Homo sapiens

0 known processes

GMFB

glia maturation factor, beta

(Aliases: GMF)

GMFB biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rho gtpase activity GO:0034259 4 0.700
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.698
organophosphate biosynthetic process GO:0090407 163 0.549
purine nucleoside catabolic process GO:0006152 398 0.520
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.441
secretion GO:0046903 254 0.426
cell fate determination GO:0001709 3 0.378
positive regulation of camp biosynthetic process GO:0030819 35 0.322
camp metabolic process GO:0046058 61 0.318
regulation of kinase activity GO:0043549 314 0.266
cellular lipid metabolic process GO:0044255 303 0.251
secretion by cell GO:0032940 226 0.248
positive regulation of phosphorylation GO:0042327 394 0.194
positive regulation of map kinase activity GO:0043406 80 0.192
camp biosynthetic process GO:0006171 47 0.186
post embryonic development GO:0009791 2 0.185
female gamete generation GO:0007292 2 0.184
regulation of mapk cascade GO:0043408 262 0.175
regulation of secretion by cell GO:1903530 177 0.171
regulation of camp metabolic process GO:0030814 52 0.165
alcohol metabolic process GO:0006066 114 0.160
organophosphate catabolic process GO:0046434 430 0.160
guanosine containing compound metabolic process GO:1901068 244 0.152
compound eye development GO:0048749 1 0.152
regulation of transferase activity GO:0051338 355 0.149
oogenesis GO:0048477 2 0.149
regulation of protein serine threonine kinase activity GO:0071900 179 0.145
positive regulation of protein kinase activity GO:0045860 190 0.141
exocytosis GO:0006887 71 0.138
growth GO:0040007 202 0.137
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.133
regulation of camp biosynthetic process GO:0030817 45 0.127
cyclic nucleotide biosynthetic process GO:0009190 61 0.127
ras protein signal transduction GO:0007265 73 0.127
purine ribonucleotide biosynthetic process GO:0009152 79 0.127
cell development GO:0048468 328 0.123
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.120
nucleotide biosynthetic process GO:0009165 109 0.119
small gtpase mediated signal transduction GO:0007264 78 0.117
phospholipid metabolic process GO:0006644 99 0.112
anatomical structure formation involved in morphogenesis GO:0048646 284 0.111
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.110
gtp metabolic process GO:0046039 239 0.109
establishment or maintenance of cell polarity GO:0007163 31 0.108
cellular protein complex assembly GO:0043623 188 0.107
guanosine containing compound catabolic process GO:1901069 239 0.106
positive regulation of protein phosphorylation GO:0001934 313 0.106
regulation of vesicle mediated transport GO:0060627 130 0.105
regulation of protein kinase activity GO:0045859 289 0.101
g protein coupled receptor signaling pathway GO:0007186 207 0.101
ribonucleotide biosynthetic process GO:0009260 81 0.097
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.097
regulation of adenylate cyclase activity GO:0045761 17 0.096
positive regulation of cell proliferation GO:0008284 301 0.096
positive regulation of nucleotide catabolic process GO:0030813 185 0.096
nucleoside triphosphate metabolic process GO:0009141 422 0.095
regulation of map kinase activity GO:0043405 108 0.094
lipid metabolic process GO:0006629 381 0.094
amine metabolic process GO:0009308 44 0.093
positive regulation of camp metabolic process GO:0030816 41 0.092
cyclic purine nucleotide metabolic process GO:0052652 60 0.092
actin filament based process GO:0030029 224 0.091
regulation of purine nucleotide metabolic process GO:1900542 264 0.090
signal transduction by phosphorylation GO:0023014 297 0.089
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.088
glycerolipid biosynthetic process GO:0045017 51 0.088
cytoplasmic transport GO:0016482 379 0.088
purine ribonucleoside metabolic process GO:0046128 437 0.088
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.088
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.085
purine nucleoside triphosphate catabolic process GO:0009146 392 0.084
positive regulation of developmental process GO:0051094 314 0.083
positive regulation of kinase activity GO:0033674 204 0.083
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.081
regulation of cell projection organization GO:0031344 107 0.078
regulation of secretion GO:0051046 194 0.078
mapk cascade GO:0000165 288 0.076
mitotic cell cycle GO:0000278 326 0.076
nucleoside phosphate biosynthetic process GO:1901293 109 0.075
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.073
regulation of cellular component biogenesis GO:0044087 281 0.073
positive regulation of transferase activity GO:0051347 227 0.072
single organism cellular localization GO:1902580 332 0.072
organic hydroxy compound metabolic process GO:1901615 147 0.072
glycerolipid metabolic process GO:0046486 107 0.072
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.072
oocyte differentiation GO:0009994 2 0.071
regulation of gtp catabolic process GO:0033124 180 0.071
dephosphorylation GO:0016311 209 0.071
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.070
phospholipid biosynthetic process GO:0008654 44 0.068
cytokinesis GO:0000910 96 0.068
cellular macromolecular complex assembly GO:0034622 324 0.068
single organism membrane organization GO:0044802 268 0.068
ribonucleoside triphosphate catabolic process GO:0009203 391 0.068
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.067
rho protein signal transduction GO:0007266 26 0.067
protein localization to organelle GO:0033365 280 0.066
regulation of protein localization GO:0032880 296 0.065
purine ribonucleotide catabolic process GO:0009154 404 0.065
purine containing compound catabolic process GO:0072523 411 0.063
nuclear division GO:0000280 128 0.063
ribonucleoside triphosphate metabolic process GO:0009199 412 0.062
negative regulation of phosphate metabolic process GO:0045936 267 0.062
ribonucleoside catabolic process GO:0042454 406 0.062
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.061
embryo development GO:0009790 123 0.060
purine nucleotide catabolic process GO:0006195 405 0.060
cyclic nucleotide metabolic process GO:0009187 82 0.060
intracellular protein transport GO:0006886 270 0.059
phosphatidylinositol metabolic process GO:0046488 53 0.058
ribonucleotide catabolic process GO:0009261 405 0.058
mitotic cell cycle process GO:1903047 286 0.057
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.054
regulation of cellular response to stress GO:0080135 244 0.054
stress activated protein kinase signaling cascade GO:0031098 94 0.054
cellular component morphogenesis GO:0032989 314 0.053
regulation of stress activated mapk cascade GO:0032872 84 0.053
nucleoside phosphate catabolic process GO:1901292 412 0.053
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.053
positive regulation of cellular component organization GO:0051130 376 0.052
negative regulation of protein phosphorylation GO:0001933 140 0.051
negative regulation of cellular catabolic process GO:0031330 83 0.050
gtp catabolic process GO:0006184 237 0.050
regulation of nervous system development GO:0051960 88 0.050
purine nucleotide biosynthetic process GO:0006164 84 0.049
regulation of epithelial cell proliferation GO:0050678 113 0.048
negative regulation of catabolic process GO:0009895 104 0.048
epithelial cell proliferation GO:0050673 128 0.048
jnk cascade GO:0007254 80 0.048
nitrogen compound transport GO:0071705 191 0.047
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
regulation of cell cycle GO:0051726 393 0.044
cell division GO:0051301 168 0.044
positive regulation of hydrolase activity GO:0051345 331 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
regulation of mitotic cell cycle GO:0007346 189 0.042
regulation of cell migration GO:0030334 289 0.041
positive regulation of ras gtpase activity GO:0032320 117 0.041
cellular carbohydrate metabolic process GO:0044262 84 0.041
cell cycle phase transition GO:0044770 173 0.040
cellular metal ion homeostasis GO:0006875 146 0.040
glycosyl compound catabolic process GO:1901658 413 0.040
regulation of protein complex assembly GO:0043254 147 0.040
cellular amino acid metabolic process GO:0006520 116 0.039
carbohydrate derivative biosynthetic process GO:1901137 207 0.039
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
positive regulation of cell development GO:0010720 92 0.039
endocytosis GO:0006897 159 0.039
actin cytoskeleton organization GO:0030036 207 0.038
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.038
regulation of actin cytoskeleton organization GO:0032956 116 0.037
posttranscriptional regulation of gene expression GO:0010608 213 0.037
wound healing GO:0042060 115 0.037
cellular divalent inorganic cation homeostasis GO:0072503 128 0.036
reproductive process GO:0022414 106 0.036
regulation of anatomical structure morphogenesis GO:0022603 286 0.036
cell projection assembly GO:0030031 126 0.036
lipid biosynthetic process GO:0008610 177 0.036
nucleoside catabolic process GO:0009164 408 0.036
positive regulation of catabolic process GO:0009896 310 0.036
epithelium development GO:0060429 227 0.035
cilium morphogenesis GO:0060271 75 0.035
negative regulation of catalytic activity GO:0043086 335 0.034
negative regulation of programmed cell death GO:0043069 321 0.034
protein targeting GO:0006605 187 0.034
regulation of nucleoside metabolic process GO:0009118 209 0.034
positive regulation of gtp catabolic process GO:0033126 166 0.034
response to abiotic stimulus GO:0009628 336 0.033
vesicle mediated transport GO:0016192 371 0.033
protein catabolic process GO:0030163 325 0.033
multicellular organismal aging GO:0010259 3 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
regulation of cyclase activity GO:0031279 19 0.033
plasma membrane organization GO:0007009 115 0.033
cellular amine metabolic process GO:0044106 41 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.032
negative regulation of transferase activity GO:0051348 124 0.032
purine containing compound biosynthetic process GO:0072522 88 0.031
protein import GO:0017038 130 0.031
chemical homeostasis GO:0048878 306 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.030
regulation of autophagy GO:0010506 52 0.030
regulation of ras gtpase activity GO:0032318 128 0.030
positive regulation of cellular component biogenesis GO:0044089 158 0.030
regulation of cell motility GO:2000145 299 0.030
positive regulation of cell migration GO:0030335 172 0.030
peripheral nervous system development GO:0007422 2 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
organonitrogen compound biosynthetic process GO:1901566 200 0.029
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
cell morphogenesis GO:0000902 296 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
mitotic cell cycle checkpoint GO:0007093 68 0.028
macromolecular complex disassembly GO:0032984 60 0.028
cation transport GO:0006812 331 0.028
regulation of locomotion GO:0040012 329 0.028
positive regulation of cell projection organization GO:0031346 64 0.027
regulation of nucleotide biosynthetic process GO:0030808 50 0.027
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
regulation of dna metabolic process GO:0051052 153 0.027
blood vessel development GO:0001568 172 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
glycerophospholipid metabolic process GO:0006650 84 0.026
regulation of intracellular transport GO:0032386 195 0.026
cell projection organization GO:0030030 252 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
cell growth GO:0016049 160 0.025
regulation of wound healing GO:0061041 56 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.025
cellular protein catabolic process GO:0044257 261 0.025
stress activated mapk cascade GO:0051403 93 0.025
response to wounding GO:0009611 168 0.024
negative regulation of protein modification process GO:0031400 200 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
nucleotide catabolic process GO:0009166 408 0.024
positive regulation of locomotion GO:0040017 186 0.024
positive regulation of cyclase activity GO:0031281 13 0.024
nuclear transport GO:0051169 179 0.024
oocyte development GO:0048599 1 0.024
erk1 and erk2 cascade GO:0070371 104 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
establishment of organelle localization GO:0051656 59 0.023
neuron development GO:0048666 113 0.023
endosomal transport GO:0016197 129 0.023
membrane raft localization GO:0051665 1 0.023
immune response GO:0006955 307 0.023
membrane organization GO:0061024 292 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
protein import into nucleus GO:0006606 104 0.022
positive regulation of organelle organization GO:0010638 195 0.022
replicative cell aging GO:0001302 3 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.021
organelle localization GO:0051640 84 0.021
positive regulation of mapk cascade GO:0043410 190 0.021
positive regulation of rac gtpase activity GO:0032855 31 0.021
negative regulation of cell cycle GO:0045786 193 0.021
regulation of cellular component movement GO:0051270 334 0.021
regulation of cellular component size GO:0032535 82 0.021
negative regulation of cell cycle phase transition GO:1901988 89 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
glycerophospholipid biosynthetic process GO:0046474 40 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
regulation of actin filament based process GO:0032970 141 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
cellular response to nutrient levels GO:0031669 69 0.020
regulation of anatomical structure size GO:0090066 101 0.020
cell adhesion GO:0007155 325 0.020
neurogenesis GO:0022008 169 0.020
regulation of dna replication GO:0006275 68 0.020
positive regulation of nervous system development GO:0051962 54 0.019
circulatory system development GO:0072359 262 0.019
regulation of body fluid levels GO:0050878 99 0.019
response to starvation GO:0042594 59 0.019
neuromuscular junction development GO:0007528 3 0.019
regulation of cell development GO:0060284 161 0.019
vasculature development GO:0001944 181 0.019
molting cycle GO:0042303 28 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
developmental growth GO:0048589 48 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
signal release GO:0023061 70 0.019
positive regulation of cell death GO:0010942 263 0.018
positive regulation of dna replication GO:0045740 35 0.018
determination of adult lifespan GO:0008340 2 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
spermatid development GO:0007286 4 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
meiosis i GO:0007127 4 0.018
positive regulation of angiogenesis GO:0045766 51 0.018
regulation of gtpase activity GO:0043087 180 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
locomotory behavior GO:0007626 1 0.017
Mouse
regulation of intracellular protein transport GO:0033157 123 0.017
cellular response to extracellular stimulus GO:0031668 72 0.017
angiogenesis GO:0001525 147 0.017
maintenance of location GO:0051235 112 0.017
cell cell signaling GO:0007267 155 0.017
organelle fission GO:0048285 149 0.017
regulation of protein stability GO:0031647 87 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
positive regulation of jnk cascade GO:0046330 52 0.017
blood vessel morphogenesis GO:0048514 162 0.017
regulation of cell cycle process GO:0010564 266 0.017
cellular ion homeostasis GO:0006873 168 0.017
regulation of response to external stimulus GO:0032101 222 0.017
establishment of blood brain barrier GO:0060856 1 0.017
establishment of protein localization to organelle GO:0072594 172 0.016
organ morphogenesis GO:0009887 147 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
central nervous system development GO:0007417 123 0.016
response to biotic stimulus GO:0009607 276 0.016
vacuolar transport GO:0007034 34 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
protein targeting to nucleus GO:0044744 104 0.016
establishment of nucleus localization GO:0040023 1 0.016
organelle assembly GO:0070925 176 0.016
microtubule based process GO:0007017 210 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
regulation of cell projection assembly GO:0060491 47 0.016
autophagy GO:0006914 88 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
regulation of rho gtpase activity GO:0032319 66 0.015
spermatid differentiation GO:0048515 4 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of neuron differentiation GO:0045664 70 0.015
protein maturation GO:0051604 233 0.015
lipid transport GO:0006869 90 0.015
protein oligomerization GO:0051259 173 0.015
regulation of vasculature development GO:1901342 97 0.015
cellular response to starvation GO:0009267 58 0.015
vesicle organization GO:0016050 62 0.015
negative regulation of ras gtpase activity GO:0034261 6 0.014
apoptotic signaling pathway GO:0097190 268 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
response to nutrient levels GO:0031667 81 0.014
sequestering of metal ion GO:0051238 24 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
positive regulation of cell motility GO:2000147 177 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
generation of neurons GO:0048699 152 0.014
cell cell junction organization GO:0045216 69 0.014
positive regulation of gtpase activity GO:0043547 166 0.013
regulation of angiogenesis GO:0045765 92 0.013
macroautophagy GO:0016236 39 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
negative regulation of kinase activity GO:0033673 106 0.013
jak stat cascade GO:0007259 46 0.013
negative regulation of autophagy GO:0010507 14 0.013
negative regulation of response to external stimulus GO:0032102 83 0.013
nervous system development GO:0007399 293 0.013
protein localization to membrane GO:0072657 160 0.013
dna replication GO:0006260 116 0.013
cellular response to external stimulus GO:0071496 111 0.013
positive regulation of neurogenesis GO:0050769 49 0.013
actin cytoskeleton reorganization GO:0031532 37 0.013
lysosomal transport GO:0007041 33 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of jnk cascade GO:0046328 73 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
cell cycle checkpoint GO:0000075 117 0.012
reproduction GO:0000003 63 0.012
tor signaling GO:0031929 39 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
regulation of filopodium assembly GO:0051489 13 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 6 0.012
single organism nuclear import GO:1902593 104 0.012
cardiovascular system development GO:0072358 262 0.012
positive regulation of secretion GO:0051047 116 0.012
cell part morphogenesis GO:0032990 137 0.012
metal ion transport GO:0030001 272 0.012
regulation of macroautophagy GO:0016241 19 0.012
regulation of neuron projection development GO:0010975 57 0.012
cellular chemical homeostasis GO:0055082 180 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
biological adhesion GO:0022610 331 0.011
negative regulation of protein complex assembly GO:0031333 43 0.011
phosphatidylinositol biosynthetic process GO:0006661 25 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
developmental process involved in reproduction GO:0003006 66 0.011
protein localization to plasma membrane GO:0072659 93 0.011
positive regulation of neuron differentiation GO:0045666 40 0.011
single organism reproductive process GO:0044702 98 0.011
cell junction organization GO:0034330 79 0.011
cilium organization GO:0044782 68 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
positive regulation of transcription by galactose GO:0000411 1 0.011
cell activation GO:0001775 213 0.011
neurological system process GO:0050877 163 0.011
Mouse
cellular homeostasis GO:0019725 196 0.011
behavior GO:0007610 112 0.011
Mouse
ruffle organization GO:0031529 18 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
maintenance of cell polarity GO:0030011 2 0.011
negative regulation of macroautophagy GO:0016242 4 0.011
system process GO:0003008 349 0.011
Mouse
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
regulation of protein targeting GO:1903533 91 0.011
regulation of peptide hormone secretion GO:0090276 41 0.011
protein polymerization GO:0051258 71 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
regulation of proteolysis GO:0030162 293 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of erk1 and erk2 cascade GO:0070372 99 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
gonad development GO:0008406 34 0.010

GMFB disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.121
cancer DOID:162 167 0.070
organ system cancer DOID:0050686 164 0.067
endocrine gland cancer DOID:170 26 0.020
retinal disease DOID:5679 118 0.010
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010
nervous system disease DOID:863 431 0.010
eye disease DOID:5614 149 0.010
central nervous system disease DOID:331 186 0.010
brain disease DOID:936 73 0.010