Homo sapiens

153 known processes

GCH1

GTP cyclohydrolase 1

(Aliases: DYT14,HPABH4B,GTPCH1,GCH,GTP-CH-1,DYT5,DYT5a)

GCH1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleoside triphosphate metabolic process GO:0009141 422 0.523
nucleoside catabolic process GO:0009164 408 0.523
ribonucleoside triphosphate metabolic process GO:0009199 412 0.381
purine ribonucleoside metabolic process GO:0046128 437 0.327
nucleotide catabolic process GO:0009166 408 0.312
purine ribonucleoside catabolic process GO:0046130 398 0.312
purine nucleoside monophosphate catabolic process GO:0009128 158 0.311
purine ribonucleotide catabolic process GO:0009154 404 0.308
negative regulation of cell death GO:0060548 345 0.228
purine nucleoside catabolic process GO:0006152 398 0.228
ribonucleotide catabolic process GO:0009261 405 0.226
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.221
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.219
cellular amino acid metabolic process GO:0006520 116 0.206
purine containing compound catabolic process GO:0072523 411 0.202
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.199
ribonucleoside monophosphate catabolic process GO:0009158 158 0.196
response to cytokine GO:0034097 232 0.187
determination of adult lifespan GO:0008340 2 0.186
atp catabolic process GO:0006200 157 0.171
nucleoside triphosphate catabolic process GO:0009143 394 0.164
multicellular organismal aging GO:0010259 3 0.154
ribonucleoside triphosphate catabolic process GO:0009203 391 0.144
nucleoside phosphate catabolic process GO:1901292 412 0.141
immune effector process GO:0002252 159 0.134
nucleoside monophosphate catabolic process GO:0009125 159 0.134
nucleoside monophosphate metabolic process GO:0009123 191 0.130
ribonucleoside monophosphate metabolic process GO:0009161 187 0.128
purine nucleoside triphosphate catabolic process GO:0009146 392 0.125
response to abiotic stimulus GO:0009628 336 0.114
atp metabolic process GO:0046034 176 0.110
post embryonic development GO:0009791 2 0.106
negative regulation of apoptotic process GO:0043066 316 0.103
organophosphate catabolic process GO:0046434 430 0.100
glycosyl compound catabolic process GO:1901658 413 0.098
mitochondrion organization GO:0007005 156 0.097
cellular amine metabolic process GO:0044106 41 0.097
ribonucleoside catabolic process GO:0042454 406 0.093
carbohydrate derivative biosynthetic process GO:1901137 207 0.091
purine nucleoside triphosphate metabolic process GO:0009144 412 0.091
purine nucleotide catabolic process GO:0006195 405 0.086
nucleotide biosynthetic process GO:0009165 109 0.083
intrinsic apoptotic signaling pathway GO:0097193 127 0.083
negative regulation of protein metabolic process GO:0051248 391 0.083
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.082
regulation of transferase activity GO:0051338 355 0.081
cell type specific apoptotic process GO:0097285 125 0.080
immune response GO:0006955 307 0.079
cellular response to dna damage stimulus GO:0006974 379 0.077
cellular macromolecular complex assembly GO:0034622 324 0.076
cell projection organization GO:0030030 252 0.072
cofactor metabolic process GO:0051186 87 0.072
organonitrogen compound biosynthetic process GO:1901566 200 0.069
purine nucleoside monophosphate metabolic process GO:0009126 186 0.068
reactive nitrogen species metabolic process GO:2001057 3 0.066
hematopoietic or lymphoid organ development GO:0048534 186 0.066
response to biotic stimulus GO:0009607 276 0.063
response to external biotic stimulus GO:0043207 261 0.061
nucleoside phosphate biosynthetic process GO:1901293 109 0.060
organophosphate biosynthetic process GO:0090407 163 0.058
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.057
regulation of cellular response to stress GO:0080135 244 0.057
negative regulation of programmed cell death GO:0043069 321 0.057
protein catabolic process GO:0030163 325 0.056
regulation of multi organism process GO:0043900 157 0.055
defense response to other organism GO:0098542 129 0.055
cellular response to oxygen containing compound GO:1901701 276 0.055
response to virus GO:0009615 126 0.054
regulation of reactive oxygen species metabolic process GO:2000377 41 0.054
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.053
regulation of nucleoside metabolic process GO:0009118 209 0.051
negative regulation of phosphorus metabolic process GO:0010563 267 0.051
negative regulation of catalytic activity GO:0043086 335 0.051
reactive oxygen species biosynthetic process GO:1903409 4 0.050
regulation of atpase activity GO:0043462 25 0.050
apoptotic signaling pathway GO:0097190 268 0.050
alditol phosphate metabolic process GO:0052646 3 0.049
cellular macromolecule catabolic process GO:0044265 380 0.049
chemical homeostasis GO:0048878 306 0.048
response to nitrogen compound GO:1901698 184 0.048
response to oxygen containing compound GO:1901700 369 0.048
locomotory behavior GO:0007626 1 0.047
amine metabolic process GO:0009308 44 0.047
hemopoiesis GO:0030097 180 0.047
positive regulation of catabolic process GO:0009896 310 0.046
positive regulation of hydrolase activity GO:0051345 331 0.046
cellular modified amino acid metabolic process GO:0006575 64 0.045
reactive oxygen species metabolic process GO:0072593 75 0.045
cell death in response to oxidative stress GO:0036473 29 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.043
regulation of atp catabolic process GO:1903289 25 0.043
apoptotic mitochondrial changes GO:0008637 57 0.043
cellular component morphogenesis GO:0032989 314 0.042
response to radiation GO:0009314 151 0.042
defense response to virus GO:0051607 71 0.042
epithelium development GO:0060429 227 0.041
cell activation GO:0001775 213 0.041
guanosine containing compound metabolic process GO:1901068 244 0.041
protein localization to organelle GO:0033365 280 0.041
carbohydrate metabolic process GO:0005975 207 0.039
response to other organism GO:0051707 261 0.039
positive regulation of cell proliferation GO:0008284 301 0.039
vasodilation GO:0042311 4 0.039
protein maturation GO:0051604 233 0.039
regulation of kinase activity GO:0043549 314 0.039
negative regulation of phosphorylation GO:0042326 174 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.037
defense response GO:0006952 315 0.037
immune system development GO:0002520 195 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
leukocyte differentiation GO:0002521 98 0.037
lipid metabolic process GO:0006629 381 0.037
innate immune response GO:0045087 178 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
negative regulation of phosphate metabolic process GO:0045936 267 0.035
ribonucleotide biosynthetic process GO:0009260 81 0.035
regulation of apoptotic signaling pathway GO:2001233 175 0.034
negative regulation of protein phosphorylation GO:0001933 140 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
regulation of ion transport GO:0043269 189 0.033
single organism cellular localization GO:1902580 332 0.032
positive regulation of immune system process GO:0002684 283 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
signal transduction by phosphorylation GO:0023014 297 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.031
endomembrane system organization GO:0010256 196 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
generation of neurons GO:0048699 152 0.031
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.030
secretion GO:0046903 254 0.030
regulation of immune response GO:0050776 201 0.029
negative regulation of protein kinase activity GO:0006469 98 0.029
regulation of response to external stimulus GO:0032101 222 0.029
protein oligomerization GO:0051259 173 0.029
mapk cascade GO:0000165 288 0.029
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
single organism carbohydrate metabolic process GO:0044723 193 0.029
ion homeostasis GO:0050801 230 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
ion transmembrane transport GO:0034220 338 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
regulation of response to dna damage stimulus GO:2001020 94 0.027
lymphocyte homeostasis GO:0002260 4 0.027
coagulation GO:0050817 78 0.027
divalent inorganic cation transport GO:0072511 158 0.026
regulation of atp metabolic process GO:1903578 29 0.026
regulation of map kinase activity GO:0043405 108 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
neuron differentiation GO:0030182 138 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.026
negative regulation of transferase activity GO:0051348 124 0.026
cell morphogenesis GO:0000902 296 0.026
establishment of protein localization to organelle GO:0072594 172 0.025
cell development GO:0048468 328 0.025
regulation of cell motility GO:2000145 299 0.025
response to ionizing radiation GO:0010212 65 0.025
cell part morphogenesis GO:0032990 137 0.025
regulation of mapk cascade GO:0043408 262 0.024
protein processing GO:0016485 226 0.024
response to organonitrogen compound GO:0010243 156 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
oxidation reduction process GO:0055114 396 0.024
coenzyme biosynthetic process GO:0009108 24 0.024
neuron projection development GO:0031175 106 0.024
alcohol metabolic process GO:0006066 114 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
secretion by cell GO:0032940 226 0.024
mitotic cell cycle GO:0000278 326 0.024
regulation of protein kinase activity GO:0045859 289 0.024
cellular ketone metabolic process GO:0042180 80 0.024
nervous system development GO:0007399 293 0.023
cytoplasmic transport GO:0016482 379 0.023
regulation of protein maturation GO:1903317 150 0.023
cellular response to lipid GO:0071396 127 0.023
regulation of cell development GO:0060284 161 0.023
regulation of cytokine production GO:0001817 232 0.023
cellular protein complex assembly GO:0043623 188 0.023
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.023
protein targeting GO:0006605 187 0.023
neurogenesis GO:0022008 169 0.023
sulfur compound metabolic process GO:0006790 101 0.022
cytokine production GO:0001816 247 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
purine ribonucleotide biosynthetic process GO:0009152 79 0.022
regulation of protein processing GO:0070613 150 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
response to oxidative stress GO:0006979 121 0.022
negative regulation of apoptotic signaling pathway GO:2001234 97 0.022
purine nucleotide biosynthetic process GO:0006164 84 0.022
regulation of cell differentiation GO:0045595 393 0.022
exocytosis GO:0006887 71 0.021
negative regulation of protein processing GO:0010955 142 0.021
regulation of dna metabolic process GO:0051052 153 0.021
blood coagulation GO:0007596 76 0.021
positive regulation of cell differentiation GO:0045597 211 0.021
regulation of anatomical structure size GO:0090066 101 0.021
leukocyte mediated cytotoxicity GO:0001909 27 0.021
coenzyme metabolic process GO:0006732 65 0.021
positive regulation of cell death GO:0010942 263 0.021
ribose phosphate biosynthetic process GO:0046390 82 0.021
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.020
regulation of cell cycle GO:0051726 393 0.020
negative regulation of cell cycle GO:0045786 193 0.020
response to metal ion GO:0010038 84 0.020
negative regulation of protein modification process GO:0031400 200 0.020
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.020
cofactor biosynthetic process GO:0051188 31 0.020
dephosphorylation GO:0016311 209 0.020
peptidyl tyrosine modification GO:0018212 170 0.020
mitotic cell cycle process GO:1903047 286 0.020
positive regulation of response to dna damage stimulus GO:2001022 43 0.020
negative regulation of proteolysis GO:0045861 132 0.020
regulation of immune effector process GO:0002697 91 0.020
negative regulation of t cell apoptotic process GO:0070233 4 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
actin filament based process GO:0030029 224 0.020
nicotinamide nucleotide metabolic process GO:0046496 14 0.019
somatic muscle development GO:0007525 1 0.019
regulation of cellular component movement GO:0051270 334 0.019
oogenesis GO:0048477 2 0.019
regulation of protein catabolic process GO:0042176 155 0.019
hindbrain development GO:0030902 3 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
cell fate determination GO:0001709 3 0.019
regulation of blood vessel size GO:0050880 18 0.019
gtp metabolic process GO:0046039 239 0.019
detection of stimulus GO:0051606 85 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
regulation of neuron apoptotic process GO:0043523 35 0.018
positive regulation of apoptotic signaling pathway GO:2001235 70 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
plasma membrane organization GO:0007009 115 0.018
response to tumor necrosis factor GO:0034612 76 0.018
cellular chemical homeostasis GO:0055082 180 0.018
response to axon injury GO:0048678 1 0.018
peptidyl tyrosine phosphorylation GO:0018108 170 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
activation of immune response GO:0002253 114 0.018
calcium ion transport GO:0006816 147 0.018
memory GO:0007613 3 0.018
regulation of protein localization GO:0032880 296 0.017
blastoderm segmentation GO:0007350 2 0.017
negative regulation of kinase activity GO:0033673 106 0.017
lymphocyte activation GO:0046649 133 0.017
single organism membrane organization GO:0044802 268 0.017
positive regulation of developmental process GO:0051094 314 0.017
response to organic cyclic compound GO:0014070 204 0.017
purine containing compound biosynthetic process GO:0072522 88 0.017
divalent metal ion transport GO:0070838 152 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of neurotransmitter secretion GO:0046928 3 0.017
neurological system process GO:0050877 163 0.017
cellular protein catabolic process GO:0044257 261 0.016
cation transmembrane transport GO:0098655 238 0.016
regulation of locomotion GO:0040012 329 0.016
vesicle mediated transport GO:0016192 371 0.016
interspecies interaction between organisms GO:0044419 156 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
regulation of viral process GO:0050792 103 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
leukocyte activation GO:0045321 164 0.016
mononuclear cell proliferation GO:0032943 71 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
glycerolipid metabolic process GO:0046486 107 0.016
gtp catabolic process GO:0006184 237 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
growth GO:0040007 202 0.016
glutathione metabolic process GO:0006749 20 0.016
cardiovascular system development GO:0072358 262 0.016
regulation of cell migration GO:0030334 289 0.016
intracellular protein transport GO:0006886 270 0.015
response to lipid GO:0033993 206 0.015
segmentation GO:0035282 4 0.015
circulatory system development GO:0072359 262 0.015
female gamete generation GO:0007292 2 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
maintenance of location GO:0051235 112 0.015
regulation of leukocyte activation GO:0002694 115 0.015
negative regulation of protein maturation GO:1903318 142 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
neuron development GO:0048666 113 0.015
regulation of membrane potential GO:0042391 95 0.015
neuron death GO:0070997 65 0.015
glycoprotein metabolic process GO:0009100 110 0.015
negative regulation of developmental process GO:0051093 247 0.015
transition metal ion homeostasis GO:0055076 31 0.015
regulation of intracellular transport GO:0032386 195 0.015
response to increased oxygen levels GO:0036296 4 0.015
regulation of cell cycle process GO:0010564 266 0.014
positive regulation of innate immune response GO:0045089 79 0.014
response to hyperoxia GO:0055093 4 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
biological adhesion GO:0022610 331 0.014
cellular amide metabolic process GO:0043603 69 0.014
cellular lipid metabolic process GO:0044255 303 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
nitrogen compound transport GO:0071705 191 0.014
aging GO:0007568 66 0.014
regulation of response to biotic stimulus GO:0002831 55 0.014
metal ion homeostasis GO:0055065 169 0.014
t cell activation GO:0042110 99 0.014
regulation of protein complex assembly GO:0043254 147 0.014
regulation of response to oxidative stress GO:1902882 26 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
spermatid differentiation GO:0048515 4 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
neuron apoptotic process GO:0051402 39 0.014
hemostasis GO:0007599 76 0.014
cell projection morphogenesis GO:0048858 129 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of mitochondrial membrane potential GO:0051881 23 0.013
vascular process in circulatory system GO:0003018 29 0.013
regulation of neurogenesis GO:0050767 82 0.013
rna interference GO:0016246 4 0.013
regulation of defense response to virus by host GO:0050691 22 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
transmembrane transport GO:0055085 399 0.013
circulatory system process GO:0003013 113 0.013
negative regulation of catabolic process GO:0009895 104 0.013
response to uv GO:0009411 73 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
response to transition metal nanoparticle GO:1990267 29 0.013
sequestering of calcium ion GO:0051208 17 0.013
blood vessel morphogenesis GO:0048514 162 0.013
spermatid development GO:0007286 4 0.013
release of cytochrome c from mitochondria GO:0001836 35 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
ras protein signal transduction GO:0007265 73 0.013
immune response activating signal transduction GO:0002757 90 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
cellular response to molecule of bacterial origin GO:0071219 62 0.013
protein autophosphorylation GO:0046777 123 0.013
activation of innate immune response GO:0002218 55 0.013
deoxyribose phosphate metabolic process GO:0019692 6 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
negative regulation of growth GO:0045926 97 0.012
response to inorganic substance GO:0010035 127 0.012
regulation of cell projection organization GO:0031344 107 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
sequestering of metal ion GO:0051238 24 0.012
single organism reproductive process GO:0044702 98 0.012
response to activity GO:0014823 0 0.012
regulation of proteolysis GO:0030162 293 0.012
response to wounding GO:0009611 168 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
cell adhesion GO:0007155 325 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
lipid localization GO:0010876 106 0.012
negative regulation of transport GO:0051051 176 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
neurotransmitter secretion GO:0007269 4 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
lymphocyte proliferation GO:0046651 70 0.012
protein dna complex subunit organization GO:0071824 80 0.012
cellular response to external stimulus GO:0071496 111 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
protein import GO:0017038 130 0.012
chromatin modification GO:0016568 298 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
embryo development GO:0009790 123 0.012
system process GO:0003008 349 0.012
regulation of meiotic cell cycle GO:0051445 4 0.011
small molecule biosynthetic process GO:0044283 157 0.011
dendrite development GO:0016358 24 0.011
regulation of ion transmembrane transport GO:0034765 132 0.011
translation GO:0006412 132 0.011
regulation of chromosome organization GO:0033044 103 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
regulation of innate immune response GO:0045088 97 0.011
actin cytoskeleton organization GO:0030036 207 0.011
metal ion transport GO:0030001 272 0.011
response to purine containing compound GO:0014074 40 0.011
behavior GO:0007610 112 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
regulation of peptidase activity GO:0052547 180 0.011
neuron projection morphogenesis GO:0048812 50 0.011
cell growth GO:0016049 160 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
cellular homeostasis GO:0019725 196 0.011
negative regulation of oxidative stress induced cell death GO:1903202 17 0.011
regulation of antimicrobial humoral response GO:0002759 1 0.011
negative regulation of mapk cascade GO:0043409 56 0.011
pyridine nucleotide metabolic process GO:0019362 14 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of neuron death GO:1901214 56 0.011
response to oxygen levels GO:0070482 100 0.011
fat cell differentiation GO:0045444 32 0.011
cation homeostasis GO:0055080 189 0.011
oxidoreduction coenzyme metabolic process GO:0006733 19 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
primary neural tube formation GO:0014020 3 0.011
myeloid leukocyte differentiation GO:0002573 60 0.011
cation transport GO:0006812 331 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
glycosylation GO:0070085 71 0.011
cell cycle phase transition GO:0044770 173 0.011
cytosolic calcium ion transport GO:0060401 48 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
regulation of tube size GO:0035150 18 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
glycerolipid biosynthetic process GO:0045017 51 0.011
membrane lipid metabolic process GO:0006643 53 0.011
regulation of body fluid levels GO:0050878 99 0.011
cell cycle arrest GO:0007050 71 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of metal ion transport GO:0010959 120 0.011
protein ubiquitination GO:0016567 314 0.011
regulation of cytoplasmic transport GO:1903649 149 0.010
small molecule catabolic process GO:0044282 92 0.010
cellular response to extracellular stimulus GO:0031668 72 0.010
peptide metabolic process GO:0006518 51 0.010
positive regulation of transport GO:0051050 336 0.010
membrane organization GO:0061024 292 0.010
myosin filament organization GO:0031033 2 0.010
regulation of lymphocyte activation GO:0051249 103 0.010
digestive tract development GO:0048565 75 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
positive regulation of cell motility GO:2000147 177 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
adaptive immune response GO:0002250 49 0.010
regulation of protein polymerization GO:0032271 63 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of protein transport GO:0051223 213 0.010
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.010
endocytosis GO:0006897 159 0.010
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.010
regulation of defense response to virus GO:0050688 33 0.010
regulation of binding GO:0051098 111 0.010

GCH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.026
cancer DOID:162 167 0.023
organ system cancer DOID:0050686 164 0.021
immune system disease DOID:2914 155 0.015
musculoskeletal system disease DOID:17 223 0.015
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012
eye and adnexa disease DOID:1492 150 0.010