|
|
cation transport
|
GO:0006812 |
331 |
0.679
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.629
|
Human |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.430
|
Human |
|
|
dimeric g protein coupled receptor signaling pathway
|
GO:0038042 |
1 |
0.429
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.424
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.401
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.399
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.390
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.383
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.372
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.369
|
|
|
|
system process
|
GO:0003008 |
349 |
0.350
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.332
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.323
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.317
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.314
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.311
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.303
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.302
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.299
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.287
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.276
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.271
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.271
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.269
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.266
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.254
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.237
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.227
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.223
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.223
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.223
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.221
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.217
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.216
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.204
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.201
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.200
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.199
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.192
|
Human |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.189
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.185
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.184
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.183
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.174
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.171
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.170
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.170
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.170
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.168
|
|
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
4 |
0.161
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.155
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.155
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.148
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.148
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.148
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.146
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.143
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.140
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.136
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.130
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.130
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.126
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.123
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.121
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.119
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.117
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.116
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.114
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.112
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.110
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.109
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.108
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.108
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.106
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.106
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.104
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.103
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.100
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.100
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.099
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.096
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.096
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.096
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.095
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.095
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.094
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.093
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.093
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.093
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.091
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.091
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.091
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.089
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.089
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.088
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.087
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.085
|
|
|
|
follicle stimulating hormone secretion
|
GO:0046884 |
3 |
0.084
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.083
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.083
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.082
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.081
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.081
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.080
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.079
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.078
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.078
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.078
|
|
|
|
memory
|
GO:0007613 |
3 |
0.077
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.075
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.074
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.072
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.072
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.072
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.070
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.069
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.069
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.069
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.068
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.068
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.067
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.067
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.067
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.066
|
|
|
|
opioid receptor signaling pathway
|
GO:0038003 |
4 |
0.066
|
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
1 |
0.065
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.064
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.064
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.063
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.063
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.063
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.062
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.062
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.061
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.061
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.061
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.061
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.060
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.060
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.060
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.059
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.059
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.059
|
|
|
|
phospholipase c activating adrenergic receptor signaling pathway
|
GO:0071882 |
1 |
0.059
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.058
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.058
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.057
|
|
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.057
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.057
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.057
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.056
|
|
|
|
adenylate cyclase inhibiting opioid receptor signaling pathway
|
GO:0031635 |
1 |
0.056
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.056
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.055
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.054
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.053
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.053
|
Human |
|
|
positive regulation of acrosome reaction
|
GO:2000344 |
4 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.052
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.052
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.052
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.052
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.051
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.051
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.051
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.051
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.050
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.050
|
Human |
|
|
positive regulation of large conductance calcium activated potassium channel activity
|
GO:1902608 |
2 |
0.050
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.050
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.050
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.050
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.050
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.049
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.049
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.049
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.049
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.049
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.049
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.048
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.048
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.048
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.048
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.047
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.047
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.046
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.045
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.045
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.044
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.044
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.044
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.044
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.044
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.043
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.043
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.043
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.043
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.043
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.042
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.042
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.042
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.042
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.041
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.041
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.041
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.041
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.041
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.041
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.041
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.040
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.040
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.040
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.040
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.040
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.040
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.040
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.040
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.040
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.040
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.039
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.039
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
6 |
0.039
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.038
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.038
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.038
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.038
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
10 |
0.038
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.038
|
|
|
|
mating
|
GO:0007618 |
1 |
0.038
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.037
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.037
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.037
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.037
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.037
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.037
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.037
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.037
|
|
|
|
negative regulation of wnt protein secretion
|
GO:0061358 |
1 |
0.037
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.036
|
|
|
|
cellular response to disaccharide stimulus
|
GO:0071324 |
1 |
0.036
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.036
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.036
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.036
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.036
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
11 |
0.036
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.036
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.036
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.036
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.035
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.035
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.035
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.035
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.035
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.035
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.035
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.035
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.035
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.034
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.034
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.034
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.034
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.034
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.033
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.033
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.033
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.033
|
|
|
|
regulation of large conductance calcium activated potassium channel activity
|
GO:1902606 |
2 |
0.033
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.033
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.033
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.033
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.033
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.033
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.032
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.032
|
|
|
|
positive regulation of glucocorticoid secretion
|
GO:2000851 |
4 |
0.032
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.032
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.032
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.032
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.032
|
|
|
|
luteinizing hormone secretion
|
GO:0032275 |
1 |
0.032
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.032
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.031
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.031
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.031
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.031
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.031
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.031
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.031
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.030
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.030
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.030
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.030
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.030
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.030
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.030
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.029
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.029
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.029
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.029
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.029
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.029
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.029
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.029
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.029
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.029
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.028
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.028
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.028
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.028
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.028
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.028
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.028
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.028
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.028
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.028
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.028
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.028
|
Human |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.028
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.027
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.027
|
|
|
|
cellular response to corticotropin releasing hormone stimulus
|
GO:0071376 |
1 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.027
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.027
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.027
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.027
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.027
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.027
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.027
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.027
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.027
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.026
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.026
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.026
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.026
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.026
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.026
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.026
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.026
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.026
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.026
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.026
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.026
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.026
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.026
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.025
|
|
|
|
micturition
|
GO:0060073 |
3 |
0.025
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.025
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.025
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.025
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.025
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.025
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.025
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.025
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.025
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.025
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.025
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.025
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.025
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.025
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.025
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.025
|
|
|
|
head development
|
GO:0060322 |
108 |
0.025
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.025
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.025
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.024
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
10 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.024
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.024
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.024
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.024
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.024
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.024
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.024
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.024
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.024
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.024
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.024
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.023
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.023
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.023
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.023
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.023
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.023
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.023
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.023
|
|
|
|
regulation of acrosome reaction
|
GO:0060046 |
4 |
0.023
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.023
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.023
|
|
|
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
0.023
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.022
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.022
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.022
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.022
|
|
|
|
cellular response to sucrose stimulus
|
GO:0071329 |
1 |
0.022
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.022
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.022
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.022
|
|
|
|
response to sucrose
|
GO:0009744 |
1 |
0.022
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.022
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.022
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.022
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.022
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.021
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.021
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.021
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.021
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.021
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.021
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.021
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.021
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.021
|
|
|
|
catecholamine secretion
|
GO:0050432 |
1 |
0.021
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.021
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.021
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.021
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.021
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.021
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.020
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.020
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.020
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.020
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.020
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.020
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.020
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.020
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.020
|
Human |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.020
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.020
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.020
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.020
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.020
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.020
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.020
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.020
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.020
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.020
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.020
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.019
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.019
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.019
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
1 |
0.019
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.019
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.019
|
|
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.019
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.019
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.019
|
|
|
|
negative regulation of camp metabolic process
|
GO:0030815 |
9 |
0.019
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.019
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.019
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.019
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.019
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.019
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.019
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.019
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.019
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.019
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.019
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.019
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.019
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.019
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.019
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.019
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.018
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.018
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.018
|
|
