Homo sapiens

50 known processes

GARS

glycyl-tRNA synthetase

(Aliases: DSMAV,GlyRS,SMAD1,HMN5,CMT2D)

GARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna aminoacylation for protein translation GO:0006418 8 1.000
Yeast
amino acid activation GO:0043038 12 1.000
Yeast
trna aminoacylation GO:0043039 12 1.000
Yeast
cellular amino acid metabolic process GO:0006520 116 0.998
Yeast
translation GO:0006412 132 0.991
Yeast
ncrna metabolic process GO:0034660 108 0.857
Yeast
alpha amino acid metabolic process GO:1901605 72 0.843
post embryonic development GO:0009791 2 0.816
Worm
one carbon metabolic process GO:0006730 1 0.710
serine family amino acid metabolic process GO:0009069 12 0.659
trna metabolic process GO:0006399 35 0.631
Yeast
regulation of translation GO:0006417 89 0.620
coenzyme metabolic process GO:0006732 65 0.591
alpha amino acid catabolic process GO:1901606 26 0.544
response to organic cyclic compound GO:0014070 204 0.506
sulfur amino acid transport GO:0000101 2 0.501
response to amino acid GO:0043200 14 0.477
cellular amino acid biosynthetic process GO:0008652 30 0.433
response to organonitrogen compound GO:0010243 156 0.397
dicarboxylic acid metabolic process GO:0043648 29 0.379
organic acid biosynthetic process GO:0016053 97 0.329
l serine metabolic process GO:0006563 5 0.317
alpha amino acid biosynthetic process GO:1901607 23 0.316
serine family amino acid catabolic process GO:0009071 5 0.313
small molecule biosynthetic process GO:0044283 157 0.285
organic anion transport GO:0015711 103 0.278
cellular response to endogenous stimulus GO:0071495 336 0.255
regulation of translational elongation GO:0006448 2 0.255
proline transport GO:0015824 4 0.253
response to nitrogen compound GO:1901698 184 0.248
aspartate family amino acid biosynthetic process GO:0009067 6 0.247
carboxylic acid transport GO:0046942 63 0.246
organonitrogen compound biosynthetic process GO:1901566 200 0.219
negative regulation of apoptotic process GO:0043066 316 0.213
embryo development GO:0009790 123 0.207
Worm
oogenesis GO:0048477 2 0.194
carbohydrate metabolic process GO:0005975 207 0.182
cellular amino acid catabolic process GO:0009063 31 0.171
rna processing GO:0006396 255 0.169
circulatory system development GO:0072359 262 0.165
chemical homeostasis GO:0048878 306 0.165
response to peptide GO:1901652 65 0.150
multicellular organismal aging GO:0010259 3 0.149
hindbrain development GO:0030902 3 0.145
protein folding GO:0006457 38 0.141
l serine catabolic process GO:0006565 3 0.131
alanine transport GO:0032328 3 0.123
organic acid transport GO:0015849 65 0.123
determination of adult lifespan GO:0008340 2 0.111
female gamete generation GO:0007292 2 0.108
nervous system development GO:0007399 293 0.106
chloride transmembrane transport GO:1902476 38 0.095
posttranscriptional regulation of gene expression GO:0010608 213 0.095
angiogenesis GO:0001525 147 0.084
negative regulation of cell death GO:0060548 345 0.082
patterning of blood vessels GO:0001569 2 0.081
positive regulation of mitotic cell cycle GO:0045931 60 0.081
embryo development ending in birth or egg hatching GO:0009792 34 0.080
Worm
purine nucleobase biosynthetic process GO:0009113 3 0.072
cellular carbohydrate biosynthetic process GO:0034637 21 0.070
response to hormone GO:0009725 175 0.067
leukocyte mediated cytotoxicity GO:0001909 27 0.064
metencephalon development GO:0022037 2 0.063
epithelium development GO:0060429 227 0.062
response to oxygen containing compound GO:1901700 369 0.059
amide biosynthetic process GO:0043604 15 0.059
response to sucrose GO:0009744 1 0.058
dicarboxylic acid catabolic process GO:0043649 9 0.056
negative regulation of programmed cell death GO:0043069 321 0.055
regulation of anatomical structure morphogenesis GO:0022603 286 0.055
oxaloacetate metabolic process GO:0006107 1 0.054
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.052
reproductive process GO:0022414 106 0.052
pigment biosynthetic process GO:0046148 10 0.051
cellular response to cytokine stimulus GO:0071345 181 0.049
cellular response to external stimulus GO:0071496 111 0.049
response to mechanical stimulus GO:0009612 51 0.048
response to abiotic stimulus GO:0009628 336 0.048
innate immune response GO:0045087 178 0.048
anion transport GO:0006820 161 0.048
regulation of cell cycle GO:0051726 393 0.045
blood vessel development GO:0001568 172 0.045
cytoplasmic translational initiation GO:0002183 6 0.044
carboxylic acid biosynthetic process GO:0046394 97 0.043
response to peptide hormone GO:0043434 61 0.043
cellular response to glucose starvation GO:0042149 8 0.043
organic cation transport GO:0015695 13 0.042
nucleobase biosynthetic process GO:0046112 4 0.042
cellular amide metabolic process GO:0043603 69 0.042
arginine transport GO:0015809 2 0.042
liver development GO:0001889 9 0.042
regulation of mitotic cell cycle GO:0007346 189 0.041
cellular response to hormone stimulus GO:0032870 125 0.040
ires dependent translational initiation GO:0002192 4 0.040
regulation of angiogenesis GO:0045765 92 0.040
hair cycle GO:0042633 28 0.038
lung cell differentiation GO:0060479 1 0.038
l alanine transport GO:0015808 3 0.036
eye photoreceptor cell differentiation GO:0001754 2 0.035
positive regulation of cell cycle GO:0045787 140 0.033
cellular protein complex assembly GO:0043623 188 0.032
regulation of cell development GO:0060284 161 0.032
maintenance of location GO:0051235 112 0.032
positive regulation of interferon gamma production GO:0032729 26 0.031
organic hydroxy compound metabolic process GO:1901615 147 0.031
cation transport GO:0006812 331 0.031
cellular response to starvation GO:0009267 58 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
photoreceptor cell differentiation GO:0046530 2 0.031
cellular response to nutrient levels GO:0031669 69 0.030
reproduction GO:0000003 63 0.029
Worm
neuromuscular process GO:0050905 15 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.028
oocyte development GO:0048599 1 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
vasculature development GO:0001944 181 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
ncrna processing GO:0034470 83 0.028
transmembrane transport GO:0055085 399 0.028
response to extracellular stimulus GO:0009991 85 0.027
regulation of neuron death GO:1901214 56 0.027
hemopoiesis GO:0030097 180 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
fructose 6 phosphate metabolic process GO:0006002 3 0.026
response to radiation GO:0009314 151 0.026
positive regulation of cellular component organization GO:0051130 376 0.025
cellular amine metabolic process GO:0044106 41 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
cell development GO:0048468 328 0.025
response to topologically incorrect protein GO:0035966 29 0.025
intracellular mrna localization GO:0008298 1 0.024
cell type specific apoptotic process GO:0097285 125 0.023
immune response GO:0006955 307 0.023
trna transport GO:0051031 1 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
memory GO:0007613 3 0.022
negative regulation of cell migration GO:0030336 102 0.022
central nervous system development GO:0007417 123 0.022
cytokine biosynthetic process GO:0042089 37 0.022
protein homooligomerization GO:0051260 100 0.022
response to hypoxia GO:0001666 96 0.021
purine nucleobase metabolic process GO:0006144 5 0.021
positive regulation of catabolic process GO:0009896 310 0.020
cation transmembrane transport GO:0098655 238 0.020
protein tetramerization GO:0051262 47 0.020
positive regulation of protein polymerization GO:0032273 45 0.020
negative regulation of hydrolase activity GO:0051346 182 0.019
dna repair GO:0006281 198 0.019
blastoderm segmentation GO:0007350 2 0.019
cytoplasmic transport GO:0016482 379 0.019
protein targeting to nucleus GO:0044744 104 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
endoplasmic reticulum organization GO:0007029 20 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
cell activation GO:0001775 213 0.018
pigment metabolic process GO:0042440 16 0.018
response to starvation GO:0042594 59 0.018
nitrogen compound transport GO:0071705 191 0.018
oocyte differentiation GO:0009994 2 0.018
er nucleus signaling pathway GO:0006984 23 0.017
dephosphorylation GO:0016311 209 0.017
regeneration GO:0031099 4 0.017
regulation of dna repair GO:0006282 47 0.017
head development GO:0060322 108 0.017
vesicle mediated transport GO:0016192 371 0.017
Worm
nadh metabolic process GO:0006734 1 0.017
protein oligomerization GO:0051259 173 0.017
osteoblast differentiation GO:0001649 92 0.017
cellular protein catabolic process GO:0044257 261 0.017
positive regulation of protein catabolic process GO:0045732 75 0.017
leukocyte mediated immunity GO:0002443 59 0.017
response to gonadotropin GO:0034698 5 0.016
aspartate family amino acid catabolic process GO:0009068 5 0.016
skin development GO:0043588 76 0.016
hepaticobiliary system development GO:0061008 10 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
blood vessel morphogenesis GO:0048514 162 0.016
multicellular organismal reproductive process GO:0048609 40 0.016
hair cycle process GO:0022405 12 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
protein catabolic process GO:0030163 325 0.016
gland development GO:0048732 48 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to endoplasmic reticulum stress GO:0034976 49 0.015
receptor mediated endocytosis GO:0006898 84 0.015
Worm
cellular response to nitrogen compound GO:1901699 144 0.015
amine metabolic process GO:0009308 44 0.015
cerebellum development GO:0021549 2 0.015
ossification GO:0001503 121 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
neurogenesis GO:0022008 169 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
cell division GO:0051301 168 0.015
response to hydrogen peroxide GO:0042542 40 0.015
cellular modified amino acid metabolic process GO:0006575 64 0.014
nucleus localization GO:0051647 1 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of locomotion GO:0040012 329 0.014
cellular response to extracellular stimulus GO:0031668 72 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
positive regulation of transferase activity GO:0051347 227 0.014
cardiovascular system development GO:0072358 262 0.014
glycine metabolic process GO:0006544 4 0.014
response to insulin GO:0032868 45 0.013
negative regulation of neuron apoptotic process GO:0043524 23 0.013
regulation of cell differentiation GO:0045595 393 0.013
system process GO:0003008 349 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
cofactor metabolic process GO:0051186 87 0.013
single organism nuclear import GO:1902593 104 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
positive regulation of jak stat cascade GO:0046427 35 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
apoptotic signaling pathway GO:0097190 268 0.013
mitochondrion organization GO:0007005 156 0.013
Yeast
alcohol metabolic process GO:0006066 114 0.013
cellular response to peptide GO:1901653 59 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
amino acid transmembrane transport GO:0003333 20 0.013
neural crest cell development GO:0014032 3 0.013
cytokine metabolic process GO:0042107 38 0.012
response to virus GO:0009615 126 0.012
regulation of vasculature development GO:1901342 97 0.012
d aspartate transport GO:0070777 3 0.012
toxin transport GO:1901998 4 0.012
erythrocyte differentiation GO:0030218 28 0.012
single organism cellular localization GO:1902580 332 0.012
neurological system process GO:0050877 163 0.012
negative regulation of cell motility GO:2000146 104 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
negative regulation of developmental process GO:0051093 247 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
positive regulation of cell death GO:0010942 263 0.012
single organism cell adhesion GO:0098602 179 0.012
anterior posterior axis specification GO:0009948 2 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
metal ion transport GO:0030001 272 0.011
modified amino acid transport GO:0072337 11 0.011
cellular response to peptide hormone stimulus GO:0071375 56 0.011
tissue morphogenesis GO:0048729 96 0.011
cytokine production GO:0001816 247 0.011
locomotory behavior GO:0007626 1 0.011
tissue migration GO:0090130 119 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
regulation of actin filament based process GO:0032970 141 0.011
negative regulation of protein processing GO:0010955 142 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of transport GO:0051050 336 0.011
actin filament based movement GO:0030048 17 0.011
aging GO:0007568 66 0.011
regulation of interferon gamma biosynthetic process GO:0045072 8 0.011
segmentation GO:0035282 4 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
negative regulation of translation GO:0017148 37 0.011
sexual reproduction GO:0019953 37 0.011
regulation of actin filament length GO:0030832 56 0.011
rhythmic behavior GO:0007622 2 0.011
lung epithelial cell differentiation GO:0060487 1 0.011
interferon gamma production GO:0032609 39 0.011
negative regulation of phosphorylation GO:0042326 174 0.010
negative regulation of protein metabolic process GO:0051248 391 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
meiosis i GO:0007127 4 0.010
biological adhesion GO:0022610 331 0.010
molting cycle GO:0042303 28 0.010
positive regulation of protein complex assembly GO:0031334 86 0.010
protein import into nucleus GO:0006606 104 0.010

GARS disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.980
neuropathy DOID:870 52 0.980
neuromuscular disease DOID:440 38 0.960
charcot marie tooth disease DOID:10595 33 0.016
disease of metabolism DOID:0014667 295 0.014
amino acid metabolic disorder DOID:9252 50 0.014
inherited metabolic disorder DOID:655 242 0.014
sensory system disease DOID:0050155 203 0.011
gastrointestinal system cancer DOID:3119 52 0.011
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
organ system cancer DOID:0050686 164 0.011
central nervous system disease DOID:331 186 0.009
motor neuron disease DOID:231 27 0.002
neurodegenerative disease DOID:1289 102 0.002
charcot marie tooth disease type 2 DOID:0050539 15 0.001
motor neuritis DOID:683 5 0.001
distal hereditary motor neuropathy DOID:0050582 5 0.000