquitination GO:0016567 314 0.293
inorganic ion transmembrane transport GO:0098660 231 0.289
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.287
positive regulation of programmed cell death GO:0043068 249 0.285
blood circulation GO:0008015 113 0.281
stress fiber assembly GO:0043149 40 0.280
i kappab kinase nf kappab signaling GO:0007249 166 0.279
Human
membrane protein ectodomain proteolysis GO:0006509 33 0.277
heart development GO:0007507 95 0.275
regulation of synaptic plasticity GO:0048167 3 0.274
regulation of protein binding GO:0043393 66 0.272
substrate adhesion dependent cell spreading GO:0034446 41 0.270
cardiac muscle contraction GO:0060048 34 0.268
protein localization to plasma membrane GO:0072659 93 0.266
regulation of cell differentiation GO:0045595 393 0.265
Fly
establishment of protein localization to membrane GO:0090150 121 0.264
regulation of protein localization to plasma membrane GO:1903076 40 0.263
associative learning GO:0008306 1 0.261
Fly
regulation of ubiquitin protein transferase activity GO:0051438 28 0.258
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.255
Human
action potential GO:0001508 34 0.255
regulation of cell motility GO:2000145 299 0.254
elastic fiber assembly GO:0048251 3 0.253
metal ion homeostasis GO:0055065 169 0.252
nervous system development GO:0007399 293 0.249
Fly
regulation of protein complex assembly GO:0043254 147 0.249
regulation of protein targeting GO:1903533 91 0.243
Human
positive regulation of cell motility GO:2000147 177 0.243
small gtpase mediated signal transduction GO:0007264 78 0.239
regulation of ligase activity GO:0051340 29 0.238
actin filament bundle organization GO:0061572 54 0.235
muscle system process GO:0003012 81 0.233
coagulation GO:0050817 78 0.230
Human
cell matrix adhesion GO:0007160 85 0.229
positive regulation of axon extension GO:0045773 4 0.225
regulation of rho protein signal transduction GO:0035023 79 0.224
regulation of anatomical structure morphogenesis GO:0022603 286 0.224
nucleoside triphosphate catabolic process GO:0009143 394 0.223
negative regulation of cell motility GO:2000146 104 0.217
hematopoietic or lymphoid organ development GO:0048534 186 0.215
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.214
actin filament bundle assembly GO:0051017 54 0.214
negative regulation of axonogenesis GO:0050771 4 0.214
membrane protein proteolysis GO:0033619 38 0.213
immune system development GO:0002520 195 0.212
Fly
synaptic vesicle exocytosis GO:0016079 3 0.212
protein import into nucleus GO:0006606 104 0.209
Human
neuron projection development GO:0031175 106 0.209
Fly
notch receptor processing GO:0007220 2 0.208
plasma membrane organization GO:0007009 115 0.207
protein localization to nucleus GO:0034504 136 0.207
Human
formation of primary germ layer GO:0001704 42 0.207
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.207
Fly
cellular metal ion homeostasis GO:0006875 146 0.204
negative regulation of cellular component movement GO:0051271 106 0.203
cilium organization GO:0044782 68 0.203
Human
collateral sprouting GO:0048668 2 0.201
cell projection organization GO:0030030 252 0.200
Human Fly
negative regulation of apoptotic signaling pathway GO:2001234 97 0.199
protein localization to cell surface GO:0034394 28 0.195
Human
myeloid cell differentiation GO:0030099 117 0.194
chemical homeostasis GO:0048878 306 0.191
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.190
cellular divalent inorganic cation homeostasis GO:0072503 128 0.184
actin filament based movement GO:0030048 17 0.183
response to hypoxia GO:0001666 96 0.183
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.180
nuclear import GO:0051170 106 0.180
Human
regulation of actin filament polymerization GO:0030833 50 0.179
ubiquitin dependent protein catabolic process GO:0006511 206 0.177
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.175
Human
positive regulation of cellular component movement GO:0051272 181 0.174
ion homeostasis GO:0050801 230 0.173
myosin filament assembly GO:0031034 2 0.173
regulation of gtpase activity GO:0043087 180 0.172
behavioral response to ethanol GO:0048149 2 0.172
Fly
blood vessel morphogenesis GO:0048514 162 0.171
negative regulation of organelle organization GO:0010639 126 0.169
cellular chemical homeostasis GO:0055082 180 0.168
response to oxygen levels GO:0070482 100 0.168
cellular ion homeostasis GO:0006873 168 0.168
acidic amino acid transport GO:0015800 6 0.166
cilium assembly GO:0042384 63 0.165
Human
cellular extravasation GO:0045123 21 0.165
taxis GO:0042330 157 0.162
Fly
endodermal cell differentiation GO:0035987 31 0.161
negative regulation of protein metabolic process GO:0051248 391 0.160
Human
negative regulation of kinase activity GO:0033673 106 0.160
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.158
actin mediated cell contraction GO:0070252 12 0.157
cerebral cortex neuron differentiation GO:0021895 1 0.157
divalent inorganic cation transport GO:0072511 158 0.155
nail development GO:0035878 3 0.154
cation homeostasis GO:0055080 189 0.154
copper ion import GO:0015677 1 0.152
salivary gland morphogenesis GO:0007435 4 0.150
regulation of cell morphogenesis GO:0022604 153 0.149
cellular calcium ion homeostasis GO:0006874 117 0.149
cell development GO:0048468 328 0.148
Mouse Fly
cytoplasmic transport GO:0016482 379 0.148
Human Fly
protein localization to organelle GO:0033365 280 0.145
Human
endoderm development GO:0007492 33 0.145
cell part morphogenesis GO:0032990 137 0.144
Human Fly
calcium independent cell matrix adhesion GO:0007161 1 0.142
negative regulation of neuron differentiation GO:0045665 21 0.142
cardiovascular system development GO:0072358 262 0.140
positive regulation of cell migration GO:0030335 172 0.140
negative regulation of catabolic process GO:0009895 104 0.140
Human
calcium ion homeostasis GO:0055074 122 0.139
response to oxidative stress GO:0006979 121 0.139
response to oxygen containing compound GO:1901700 369 0.138
Fly
cellular response to endogenous stimulus GO:0071495 336 0.138
maintenance of protein location GO:0045185 57 0.136
Human
cell projection morphogenesis GO:0048858 129 0.136
Human Fly
regulation of collagen metabolic process GO:0010712 15 0.136
regulation of intracellular transport GO:0032386 195 0.135
Human
establishment of protein localization to plasma membrane GO:0090002 68 0.135
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.135
regulation of metal ion transport GO:0010959 120 0.134
activation of mapkk activity GO:0000186 18 0.134
epidermis development GO:0008544 59 0.133
Mouse
establishment of protein localization to organelle GO:0072594 172 0.132
Human
negative regulation of protein catabolic process GO:0042177 59 0.131
Human
multicellular organismal metabolic process GO:0044236 34 0.130
uterus morphogenesis GO:0061038 2 0.130
Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.128
negative regulation of protein modification process GO:0031400 200 0.128
apoptotic signaling pathway GO:0097190 268 0.126
negative regulation of cell migration GO:0030336 102 0.126
modification dependent protein catabolic process GO:0019941 209 0.126
neuron differentiation GO:0030182 138 0.124
Fly
intracellular protein transport GO:0006886 270 0.124
Human
limb development GO:0060173 23 0.123
positive regulation of cellular catabolic process GO:0031331 284 0.123
regulation of protein localization to nucleus GO:1900180 85 0.122
Human
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.122
endomembrane system organization GO:0010256 196 0.122
regulation of purine nucleotide metabolic process GO:1900542 264 0.120
blood vessel endothelial cell migration GO:0043534 42 0.120
negative regulation of protein phosphorylation GO:0001933 140 0.120
beta amyloid metabolic process GO:0050435 12 0.119
divalent metal ion transport GO:0070838 152 0.119
cell chemotaxis GO:0060326 112 0.119
positive regulation of catabolic process GO:0009896 310 0.119
melanocyte differentiation GO:0030318 2 0.117
regulation of membrane potential GO:0042391 95 0.116
cation transport GO:0006812 331 0.116
anterior posterior axis specification GO:0009948 2 0.115
amyloid precursor protein catabolic process GO:0042987 12 0.115
hemopoiesis GO:0030097 180 0.113
Fly
regulation of intracellular protein transport GO:0033157 123 0.113
Human
signal transduction by phosphorylation GO:0023014 297 0.113
protein modification by small protein conjugation GO:0032446 342 0.112
g protein coupled receptor signaling pathway GO:0007186 207 0.111
Human
ion transmembrane transport GO:0034220 338 0.110
regulation of kinase activity GO:0043549 314 0.110
protein maturation GO:0051604 233 0.109
regulation of cellular component movement GO:0051270 334 0.109
negative regulation of cell differentiation GO:0045596 171 0.109
Fly
mitotic cell cycle process GO:1903047 286 0.108
Human Fly
tissue morphogenesis GO:0048729 96 0.108
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.108
protein targeting to nucleus GO:0044744 104 0.106
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.106
negative regulation of phosphorus metabolic process GO:0010563 267 0.105
positive regulation of homeostatic process GO:0032846 47 0.105
myeloid dendritic cell differentiation GO:0043011 3 0.104
maintenance of protein location in cell GO:0032507 56 0.104
Human
heart contraction GO:0060047 62 0.104
embryo development GO:0009790 123 0.104
Worm
generation of neurons GO:0048699 152 0.104
Fly
skeletal system development GO:0001501 79 0.103
negative regulation of cell projection organization GO:0031345 22 0.102
heart process GO:0003015 62 0.102
cell morphogenesis involved in differentiation GO:0000904 144 0.102
Mouse Fly
regulation of protein ubiquitination GO:0031396 95 0.101
cellular homeostasis GO:0019725 196 0.100
nuclear transport GO:0051169 179 0.100
Human
chemotaxis GO:0006935 157 0.099
Fly
nucleocytoplasmic transport GO:0006913 176 0.099
Human
positive regulation of organelle organization GO:0010638 195 0.098
Fly
regulation of axon guidance GO:1902667 3 0.097
regulation of cell projection organization GO:0031344 107 0.097
midgut development GO:0007494 1 0.097
negative regulation of hippo signaling GO:0035331 6 0.095
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.094
epithelial cell cell adhesion GO:0090136 7 0.094
positive regulation of rac gtpase activity GO:0032855 31 0.093
cytoplasmic sequestering of protein GO:0051220 12 0.093
Human
regulation of actin filament bundle assembly GO:0032231 36 0.093
establishment of organelle localization GO:0051656 59 0.092
cell cell signaling GO:0007267 155 0.091
central nervous system development GO:0007417 123 0.091
organelle assembly GO:0070925 176 0.090
Human
anion transport GO:0006820 161 0.090
cellular macromolecule catabolic process GO:0044265 380 0.090
divalent inorganic cation homeostasis GO:0072507 136 0.090
positive regulation of kinase activity GO:0033674 204 0.089
regulation of cellular response to stress GO:0080135 244 0.089
endothelial cell migration GO:0043542 86 0.089
negative regulation of cellular protein metabolic process GO:0032269 353 0.087
regulation of cell cycle GO:0051726 393 0.087
regulation of neurogenesis GO:0050767 82 0.087
regulation of apoptotic signaling pathway GO:2001233 175 0.086
cellular response to abiotic stimulus GO:0071214 117 0.086
regulation of protein polymerization GO:0032271 63 0.086
growth GO:0040007 202 0.086
protein processing GO:0016485 226 0.085
neuromuscular junction development GO:0007528 3 0.085
receptor recycling GO:0001881 15 0.084
muscle organ development GO:0007517 56 0.084
Mouse
adult locomotory behavior GO:0008344 1 0.084
response to decreased oxygen levels GO:0036293 96 0.084
cell migration involved in gastrulation GO:0042074 1 0.083
negative regulation of ligase activity GO:0051352 8 0.083
ribonucleoside catabolic process GO:0042454 406 0.082
regulation of multicellular organismal metabolic process GO:0044246 17 0.082
negative regulation of apoptotic process GO:0043066 316 0.082
positive regulation of developmental process GO:0051094 314 0.082
positive regulation of gtpase activity GO:0043547 166 0.082
forebrain generation of neurons GO:0021872 3 0.082
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.081
ribonucleoprotein complex assembly GO:0022618 78 0.081
sensory perception of chemical stimulus GO:0007606 38 0.081
hyperosmotic response GO:0006972 4 0.081
cellular response to hypoxia GO:0071456 51 0.080
jnk cascade GO:0007254 80 0.080
wound healing GO:0042060 115 0.080
Human
beta amyloid formation GO:0034205 7 0.079
extrinsic apoptotic signaling pathway GO:0097191 119 0.079
negative regulation of protein transport GO:0051224 75 0.079
Human
regulation of growth GO:0040008 165 0.079
single organism carbohydrate metabolic process GO:0044723 193 0.077
anatomical structure maturation GO:0071695 9 0.077
axon development GO:0061564 34 0.077
Fly
negative regulation of protein complex disassembly GO:0043242 20 0.077
calcium ion transport GO:0006816 147 0.077
negative regulation of intracellular signal transduction GO:1902532 183 0.076
pattern specification process GO:0007389 43 0.076
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.075
cilium morphogenesis GO:0060271 75 0.075
Human
cardiocyte differentiation GO:0035051 23 0.075
regulation of cell growth GO:0001558 135 0.073
carbohydrate metabolic process GO:0005975 207 0.073
desmosome assembly GO:0002159 4 0.073
actin filament polymerization GO:0030041 45 0.072
brain development GO:0007420 97 0.072
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.071
negative regulation of catalytic activity GO:0043086 335 0.071
protein targeting GO:0006605 187 0.071
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.071
regulation of receptor recycling GO:0001919 10 0.071
positive regulation of p38mapk cascade GO:1900745 8 0.070
maintenance of location in cell GO:0051651 62 0.070
Human
neural tube development GO:0021915 9 0.069
endocrine system development GO:0035270 26 0.069
sex determination GO:0007530 3 0.069
regulation of nucleocytoplasmic transport GO:0046822 98 0.068
Human
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.068
Fly
transcription factor import into nucleus GO:0042991 40 0.068
Human
hindbrain development GO:0030902 3 0.068
regulation of cellular component size GO:0032535 82 0.068
peptide metabolic process GO:0006518 51 0.067
organic anion transport GO:0015711 103 0.067
regulation of nucleotide catabolic process GO:0030811 205 0.067
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.066
positive regulation of coagulation GO:0050820 11 0.066
posttranscriptional regulation of gene expression GO:0010608 213 0.066
Human
head development GO:0060322 108 0.065
positive regulation of cell death GO:0010942 263 0.065
cytoplasmic mrna processing body assembly GO:0033962 10 0.065
regulation of cell shape GO:0008360 48 0.065
regulation of cardiac muscle contraction GO:0055117 33 0.065
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.065
regulation of ion transport GO:0043269 189 0.065
embryonic morphogenesis GO:0048598 85 0.065
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.065
morphogenesis of an epithelium GO:0002009 60 0.064
Fly
rho protein signal transduction GO:0007266 26 0.064
isg15 protein conjugation GO:0032020 5 0.064
negative regulation of protein binding GO:0032091 35 0.064
leukocyte migration GO:0050900 107 0.063
regulation of binding GO:0051098 111 0.063
cytokinesis GO:0000910 96 0.063
regulation of cytoplasmic transport GO:1903649 149 0.062
Human
regulation of peptidase activity GO:0052547 180 0.062
negative regulation of phosphorylation GO:0042326 174 0.062
integrin activation GO:0033622 8 0.062
regulation of establishment of protein localization GO:0070201 242 0.061
Human
nitrogen compound transport GO:0071705 191 0.061
regulation of actin filament length GO:0030832 56 0.061
negative regulation of protein maturation GO:1903318 142 0.061
response to light stimulus GO:0009416 87 0.061
myosin filament organization GO:0031033 2 0.061
proteasomal protein catabolic process GO:0010498 176 0.061
positive regulation of hydrolase activity GO:0051345 331 0.060
positive regulation of stress activated mapk cascade GO:0032874 60 0.060
chromatin organization GO:0006325 351 0.060
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.059
Human
positive regulation of transport GO:0051050 336 0.059
Human
ras protein signal transduction GO:0007265 73 0.058
regulation of nervous system development GO:0051960 88 0.058
regulation of stress activated mapk cascade GO:0032872 84 0.058
neuron development GO:0048666 113 0.058
Fly
microtubule based process GO:0007017 210 0.058
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.058
blood vessel development GO:0001568 172 0.058
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.058
immune response GO:0006955 307 0.058
regulation of rho gtpase activity GO:0032319 66 0.057
nucleoside catabolic process GO:0009164 408 0.057
nucleoside triphosphate metabolic process GO:0009141 422 0.057
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.057
response to salt stress GO:0009651 3 0.057
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.056
cellular amide metabolic process GO:0043603 69 0.056
positive regulation of cellular amine metabolic process GO:0033240 7 0.056
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.056
striated muscle myosin thick filament assembly GO:0071688 2 0.055
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.055
glycosyl compound catabolic process GO:1901658 413 0.055
regulation of protein transport GO:0051223 213 0.054
Human
muscle cell differentiation GO:0042692 63 0.054
protein glycosylation GO:0006486 62 0.054
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.054
single organism membrane organization GO:0044802 268 0.054
Human
dephosphorylation GO:0016311 209 0.054
glycoprotein biosynthetic process GO:0009101 91 0.053
regulation of extent of cell growth GO:0061387 9 0.053
regulation of cell cell adhesion GO:0022407 57 0.053
protein polymerization GO:0051258 71 0.052
positive regulation of cytoplasmic transport GO:1903651 82 0.051
Human
protein depolymerization GO:0051261 30 0.051
canonical wnt signaling pathway GO:0060070 116 0.050
cellular component assembly involved in morphogenesis GO:0010927 73 0.050
Human
neurotransmitter secretion GO:0007269 4 0.050
oocyte differentiation GO:0009994 2 0.049
cellular protein complex assembly GO:0043623 188 0.049
regulation of actin polymerization or depolymerization GO:0008064 56 0.049
mitotic cell cycle GO:0000278 326 0.049
Human Fly
visual learning GO:0008542 1 0.048
positive regulation of receptor recycling GO:0001921 5 0.048
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.048

FLNB disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.991
myopathy DOID:423 104 0.960
Human
muscular disease DOID:0080000 114 0.960
Human
heart disease DOID:114 68 0.960
cardiomyopathy DOID:0050700 50 0.960
dilated cardiomyopathy DOID:12930 32 0.960
intrinsic cardiomyopathy DOID:0060036 50 0.960
musculoskeletal system disease DOID:17 223 0.960
muscle tissue disease DOID:66 113 0.960
Human
skin disease DOID:37 33 0.625
integumentary system disease DOID:16 43 0.625
disease of mental health DOID:150 70 0.328
dementia DOID:1307 19 0.313
alzheimer s disease DOID:10652 16 0.313
central nervous system disease DOID:331 186 0.313
tauopathy DOID:680 16 0.313
neurodegenerative disease DOID:1289 102 0.313
nervous system disease DOID:863 431 0.313
cognitive disorder DOID:1561 29 0.313
physical disorder DOID:0080015 41 0.147
Human
congenital nervous system abnormality DOID:2490 21 0.147
Human
muscular dystrophy DOID:9884 51 0.128
Human
emery dreifuss muscular dystrophy DOID:11726 6 0.128
kidney disease DOID:557 36 0.088
urinary system disease DOID:18 40 0.088
brain disease DOID:936 73 0.063
neuropathy DOID:870 52 0.054
neuromuscular disease DOID:440 38 0.048