|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.996
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.992
|
Human Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.990
|
|
|
|
cortisol secretion
|
GO:0043400 |
4 |
0.985
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.982
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.979
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.978
|
Mouse |
|
|
regulation of glucocorticoid secretion
|
GO:2000849 |
4 |
0.971
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.965
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.956
|
Mouse |
|
|
glucocorticoid secretion
|
GO:0035933 |
4 |
0.942
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.935
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.934
|
Mouse |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.934
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.929
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.914
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.910
|
Human Mouse |
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.898
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.885
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.878
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.869
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.828
|
Mouse |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.812
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.809
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.808
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.787
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.784
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.780
|
|
|
|
negative regulation of hydrogen peroxide mediated programmed cell death
|
GO:1901299 |
3 |
0.776
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.765
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.761
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.751
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.740
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.696
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.690
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.689
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.685
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.675
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.653
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.645
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.643
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.640
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.634
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.613
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.609
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.603
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.597
|
Mouse |
|
|
associative learning
|
GO:0008306 |
1 |
0.594
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.591
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.583
|
Mouse |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.578
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.576
|
Mouse |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.572
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.560
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.557
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.552
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.544
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.535
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.533
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.530
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.529
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.528
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.518
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.513
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.508
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.496
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.489
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.488
|
Mouse |
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.482
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.476
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.475
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.473
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.463
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.459
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.458
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.457
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.451
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.450
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.448
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.446
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.439
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.439
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.436
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.432
|
Fly |
|
|
male genitalia development
|
GO:0030539 |
1 |
0.426
|
|
|
|
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling
|
GO:0060665 |
1 |
0.416
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.413
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.410
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.408
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.400
|
Mouse |
|
|
positive regulation of glucose import in response to insulin stimulus
|
GO:2001275 |
3 |
0.399
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.395
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.393
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.393
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.387
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.377
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.375
|
|
|
|
regulation of hydrogen peroxide mediated programmed cell death
|
GO:1901298 |
4 |
0.372
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.369
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.366
|
|
|
|
negative regulation of receptor activity
|
GO:2000272 |
15 |
0.363
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.360
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.348
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.338
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.337
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.333
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.332
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.331
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.328
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.326
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.318
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.314
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.312
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.312
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.310
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.308
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.307
|
Fly |
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.302
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.301
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.296
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.296
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.294
|
|
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.291
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.290
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.288
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.284
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.284
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.282
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.282
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.279
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.277
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.277
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.277
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.277
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.275
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.274
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.273
|
|
|
|
cell cell junction maintenance
|
GO:0045217 |
4 |
0.273
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.270
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.270
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.268
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.266
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.265
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.264
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.263
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.262
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.260
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.259
|
|
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.256
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.255
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.252
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.251
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.249
|
|
|
|
semicircular canal morphogenesis
|
GO:0048752 |
1 |
0.247
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.247
|
Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.246
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.241
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.241
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.240
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.240
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.239
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.236
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.233
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.231
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.230
|
Fly |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.226
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.224
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.223
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.223
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.223
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.221
|
Mouse |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.220
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.220
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.218
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.217
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.217
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.216
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.215
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.214
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.212
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.212
|
|
|
|
programmed cell death in response to reactive oxygen species
|
GO:0097468 |
4 |
0.211
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.210
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.210
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.209
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.209
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.207
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.206
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.204
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.204
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.203
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.202
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.202
|
Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.201
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.201
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.200
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.199
|
|
|
|
regulation of glucose import in response to insulin stimulus
|
GO:2001273 |
4 |
0.198
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.198
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.198
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.197
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.194
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.193
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.193
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.193
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.191
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.190
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.190
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.188
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.186
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.186
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.186
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.185
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.184
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.184
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.183
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.183
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.181
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.181
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.181
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.180
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.180
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.180
|
|
|
|
hydrogen peroxide mediated programmed cell death
|
GO:0010421 |
4 |
0.178
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.178
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.177
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.177
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.176
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.175
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.175
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.174
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.172
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.171
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.169
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.169
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.168
|
|
|
|
negative regulation of dendritic cell apoptotic process
|
GO:2000669 |
3 |
0.167
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.166
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.165
|
Mouse |
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.163
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.162
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.162
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.162
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.160
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.158
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.157
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.157
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.157
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.156
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.156
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.156
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.156
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.155
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.155
|
Mouse |
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.155
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.155
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.155
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.153
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.151
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.150
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.150
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.150
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.149
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.148
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.148
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.148
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.148
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.148
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.147
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.147
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.147
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.146
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.146
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.145
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.145
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.144
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.143
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.143
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.142
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.141
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.140
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.139
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.139
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.135
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.135
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.134
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.132
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.132
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.132
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.130
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.129
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.129
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.129
|
|
|
|
growth hormone secretion
|
GO:0030252 |
4 |
0.129
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.128
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.128
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.128
|
Mouse |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.127
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.126
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.126
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.126
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.125
|
|
|
|
memory
|
GO:0007613 |
3 |
0.124
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
6 |
0.123
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.122
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.121
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.121
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.120
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.119
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.118
|
|
|
|
glucose import in response to insulin stimulus
|
GO:0044381 |
4 |
0.118
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.118
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.117
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.117
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.115
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.115
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.115
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.114
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.113
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.113
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.112
|
|
|
|
negative regulation of hydrogen peroxide induced cell death
|
GO:1903206 |
9 |
0.112
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.112
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.112
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.110
|
|
|
|
cell migration involved in kidney development
|
GO:0035787 |
2 |
0.110
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.109
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.108
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.108
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.108
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.107
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.107
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.107
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.107
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.106
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.106
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.105
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.105
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.105
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.105
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.104
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.104
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.103
|
Mouse |
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.103
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.102
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.101
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.100
|
Human |
|
|
chemokine production
|
GO:0032602 |
32 |
0.100
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.099
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.099
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.098
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.098
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.096
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.096
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.096
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.096
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.095
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.095
|
Mouse |
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.095
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.095
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.095
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.093
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.093
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.092
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.092
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
23 |
0.091
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.091
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.090
|
|
|
|
system process
|
GO:0003008 |
349 |
0.090
|
|
|
|
mesenchymal stem cell differentiation
|
GO:0072497 |
8 |
0.089
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.089
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.089
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.088
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.088
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.088
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.087
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.087
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.086
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.086
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.084
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.084
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.084
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.083
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.083
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.083
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.082
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.082
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.082
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.082
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.082
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.082
|
|
|
|
cell death in response to hydrogen peroxide
|
GO:0036474 |
10 |
0.081
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.081
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.081
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.080
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.080
|
Fly |
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.080
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.079
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.079
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.078
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.077
|
Fly |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.077
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.077
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.076
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.076
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.076
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.075
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.074
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.074
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.074
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.074
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.074
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.074
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.073
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.072
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.072
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.072
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.072
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.072
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.072
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.072
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.072
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.071
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
4 |
0.071
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.071
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.070
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.070
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.069
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.069
|
|
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
2 |
0.069
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.069
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.068
|
Mouse |
|
|
kit signaling pathway
|
GO:0038109 |
1 |
0.068
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.068
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.067
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.067
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.067
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.067
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.067
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.067
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.067
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.066
|
Mouse |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.066
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.066
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.066
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.066
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.065
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.065
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.065
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.065
|
Fly |
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.065
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.065
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.064
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.064
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.064
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.064
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.064
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.063
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.063
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.062
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.062
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.062
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.062
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.061
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.061
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.061
|
|
|
|
gastro intestinal system smooth muscle contraction
|
GO:0014831 |
2 |
0.061
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.061
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.060
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.060
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.060
|
Mouse |
|
|
positive regulation of natural killer cell differentiation
|
GO:0032825 |
2 |
0.060
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.060
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.060
|
|
|
|
growth
|
GO:0040007 |
202 |
0.059
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.059
|
|
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.058
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.058
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.058
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.058
|
|
|
|
positive regulation of glucose transport
|
GO:0010828 |
17 |
0.058
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.058
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.057
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.057
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.057
|
|
