|
|
regulation of interleukin 6 mediated signaling pathway
|
GO:0070103 |
3 |
1.000
|
|
|
|
regulation of hepatocyte growth factor receptor signaling pathway
|
GO:1902202 |
4 |
1.000
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.999
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.999
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.999
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.998
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.998
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.997
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.996
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.996
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.995
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.995
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.995
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.994
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.993
|
|
|
|
negative regulation of type i interferon mediated signaling pathway
|
GO:0060339 |
4 |
0.990
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.990
|
|
|
|
platelet derived growth factor receptor beta signaling pathway
|
GO:0035791 |
4 |
0.989
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.988
|
Mouse |
|
|
negative regulation of macrophage differentiation
|
GO:0045650 |
2 |
0.988
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.986
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.985
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.985
|
Mouse Rat |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.979
|
Rat |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.978
|
Mouse Rat |
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.977
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.974
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.973
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.973
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.972
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.967
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.957
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.956
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.955
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.955
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.954
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.952
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.946
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.943
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.938
|
Rat |
|
|
cellular response to interleukin 15
|
GO:0071350 |
6 |
0.935
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.933
|
Mouse Rat |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.933
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.933
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.929
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.926
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
14 |
0.923
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.904
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.896
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.895
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.892
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.881
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.873
|
|
|
|
response to interleukin 15
|
GO:0070672 |
6 |
0.869
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.862
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.861
|
Rat |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.858
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.855
|
Mouse |
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.852
|
|
|
|
growth
|
GO:0040007 |
202 |
0.851
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.849
|
Rat |
|
|
negative regulation of interleukin 6 mediated signaling pathway
|
GO:0070104 |
2 |
0.849
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.848
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.847
|
Human Rat |
|
|
cellular response to interleukin 4
|
GO:0071353 |
7 |
0.843
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.828
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.821
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.807
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.794
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.791
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.791
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.790
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.788
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.785
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.785
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.768
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.767
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.761
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.760
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.759
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.743
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.740
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.738
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.735
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.726
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.711
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.711
|
Mouse Rat |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.708
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.702
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.701
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.697
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.695
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.694
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.692
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.682
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.677
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.676
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
12 |
0.675
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.665
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
12 |
0.655
|
|
|
|
response to interleukin 4
|
GO:0070670 |
7 |
0.649
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.641
|
Human Rat |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.636
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.633
|
Mouse Rat |
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.632
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.624
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.623
|
|
|
|
response to macrophage colony stimulating factor
|
GO:0036005 |
4 |
0.621
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.616
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.600
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.589
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.587
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.580
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.578
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.570
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.570
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.567
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.560
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.557
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.549
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.546
|
Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.545
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.542
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.541
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.525
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.491
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.485
|
|
|
|
regulation of action potential
|
GO:0098900 |
2 |
0.480
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.471
|
Rat |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.470
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.468
|
Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.463
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.462
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.458
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.458
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.457
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.454
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.445
|
Rat |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.445
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.438
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.437
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.433
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.433
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.431
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.430
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.430
|
|
|
|
memory
|
GO:0007613 |
3 |
0.419
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.417
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.415
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.413
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.409
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.405
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.402
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.402
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.402
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.401
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.390
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.386
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.386
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.375
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.373
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.369
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.368
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.366
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.363
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.360
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.358
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.357
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.354
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.334
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.334
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.333
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.333
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.322
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.319
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.318
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.314
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.314
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.311
|
Human Rat |
|
|
blood circulation
|
GO:0008015 |
113 |
0.307
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.307
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.303
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.303
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.300
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.300
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.299
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.290
|
Human Rat |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.287
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.286
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.286
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.284
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.275
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.274
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.272
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.269
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.268
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.267
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.266
|
Rat |
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.265
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.264
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.264
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.262
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.261
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.261
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.260
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.260
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.259
|
Rat |
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.259
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.257
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.257
|
|
|
|
system process
|
GO:0003008 |
349 |
0.254
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.253
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.252
|
Mouse |
|
|
renal system development
|
GO:0072001 |
63 |
0.251
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.249
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.247
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.240
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.239
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.229
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.228
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.227
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.225
|
Rat |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.221
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.220
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.219
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.215
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.215
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.214
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.212
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.210
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.209
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.209
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.204
|
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.203
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.201
|
Human Mouse Rat |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.201
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.200
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.199
|
|
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
0.197
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.196
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.196
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.195
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.194
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.191
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.186
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.181
|
|
|
|
body fluid secretion
|
GO:0007589 |
9 |
0.181
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.181
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.179
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.177
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.176
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.173
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.172
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.172
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.172
|
Rat |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.171
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.171
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.170
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.167
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.167
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.165
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.165
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.164
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.164
|
|
|
|
lymph vessel morphogenesis
|
GO:0036303 |
7 |
0.163
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.163
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.163
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.162
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.162
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.161
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.161
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.160
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.159
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.158
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.157
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.157
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.156
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.154
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.153
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.152
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.152
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.152
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.152
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
16 |
0.151
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.147
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.144
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.142
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.141
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.141
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.141
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.141
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.141
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.140
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.140
|
|
|
|
negative regulation of membrane protein ectodomain proteolysis
|
GO:0051045 |
4 |
0.139
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.136
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
8 |
0.136
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.135
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.135
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.134
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.134
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.133
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.133
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.132
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.130
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.128
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.128
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.127
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.125
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.125
|
|
|
|
negative regulation of t cell differentiation in thymus
|
GO:0033085 |
2 |
0.123
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.123
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.122
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.122
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.122
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.121
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.121
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.121
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.121
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.120
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.119
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.119
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.119
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.118
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.117
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.115
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.114
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.114
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.114
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.113
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
1 |
0.113
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.113
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.112
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.112
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.112
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.112
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.112
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.111
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.111
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.110
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.109
|
|
|
|
positive regulation of muscle cell apoptotic process
|
GO:0010661 |
4 |
0.109
|
|
|
|
response to type i interferon
|
GO:0034340 |
14 |
0.108
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.107
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.107
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.106
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.104
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.103
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.102
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.101
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.100
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.100
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.099
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.099
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.099
|
|
|
|
cellular response to ph
|
GO:0071467 |
9 |
0.099
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.098
|
Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.096
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.096
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.095
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.095
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.094
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.094
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.094
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.093
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.093
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.093
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.091
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.091
|
|
|
|
negative regulation of vascular permeability
|
GO:0043116 |
7 |
0.091
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.090
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.089
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.089
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.088
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.088
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.088
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.088
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.087
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.086
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.086
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.085
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.085
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.084
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.083
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.083
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.082
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.082
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.082
|
Rat |
|
|
single organism behavior
|
GO:0044708 |
28 |
0.081
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.081
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.080
|
|
|
|
negative regulation of response to interferon gamma
|
GO:0060331 |
2 |
0.080
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.079
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.079
|
|
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.078
|
|
|
|
positive regulation of phosphoprotein phosphatase activity
|
GO:0032516 |
9 |
0.078
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.078
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.078
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.077
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.077
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.076
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.076
|
|
|
|
negative regulation of chemotaxis
|
GO:0050922 |
13 |
0.075
|
|
|
|
regulation of cardiac muscle cell apoptotic process
|
GO:0010665 |
3 |
0.075
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.074
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.074
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.074
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.074
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.072
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.072
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.072
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.072
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.071
|
|
|
|
lymph vessel development
|
GO:0001945 |
9 |
0.071
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.071
|
Human Rat |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.070
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.070
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.069
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.069
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.068
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.068
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.067
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.067
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.067
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.067
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.066
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.066
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.066
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
6 |
0.066
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.065
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.064
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.064
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.064
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.064
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.063
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.063
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.062
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.062
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.062
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.061
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.061
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.061
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.061
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.061
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.061
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.060
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.060
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
11 |
0.060
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.060
|
Rat |
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.059
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.059
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.059
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.058
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.058
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.058
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.057
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.057
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.057
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.057
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.057
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.057
|
Rat |
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.057
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.055
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.055
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.055
|
|
|
|
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling
|
GO:0060665 |
1 |
0.055
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.054
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.054
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.054
|
|
|
|
response to ph
|
GO:0009268 |
12 |
0.053
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.053
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.053
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.053
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.052
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.052
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.052
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.051
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.051
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.051
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.051
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.050
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.050
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.050
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.050
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.050
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.050
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.049
|
|
