Homo sapiens

118 known processes

GLUD1

glutamate dehydrogenase 1

(Aliases: GDH,GLUD,MGC132003,GDH1)

GLUD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.358
post embryonic development GO:0009791 2 0.259
oxidation reduction process GO:0055114 396 0.244
cellular amino acid biosynthetic process GO:0008652 30 0.238
glutamate metabolic process GO:0006536 10 0.223
organic acid catabolic process GO:0016054 71 0.218
multicellular organismal aging GO:0010259 3 0.185
carboxylic acid biosynthetic process GO:0046394 97 0.153
small molecule catabolic process GO:0044282 92 0.147
carboxylic acid catabolic process GO:0046395 71 0.144
tricarboxylic acid metabolic process GO:0072350 4 0.137
Mouse
determination of adult lifespan GO:0008340 2 0.124
organonitrogen compound biosynthetic process GO:1901566 200 0.116
dicarboxylic acid metabolic process GO:0043648 29 0.105
glutamine family amino acid catabolic process GO:0009065 8 0.102
dicarboxylic acid biosynthetic process GO:0043650 4 0.097
cellular amino acid catabolic process GO:0009063 31 0.088
secretion GO:0046903 254 0.078
alpha amino acid catabolic process GO:1901606 26 0.075
regulation of secretion GO:0051046 194 0.074
growth GO:0040007 202 0.070
Worm
regulation of hormone levels GO:0010817 125 0.068
cellular ketone metabolic process GO:0042180 80 0.066
cellular amine metabolic process GO:0044106 41 0.060
purine ribonucleoside metabolic process GO:0046128 437 0.059
secretion by cell GO:0032940 226 0.058
lipid metabolic process GO:0006629 381 0.055
purine ribonucleoside catabolic process GO:0046130 398 0.054
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
positive regulation of transport GO:0051050 336 0.053
vesicle mediated transport GO:0016192 371 0.052
purine nucleotide catabolic process GO:0006195 405 0.052
organophosphate catabolic process GO:0046434 430 0.052
alpha amino acid biosynthetic process GO:1901607 23 0.052
regulation of secretion by cell GO:1903530 177 0.050
nervous system development GO:0007399 293 0.050
ribonucleotide catabolic process GO:0009261 405 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.050
nucleoside catabolic process GO:0009164 408 0.050
positive regulation of secretion GO:0051047 116 0.048
glutamine family amino acid metabolic process GO:0009064 17 0.048
locomotory behavior GO:0007626 1 0.048
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
ion homeostasis GO:0050801 230 0.048
nucleoside triphosphate catabolic process GO:0009143 394 0.047
regulation of cellular amine metabolic process GO:0033238 11 0.045
single organism membrane organization GO:0044802 268 0.045
amine metabolic process GO:0009308 44 0.045
negative regulation of catalytic activity GO:0043086 335 0.044
ribonucleoside triphosphate metabolic process GO:0009199 412 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.042
purine ribonucleotide catabolic process GO:0009154 404 0.042
positive regulation of secretion by cell GO:1903532 108 0.039
purine containing compound catabolic process GO:0072523 411 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.037
cellular homeostasis GO:0019725 196 0.037
glycosyl compound catabolic process GO:1901658 413 0.037
regulation of transferase activity GO:0051338 355 0.037
response to wounding GO:0009611 168 0.036
negative regulation of protein metabolic process GO:0051248 391 0.035
small molecule biosynthetic process GO:0044283 157 0.035
cation transport GO:0006812 331 0.035
midbrain development GO:0030901 45 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
ras protein signal transduction GO:0007265 73 0.034
guanosine containing compound metabolic process GO:1901068 244 0.034
system process GO:0003008 349 0.034
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
negative regulation of hydrolase activity GO:0051346 182 0.033
single organism cellular localization GO:1902580 332 0.032
mitochondrion organization GO:0007005 156 0.032
protein localization to organelle GO:0033365 280 0.032
regulation of kinase activity GO:0043549 314 0.032
cellular cation homeostasis GO:0030003 163 0.031
nucleoside monophosphate metabolic process GO:0009123 191 0.031
memory GO:0007613 3 0.031
ribonucleoside catabolic process GO:0042454 406 0.031
regulation of nucleotide metabolic process GO:0006140 269 0.031
central nervous system development GO:0007417 123 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
chemical homeostasis GO:0048878 306 0.030
cellular component morphogenesis GO:0032989 314 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
rab protein signal transduction GO:0032482 4 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
nucleotide catabolic process GO:0009166 408 0.030
peptide secretion GO:0002790 51 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
regulation of hormone secretion GO:0046883 57 0.029
endomembrane system organization GO:0010256 196 0.029
inorganic ion transmembrane transport GO:0098660 231 0.029
cation homeostasis GO:0055080 189 0.029
transmembrane transport GO:0055085 399 0.029
organic hydroxy compound metabolic process GO:1901615 147 0.029
peripheral nervous system development GO:0007422 2 0.029
biological adhesion GO:0022610 331 0.028
actin cytoskeleton organization GO:0030036 207 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
positive regulation of catabolic process GO:0009896 310 0.028
nitrogen compound transport GO:0071705 191 0.028
regulation of locomotion GO:0040012 329 0.027
peptide transport GO:0015833 74 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
cytoplasmic transport GO:0016482 379 0.027
protein maturation GO:0051604 233 0.027
membrane organization GO:0061024 292 0.027
alcohol metabolic process GO:0006066 114 0.027
neuromuscular junction development GO:0007528 3 0.027
cellular ion homeostasis GO:0006873 168 0.027
cellular lipid metabolic process GO:0044255 303 0.026
positive regulation of developmental process GO:0051094 314 0.026
response to abiotic stimulus GO:0009628 336 0.026
protein localization to membrane GO:0072657 160 0.026
cell morphogenesis GO:0000902 296 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
amide transport GO:0042886 76 0.025
regulation of protein localization GO:0032880 296 0.025
immune response GO:0006955 307 0.025
regulation of gtpase activity GO:0043087 180 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
intracellular protein transport GO:0006886 270 0.025
cellular chemical homeostasis GO:0055082 180 0.025
female gamete generation GO:0007292 2 0.025
regulation of cellular component movement GO:0051270 334 0.025
gtp catabolic process GO:0006184 237 0.025
regulation of cell migration GO:0030334 289 0.024
maintenance of location GO:0051235 112 0.024
peptide hormone secretion GO:0030072 50 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
cell adhesion GO:0007155 325 0.024
cell development GO:0048468 328 0.024
substantia nigra development GO:0021762 45 0.024
positive regulation of programmed cell death GO:0043068 249 0.023
regulation of insulin secretion GO:0050796 33 0.023
apoptotic signaling pathway GO:0097190 268 0.023
ion transmembrane transport GO:0034220 338 0.023
regulation of protein kinase activity GO:0045859 289 0.023
positive regulation of transferase activity GO:0051347 227 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
segmentation GO:0035282 4 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
hormone transport GO:0009914 68 0.022
lipid localization GO:0010876 106 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
ribonucleoside monophosphate catabolic process GO:0009158 158 0.022
protein targeting GO:0006605 187 0.022
protein ubiquitination GO:0016567 314 0.021
positive regulation of cell death GO:0010942 263 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
oogenesis GO:0048477 2 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
establishment of protein localization to membrane GO:0090150 121 0.021
endocytosis GO:0006897 159 0.021
brain development GO:0007420 97 0.021
regulation of cell motility GO:2000145 299 0.021
regulation of peptidase activity GO:0052547 180 0.020
gtp metabolic process GO:0046039 239 0.020
epithelial cell differentiation GO:0030855 141 0.020
mating GO:0007618 1 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
regulation of proteolysis GO:0030162 293 0.020
fatty acid metabolic process GO:0006631 115 0.020
cation transmembrane transport GO:0098655 238 0.020
metal ion homeostasis GO:0055065 169 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
defense response GO:0006952 315 0.019
metal ion transport GO:0030001 272 0.019
protein processing GO:0016485 226 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
response to axon injury GO:0048678 1 0.019
actin filament based process GO:0030029 224 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
regulation of protein maturation GO:1903317 150 0.019
negative regulation of proteolysis GO:0045861 132 0.019
endosomal transport GO:0016197 129 0.019
negative regulation of protein maturation GO:1903318 142 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
epithelium development GO:0060429 227 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
neural nucleus development GO:0048857 47 0.018
cell projection organization GO:0030030 252 0.018
embryo development GO:0009790 123 0.018
anterior posterior axis specification GO:0009948 2 0.018
spermatid differentiation GO:0048515 4 0.018
negative regulation of cell death GO:0060548 345 0.018
inorganic cation transmembrane transport GO:0098662 194 0.018
negative regulation of protein processing GO:0010955 142 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
atp metabolic process GO:0046034 176 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
monocarboxylic acid metabolic process GO:0032787 185 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
regulation of peptide hormone secretion GO:0090276 41 0.018
cellular protein catabolic process GO:0044257 261 0.018
regulation of growth GO:0040008 165 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
cellular response to endogenous stimulus GO:0071495 336 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
hindbrain development GO:0030902 3 0.017
plasma membrane organization GO:0007009 115 0.017
insulin secretion GO:0030073 39 0.017
somitogenesis GO:0001756 2 0.017
adult locomotory behavior GO:0008344 1 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
microtubule based process GO:0007017 210 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
neurological system process GO:0050877 163 0.017
carbohydrate metabolic process GO:0005975 207 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
coenzyme metabolic process GO:0006732 65 0.017
response to oxygen containing compound GO:1901700 369 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
regulation of protein processing GO:0070613 150 0.017
regulation of vesicle mediated transport GO:0060627 130 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
steroid metabolic process GO:0008202 94 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
blastoderm segmentation GO:0007350 2 0.016
regeneration GO:0031099 4 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
regulation of cell differentiation GO:0045595 393 0.016
nerve development GO:0021675 4 0.016
protein oligomerization GO:0051259 173 0.016
innate immune response GO:0045087 178 0.016
cellular protein complex assembly GO:0043623 188 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
cell part morphogenesis GO:0032990 137 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
protein catabolic process GO:0030163 325 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
regulation of cellular response to stress GO:0080135 244 0.016
response to other organism GO:0051707 261 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
positive regulation of organelle organization GO:0010638 195 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
mapk cascade GO:0000165 288 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
nuclear transport GO:0051169 179 0.015
organic acid biosynthetic process GO:0016053 97 0.015
cell growth GO:0016049 160 0.015
rho protein signal transduction GO:0007266 26 0.015
response to nitrogen compound GO:1901698 184 0.015
divalent metal ion transport GO:0070838 152 0.015
divalent inorganic cation transport GO:0072511 158 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
protein targeting to membrane GO:0006612 42 0.015
regulation of cell growth GO:0001558 135 0.015
cardiovascular system development GO:0072358 262 0.015
negative regulation of protein modification process GO:0031400 200 0.015
cofactor metabolic process GO:0051186 87 0.015
cardiac muscle cell contraction GO:0086003 4 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
positive regulation of kinase activity GO:0033674 204 0.014
spermatid development GO:0007286 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
associative learning GO:0008306 1 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
mitotic cell cycle GO:0000278 326 0.014
regulation of cell cycle GO:0051726 393 0.014
atp catabolic process GO:0006200 157 0.014
response to hormone GO:0009725 175 0.014
response to biotic stimulus GO:0009607 276 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
sulfur compound metabolic process GO:0006790 101 0.014
glutamine metabolic process GO:0006541 2 0.014
Yeast Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
neural tube formation GO:0001841 3 0.013
sensory perception of pain GO:0019233 4 0.013
motor neuron axon guidance GO:0008045 2 0.013
visual behavior GO:0007632 2 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
anion transport GO:0006820 161 0.013
hemopoiesis GO:0030097 180 0.013
actin mediated cell contraction GO:0070252 12 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
limbic system development GO:0021761 3 0.013
cell division GO:0051301 168 0.013
cell substrate adhesion GO:0031589 132 0.013
generation of neurons GO:0048699 152 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
response to oxidative stress GO:0006979 121 0.013
neuron projection development GO:0031175 106 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of multi organism process GO:0043900 157 0.013
lipid biosynthetic process GO:0008610 177 0.013
rna interference GO:0016246 4 0.013
regulation of membrane potential GO:0042391 95 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
tissue regeneration GO:0042246 3 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
regulation of transmembrane transport GO:0034762 139 0.013
regulation of actin filament based process GO:0032970 141 0.013
reproduction GO:0000003 63 0.013
Worm
vasculature development GO:0001944 181 0.013
regulation of cell adhesion GO:0030155 166 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
engulfment of apoptotic cell GO:0043652 2 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
oocyte development GO:0048599 1 0.013
regulation of cell cycle process GO:0010564 266 0.013
negative regulation of transport GO:0051051 176 0.013
neurogenesis GO:0022008 169 0.013
tube closure GO:0060606 3 0.012
dephosphorylation GO:0016311 209 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
neuron differentiation GO:0030182 138 0.012
negative regulation of organelle organization GO:0010639 126 0.012
primary neural tube formation GO:0014020 3 0.012
cellular modified amino acid metabolic process GO:0006575 64 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
wound healing GO:0042060 115 0.012
neurotransmitter secretion GO:0007269 4 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
interspecies interaction between organisms GO:0044419 156 0.012
lipid catabolic process GO:0016042 84 0.012
cell projection morphogenesis GO:0048858 129 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
immune system development GO:0002520 195 0.012
mitotic cell cycle process GO:1903047 286 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
positive regulation of hormone secretion GO:0046887 25 0.012
response to radiation GO:0009314 151 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
oocyte differentiation GO:0009994 2 0.012
negative regulation of transferase activity GO:0051348 124 0.012
cerebral cortex cell migration GO:0021795 3 0.012
regulation of protein complex assembly GO:0043254 147 0.012
glycoprotein metabolic process GO:0009100 110 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
viral life cycle GO:0019058 132 0.012
cellular amide metabolic process GO:0043603 69 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
visual learning GO:0008542 1 0.011
cell projection assembly GO:0030031 126 0.011
multi organism cellular process GO:0044764 156 0.011
single organism cell adhesion GO:0098602 179 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
negative regulation of kinase activity GO:0033673 106 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
calcium ion transport GO:0006816 147 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
regulation of neurogenesis GO:0050767 82 0.011
regulation of binding GO:0051098 111 0.011
chromatin modification GO:0016568 298 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
cellular lipid catabolic process GO:0044242 65 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.011
head development GO:0060322 108 0.011
receptor mediated endocytosis GO:0006898 84 0.011
lipid oxidation GO:0034440 33 0.011
angiogenesis GO:0001525 147 0.011
regulation of mapk cascade GO:0043408 262 0.011
calcium ion transmembrane transport GO:0070588 76 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
regulation of ion transport GO:0043269 189 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
organic anion transport GO:0015711 103 0.011
protein localization to plasma membrane GO:0072659 93 0.011
cell activation GO:0001775 213 0.011
response to extracellular stimulus GO:0009991 85 0.011
organ morphogenesis GO:0009887 147 0.011
response to bacterium GO:0009617 144 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
positive regulation of insulin secretion GO:0032024 10 0.011
regulation of immune response GO:0050776 201 0.011
viral process GO:0016032 146 0.011
synaptic vesicle recycling GO:0036465 3 0.011
regulation of transporter activity GO:0032409 82 0.011
actin filament organization GO:0007015 128 0.011
cytokinesis GO:0000910 96 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
negative regulation of locomotion GO:0040013 118 0.011
regulation of intracellular transport GO:0032386 195 0.010
regulation of defense response GO:0031347 154 0.010
metencephalon development GO:0022037 2 0.010
aging GO:0007568 66 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
response to organic cyclic compound GO:0014070 204 0.010
regulation of ion transmembrane transporter activity GO:0032412 72 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
chromatin organization GO:0006325 351 0.010
regulation of response to external stimulus GO:0032101 222 0.010
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.010
cell cell signaling GO:0007267 155 0.010
negative regulation of axon extension GO:0030517 2 0.010

GLUD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.031
amino acid metabolic disorder DOID:9252 50 0.031
inherited metabolic disorder DOID:655 242 0.031
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
disease of cellular proliferation DOID:14566 174 0.018
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.016
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
musculoskeletal system disease DOID:17 223 0.012
carbohydrate metabolic disorder DOID:2978 55 0.003
hyperinsulinemic hypoglycemia DOID:13317 7 0.001