|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.999
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.997
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.996
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.995
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.993
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.992
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.992
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.992
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.987
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.987
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.986
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.985
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.984
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.983
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.982
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.981
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.980
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.979
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.973
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.972
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.972
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.972
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.971
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.971
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.969
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.967
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.966
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.966
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.965
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.961
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.954
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.948
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.947
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.940
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.939
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.938
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.938
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.935
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.927
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.925
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.924
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.922
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.920
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
4 |
0.914
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.911
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.911
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.910
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.897
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.892
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.889
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.884
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.874
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.873
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.872
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.870
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.869
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.868
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.868
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.867
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.864
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.863
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.860
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.858
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.853
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.848
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.844
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.841
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.833
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.830
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.829
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.826
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.824
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.822
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.822
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.810
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.803
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.803
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.802
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.800
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.799
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.797
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.797
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.796
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.796
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.790
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.782
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.781
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.772
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.771
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.752
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.749
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.745
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.739
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.738
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.736
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.725
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.722
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.711
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.709
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.708
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.706
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.705
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.704
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.700
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.700
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.698
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.697
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.696
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.691
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.688
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.687
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.680
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.677
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.669
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.669
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.669
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.649
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.647
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.640
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.640
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.639
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.638
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.637
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.628
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.623
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.622
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.615
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.608
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.603
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.602
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.602
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.602
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.594
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.590
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.585
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.568
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.564
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.555
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.552
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.551
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.549
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.549
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.530
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.530
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.517
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.511
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.508
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.503
|
|
|
|
system process
|
GO:0003008 |
349 |
0.503
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.500
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.500
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.494
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.489
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.489
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.487
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.486
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.485
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.481
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.470
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.462
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.456
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.456
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.456
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.449
|
|
|
|
cell cell recognition
|
GO:0009988 |
4 |
0.446
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.439
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.436
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.434
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.432
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.429
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.422
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.419
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.414
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.414
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.411
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.406
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.404
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.402
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.400
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.398
|
|
|
|
sensory perception of temperature stimulus
|
GO:0050951 |
1 |
0.392
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.390
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.381
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.378
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.372
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.370
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.370
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.368
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.366
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.366
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.363
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.363
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.362
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.358
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.357
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.355
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.349
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.348
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.344
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.336
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.335
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.334
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.327
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.325
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.323
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.322
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.322
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.319
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.318
|
|
|
|
negative regulation of collateral sprouting
|
GO:0048671 |
1 |
0.318
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.317
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.317
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.313
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.311
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.309
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.300
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.297
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.295
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.290
|
|
|
|
positive regulation of rho guanyl nucleotide exchange factor activity
|
GO:2001108 |
1 |
0.289
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.288
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.286
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.284
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.279
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.277
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.267
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.266
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.265
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.265
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.262
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.262
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.254
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.250
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.246
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.245
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.242
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.242
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.239
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.234
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.234
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.234
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.231
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.230
|
|
|
|
optic nerve development
|
GO:0021554 |
2 |
0.228
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.227
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.227
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.224
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.216
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.215
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.215
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.213
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.212
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.211
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.209
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.208
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.207
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.205
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.204
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.200
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.199
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.199
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.198
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.196
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.195
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.194
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.193
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.193
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.191
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.190
|
Mouse |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.189
|
|
|
|
regulation of cdc42 gtpase activity
|
GO:0043088 |
10 |
0.186
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.184
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.184
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.183
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.180
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.180
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.180
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.179
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.179
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.178
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.174
|
|
|
|
regulation of collateral sprouting
|
GO:0048670 |
2 |
0.173
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.173
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.171
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.171
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.170
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.170
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.170
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.166
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.166
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.165
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.163
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.163
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.162
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.162
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.161
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.160
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.158
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.158
|
|
|
|
memory
|
GO:0007613 |
3 |
0.158
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.158
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.157
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.155
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.154
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.154
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.153
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.153
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.151
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.150
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.149
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.149
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.149
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.147
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.147
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.146
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.146
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.146
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.144
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.143
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.143
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.140
|
Mouse |
|
|
positive regulation of hormone secretion
|
GO:0046887 |
25 |
0.140
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.137
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.136
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.135
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.134
|
|
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
0.133
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.130
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.130
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.129
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.129
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.128
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.128
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.125
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.124
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
24 |
0.124
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.123
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.122
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.122
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.121
|
|
|
|
regulation of skeletal muscle cell proliferation
|
GO:0014857 |
1 |
0.121
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.120
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.119
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.116
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.116
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.114
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.113
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.113
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.112
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.111
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.111
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.111
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.110
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.109
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
12 |
0.108
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.108
|
|
|
|
regulation of rho guanyl nucleotide exchange factor activity
|
GO:2001106 |
1 |
0.108
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.107
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.107
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.106
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.106
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.105
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.105
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.104
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.103
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.103
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.102
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.102
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.100
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.100
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.100
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.099
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.099
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.098
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.098
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.097
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.097
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.097
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.097
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.095
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.095
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.094
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.094
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.093
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.093
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.092
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.092
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.092
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.091
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.091
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.090
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.090
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.090
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.090
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.090
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.089
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.089
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.089
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.088
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.088
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.087
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.087
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.086
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.086
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.085
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.085
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.085
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.084
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.084
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.084
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.083
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.083
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.082
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.082
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.081
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.081
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.081
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.081
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.081
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.080
|
|
|
|
growth
|
GO:0040007 |
202 |
0.079
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
14 |
0.079
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.078
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.078
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.078
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.078
|
|
|
|
heparin biosynthetic process
|
GO:0030210 |
1 |
0.078
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.077
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.076
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.076
|
Human |
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.075
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
15 |
0.075
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.075
|
|
|
|
schwann cell development
|
GO:0014044 |
1 |
0.074
|
|
|
|
negative regulation of immature t cell proliferation
|
GO:0033087 |
1 |
0.074
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.074
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.073
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.072
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.072
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.071
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.071
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.070
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.070
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.070
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.069
|
|
|
|
negative regulation of positive chemotaxis
|
GO:0050928 |
1 |
0.069
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.069
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.068
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.068
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.067
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.067
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.067
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.067
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.067
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.067
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.066
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.065
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.065
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.064
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.064
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.063
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.062
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.062
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.062
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.062
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.062
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.062
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.062
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.062
|
|
|
|
mating
|
GO:0007618 |
1 |
0.061
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.061
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.061
|
|
|
|
positive regulation of heterotypic cell cell adhesion
|
GO:0034116 |
8 |
0.060
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.060
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.060
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.060
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.060
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.060
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.060
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.059
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.059
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.059
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.059
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.059
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.058
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.058
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.058
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.057
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.057
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.057
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.057
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.057
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.056
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.056
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.056
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.055
|
|
