Homo sapiens

35 known processes

GEMIN4

gem (nuclear organelle) associated protein 4

(Aliases: p97,HHRF-1,HCAP1,DKFZp434B131,DKFZp434D174,HC56)

GEMIN4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spliceosomal snrnp assembly GO:0000387 28 0.989
rna processing GO:0006396 255 0.878
ribonucleoprotein complex assembly GO:0022618 78 0.690
cellular macromolecular complex assembly GO:0034622 324 0.538
ribonucleoprotein complex subunit organization GO:0071826 81 0.495
multicellular organismal aging GO:0010259 3 0.484
rna splicing GO:0008380 131 0.450
ribonucleoprotein complex biogenesis GO:0022613 116 0.287
regulation of cell cycle GO:0051726 393 0.250
cellular component morphogenesis GO:0032989 314 0.242
mrna metabolic process GO:0016071 175 0.199
positive regulation of apoptotic process GO:0043065 246 0.179
post embryonic development GO:0009791 2 0.176
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.161
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.144
negative regulation of cell cycle GO:0045786 193 0.131
production of sirna involved in rna interference GO:0030422 3 0.129
ncrna metabolic process GO:0034660 108 0.121
female gamete generation GO:0007292 2 0.118
oogenesis GO:0048477 2 0.118
cell activation GO:0001775 213 0.114
cellular component assembly involved in morphogenesis GO:0010927 73 0.113
cell division GO:0051301 168 0.101
purine nucleoside monophosphate catabolic process GO:0009128 158 0.095
cell development GO:0048468 328 0.091
organelle fission GO:0048285 149 0.090
purine nucleotide catabolic process GO:0006195 405 0.088
organelle assembly GO:0070925 176 0.086
purine ribonucleoside metabolic process GO:0046128 437 0.077
determination of adult lifespan GO:0008340 2 0.076
protein ubiquitination GO:0016567 314 0.073
single organism cellular localization GO:1902580 332 0.072
growth GO:0040007 202 0.072
endocytosis GO:0006897 159 0.071
mitotic cell cycle process GO:1903047 286 0.070
single organism reproductive process GO:0044702 98 0.069
mrna processing GO:0006397 133 0.068
ribonucleoside triphosphate catabolic process GO:0009203 391 0.066
defense response GO:0006952 315 0.065
nucleoside monophosphate metabolic process GO:0009123 191 0.063
anatomical structure formation involved in morphogenesis GO:0048646 284 0.063
mrna splicing via spliceosome GO:0000398 89 0.062
nucleocytoplasmic transport GO:0006913 176 0.062
nucleoside triphosphate catabolic process GO:0009143 394 0.061
production of small rna involved in gene silencing by rna GO:0070918 13 0.058
purine containing compound catabolic process GO:0072523 411 0.058
positive regulation of programmed cell death GO:0043068 249 0.055
negative regulation of developmental process GO:0051093 247 0.054
single organism membrane organization GO:0044802 268 0.051
actin filament based process GO:0030029 224 0.051
mitotic cell cycle GO:0000278 326 0.051
rna splicing via transesterification reactions GO:0000375 90 0.051
lipid biosynthetic process GO:0008610 177 0.051
lipid metabolic process GO:0006629 381 0.050
vesicle mediated transport GO:0016192 371 0.050
regulation of mrna metabolic process GO:1903311 53 0.050
protein localization to organelle GO:0033365 280 0.050
oocyte differentiation GO:0009994 2 0.050
mitochondrion organization GO:0007005 156 0.048
protein targeting GO:0006605 187 0.048
ras protein signal transduction GO:0007265 73 0.047
striated muscle cell development GO:0055002 27 0.046
response to wounding GO:0009611 168 0.046
myosin filament organization GO:0031033 2 0.045
regulation of meiotic cell cycle GO:0051445 4 0.044
positive regulation of cell death GO:0010942 263 0.044
posttranscriptional regulation of gene expression GO:0010608 213 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
apoptotic signaling pathway GO:0097190 268 0.040
regulation of mrna processing GO:0050684 48 0.039
nucleoside triphosphate metabolic process GO:0009141 422 0.039
microtubule based process GO:0007017 210 0.039
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
intracellular protein transport GO:0006886 270 0.038
primary mirna processing GO:0031053 3 0.038
steroid biosynthetic process GO:0006694 46 0.037
rna interference GO:0016246 4 0.037
dna repair GO:0006281 198 0.035
regeneration GO:0031099 4 0.035
regulation of cell cycle process GO:0010564 266 0.034
striated muscle myosin thick filament assembly GO:0071688 2 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.033
myosin filament assembly GO:0031034 2 0.033
nuclear division GO:0000280 128 0.032
cardiovascular system development GO:0072358 262 0.032
reproductive process GO:0022414 106 0.031
developmental process involved in reproduction GO:0003006 66 0.030
regulation of lipid metabolic process GO:0019216 96 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
regulation of steroid biosynthetic process GO:0050810 23 0.029
ribonucleoside monophosphate metabolic process GO:0009161 187 0.029
nuclear transport GO:0051169 179 0.029
negative regulation of protein metabolic process GO:0051248 391 0.028
blastocyst development GO:0001824 3 0.028
atp metabolic process GO:0046034 176 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.027
behavior GO:0007610 112 0.026
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.026
response to oxygen containing compound GO:1901700 369 0.026
protein oligomerization GO:0051259 173 0.026
negative regulation of protein modification process GO:0031400 200 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
defense response to other organism GO:0098542 129 0.025
lymphocyte activation GO:0046649 133 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
nucleotide catabolic process GO:0009166 408 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
maturation of lsu rrna GO:0000470 3 0.024
nucleus organization GO:0006997 28 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
microtubule cytoskeleton organization GO:0000226 176 0.024
circulatory system development GO:0072359 262 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
regulation of protein localization GO:0032880 296 0.023
muscle cell differentiation GO:0042692 63 0.023
tube development GO:0035295 125 0.023
regulation of gene expression epigenetic GO:0040029 73 0.023
response to nitrogen compound GO:1901698 184 0.022
reproduction GO:0000003 63 0.022
regulation of transferase activity GO:0051338 355 0.022
cell part morphogenesis GO:0032990 137 0.022
cell morphogenesis GO:0000902 296 0.022
establishment of protein localization to organelle GO:0072594 172 0.022
striated muscle cell differentiation GO:0051146 43 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
aging GO:0007568 66 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
protein maturation GO:0051604 233 0.021
defense response to bacterium GO:0042742 63 0.021
cell projection morphogenesis GO:0048858 129 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
cellular response to organic cyclic compound GO:0071407 127 0.020
cell morphogenesis involved in differentiation GO:0000904 144 0.020
embryo development GO:0009790 123 0.020
oocyte development GO:0048599 1 0.020
gene silencing by mirna GO:0035195 23 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
nervous system development GO:0007399 293 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
cytoplasmic transport GO:0016482 379 0.018
receptor mediated endocytosis GO:0006898 84 0.018
generation of neurons GO:0048699 152 0.018
immune response GO:0006955 307 0.018
response to organic cyclic compound GO:0014070 204 0.017
regulation of locomotion GO:0040012 329 0.017
actin cytoskeleton organization GO:0030036 207 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
regulation of mitotic cell cycle GO:0007346 189 0.016
atp catabolic process GO:0006200 157 0.016
centrosome organization GO:0051297 58 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
cell type specific apoptotic process GO:0097285 125 0.016
sensory organ development GO:0007423 52 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
cytokine production GO:0001816 247 0.016
central nervous system development GO:0007417 123 0.015
negative regulation of viral process GO:0048525 66 0.015
gene silencing by rna GO:0031047 26 0.015
negative regulation of cell death GO:0060548 345 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
blastoderm segmentation GO:0007350 2 0.015
organ morphogenesis GO:0009887 147 0.015
negative regulation of defense response GO:0031348 47 0.014
nucleoside catabolic process GO:0009164 408 0.014
mitochondrial translation GO:0032543 17 0.014
regulation of cellular component movement GO:0051270 334 0.014
leukocyte activation GO:0045321 164 0.014
taxis GO:0042330 157 0.014
response to uv GO:0009411 73 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
cellular response to dna damage stimulus GO:0006974 379 0.013
embryonic morphogenesis GO:0048598 85 0.013
regulation of innate immune response GO:0045088 97 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
epithelium development GO:0060429 227 0.013
neuron development GO:0048666 113 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
macromolecule methylation GO:0043414 97 0.013
protein alkylation GO:0008213 74 0.013
ncrna processing GO:0034470 83 0.013
ossification GO:0001503 121 0.013
developmental growth GO:0048589 48 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
reproductive system development GO:0061458 56 0.012
multi organism reproductive process GO:0044703 54 0.012
cell projection organization GO:0030030 252 0.012
protein processing GO:0016485 226 0.011
posttranscriptional gene silencing GO:0016441 25 0.011
regulation of immune response GO:0050776 201 0.011
response to oxygen levels GO:0070482 100 0.011
actomyosin structure organization GO:0031032 59 0.011
regulation of cell growth GO:0001558 135 0.011
response to biotic stimulus GO:0009607 276 0.011
cellular protein complex assembly GO:0043623 188 0.011
negative regulation of response to wounding GO:1903035 47 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of protein kinase activity GO:0045859 289 0.011
spermatid differentiation GO:0048515 4 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.011
multicellular organism reproduction GO:0032504 42 0.011
meiotic nuclear division GO:0007126 10 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
organophosphate catabolic process GO:0046434 430 0.011
posttranscriptional gene silencing by rna GO:0035194 25 0.011
cell growth GO:0016049 160 0.011
regulation of kinase activity GO:0043549 314 0.011
positive regulation of protein transport GO:0051222 135 0.011
response to bacterium GO:0009617 144 0.010
regulation of rna splicing GO:0043484 62 0.010
segmentation GO:0035282 4 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
muscle structure development GO:0061061 98 0.010
cellular ketone metabolic process GO:0042180 80 0.010
methylation GO:0032259 106 0.010
compound eye development GO:0048749 1 0.010

GEMIN4 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.059
nervous system disease DOID:863 431 0.059
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
neurodegenerative disease DOID:1289 102 0.014