Homo sapiens

5 known processes

GCDH

glutaryl-CoA dehydrogenase

(Aliases: ACAD5,GCD)

GCDH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.752
small molecule catabolic process GO:0044282 92 0.453
carboxylic acid catabolic process GO:0046395 71 0.411
cellular amino acid catabolic process GO:0009063 31 0.381
oxidation reduction process GO:0055114 396 0.358
glutamine family amino acid metabolic process GO:0009064 17 0.203
organic acid catabolic process GO:0016054 71 0.195
mitochondrion organization GO:0007005 156 0.179
alpha amino acid catabolic process GO:1901606 26 0.174
single organism carbohydrate metabolic process GO:0044723 193 0.148
monocarboxylic acid metabolic process GO:0032787 185 0.116
response to abiotic stimulus GO:0009628 336 0.107
organic hydroxy compound metabolic process GO:1901615 147 0.091
protein oligomerization GO:0051259 173 0.075
coenzyme metabolic process GO:0006732 65 0.071
alpha amino acid metabolic process GO:1901605 72 0.071
amine metabolic process GO:0009308 44 0.069
cofactor metabolic process GO:0051186 87 0.066
fatty acid metabolic process GO:0006631 115 0.062
carbohydrate metabolic process GO:0005975 207 0.061
cellular ketone metabolic process GO:0042180 80 0.058
cellular macromolecule catabolic process GO:0044265 380 0.058
system process GO:0003008 349 0.055
response to oxygen containing compound GO:1901700 369 0.055
small molecule biosynthetic process GO:0044283 157 0.050
protein homooligomerization GO:0051260 100 0.049
protein catabolic process GO:0030163 325 0.049
regulation of cellular amino acid metabolic process GO:0006521 6 0.048
response to hypoxia GO:0001666 96 0.047
post embryonic development GO:0009791 2 0.046
response to lipid GO:0033993 206 0.044
cellular protein complex assembly GO:0043623 188 0.044
mitochondrial rna metabolic process GO:0000959 15 0.043
posttranscriptional regulation of gene expression GO:0010608 213 0.042
protein localization to mitochondrion GO:0070585 25 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
cellular lipid metabolic process GO:0044255 303 0.041
translation GO:0006412 132 0.040
positive regulation of hydrolase activity GO:0051345 331 0.038
secretion GO:0046903 254 0.038
organic acid biosynthetic process GO:0016053 97 0.038
steroid metabolic process GO:0008202 94 0.036
sulfate transmembrane transport GO:1902358 3 0.033
cellular response to dna damage stimulus GO:0006974 379 0.033
alcohol metabolic process GO:0006066 114 0.033
mitochondrial respiratory chain complex assembly GO:0033108 23 0.032
response to axon injury GO:0048678 1 0.032
response to organic cyclic compound GO:0014070 204 0.032
lipid biosynthetic process GO:0008610 177 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
regulation of oxidoreductase activity GO:0051341 43 0.030
regulation of apoptotic signaling pathway GO:2001233 175 0.029
cellular amine metabolic process GO:0044106 41 0.028
dicarboxylic acid metabolic process GO:0043648 29 0.028
branched chain amino acid catabolic process GO:0009083 4 0.028
regulation of proteolysis GO:0030162 293 0.027
positive regulation of cell death GO:0010942 263 0.027
organophosphate catabolic process GO:0046434 430 0.026
cellular response to oxidative stress GO:0034599 85 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
cellular amino acid biosynthetic process GO:0008652 30 0.026
protein processing GO:0016485 226 0.026
purine containing compound catabolic process GO:0072523 411 0.025
single organism cellular localization GO:1902580 332 0.025
response to organonitrogen compound GO:0010243 156 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
protein import GO:0017038 130 0.024
purine ribonucleotide biosynthetic process GO:0009152 79 0.024
response to hormone GO:0009725 175 0.024
positive regulation of programmed cell death GO:0043068 249 0.023
response to cytokine GO:0034097 232 0.023
lipid modification GO:0030258 84 0.023
response to nitrogen compound GO:1901698 184 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
secretion by cell GO:0032940 226 0.022
negative regulation of protein kinase activity GO:0006469 98 0.022
positive regulation of developmental process GO:0051094 314 0.022
oxidoreduction coenzyme metabolic process GO:0006733 19 0.022
regulation of transferase activity GO:0051338 355 0.022
response to wounding GO:0009611 168 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
response to oxidative stress GO:0006979 121 0.021
nucleotide biosynthetic process GO:0009165 109 0.021
lipid metabolic process GO:0006629 381 0.021
carboxylic acid transport GO:0046942 63 0.021
cellular response to cytokine stimulus GO:0071345 181 0.021
intracellular protein transport GO:0006886 270 0.020
dna repair GO:0006281 198 0.020
response to peptide GO:1901652 65 0.020
regulation of immune response GO:0050776 201 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
ncrna metabolic process GO:0034660 108 0.020
regulation of protein kinase activity GO:0045859 289 0.019
carboxylic acid biosynthetic process GO:0046394 97 0.019
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.019
regulation of peptidase activity GO:0052547 180 0.018
chemical homeostasis GO:0048878 306 0.018
negative regulation of cell death GO:0060548 345 0.018
mitochondrial transport GO:0006839 60 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
positive regulation of proteolysis GO:0045862 142 0.018
spermatid differentiation GO:0048515 4 0.018
response to oxygen levels GO:0070482 100 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
regulation of cell growth GO:0001558 135 0.017
regulation of kinase activity GO:0043549 314 0.017
ion transmembrane transport GO:0034220 338 0.017
regulation of protein processing GO:0070613 150 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
apoptotic signaling pathway GO:0097190 268 0.017
regulation of defense response GO:0031347 154 0.017
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
immune response GO:0006955 307 0.017
positive regulation of catabolic process GO:0009896 310 0.017
negative regulation of transferase activity GO:0051348 124 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
lipid catabolic process GO:0016042 84 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
protein homotetramerization GO:0051289 28 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
nucleotide catabolic process GO:0009166 408 0.016
protein localization to organelle GO:0033365 280 0.016
oogenesis GO:0048477 2 0.016
immune effector process GO:0002252 159 0.016
response to hyperoxia GO:0055093 4 0.016
protein maturation GO:0051604 233 0.016
defense response GO:0006952 315 0.016
mitochondrion distribution GO:0048311 3 0.015
female gamete generation GO:0007292 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
immune system development GO:0002520 195 0.015
regulation of hormone levels GO:0010817 125 0.015
alpha amino acid biosynthetic process GO:1901607 23 0.015
negative regulation of developmental process GO:0051093 247 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
amino acid activation GO:0043038 12 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
regulation of response to external stimulus GO:0032101 222 0.014
regulation of dna metabolic process GO:0051052 153 0.014
ion homeostasis GO:0050801 230 0.014
positive regulation of protein catabolic process GO:0045732 75 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
protein tetramerization GO:0051262 47 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
response to acid chemical GO:0001101 66 0.014
negative regulation of kinase activity GO:0033673 106 0.014
response to drug GO:0042493 81 0.013
response to metal ion GO:0010038 84 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
cytoplasmic transport GO:0016482 379 0.013
protein localization to membrane GO:0072657 160 0.013
regulation of multi organism process GO:0043900 157 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
regulation of growth GO:0040008 165 0.013
negative regulation of response to external stimulus GO:0032102 83 0.013
regulation of cellular response to stress GO:0080135 244 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
cell cell signaling GO:0007267 155 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
organelle assembly GO:0070925 176 0.012
organic acid transport GO:0015849 65 0.012
response to increased oxygen levels GO:0036296 4 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
covalent chromatin modification GO:0016569 254 0.012
ras protein signal transduction GO:0007265 73 0.012
regulation of protein catabolic process GO:0042176 155 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
regulation of blood coagulation GO:0030193 42 0.012
cellular response to nitrogen compound GO:1901699 144 0.011
hormone metabolic process GO:0042445 61 0.011
spermatid development GO:0007286 4 0.011
peptide transport GO:0015833 74 0.011
positive regulation of killing of cells of other organism GO:0051712 4 0.011
negative regulation of protein processing GO:0010955 142 0.011
response to decreased oxygen levels GO:0036293 96 0.011
cellular hormone metabolic process GO:0034754 41 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
dicarboxylic acid biosynthetic process GO:0043650 4 0.011
reproductive process GO:0022414 106 0.011
biological adhesion GO:0022610 331 0.011
regulation of cgmp biosynthetic process GO:0030826 4 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
cellular chemical homeostasis GO:0055082 180 0.011
locomotory behavior GO:0007626 1 0.010
regulation of peptide transport GO:0090087 62 0.010
regulation of protein maturation GO:1903317 150 0.010
neuron death GO:0070997 65 0.010
alcohol biosynthetic process GO:0046165 52 0.010
transmembrane transport GO:0055085 399 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
protein targeting GO:0006605 187 0.010

GCDH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.973
inherited metabolic disorder DOID:655 242 0.973
amino acid metabolic disorder DOID:9252 50 0.320
central nervous system disease DOID:331 186 0.140
neurodegenerative disease DOID:1289 102 0.140
nervous system disease DOID:863 431 0.140
hypertension DOID:10763 13 0.072
artery disease DOID:0050828 23 0.072
vascular disease DOID:178 25 0.072
essential hypertension DOID:10825 8 0.072
cardiovascular system disease DOID:1287 106 0.072
immune system disease DOID:2914 155 0.065
disease of mental health DOID:150 70 0.027
cognitive disorder DOID:1561 29 0.027
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
disease of cellular proliferation DOID:14566 174 0.021
cancer DOID:162 167 0.017
carbohydrate metabolic disorder DOID:2978 55 0.016
eye disease DOID:5614 149 0.014
organ system cancer DOID:0050686 164 0.014
organic acidemia DOID:0060159 14 0.012
dementia DOID:1307 19 0.011
alzheimer s disease DOID:10652 16 0.011
tauopathy DOID:680 16 0.011
musculoskeletal system disease DOID:17 223 0.010