|
regulation of neuron differentiation
|
GO:0045664 |
70 |
1.000
|
Human Mouse |
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
Human |
|
neuron projection development
|
GO:0031175 |
106 |
1.000
|
Human Mouse Fly |
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
1.000
|
Human |
|
actin filament organization
|
GO:0007015 |
128 |
1.000
|
Human Fly |
|
cell projection organization
|
GO:0030030 |
252 |
1.000
|
Human Mouse Fly |
|
cell development
|
GO:0048468 |
328 |
1.000
|
Human Mouse Fly |
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
1.000
|
Human |
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
1.000
|
Human Rat |
|
positive regulation of developmental process
|
GO:0051094 |
314 |
1.000
|
Human Mouse |
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
1.000
|
Human |
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
Human Zebrafish Fly |
|
regulation of neuron projection development
|
GO:0010975 |
57 |
1.000
|
Human Mouse |
|
neurogenesis
|
GO:0022008 |
169 |
1.000
|
Human Mouse Fly |
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
1.000
|
Mouse Fly |
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
1.000
|
Human |
|
regulation of neurogenesis
|
GO:0050767 |
82 |
1.000
|
Human Mouse |
|
regulation of locomotion
|
GO:0040012 |
329 |
1.000
|
Human |
|
regulation of actin filament based process
|
GO:0032970 |
141 |
1.000
|
Human Fly |
|
chemotaxis
|
GO:0006935 |
157 |
1.000
|
Fly |
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
1.000
|
Human |
|
positive regulation of cell development
|
GO:0010720 |
92 |
1.000
|
Human Mouse |
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.999
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.999
|
Fly |
|
regulation of cell migration
|
GO:0030334 |
289 |
0.999
|
Human |
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.999
|
Human |
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.999
|
Human Fly |
|
epithelial cell migration
|
GO:0010631 |
119 |
0.999
|
Human |
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.999
|
Human |
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.999
|
Rat |
|
actin filament based process
|
GO:0030029 |
224 |
0.999
|
Human Fly |
|
stress fiber assembly
|
GO:0043149 |
40 |
0.999
|
Human |
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.999
|
Human |
|
generation of neurons
|
GO:0048699 |
152 |
0.998
|
Human Mouse Fly |
|
neuron differentiation
|
GO:0030182 |
138 |
0.998
|
Human Mouse Fly |
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.998
|
Human Mouse |
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.998
|
Human |
|
cell cell junction organization
|
GO:0045216 |
69 |
0.998
|
Fly |
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.998
|
Human Fly |
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.998
|
Human Rat |
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.998
|
Human Mouse |
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.998
|
Human Mouse |
|
amine metabolic process
|
GO:0009308 |
44 |
0.998
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.997
|
Human Mouse Fly |
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.997
|
Human |
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.997
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.997
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.997
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.997
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.997
|
Worm |
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.996
|
Human |
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.996
|
Human |
|
cell junction assembly
|
GO:0034329 |
67 |
0.996
|
Fly |
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.996
|
Human |
|
regulation of cell development
|
GO:0060284 |
161 |
0.996
|
Human Mouse |
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.996
|
Human |
|
regulation of cell motility
|
GO:2000145 |
299 |
0.996
|
Human |
|
long term memory
|
GO:0007616 |
2 |
0.996
|
Fly |
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.996
|
Human Mouse Fly |
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.996
|
Fly |
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.996
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.996
|
Human |
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.996
|
Fly |
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.996
|
Human Mouse |
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.995
|
Human |
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.995
|
Human Mouse |
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.995
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.994
|
Human |
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.994
|
Worm |
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.994
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.993
|
Rat |
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.993
|
Human |
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.992
|
Human |
|
cell morphogenesis
|
GO:0000902 |
296 |
0.992
|
Human Mouse Fly |
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.992
|
Human |
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.992
|
Human |
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.991
|
Fly |
|
cell adhesion
|
GO:0007155 |
325 |
0.991
|
Human Fly |
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.990
|
Human Mouse |
|
ion homeostasis
|
GO:0050801 |
230 |
0.990
|
Human |
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.990
|
Human |
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.990
|
Mouse Fly |
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.989
|
Human Mouse |
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.989
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.989
|
Human |
|
endocytosis
|
GO:0006897 |
159 |
0.989
|
Human |
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.989
|
Fly |
|
cell junction organization
|
GO:0034330 |
79 |
0.988
|
Fly |
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.988
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.988
|
Fly |
|
mapk cascade
|
GO:0000165 |
288 |
0.988
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.987
|
Human Mouse Rat |
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.987
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.987
|
Human Rat |
|
actin filament polymerization
|
GO:0030041 |
45 |
0.986
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.986
|
Human Mouse |
|
axonogenesis
|
GO:0007409 |
31 |
0.985
|
Fly |
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.984
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.984
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.984
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.983
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.982
|
Human |
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.981
|
Human |
|
endosomal transport
|
GO:0016197 |
129 |
0.981
|
Human |
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.979
|
|
|
memory
|
GO:0007613 |
3 |
0.979
|
Fly |
|
epithelium migration
|
GO:0090132 |
119 |
0.979
|
Human |
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.978
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.978
|
Human |
|
axon development
|
GO:0061564 |
34 |
0.978
|
Fly |
|
response to peptide
|
GO:1901652 |
65 |
0.978
|
Rat |
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.976
|
Rat |
|
peptidyl tyrosine autophosphorylation
|
GO:0038083 |
5 |
0.976
|
Human Worm |
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.976
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.975
|
Human |
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.974
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.974
|
Human |
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.974
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.974
|
Human Rat |
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.973
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.973
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.973
|
Human Mouse |
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.972
|
Human |
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.971
|
Human |
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.969
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.968
|
Human |
|
protein localization to membrane
|
GO:0072657 |
160 |
0.968
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.967
|
Fly |
|
membrane organization
|
GO:0061024 |
292 |
0.967
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.966
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.966
|
Human |
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.965
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.964
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.963
|
Human |
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.962
|
Mouse Fly |
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.962
|
Human Fly |
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.961
|
Fly |
|
regulation of early endosome to late endosome transport
|
GO:2000641 |
6 |
0.961
|
Human |
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.960
|
Human |
|
system process
|
GO:0003008 |
349 |
0.960
|
Mouse Fly |
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.960
|
Human |
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.959
|
Human Fly |
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.958
|
Human |
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.956
|
Human Mouse |
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.955
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.954
|
Human |
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.954
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.952
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.950
|
Fly |
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.947
|
Human Rat |
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.947
|
Human |
|
endomembrane system organization
|
GO:0010256 |
196 |
0.946
|
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
2 |
0.946
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.945
|
Human |
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.945
|
Human |
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.945
|
Human Fly |
|
gliogenesis
|
GO:0042063 |
21 |
0.945
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.941
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.941
|
Human Zebrafish Fly |
|
biological adhesion
|
GO:0022610 |
331 |
0.940
|
Human Fly |
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.940
|
Human Fly |
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.939
|
Human Mouse Rat |
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.938
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.936
|
Human |
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.932
|
Human |
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.932
|
Human |
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.930
|
Human |
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.928
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.926
|
Human Mouse |
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.925
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.924
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.923
|
Mouse |
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.922
|
Human |
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.919
|
Human |
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.916
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.916
|
Human |
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.915
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.915
|
Human Fly |
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.913
|
Human Mouse Fly |
|
endoderm development
|
GO:0007492 |
33 |
0.912
|
Worm |
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.912
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.912
|
Worm |
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.912
|
Human Zebrafish Fly |
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.912
|
Human |
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.910
|
Human |
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.907
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.903
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.900
|
Human |
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.899
|
Human |
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.898
|
Fly |
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.898
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.897
|
Human |
|
regulation of wound healing
|
GO:0061041 |
56 |
0.896
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.896
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.896
|
Fly |
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.891
|
Worm |
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.890
|
Worm |
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.889
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.888
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.887
|
Human |
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.887
|
|
|
neuron development
|
GO:0048666 |
113 |
0.882
|
Human Mouse Fly |
|
cellular homeostasis
|
GO:0019725 |
196 |
0.881
|
Human |
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.879
|
Human |
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.878
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.873
|
Human |
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.870
|
Human |
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.869
|
Human |
|
response to retinoic acid
|
GO:0032526 |
33 |
0.869
|
Human |
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.867
|
Human |
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.866
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.863
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.863
|
Human |
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.861
|
Human Fly |
|
anoikis
|
GO:0043276 |
22 |
0.854
|
Human |
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.847
|
|
|
epithelial cell cell adhesion
|
GO:0090136 |
7 |
0.846
|
Fly |
|
growth
|
GO:0040007 |
202 |
0.846
|
Zebrafish Fly |
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.845
|
|
|
regulation of cgmp mediated signaling
|
GO:0010752 |
1 |
0.844
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.843
|
Fly |
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.843
|
Human |
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.838
|
|
|
amide transport
|
GO:0042886 |
76 |
0.838
|
Human |
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.833
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.832
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.831
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.829
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.828
|
Human |
|
cell chemotaxis
|
GO:0060326 |
112 |
0.828
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.826
|
Human |
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.824
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.820
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
10 |
0.818
|
Human |
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.816
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.813
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.806
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.806
|
Human Fly |
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.802
|
Human |
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.799
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.797
|
Worm Fly |
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.793
|
Human |
|
plasma membrane organization
|
GO:0007009 |
115 |
0.793
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.790
|
Human Fly |
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.789
|
Human |
|
protein maturation
|
GO:0051604 |
233 |
0.785
|
Human |
|
response to acid chemical
|
GO:0001101 |
66 |
0.782
|
Human |
|
response to oxidative stress
|
GO:0006979 |
121 |
0.780
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.778
|
Human |
|
innate immune response
|
GO:0045087 |
178 |
0.772
|
Human |
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.762
|
Human |
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.761
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.760
|
Human |
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.760
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.759
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.758
|
Human Mouse |
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.757
|
Human |
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.755
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.752
|
|
|
associative learning
|
GO:0008306 |
1 |
0.748
|
Fly |
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.746
|
Human Mouse Rat Worm |
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.746
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.736
|
|
|
response to drug
|
GO:0042493 |
81 |
0.733
|
Human Rat |
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.730
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.728
|
Human |
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.728
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.726
|
Human |
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.725
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.725
|
Human |
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.720
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.717
|
Human |
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.716
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.712
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.711
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.704
|
Fly |
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.701
|
Human |
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.700
|
Fly |
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.698
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.696
|
Human Mouse |
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.691
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.690
|
Human Mouse Rat |
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.686
|
Human |
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.668
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.666
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.663
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.659
|
Human |
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.657
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.655
|
Human Fly |
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.648
|
Human Fly |
|
taxis
|
GO:0042330 |
157 |
0.645
|
Fly |
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.642
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.638
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.638
|
Human Rat |
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.638
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.638
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.632
|
Human |
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.628
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.625
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.625
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.624
|
Human Fly |
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.621
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.620
|
Human |
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.616
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.610
|
Human |
|
lipid metabolic process
|
GO:0006629 |
381 |
0.609
|
Human |
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.609
|
Human |
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.602
|
|
|
wound healing
|
GO:0042060 |
115 |
0.602
|
Zebrafish |
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.595
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.591
|
Human Rat |
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.589
|
Human |
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.581
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.579
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.576
|
Human |
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.575
|
Mouse Fly |
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.574
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.566
|
Human |
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.565
|
Mouse |
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.565
|
Human |
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.565
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.564
|
|
|
immune system development
|
GO:0002520 |
195 |
0.564
|
Human |
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.554
|
Human |
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.553
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.552
|
Mouse Fly |
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.552
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.551
|
Human |
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.546
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.546
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.540
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.539
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.536
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.536
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.534
|
Fly |
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.534
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.533
|
Human |
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.533
|
Zebrafish |
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.532
|
Human Rat |
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.525
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.518
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.516
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.514
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.513
|
Mouse |
|
muscle cell development
|
GO:0055001 |
29 |
0.511
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.506
|
Human |
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.506
|
Human |
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.504
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.501
|
Human |
|
adherens junction assembly
|
GO:0034333 |
34 |
0.500
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.498
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.496
|
Fly |
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.484
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.476
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.470
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.470
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.469
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.468
|
Human |
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.464
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.464
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.461
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.457
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.455
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.454
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.453
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.453
|
Worm |
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.451
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.451
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.450
|
Human Mouse |
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.448
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.445
|
Human |
|
regulation of mrna catabolic process
|
GO:0061013 |
13 |
0.444
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.441
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.440
|
Human |
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.440
|
Human |
|
positive regulation of insulin secretion
|
GO:0032024 |
10 |
0.439
|
Human |
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.434
|
Fly |
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.430
|
Human Mouse |
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.428
|
Worm |
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.428
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.425
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.420
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.419
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.417
|
Human |
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.417
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
13 |
0.416
|
Human |
|
central nervous system development
|
GO:0007417 |
123 |
0.414
|
Mouse Fly |
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.410
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.406
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.404
|
|
|
mitochondrial depolarization
|
GO:0051882 |
6 |
0.402
|
Human |
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.397
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.397
|
Human |
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.396
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.393
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.392
|
Human |
|
chemical homeostasis
|
GO:0048878 |
306 |
0.391
|
Human |
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.390
|
Human Rat |
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.390
|
Human |
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.389
|
Human |
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.388
|
|
|
cellular response to fatty acid
|
GO:0071398 |
8 |
0.388
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.388
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.386
|
Human |
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.385
|
Rat |
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.385
|
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.383
|
Fly |
|
cellular response to peptide
|
GO:1901653 |
59 |
0.378
|
Rat |
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.374
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.372
|
Human |
|
zymogen activation
|
GO:0031638 |
70 |
0.369
|
Human |
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.366
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.364
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.363
|
Worm |
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.363
|
Human |
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.362
|
|
|
macrophage chemotaxis
|
GO:0048246 |
10 |
0.361
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
13 |
0.360
|
Human |
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.359
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.357
|
Human |
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.354
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.354
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.354
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
15 |
0.354
|
Human |
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
9 |
0.352
|
|
|
clathrin mediated endocytosis
|
GO:0072583 |
8 |
0.351
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.350
|
|
|
translation
|
GO:0006412 |
132 |
0.350
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.348
|
Human |
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.348
|
Human |
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.346
|
Human Rat |
|
muscle organ development
|
GO:0007517 |
56 |
0.345
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.340
|
Fly |
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.337
|
Human |
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.335
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.334
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.332
|
Human |
|
cell activation
|
GO:0001775 |
213 |
0.332
|
Human Mouse |
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.331
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.331
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.330
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.329
|
Human Rat |
|
somatic stem cell division
|
GO:0048103 |
1 |
0.329
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.329
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.328
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.322
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.322
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.317
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.315
|
Human Rat |
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.313
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.313
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.313
|
Fly |
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.312
|
Mouse |
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.310
|
Human |
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.310
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.309
|
Human |
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.305
|
Mouse |
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.302
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.299
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.297
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.295
|
Human |
|
spindle organization
|
GO:0007051 |
53 |
0.295
|
Worm |
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.292
|
Human |
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.291
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.289
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.288
|
|
|
transcytosis
|
GO:0045056 |
1 |
0.283
|
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.282
|
|
|
platelet derived growth factor receptor beta signaling pathway
|
GO:0035791 |
4 |
0.281
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.281
|
Human |
|
defense response
|
GO:0006952 |
315 |
0.279
|
Human |
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.277
|
Worm |
|
secretion by cell
|
GO:0032940 |
226 |
0.276
|
Human |
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.276
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.276
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.274
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.273
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.272
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.272
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.271
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.271
|
Human Rat |
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.270
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.269
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.267
|
Worm |
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.265
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.263
|
Human |
|
platelet activation
|
GO:0030168 |
44 |
0.259
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.258
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
6 |
0.257
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.256
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.256
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.255
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.254
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.253
|
Worm |
|
microtubule based process
|
GO:0007017 |
210 |
0.253
|
Worm |
|
regeneration
|
GO:0031099 |
4 |
0.253
|
Zebrafish |
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.252
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.252
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.250
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
15 |
0.248
|
Human |