|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.791
|
Human Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.562
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.551
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.542
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.496
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.494
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.480
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.470
|
Human |
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.463
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.455
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.441
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.441
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.430
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.408
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.387
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.384
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.372
|
Human |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.370
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.363
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.358
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.343
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.338
|
Human Worm Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.310
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.308
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.306
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.292
|
Worm |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.291
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.278
|
Worm Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.272
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.267
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.257
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.249
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.246
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.236
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.234
|
Fly |
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.222
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.221
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.211
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.208
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.205
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.203
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.201
|
Human |
|
|
exocytosis
|
GO:0006887 |
71 |
0.190
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.182
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.182
|
Human Fly |
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.180
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.174
|
Human |
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.170
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.163
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.159
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.154
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.153
|
Human |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.152
|
Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.152
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.149
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.148
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.146
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.146
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.143
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.137
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.134
|
|
|
|
growth
|
GO:0040007 |
202 |
0.134
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.128
|
Fly |
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.126
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.123
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.123
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.123
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.121
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.121
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.120
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.120
|
Worm Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.119
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.119
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.118
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.116
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.115
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.115
|
Human |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.115
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.115
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.114
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.113
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.112
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.111
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.107
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.107
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.106
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.105
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.104
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.104
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.101
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.098
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.098
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.098
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.097
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.097
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.096
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.096
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.096
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.096
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.096
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.095
|
Worm |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.095
|
Human |
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.095
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.094
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.094
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.094
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.090
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.090
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.090
|
Human |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.089
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.089
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.088
|
Worm |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.087
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.085
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.084
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.084
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.083
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.081
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.081
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.079
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.078
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.077
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.077
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.076
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.074
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.074
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.074
|
Human |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.073
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.071
|
Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.070
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.070
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.070
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.070
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.069
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.067
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.067
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.066
|
Human |
|
|
actin filament capping
|
GO:0051693 |
4 |
0.066
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.066
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.064
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.064
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.062
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.062
|
Human |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.061
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.061
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.061
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.060
|
Human |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.060
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.060
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.059
|
Human |
|
|
reproduction
|
GO:0000003 |
63 |
0.058
|
Worm |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.058
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.058
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.057
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.057
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.057
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.056
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.056
|
Worm Fly |
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.056
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.055
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.054
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.053
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.053
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.052
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.052
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.052
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.052
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.052
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.051
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.051
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.051
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.051
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.051
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.050
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.050
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.050
|
Human Fly |
|
|
negative regulation of skeletal muscle tissue development
|
GO:0048642 |
2 |
0.047
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.046
|
Human |
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.046
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.045
|
Human |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.045
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.045
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.043
|
Fly |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.043
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.042
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.041
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.041
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.041
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.041
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.041
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.041
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.041
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.041
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.040
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.040
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.040
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.040
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.038
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.038
|
Worm Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.038
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.038
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.037
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.037
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.037
|
Human |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.037
|
Human |
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.036
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.036
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.035
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.035
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.035
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.035
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.035
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.034
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.034
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.034
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.033
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.033
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.033
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.033
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.033
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.033
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.033
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.033
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.033
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.032
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.032
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.031
|
|
|
|
actin filament reorganization
|
GO:0090527 |
1 |
0.031
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.031
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.031
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.031
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.031
|
Human |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.031
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.030
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.030
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.030
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.030
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.030
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.029
|
Human Fly |
|
|
system process
|
GO:0003008 |
349 |
0.029
|
Human Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.029
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.029
|
Fly |
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.029
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.028
|
Human |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.028
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.028
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.027
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.027
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.027
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.027
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.027
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.027
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.027
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.027
|
Human |
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.027
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.026
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.026
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.026
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.026
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.026
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.026
|
Human |
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.026
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.026
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.026
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.026
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.026
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.026
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.026
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.025
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.024
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.024
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.024
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.024
|
Human |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.024
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.024
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.024
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.024
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.023
|
Fly |
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.023
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.023
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.023
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.023
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.023
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.023
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.023
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.023
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.023
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.022
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.022
|
Worm Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.022
|
|
|
|
golgi vesicle fusion to target membrane
|
GO:0048210 |
2 |
0.022
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.022
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.022
|
Human |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.022
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.022
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.022
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.021
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.021
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.021
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.021
|
|
|
|
ruffle organization
|
GO:0031529 |
18 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.021
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.021
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.020
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.020
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.020
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.020
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.020
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.020
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.020
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.020
|
Fly |
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.020
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.020
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.019
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.019
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.019
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.019
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.019
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.019
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.019
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.019
|
Human |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.018
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.018
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.018
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.018
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.018
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.018
|
Human |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.018
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.018
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.018
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.018
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.018
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.018
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.018
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.017
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.017
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.017
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.017
|
|
|
|
head development
|
GO:0060322 |
108 |
0.017
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.017
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.017
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.017
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.017
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.017
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.017
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.017
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
|
localization within membrane
|
GO:0051668 |
14 |
0.017
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.016
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.016
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.016
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.016
|
Human |
|
|
developmental maturation
|
GO:0021700 |
28 |
0.016
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.016
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.016
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.016
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.016
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.016
|
Human |
|
|
negative regulation of arp2 3 complex mediated actin nucleation
|
GO:0034316 |
1 |
0.016
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.016
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.015
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.015
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.015
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.015
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.015
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.015
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.015
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.015
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.015
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.015
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.015
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.015
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.014
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.014
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.014
|
Worm |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.014
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.014
|
Human |
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.014
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.014
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.014
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.014
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.014
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.014
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.014
|
Human |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.014
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.014
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
5 |
0.014
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.014
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.014
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.014
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.014
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.013
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.013
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.013
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.013
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.013
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.013
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.013
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.013
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.013
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.013
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.013
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.013
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.013
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.013
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.013
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.013
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.013
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.013
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.013
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.013
|
Human |
|
|
actin nucleation
|
GO:0045010 |
21 |
0.012
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.012
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.012
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.012
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.012
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.012
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.012
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.012
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.012
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.012
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.012
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.012
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.012
|
|
|
|
nucleosome assembly
|
GO:0006334 |
50 |
0.012
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.012
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.012
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.012
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.012
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.012
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.012
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.012
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.012
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.012
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.012
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.012
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.012
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.011
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.011
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.011
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.011
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.011
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.011
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.011
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.011
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.011
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.011
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.011
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.011
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.011
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.011
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.011
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.011
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.011
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.011
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.011
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.011
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.011
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.011
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.011
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.011
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.011
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.011
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.011
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.011
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.010
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.010
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.010
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.010
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.010
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.010
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.010
|
Human |
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.010
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.010
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.010
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.010
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.010
|
Fly |
