Homo sapiens

169 known processes

FOXO1

forkhead box O1

(Aliases: FOXO1A,FKH1,FKHR)

FOXO1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.948
Human Mouse
cellular response to endogenous stimulus GO:0071495 336 0.840
Human Mouse Worm Fly
blood vessel development GO:0001568 172 0.657
Human Mouse
positive regulation of feeding behavior GO:2000253 1 0.619
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.592
response to hormone GO:0009725 175 0.566
Human Mouse Worm Fly
oogenesis GO:0048477 2 0.562
regulation of cell differentiation GO:0045595 393 0.559
Human Mouse Fly
single organism carbohydrate metabolic process GO:0044723 193 0.531
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.512
Mouse
nervous system development GO:0007399 293 0.429
Fly
positive regulation of developmental process GO:0051094 314 0.426
Human
negative regulation of apoptotic process GO:0043066 316 0.408
cellular ketone metabolic process GO:0042180 80 0.390
Mouse
positive regulation of programmed cell death GO:0043068 249 0.389
organ induction GO:0001759 4 0.379
female gamete generation GO:0007292 2 0.345
regulation of feeding behavior GO:0060259 3 0.337
Fly
negative regulation of cell differentiation GO:0045596 171 0.327
Human Mouse Fly
regulation of smooth muscle cell differentiation GO:0051150 3 0.326
Human
regulation of carbohydrate metabolic process GO:0006109 54 0.323
Mouse
response to oxygen containing compound GO:1901700 369 0.308
Human Mouse Worm Fly
positive regulation of cell death GO:0010942 263 0.304
amine metabolic process GO:0009308 44 0.299
negative regulation of cell death GO:0060548 345 0.297
cellular response to nitrogen compound GO:1901699 144 0.292
Human Mouse Worm Fly
positive regulation of erythrocyte differentiation GO:0045648 11 0.289
Human
positive regulation of catabolic process GO:0009896 310 0.268
blood vessel morphogenesis GO:0048514 162 0.266
Human
immune system development GO:0002520 195 0.263
Human
negative regulation of cell fate commitment GO:0010454 3 0.259
cardiovascular system development GO:0072358 262 0.251
Human Mouse
cellular response to hormone stimulus GO:0032870 125 0.249
Human Mouse Worm Fly
epithelial cell differentiation GO:0030855 141 0.246
cellular response to oxygen containing compound GO:1901701 276 0.242
Human Mouse Worm Fly
regulation of cell cycle process GO:0010564 266 0.242
Human Worm
cellular amino acid metabolic process GO:0006520 116 0.235
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.233
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.231
carbon catabolite activation of transcription GO:0045991 3 0.230
hematopoietic or lymphoid organ development GO:0048534 186 0.230
Human
positive regulation of glucocorticoid receptor signaling pathway GO:2000324 1 0.221
regulation of cell cycle GO:0051726 393 0.221
Human Worm
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.215
hemopoiesis GO:0030097 180 0.213
Human
negative regulation of phosphorylation GO:0042326 174 0.212
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.211
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.201
cellular response to nutrient levels GO:0031669 69 0.200
response to organic cyclic compound GO:0014070 204 0.200
response to steroid hormone GO:0048545 80 0.198
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.197
Human Mouse Worm Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.195
somatic muscle development GO:0007525 1 0.195
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.194
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.193
positive regulation of cell proliferation GO:0008284 301 0.187
enzyme linked receptor protein signaling pathway GO:0007167 303 0.186
Human Mouse Worm Fly
multicellular organismal aging GO:0010259 3 0.186
Worm Fly
negative regulation of developmental process GO:0051093 247 0.183
Human Mouse Worm Fly
vasculature development GO:0001944 181 0.182
Human Mouse
response to peptide GO:1901652 65 0.179
Human Mouse Worm Fly
covalent chromatin modification GO:0016569 254 0.179
cellular response to dna damage stimulus GO:0006974 379 0.179
Mouse Worm Fly
erythrocyte differentiation GO:0030218 28 0.177
Human
organ formation GO:0048645 3 0.177
response to abiotic stimulus GO:0009628 336 0.176
positive regulation of cell differentiation GO:0045597 211 0.175
Human
positive regulation of transcription by galactose GO:0000411 1 0.173
myeloid cell differentiation GO:0030099 117 0.169
Human
cell development GO:0048468 328 0.166
Mouse Fly
negative regulation of protein metabolic process GO:0051248 391 0.161
embryonic morphogenesis GO:0048598 85 0.161
cellular amine metabolic process GO:0044106 41 0.161
mitotic cell cycle GO:0000278 326 0.159
histone acetylation GO:0016573 93 0.157
cellular carbohydrate metabolic process GO:0044262 84 0.156
Mouse Fly
histone modification GO:0016570 251 0.155
response to extracellular stimulus GO:0009991 85 0.153
oocyte differentiation GO:0009994 2 0.151
regulation of autophagy GO:0010506 52 0.150
tube development GO:0035295 125 0.149
regulation of transcription by galactose GO:0000409 1 0.147
chromatin modification GO:0016568 298 0.144
digestive system development GO:0055123 75 0.143
regulation of cytokine production GO:0001817 232 0.143
post embryonic development GO:0009791 2 0.140
Worm Fly
positive regulation of cellular component organization GO:0051130 376 0.140
extrinsic apoptotic signaling pathway GO:0097191 119 0.138
g protein coupled receptor signaling pathway GO:0007186 207 0.138
Fly
purine ribonucleotide biosynthetic process GO:0009152 79 0.136
Fly
regulation of vasculature development GO:1901342 97 0.135
Human
stem cell differentiation GO:0048863 93 0.129
Human Mouse Fly
regulation of cell development GO:0060284 161 0.128
histone h4 acetylation GO:0043967 47 0.127
positive regulation of apoptotic process GO:0043065 246 0.125
cellular component morphogenesis GO:0032989 314 0.125
Fly
chromatin organization GO:0006325 351 0.124
negative regulation of phosphorus metabolic process GO:0010563 267 0.123
regulation of angiogenesis GO:0045765 92 0.123
Human
negative regulation of cell fate specification GO:0009996 3 0.122
response to bacterium GO:0009617 144 0.122
Worm Fly
response to lipid GO:0033993 206 0.121
positive regulation of protein phosphorylation GO:0001934 313 0.121
epithelium development GO:0060429 227 0.120
response to organonitrogen compound GO:0010243 156 0.120
Human Mouse Worm Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.119
muscle structure development GO:0061061 98 0.118
Human Fly
cellular response to organonitrogen compound GO:0071417 124 0.117
Human Mouse Worm Fly
angiogenesis GO:0001525 147 0.117
Human
apoptotic signaling pathway GO:0097190 268 0.117
anatomical structure formation involved in morphogenesis GO:0048646 284 0.116
Human Fly
regulation of organ formation GO:0003156 4 0.115
somatic stem cell maintenance GO:0035019 4 0.115
monosaccharide metabolic process GO:0005996 74 0.113
Mouse
positive regulation of cell migration GO:0030335 172 0.113
response to cytokine GO:0034097 232 0.112
positive regulation of locomotion GO:0040017 186 0.112
internal protein amino acid acetylation GO:0006475 101 0.112
peptidyl lysine modification GO:0018205 144 0.111
lipid localization GO:0010876 106 0.110
Fly
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.109
ribonucleoside triphosphate metabolic process GO:0009199 412 0.109
positive regulation of phosphorylation GO:0042327 394 0.109
cellular response to growth factor stimulus GO:0071363 197 0.108
regulation of homeostatic process GO:0032844 121 0.108
Human
oocyte development GO:0048599 1 0.107
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.107
energy reserve metabolic process GO:0006112 22 0.107
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.106
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.106
chemical homeostasis GO:0048878 306 0.106
Mouse Fly
regulation of myeloid cell differentiation GO:0045637 81 0.105
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.105
regulation of kinase activity GO:0043549 314 0.104
mapk cascade GO:0000165 288 0.104
response to decreased oxygen levels GO:0036293 96 0.104
negative regulation of programmed cell death GO:0043069 321 0.104
hindbrain development GO:0030902 3 0.101
intracellular estrogen receptor signaling pathway GO:0030520 23 0.100
organophosphate catabolic process GO:0046434 430 0.100
mitotic cell cycle process GO:1903047 286 0.099
positive regulation of mapk cascade GO:0043410 190 0.098
regulation of activin receptor signaling pathway GO:0032925 14 0.098
Fly
response to nitrogen compound GO:1901698 184 0.097
Human Mouse Worm Fly
cell morphogenesis GO:0000902 296 0.096
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.096
Fly
carbohydrate metabolic process GO:0005975 207 0.096
Mouse Fly
embryonic placenta development GO:0001892 1 0.095
locomotory behavior GO:0007626 1 0.093
Fly
cellular polysaccharide metabolic process GO:0044264 27 0.093
Fly
protein acetylation GO:0006473 116 0.093
response to hyperoxia GO:0055093 4 0.092
embryonic hemopoiesis GO:0035162 4 0.091
gtp metabolic process GO:0046039 239 0.091
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.090
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.090
Fly
cell projection organization GO:0030030 252 0.090
Fly
cellular response to starvation GO:0009267 58 0.089
ribonucleotide biosynthetic process GO:0009260 81 0.089
Fly
regulation of protein kinase activity GO:0045859 289 0.089
maintenance of location GO:0051235 112 0.088
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.086
Human Worm Fly
negative regulation of wnt signaling pathway GO:0030178 69 0.086
Mouse
circulatory system development GO:0072359 262 0.084
Human Mouse
biological adhesion GO:0022610 331 0.084
response to oxygen levels GO:0070482 100 0.083
response to nutrient levels GO:0031667 81 0.082
positive regulation of neural precursor cell proliferation GO:2000179 2 0.082
protein import GO:0017038 130 0.082
regulation of mitotic cell cycle GO:0007346 189 0.080
specification of organ identity GO:0010092 3 0.080
cellular glucan metabolic process GO:0006073 22 0.079
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.079
regulation of cell growth GO:0001558 135 0.079
Fly
response to estrogen GO:0043627 47 0.079
positive regulation of autophagy GO:0010508 24 0.078
oxidation reduction process GO:0055114 396 0.078
Fly
protein modification by small protein conjugation GO:0032446 342 0.077
protein acylation GO:0043543 138 0.076
lipid metabolic process GO:0006629 381 0.076
Worm Fly
regulation of stress activated mapk cascade GO:0032872 84 0.075
ribose phosphate biosynthetic process GO:0046390 82 0.074
Fly
ovulation cycle GO:0042698 9 0.074
camp biosynthetic process GO:0006171 47 0.074
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.073
mating GO:0007618 1 0.073
gland development GO:0048732 48 0.072
myoblast fusion GO:0007520 1 0.072
Fly
determination of adult lifespan GO:0008340 2 0.071
Worm Fly
cellular response to oxidative stress GO:0034599 85 0.071
Mouse Fly
cell activation GO:0001775 213 0.071
reproductive process GO:0022414 106 0.071
protein catabolic process GO:0030163 325 0.070
cellular lipid metabolic process GO:0044255 303 0.069
cellular response to hydrogen peroxide GO:0070301 37 0.069
sex determination GO:0007530 3 0.069
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.068
nucleotide biosynthetic process GO:0009165 109 0.068
Fly
regulation of cell motility GO:2000145 299 0.068
response to external biotic stimulus GO:0043207 261 0.067
Worm Fly
rhythmic behavior GO:0007622 2 0.067
Fly
regulation of protein localization GO:0032880 296 0.066
cerebellum development GO:0021549 2 0.066
nucleotide catabolic process GO:0009166 408 0.066
leukocyte migration GO:0050900 107 0.066
male genitalia development GO:0030539 1 0.066
canonical wnt signaling pathway GO:0060070 116 0.065
Mouse
system process GO:0003008 349 0.065
protein import into nucleus GO:0006606 104 0.064
intracellular receptor signaling pathway GO:0030522 104 0.064
fatty acid metabolic process GO:0006631 115 0.064
negative regulation of cellular component organization GO:0051129 235 0.064
rna processing GO:0006396 255 0.064
proteasomal protein catabolic process GO:0010498 176 0.063
generation of neurons GO:0048699 152 0.063
Fly
regulation of epithelial cell differentiation GO:0030856 24 0.063
positive regulation of cellular response to insulin stimulus GO:1900078 6 0.063
Fly
response to radiation GO:0009314 151 0.063
Worm
regulation of reactive oxygen species metabolic process GO:2000377 41 0.063
Mouse
single organism cellular localization GO:1902580 332 0.063
autophagy GO:0006914 88 0.063
regulation of ossification GO:0030278 58 0.063
response to glucagon GO:0033762 1 0.062
dephosphorylation GO:0016311 209 0.062
regulation of cellular response to stress GO:0080135 244 0.062
glycosyl compound catabolic process GO:1901658 413 0.062
memory GO:0007613 3 0.062
establishment of protein localization to organelle GO:0072594 172 0.062
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.061
transmembrane transport GO:0055085 399 0.061
negative regulation of cell growth GO:0030308 83 0.060
Fly
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.060
positive regulation of cell motility GO:2000147 177 0.060
positive regulation of nucleoside metabolic process GO:0045979 186 0.060
negative regulation of cell proliferation GO:0008285 228 0.059
Human Fly
internal peptidyl lysine acetylation GO:0018393 97 0.059
negative regulation of apoptotic signaling pathway GO:2001234 97 0.059
negative regulation of catalytic activity GO:0043086 335 0.059
single organism reproductive process GO:0044702 98 0.059
neurological system process GO:0050877 163 0.059
neurogenesis GO:0022008 169 0.059
Fly
regulation of multi organism process GO:0043900 157 0.059
response to other organism GO:0051707 261 0.058
Worm Fly
regulation of cell adhesion GO:0030155 166 0.058
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.058
Mouse
methylation GO:0032259 106 0.058
positive regulation of cell cycle GO:0045787 140 0.058
glucose metabolic process GO:0006006 45 0.058
Mouse
organonitrogen compound biosynthetic process GO:1901566 200 0.058
Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.058
positive regulation of myeloid cell differentiation GO:0045639 39 0.058
Human
organic hydroxy compound metabolic process GO:1901615 147 0.057
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.057
regulation of response to external stimulus GO:0032101 222 0.057
Fly
endodermal cell fate specification GO:0001714 4 0.057
blastoderm segmentation GO:0007350 2 0.057
heart formation GO:0060914 2 0.057
cellular response to oxygen levels GO:0071453 55 0.057
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.057
regulation of muscle cell differentiation GO:0051147 31 0.057
Human
urogenital system development GO:0001655 65 0.056
wnt signaling pathway GO:0016055 156 0.056
Mouse
protein oligomerization GO:0051259 173 0.056
purine nucleotide biosynthetic process GO:0006164 84 0.056
Fly
regulation of apoptotic signaling pathway GO:2001233 175 0.056
cellular response to extracellular stimulus GO:0031668 72 0.056
leukocyte activation GO:0045321 164 0.055
hormone mediated signaling pathway GO:0009755 22 0.055
lung alveolus development GO:0048286 4 0.055
regulation of transferase activity GO:0051338 355 0.055
steroid metabolic process GO:0008202 94 0.055
neuron differentiation GO:0030182 138 0.054
Fly
growth GO:0040007 202 0.054
Worm Fly
purine ribonucleoside metabolic process GO:0046128 437 0.054
cellular lipid catabolic process GO:0044242 65 0.053
membrane organization GO:0061024 292 0.053
negative regulation of blood vessel morphogenesis GO:2000181 41 0.053
Human
peptidyl lysine acetylation GO:0018394 101 0.053
syncytium formation by plasma membrane fusion GO:0000768 2 0.053
Fly
regulation of transmembrane transport GO:0034762 139 0.053
macroautophagy GO:0016236 39 0.052
Fly
cyclic nucleotide biosynthetic process GO:0009190 61 0.052
Fly
lung epithelial cell differentiation GO:0060487 1 0.052
nitrogen cycle metabolic process GO:0071941 3 0.051
monocarboxylic acid metabolic process GO:0032787 185 0.051
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.051
regulation of locomotion GO:0040012 329 0.051
cell adhesion GO:0007155 325 0.050
negative regulation of smooth muscle cell differentiation GO:0051151 2 0.050
Human
ossification GO:0001503 121 0.050
anion transport GO:0006820 161 0.049
stem cell division GO:0017145 2 0.049
oocyte maturation GO:0001556 1 0.049
regulation of establishment of protein localization GO:0070201 242 0.048
lipid biosynthetic process GO:0008610 177 0.048
Worm
hemoglobin biosynthetic process GO:0042541 3 0.048
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.047
regulation of endothelial cell differentiation GO:0045601 4 0.047
neuroblast proliferation GO:0007405 4 0.047
mitotic cell cycle phase transition GO:0044772 162 0.047
translation GO:0006412 132 0.046
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
heart development GO:0007507 95 0.046
regulation of growth GO:0040008 165 0.046
Worm Fly
positive regulation of protein catabolic process GO:0045732 75 0.046
t cell differentiation in thymus GO:0033077 4 0.046
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.045
purine nucleotide catabolic process GO:0006195 405 0.045
peptidyl tyrosine phosphorylation GO:0018108 170 0.045
response to estradiol GO:0032355 23 0.045
response to genistein GO:0033595 1 0.045
cellular response to increased oxygen levels GO:0036295 4 0.045
small molecule biosynthetic process GO:0044283 157 0.045
cell growth GO:0016049 160 0.044
Fly
striated muscle contraction GO:0006941 52 0.044
central nervous system development GO:0007417 123 0.044
negative regulation of angiogenesis GO:0016525 39 0.044
Human
regulation of wnt signaling pathway GO:0030111 123 0.044
Mouse
negative regulation of lipid transport GO:0032369 18 0.043
positive regulation of nucleotide catabolic process GO:0030813 185 0.043
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.043
microtubule based process GO:0007017 210 0.043
Fly
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.042
regulation of canonical wnt signaling pathway GO:0060828 88 0.042
Mouse
positive regulation of hormone biosynthetic process GO:0046886 4 0.042
cellular response to external stimulus GO:0071496 111 0.042
negative regulation of phosphate metabolic process GO:0045936 267 0.042
epithelial cell proliferation GO:0050673 128 0.042
ectoderm development GO:0007398 3 0.042
cell part morphogenesis GO:0032990 137 0.041
Fly
prostate gland morphogenesis GO:0060512 1 0.041
lipid transport GO:0006869 90 0.041
atp metabolic process GO:0046034 176 0.041
ribonucleotide catabolic process GO:0009261 405 0.041
organic anion transport GO:0015711 103 0.041
negative regulation of epithelial cell proliferation GO:0050680 48 0.041
cell type specific apoptotic process GO:0097285 125 0.041
Human
positive regulation of immune system process GO:0002684 283 0.040
Human Worm
embryo development GO:0009790 123 0.040
positive regulation of gliogenesis GO:0014015 4 0.040
regulation of anatomical structure morphogenesis GO:0022603 286 0.040
Human
ion transmembrane transport GO:0034220 338 0.040
trabecula morphogenesis GO:0061383 2 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.040
leukocyte differentiation GO:0002521 98 0.039
regulation of mapk cascade GO:0043408 262 0.039
anterior posterior axis specification GO:0009948 2 0.039
positive regulation of hydrolase activity GO:0051345 331 0.039
muscle system process GO:0003012 81 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.039
response to hypoxia GO:0001666 96 0.038
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.038
protein ubiquitination GO:0016567 314 0.038
osteoblast differentiation GO:0001649 92 0.038
positive regulation of cellular component movement GO:0051272 181 0.038
cholesterol transport GO:0030301 39 0.038
reactive oxygen species biosynthetic process GO:1903409 4 0.038
skin development GO:0043588 76 0.037
regulation of neuron apoptotic process GO:0043523 35 0.037
Human
cellular response to lipid GO:0071396 127 0.037
respiratory tube development GO:0030323 20 0.037
positive regulation of immune response GO:0050778 159 0.037
Worm
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.037
development of primary female sexual characteristics GO:0046545 10 0.037
cellular response to hyperoxia GO:0071455 4 0.037
ameboidal type cell migration GO:0001667 135 0.037
macromolecule methylation GO:0043414 97 0.037
hexose metabolic process GO:0019318 55 0.036
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.036
Fly
regulation of protein localization to plasma membrane GO:1903076 40 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
positive regulation of epithelial cell differentiation GO:0030858 14 0.036
dna repair GO:0006281 198 0.036
chordate embryonic development GO:0043009 34 0.036
camp metabolic process GO:0046058 61 0.036
Fly
protein localization to membrane GO:0072657 160 0.035
regulation of cell migration GO:0030334 289 0.035
response to drug GO:0042493 81 0.035
immune response GO:0006955 307 0.035
Worm
regulation of epidermis development GO:0045682 19 0.035
nucleocytoplasmic transport GO:0006913 176 0.035
sulfur compound metabolic process GO:0006790 101 0.035
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.035
negative regulation of cell size GO:0045792 3 0.035
Fly
positive regulation of mitotic cell cycle GO:0045931 60 0.035
cell cycle arrest GO:0007050 71 0.035
Human
behavior GO:0007610 112 0.035
Fly
nuclear import GO:0051170 106 0.035
response to oxidative stress GO:0006979 121 0.035
Mouse Fly
regulation of cellular component movement GO:0051270 334 0.034
small molecule catabolic process GO:0044282 92 0.034
cell projection morphogenesis GO:0048858 129 0.034
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.034
Mouse
regeneration GO:0031099 4 0.034
circulatory system process GO:0003013 113 0.033
negative regulation of erythrocyte differentiation GO:0045647 3 0.033
sterol transport GO:0015918 39 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
cellular response to organic cyclic compound GO:0071407 127 0.033
cellular response to glucocorticoid stimulus GO:0071385 4 0.033
androgen receptor signaling pathway GO:0030521 34 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.033
regulation of cardioblast differentiation GO:0051890 4 0.033
cytoplasmic transport GO:0016482 379 0.033
protein targeting GO:0006605 187 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.032
signal transduction by phosphorylation GO:0023014 297 0.032
cell cell signaling GO:0007267 155 0.032
protein deacetylation GO:0006476 38 0.032
positive regulation of neuroblast proliferation GO:0002052 2 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
brain development GO:0007420 97 0.032
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.032
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
mrna metabolic process GO:0016071 175 0.032
rho protein signal transduction GO:0007266 26 0.032
pattern specification process GO:0007389 43 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.032
negative regulation of g0 to g1 transition GO:0070317 2 0.032
Human
nerve development GO:0021675 4 0.031
regulation of epithelial cell proliferation GO:0050678 113 0.031
regulation of lipid biosynthetic process GO:0046890 47 0.031
Worm
glycoprotein biosynthetic process GO:0009101 91 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
muscle cell differentiation GO:0042692 63 0.031
Human Fly
positive regulation of ras gtpase activity GO:0032320 117 0.031
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
cell cycle phase transition GO:0044770 173 0.030
digestive tract morphogenesis GO:0048546 56 0.030
negative regulation of locomotion GO:0040013 118 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.030
regulation of intracellular protein transport GO:0033157 123 0.030
secretion GO:0046903 254 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.030
response to biotic stimulus GO:0009607 276 0.030
Worm Fly
single organism membrane organization GO:0044802 268 0.030
developmental growth GO:0048589 48 0.030
Worm Fly
regulation of ion transmembrane transport GO:0034765 132 0.030
intracellular protein transport GO:0006886 270 0.030
n terminal protein amino acid modification GO:0031365 13 0.030
energy derivation by oxidation of organic compounds GO:0015980 43 0.030
Fly
cellular response to peptide GO:1901653 59 0.030
Human Mouse Worm Fly
cellular response to reactive oxygen species GO:0034614 50 0.029
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.029
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
protein localization to nucleus GO:0034504 136 0.029
myeloid leukocyte differentiation GO:0002573 60 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.029
cellular response to decreased oxygen levels GO:0036294 51 0.029
mammary gland morphogenesis GO:0060443 2 0.029
mammary gland development GO:0030879 17 0.029
hindlimb morphogenesis GO:0035137 2 0.028
glycerolipid metabolic process GO:0046486 107 0.028
regulation of rho protein signal transduction GO:0035023 79 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
posttranscriptional regulation of gene expression GO:0010608 213 0.028
Human
negative regulation of stem cell differentiation GO:2000737 22 0.028
regulation of body fluid levels GO:0050878 99 0.028
negative regulation of protein modification process GO:0031400 200 0.028
myeloid cell homeostasis GO:0002262 34 0.028
Human
response to nutrient GO:0007584 20 0.028
negative regulation of gliogenesis GO:0014014 3 0.028
metencephalon development GO:0022037 2 0.028
nuclear transport GO:0051169 179 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
regulation of gtpase activity GO:0043087 180 0.028
secretion by cell GO:0032940 226 0.027
cardiac muscle tissue development GO:0048738 39 0.027
epidermal cell differentiation GO:0009913 45 0.027
reproductive structure development GO:0048608 55 0.027
salivary gland morphogenesis GO:0007435 4 0.027
protein localization to organelle GO:0033365 280 0.027
cell proliferation in forebrain GO:0021846 1 0.027
blastocyst development GO:0001824 3 0.027
neuroendocrine cell differentiation GO:0061101 2 0.027
female gonad development GO:0008585 10 0.027

FOXO1 disease predictions

Disease DO term ID Size Probability Func Analog Org
gonadal disease DOID:2277 8 0.246
endocrine system disease DOID:28 26 0.246
reproductive system disease DOID:15 17 0.246
disease of metabolism DOID:0014667 295 0.093
inherited metabolic disorder DOID:655 242 0.093
musculoskeletal system disease DOID:17 223 0.069
cancer DOID:162 167 0.061
disease of cellular proliferation DOID:14566 174 0.061
central nervous system disease DOID:331 186 0.042
nervous system disease DOID:863 431 0.042
organ system cancer DOID:0050686 164 0.041
neurodegenerative disease DOID:1289 102 0.039