|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.784
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.604
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.566
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.486
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.447
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.438
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.435
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.421
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.409
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.396
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.374
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.371
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.371
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.357
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.346
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.339
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.331
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.322
|
|
|
|
glucocorticoid secretion
|
GO:0035933 |
4 |
0.318
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.305
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.303
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.301
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.294
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.289
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.283
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.283
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.261
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.256
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.251
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.251
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.246
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.245
|
Fly |
|
|
cortisol secretion
|
GO:0043400 |
4 |
0.241
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.240
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.236
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.230
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.230
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.228
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.226
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.216
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.214
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.203
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.203
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.202
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.200
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.196
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.195
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.194
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.190
|
Fly |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.190
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.186
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.185
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.184
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.183
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.181
|
Fly |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.175
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.175
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.175
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.170
|
|
|
|
regulation of glucocorticoid secretion
|
GO:2000849 |
4 |
0.167
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.166
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.164
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.159
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.152
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.152
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.149
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.149
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.148
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.147
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.144
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.142
|
Mouse |
|
|
regeneration
|
GO:0031099 |
4 |
0.141
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.140
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.137
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.136
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.134
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.134
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.133
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.132
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.131
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.130
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.129
|
Mouse |
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.128
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.127
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.126
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.126
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.125
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.125
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.124
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.123
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.122
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.122
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.119
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.115
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.115
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.114
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.114
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.113
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.113
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.113
|
Mouse |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.112
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.112
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.112
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.111
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.109
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.109
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.105
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.105
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.103
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.102
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.102
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.102
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.101
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.100
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.097
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.097
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.095
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.094
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.092
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.092
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.092
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.092
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.092
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.091
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.091
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.091
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.090
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.090
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.090
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.090
|
|
|
|
av node cell to bundle of his cell communication
|
GO:0086067 |
4 |
0.089
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.089
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.089
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.088
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.087
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.087
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.087
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.086
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.085
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.085
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.085
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.085
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.084
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.082
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.082
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.082
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.081
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.080
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.080
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.080
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.080
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.080
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.077
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.076
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.076
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.076
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.075
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.073
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.072
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.072
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.071
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.071
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.071
|
Fly |
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.071
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.069
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.069
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.068
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.068
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.068
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.068
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.068
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.068
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.067
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.066
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.066
|
|
|
|
translation
|
GO:0006412 |
132 |
0.066
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.066
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.065
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.065
|
|
|
|
regulation of cardiac muscle cell apoptotic process
|
GO:0010665 |
3 |
0.065
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.065
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.064
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.063
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.063
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.063
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.063
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.063
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.062
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.062
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.062
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.062
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.062
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.062
|
Mouse |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.061
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.061
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.061
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.060
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.060
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.060
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.060
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.060
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.060
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.059
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.058
|
Fly |
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.058
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.058
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.058
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.057
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.057
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.056
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.056
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.056
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.056
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.056
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.056
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.056
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.055
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.055
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.055
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.054
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.054
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.054
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.054
|
Mouse |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.054
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.054
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.053
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.053
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.053
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.053
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.053
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.053
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.053
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
31 |
0.052
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.052
|
Fly |
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.051
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.051
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.051
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.050
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.050
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.050
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.049
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.049
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.049
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.049
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.049
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.049
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.049
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.049
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.048
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.048
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.048
|
|
|
|
positive regulation of glucose import in response to insulin stimulus
|
GO:2001275 |
3 |
0.048
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.048
|
|
|
|
nerve growth factor signaling pathway
|
GO:0038180 |
4 |
0.048
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.048
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.047
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.047
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.047
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.047
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.047
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.047
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.047
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.046
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.046
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.046
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.046
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.045
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.045
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.045
|
Mouse |
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.045
|
|
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.045
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.045
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.044
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.044
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.044
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.044
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.044
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.044
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.044
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.044
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.044
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.043
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.043
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.043
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.043
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.043
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.043
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.043
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.043
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.042
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.042
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.042
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.042
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.042
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.041
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.041
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.041
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.041
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.041
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.041
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.041
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.041
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.040
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.040
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.040
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.040
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.040
|
Mouse |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.040
|
|
|
|
cell cell junction maintenance
|
GO:0045217 |
4 |
0.040
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.040
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.040
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.040
|
Mouse |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.040
|
|
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.039
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.039
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.039
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.039
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.039
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.039
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.039
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.039
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.039
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.038
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.038
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.038
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.038
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.038
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.038
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.037
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.037
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.037
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.037
|
|
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
0.037
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.037
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.036
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.036
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.036
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.035
|
|
|
|
response to testosterone
|
GO:0033574 |
1 |
0.035
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.035
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.035
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.035
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.035
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.035
|
Mouse |
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
6 |
0.035
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.035
|
Mouse |
|
|
growth hormone secretion
|
GO:0030252 |
4 |
0.034
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.034
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.034
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.034
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.034
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.034
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.034
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.034
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.034
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.034
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.034
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.033
|
|
|
|
gastro intestinal system smooth muscle contraction
|
GO:0014831 |
2 |
0.033
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.033
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.033
|
Mouse Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.033
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.033
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.033
|
|
|
|
growth
|
GO:0040007 |
202 |
0.033
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.033
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.033
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.032
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.032
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.032
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.032
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.032
|
|
|
|
regulation of cortisol secretion
|
GO:0051462 |
4 |
0.032
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.032
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.032
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.032
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.032
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.032
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.032
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.032
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.032
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.031
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.031
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.031
|
|
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.031
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.031
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.030
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.030
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.030
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.030
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.030
|
|
|
|
positive regulation of toll like receptor signaling pathway
|
GO:0034123 |
10 |
0.030
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.030
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.030
|
|
|
|
glucose import in response to insulin stimulus
|
GO:0044381 |
4 |
0.030
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.030
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.030
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.029
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.029
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.029
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.029
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.029
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.029
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
24 |
0.029
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.029
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.029
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.029
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.029
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.029
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.028
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.028
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.028
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.028
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.028
|
|
|
|
system process
|
GO:0003008 |
349 |
0.028
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.028
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.028
|
|
|
|
surfactant homeostasis
|
GO:0043129 |
3 |
0.028
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.028
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.028
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.028
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
22 |
0.028
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.027
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
Mouse |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.027
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.027
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.027
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.027
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.027
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
1 |
0.027
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.027
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.027
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.027
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.027
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.027
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.027
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.027
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.027
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.026
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.026
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.026
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.026
|
|
|
|
aging
|
GO:0007568 |
66 |
0.026
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.026
|
|
|
|
schwann cell development
|
GO:0014044 |
1 |
0.026
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.026
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.026
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.026
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.026
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.025
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.025
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.025
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.025
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.025
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.025
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.025
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.025
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.025
|
Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.025
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.025
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.025
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.025
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.025
|
|
|
|
regulation of glucose import in response to insulin stimulus
|
GO:2001273 |
4 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.025
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.024
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.024
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.024
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.024
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.024
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.024
|
|
