Homo sapiens

7 known processes

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

(Aliases: NR2B,hNR3,MGC142180,MGC142178,NMDAR2B)

GRIN2B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ionotropic glutamate receptor signaling pathway GO:0035235 16 1.000
Human Mouse Rat
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 1.000
regulation of neuronal synaptic plasticity GO:0048168 1 1.000
Rat
mating GO:0007618 1 1.000
glutamate receptor signaling pathway GO:0007215 23 1.000
Human Mouse Rat
regulation of relaxation of cardiac muscle GO:1901897 2 1.000
adult locomotory behavior GO:0008344 1 0.998
positive regulation of synaptic transmission GO:0050806 4 0.995
Rat
relaxation of cardiac muscle GO:0055119 5 0.995
inorganic ion transmembrane transport GO:0098660 231 0.994
Mouse
regulation of ion transport GO:0043269 189 0.992
Rat
ion transmembrane transport GO:0034220 338 0.991
Human Mouse Rat
memory GO:0007613 3 0.990
Mouse Rat
regulation of transmembrane transport GO:0034762 139 0.990
regulation of neurotransmitter secretion GO:0046928 3 0.989
cation transmembrane transport GO:0098655 238 0.986
Mouse
startle response GO:0001964 3 0.986
Mouse
membrane hyperpolarization GO:0060081 1 0.984
positive regulation of muscle hypertrophy GO:0014742 6 0.981
neurotransmitter secretion GO:0007269 4 0.978
circadian behavior GO:0048512 2 0.972
inorganic cation transmembrane transport GO:0098662 194 0.972
Mouse
behavior GO:0007610 112 0.969
Mouse Rat
regulation of ion transmembrane transport GO:0034765 132 0.967
cation transport GO:0006812 331 0.965
Mouse
system process GO:0003008 349 0.963
Mouse Rat
synaptic transmission GO:0007268 61 0.961
Mouse Rat
cell cell signaling GO:0007267 155 0.955
Mouse Rat
metal ion transport GO:0030001 272 0.952
Mouse
transmembrane transport GO:0055085 399 0.949
Human Mouse Rat
locomotory behavior GO:0007626 1 0.944
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.942
Mouse
calcium ion transport GO:0006816 147 0.941
Mouse
regulation of muscle system process GO:0090257 53 0.941
regulation of relaxation of muscle GO:1901077 3 0.936
regulation of system process GO:0044057 101 0.920
positive regulation of potassium ion transport GO:0043268 15 0.890
divalent metal ion transport GO:0070838 152 0.888
Mouse
rhythmic behavior GO:0007622 2 0.878
cellular potassium ion transport GO:0071804 60 0.876
regulation of membrane potential GO:0042391 95 0.875
Mouse Rat
sleep GO:0030431 2 0.852
striated muscle cell apoptotic process GO:0010658 3 0.843
sensory perception of pain GO:0019233 4 0.831
Mouse
chemical homeostasis GO:0048878 306 0.831
mitochondrial membrane organization GO:0007006 40 0.830
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.829
regulation of secretion GO:0051046 194 0.825
Rat
potassium ion transport GO:0006813 62 0.816
neuron neuron synaptic transmission GO:0007270 6 0.808
positive regulation of muscle cell apoptotic process GO:0010661 4 0.807
potassium ion transmembrane transport GO:0071805 60 0.804
monovalent inorganic cation transport GO:0015672 128 0.798
neurological system process GO:0050877 163 0.775
Mouse Rat
single organism membrane organization GO:0044802 268 0.759
Rat
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.748
relaxation of muscle GO:0090075 7 0.746
neurotransmitter gated ion channel clustering GO:0072578 1 0.739
apoptotic mitochondrial changes GO:0008637 57 0.724
potassium ion export GO:0071435 9 0.713
positive regulation of ion transport GO:0043270 87 0.706
Rat
mitochondrion organization GO:0007005 156 0.694
regulation of synaptic plasticity GO:0048167 3 0.689
Mouse Rat
neuromuscular process controlling balance GO:0050885 7 0.682
regulation of synaptic transmission GO:0050804 11 0.675
Mouse Rat
positive regulation of calcium ion transport GO:0051928 51 0.674
cardiac muscle cell action potential GO:0086001 23 0.663
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.659
actin filament based movement GO:0030048 17 0.654
regulation of metal ion transport GO:0010959 120 0.653
sodium ion transmembrane transport GO:0035725 59 0.651
cognition GO:0050890 43 0.650
Mouse Rat
regulation of secretion by cell GO:1903530 177 0.650
Rat
positive regulation of programmed cell death GO:0043068 249 0.645
regulation of calcium ion transport GO:0051924 79 0.637
neurotransmitter transport GO:0006836 10 0.624
cardiac muscle cell contraction GO:0086003 4 0.622
negative regulation of sodium ion transport GO:0010766 3 0.610
neuromuscular process GO:0050905 15 0.604
Mouse
long term synaptic potentiation GO:0060291 1 0.604
protein oligomerization GO:0051259 173 0.583
neuromuscular junction development GO:0007528 3 0.579
membrane depolarization GO:0051899 26 0.574
Mouse
regulation of neurotransmitter transport GO:0051588 7 0.568
positive regulation of transport GO:0051050 336 0.563
Rat
signal release GO:0023061 70 0.561
visual learning GO:0008542 1 0.560
negative regulation of transport GO:0051051 176 0.559
circadian sleep wake cycle GO:0042745 2 0.540
positive regulation of cell death GO:0010942 263 0.539
Rat
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.530
growth GO:0040007 202 0.527
response to abiotic stimulus GO:0009628 336 0.522
Mouse Rat
divalent inorganic cation transport GO:0072511 158 0.521
Mouse
action potential GO:0001508 34 0.517
Rat
positive regulation of membrane potential GO:0045838 2 0.505
positive regulation of cardiac muscle hypertrophy GO:0010613 6 0.501
protein localization to synapse GO:0035418 2 0.492
regulation of potassium ion transport GO:0043266 24 0.489
regulation of muscle hypertrophy GO:0014743 10 0.479
circadian sleep wake cycle sleep GO:0050802 2 0.469
vocalization behavior GO:0071625 11 0.463
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.461
sodium ion transport GO:0006814 61 0.453
blood circulation GO:0008015 113 0.423
cardiac muscle hypertrophy GO:0003300 14 0.415
regulation of transmembrane transporter activity GO:0022898 74 0.402
secretion GO:0046903 254 0.395
Rat
regulation of ion transmembrane transporter activity GO:0032412 72 0.381
postsynaptic membrane organization GO:0001941 2 0.370
muscle system process GO:0003012 81 0.367
regulation of neurotransmitter levels GO:0001505 15 0.367
female gamete generation GO:0007292 2 0.363
cell type specific apoptotic process GO:0097285 125 0.358
positive regulation of apoptotic process GO:0043065 246 0.346
regulation of sodium ion transmembrane transport GO:1902305 23 0.344
regulation of cardiac muscle hypertrophy GO:0010611 10 0.342
regulation of membrane permeability GO:0090559 25 0.334
negative regulation of receptor mediated endocytosis GO:0048261 6 0.331
spinal cord development GO:0021510 4 0.329
cell projection organization GO:0030030 252 0.318
muscle contraction GO:0006936 73 0.318
cation homeostasis GO:0055080 189 0.314
response to light stimulus GO:0009416 87 0.307
negative regulation of sodium ion transmembrane transport GO:1902306 2 0.302
regulation of growth GO:0040008 165 0.297
regulation of cardiac muscle cell contraction GO:0086004 23 0.294
developmental growth GO:0048589 48 0.293
nervous system development GO:0007399 293 0.291
Rat
single organism behavior GO:0044708 28 0.288
Mouse Rat
response to radiation GO:0009314 151 0.273
regulation of sensory perception GO:0051931 3 0.266
regulation of circadian sleep wake cycle GO:0042749 2 0.265
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.262
neuron development GO:0048666 113 0.261
peptidyl threonine phosphorylation GO:0018107 41 0.256
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.253
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 0.252
mitochondrial transport GO:0006839 60 0.252
regulation of cell cycle process GO:0010564 266 0.250
segmentation GO:0035282 4 0.250
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 4 0.250
regulation of muscle contraction GO:0006937 45 0.249
ion homeostasis GO:0050801 230 0.247
calcium ion transmembrane transport GO:0070588 76 0.245
Mouse
cellular component morphogenesis GO:0032989 314 0.242
striated muscle hypertrophy GO:0014897 14 0.242
synaptic transmission cholinergic GO:0007271 2 0.238
actin mediated cell contraction GO:0070252 12 0.237
directional locomotion GO:0033058 1 0.237
regulation of purine nucleotide metabolic process GO:1900542 264 0.232
muscle hypertrophy GO:0014896 14 0.229
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.227
regulation of cellular component biogenesis GO:0044087 281 0.224
long term memory GO:0007616 2 0.219
Rat
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.217
cardiac muscle cell apoptotic process GO:0010659 3 0.216
cardiac conduction GO:0061337 23 0.210
regulation of behavior GO:0050795 82 0.207
regulation of nervous system development GO:0051960 88 0.207
rhythmic process GO:0048511 31 0.207
Rat
muscle cell apoptotic process GO:0010657 11 0.205
regulation of cell cycle GO:0051726 393 0.201
response to alcohol GO:0097305 64 0.198
response to nutrient levels GO:0031667 81 0.196
Rat
regulation of protein catabolic process GO:0042176 155 0.195
cell cycle g1 s phase transition GO:0044843 80 0.195
cell cycle phase transition GO:0044770 173 0.193
generation of neurons GO:0048699 152 0.190
positive regulation of striated muscle cell apoptotic process GO:0010663 1 0.187
mapk cascade GO:0000165 288 0.186
Rat
membrane repolarization GO:0086009 23 0.186
protein autophosphorylation GO:0046777 123 0.181
regulation of postsynaptic membrane potential GO:0060078 1 0.179
Mouse
potassium ion import GO:0010107 9 0.177
mitotic cell cycle process GO:1903047 286 0.175
secretion by cell GO:0032940 226 0.174
Rat
regulation of sodium ion transport GO:0002028 24 0.173
cellular ketone metabolic process GO:0042180 80 0.173
cell projection assembly GO:0030031 126 0.171
cerebral cortex development GO:0021987 10 0.171
Rat
regulation of cellular amine metabolic process GO:0033238 11 0.169
regulation of ion homeostasis GO:2000021 73 0.165
mitotic cell cycle phase transition GO:0044772 162 0.163
peptidyl threonine modification GO:0018210 45 0.162
regulation of striated muscle cell apoptotic process GO:0010662 3 0.161
cellular divalent inorganic cation homeostasis GO:0072503 128 0.160
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.159
organelle fission GO:0048285 149 0.158
presynaptic membrane organization GO:0097090 3 0.155
multicellular organismal response to stress GO:0033555 1 0.155
Mouse Rat
cell fate commitment involved in pattern specification GO:0060581 1 0.152
regulation of homeostatic process GO:0032844 121 0.150
negative regulation of ion transmembrane transport GO:0034766 26 0.148
oocyte differentiation GO:0009994 2 0.148
cellular response to oxygen containing compound GO:1901701 276 0.147
Rat
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.144
metal ion homeostasis GO:0055065 169 0.142
regulation of actin filament based movement GO:1903115 24 0.142
regulation of map kinase activity GO:0043405 108 0.141
regulation of neuron differentiation GO:0045664 70 0.140
dendritic spine organization GO:0097061 4 0.137
anterior posterior axis specification embryo GO:0008595 2 0.136
cardiac muscle contraction GO:0060048 34 0.135
taxis GO:0042330 157 0.135
negative regulation of catabolic process GO:0009895 104 0.134
membrane organization GO:0061024 292 0.133
Rat
cellular response to organic cyclic compound GO:0071407 127 0.133
Rat
heart contraction GO:0060047 62 0.132
regulation of synapse structure and activity GO:0050803 7 0.132
regulation of mitochondrial membrane permeability GO:0046902 25 0.131
protein catabolic process GO:0030163 325 0.131
positive regulation of cardiac muscle cell apoptotic process GO:0010666 1 0.126
protein tetramerization GO:0051262 47 0.125
mitotic nuclear division GO:0007067 119 0.125
presynaptic membrane assembly GO:0097105 1 0.125
adult behavior GO:0030534 18 0.124
hormone transport GO:0009914 68 0.121
regulation of actin filament based process GO:0032970 141 0.120
regulation of heart contraction GO:0008016 50 0.120
positive regulation of gtp catabolic process GO:0033126 166 0.119
cellular calcium ion homeostasis GO:0006874 117 0.119
negative regulation of neurological system process GO:0031645 2 0.119
striated muscle contraction GO:0006941 52 0.118
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.118
learning GO:0007612 11 0.117
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.116
cell development GO:0048468 328 0.116
nucleoside phosphate biosynthetic process GO:1901293 109 0.115
adaptation of signaling pathway GO:0023058 7 0.114
anterior posterior axis specification GO:0009948 2 0.113
regulation of protein serine threonine kinase activity GO:0071900 179 0.112
single organism cellular localization GO:1902580 332 0.112
Rat
detection of stimulus GO:0051606 85 0.111
Mouse
g protein coupled receptor signaling pathway GO:0007186 207 0.111
negative regulation of protein metabolic process GO:0051248 391 0.110
purine containing compound catabolic process GO:0072523 411 0.110
g1 s transition of mitotic cell cycle GO:0000082 78 0.110
positive regulation of protein kinase activity GO:0045860 190 0.110
positive regulation of nucleotide metabolic process GO:0045981 230 0.109
head development GO:0060322 108 0.109
Rat
neuron projection development GO:0031175 106 0.108
regulation of membrane repolarization GO:0060306 16 0.107
regulation of cell projection organization GO:0031344 107 0.107
cellular lipid metabolic process GO:0044255 303 0.107
response to nitrogen compound GO:1901698 184 0.106
Rat
single organism cell adhesion GO:0098602 179 0.106
peptidyl serine phosphorylation GO:0018105 101 0.105
negative regulation of apoptotic process GO:0043066 316 0.105
cellular response to hormone stimulus GO:0032870 125 0.102
post embryonic development GO:0009791 2 0.101
phospholipase c activating adrenergic receptor signaling pathway GO:0071882 1 0.101
positive regulation of map kinase activity GO:0043406 80 0.101
nucleoside triphosphate catabolic process GO:0009143 394 0.101
circadian sleep wake cycle process GO:0022410 2 0.101
purine ribonucleoside catabolic process GO:0046130 398 0.100
cell projection morphogenesis GO:0048858 129 0.100
mitotic cell cycle GO:0000278 326 0.100
negative regulation of secretion GO:0051048 58 0.099
regulation of neuron projection development GO:0010975 57 0.099
peptidyl serine modification GO:0018209 106 0.098
negative regulation of cell death GO:0060548 345 0.097
positive regulation of phosphorylation GO:0042327 394 0.097
regulation of cellular response to stress GO:0080135 244 0.096
positive regulation of cellular component organization GO:0051130 376 0.096
regulation of heart rate GO:0002027 38 0.093
regulation of protein localization GO:0032880 296 0.093
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.092
purine ribonucleoside metabolic process GO:0046128 437 0.091
regulation of peptide hormone secretion GO:0090276 41 0.090
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.090
positive regulation of phosphatidylinositol biosynthetic process GO:0010513 3 0.090
nucleotide biosynthetic process GO:0009165 109 0.089
negative regulation of phosphorus metabolic process GO:0010563 267 0.088
tripartite regional subdivision GO:0007351 2 0.087
cellular response to nitrogen compound GO:1901699 144 0.087
Rat
regulation of synapse assembly GO:0051963 5 0.087
muscle adaptation GO:0043500 12 0.086
regulation of meiotic cell cycle GO:0051445 4 0.085
receptor localization to synapse GO:0097120 1 0.084
negative regulation of phosphatase activity GO:0010923 61 0.084
blastoderm segmentation GO:0007350 2 0.084
organic hydroxy compound metabolic process GO:1901615 147 0.083
endomembrane system organization GO:0010256 196 0.082
cellular amino acid metabolic process GO:0006520 116 0.081
ras protein signal transduction GO:0007265 73 0.081
indole containing compound metabolic process GO:0042430 4 0.080
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.080
brain development GO:0007420 97 0.079
Rat
response to organic cyclic compound GO:0014070 204 0.079
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.079
oogenesis GO:0048477 2 0.079
actin filament organization GO:0007015 128 0.078
regulation of cell projection assembly GO:0060491 47 0.078
positive regulation of cellular amine metabolic process GO:0033240 7 0.078
regulation of purine nucleotide catabolic process GO:0033121 205 0.078
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.077
regulation of membrane depolarization GO:0003254 19 0.077
neuron differentiation GO:0030182 138 0.076
establishment of protein localization to membrane GO:0090150 121 0.076
regulation of establishment of protein localization GO:0070201 242 0.076
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.075
reproductive process GO:0022414 106 0.075
cellular amine metabolic process GO:0044106 41 0.075
negative regulation of transporter activity GO:0032410 25 0.075
jnk cascade GO:0007254 80 0.074
cellular response to organonitrogen compound GO:0071417 124 0.073
Rat
synapse organization GO:0050808 14 0.072
protein ubiquitination GO:0016567 314 0.072
purine ribonucleotide catabolic process GO:0009154 404 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
single organism carbohydrate metabolic process GO:0044723 193 0.071
negative regulation of phosphate metabolic process GO:0045936 267 0.071
positive regulation of mapk cascade GO:0043410 190 0.071
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.071
nuclear division GO:0000280 128 0.070
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 1 0.070
endothelial cell proliferation GO:0001935 65 0.069
ribonucleotide catabolic process GO:0009261 405 0.069
oocyte development GO:0048599 1 0.069
purine nucleoside triphosphate metabolic process GO:0009144 412 0.069
response to organonitrogen compound GO:0010243 156 0.068
Rat
visual behavior GO:0007632 2 0.068
regulation of cellular amino acid metabolic process GO:0006521 6 0.068
carbohydrate metabolic process GO:0005975 207 0.068
cyclic nucleotide metabolic process GO:0009187 82 0.068
apoptotic signaling pathway GO:0097190 268 0.068
positive regulation of protein catabolic process GO:0045732 75 0.067
response to extracellular stimulus GO:0009991 85 0.067
Rat
positive regulation of developmental process GO:0051094 314 0.066
multi organism reproductive process GO:0044703 54 0.066
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.066
developmental maturation GO:0021700 28 0.066
purine nucleoside catabolic process GO:0006152 398 0.065
cellular chemical homeostasis GO:0055082 180 0.065
regulation of kinase activity GO:0043549 314 0.065
regulation of mapk cascade GO:0043408 262 0.064
Rat
cell communication involved in cardiac conduction GO:0086065 18 0.064
cell morphogenesis involved in differentiation GO:0000904 144 0.064
signal transduction by phosphorylation GO:0023014 297 0.064
Rat
regulation of filopodium assembly GO:0051489 13 0.064
cellular metal ion homeostasis GO:0006875 146 0.063
serotonin receptor signaling pathway GO:0007210 11 0.063
regulation of receptor activity GO:0010469 47 0.062
divalent inorganic cation homeostasis GO:0072507 136 0.062
regulation of cardiac muscle contraction GO:0055117 33 0.061
response to drug GO:0042493 81 0.061
single organismal cell cell adhesion GO:0016337 148 0.061
intracellular protein transport GO:0006886 270 0.061
regeneration GO:0031099 4 0.060
regulation of receptor mediated endocytosis GO:0048259 32 0.060
regulation of cell migration GO:0030334 289 0.060
regulation of protein kinase activity GO:0045859 289 0.060
hippocampus development GO:0021766 1 0.059
Rat
regulation of multi organism process GO:0043900 157 0.058
positive regulation of cellular catabolic process GO:0031331 284 0.058
response to hormone GO:0009725 175 0.057
Rat
reactive nitrogen species metabolic process GO:2001057 3 0.057
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.057
biological adhesion GO:0022610 331 0.057
protein modification by small protein conjugation GO:0032446 342 0.056
regulation of striated muscle contraction GO:0006942 37 0.056
anatomical structure homeostasis GO:0060249 100 0.055
negative regulation of transmembrane transport GO:0034763 29 0.054
positive regulation of transferase activity GO:0051347 227 0.054
regulation of proteasomal protein catabolic process GO:0061136 87 0.053
regulation of dephosphorylation GO:0035303 96 0.053
enzyme linked receptor protein signaling pathway GO:0007167 303 0.053
glycosyl compound catabolic process GO:1901658 413 0.053
central nervous system development GO:0007417 123 0.052
Rat
atrial cardiac muscle cell to av node cell communication GO:0086066 6 0.052
protein localization to membrane GO:0072657 160 0.052
Rat
amine metabolic process GO:0009308 44 0.052
calcium ion homeostasis GO:0055074 122 0.052
epithelial cell proliferation GO:0050673 128 0.051
regulation of autophagy GO:0010506 52 0.051
cell growth GO:0016049 160 0.051
positive regulation of adenylate cyclase activity GO:0045762 12 0.051
forebrain neuron differentiation GO:0021879 3 0.051
regulation of nucleotide metabolic process GO:0006140 269 0.050
positive regulation of proteolysis GO:0045862 142 0.050
positive regulation of dendritic spine development GO:0060999 2 0.050
positive regulation of meiotic cell cycle GO:0051446 2 0.050
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.050
stress activated protein kinase signaling cascade GO:0031098 94 0.049
organophosphate catabolic process GO:0046434 430 0.049
single organism reproductive process GO:0044702 98 0.049
response to lipid GO:0033993 206 0.049
Rat
regulation of cellular component movement GO:0051270 334 0.048
regulation of phosphatase activity GO:0010921 81 0.048
positive regulation of wound healing GO:0090303 20 0.048
positive regulation of nucleoside metabolic process GO:0045979 186 0.047
tissue morphogenesis GO:0048729 96 0.047
detection of abiotic stimulus GO:0009582 15 0.047
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.047
proteasomal protein catabolic process GO:0010498 176 0.047
purine nucleoside triphosphate catabolic process GO:0009146 392 0.047
positive regulation of cellular component movement GO:0051272 181 0.047
regulation of jnk cascade GO:0046328 73 0.047
neurogenesis GO:0022008 169 0.046
nitrogen compound transport GO:0071705 191 0.046
Rat
response to ethanol GO:0045471 11 0.046
microtubule based process GO:0007017 210 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
cell cell junction organization GO:0045216 69 0.046
positive regulation of hydrolase activity GO:0051345 331 0.046
response to nutrient GO:0007584 20 0.045
atrial cardiac muscle cell action potential GO:0086014 6 0.045
positive regulation of catabolic process GO:0009896 310 0.045
circulatory system development GO:0072359 262 0.045
regulation of protein localization to plasma membrane GO:1903076 40 0.045
regulation of hormone levels GO:0010817 125 0.045
regulation of stress activated mapk cascade GO:0032872 84 0.044
actin filament based process GO:0030029 224 0.044
purine containing compound biosynthetic process GO:0072522 88 0.044
filopodium assembly GO:0046847 18 0.044
regulation of cellular protein catabolic process GO:1903362 96 0.044
regulation of glutamate receptor signaling pathway GO:1900449 6 0.044
positive regulation of cell division GO:0051781 59 0.043
reactive oxygen species metabolic process GO:0072593 75 0.043
response to cocaine GO:0042220 1 0.042
Rat
regulation of jak stat cascade GO:0046425 44 0.042
cell morphogenesis GO:0000902 296 0.042
dendritic spine morphogenesis GO:0060997 3 0.041
response to carbohydrate GO:0009743 21 0.041
Rat
regulation of erbb signaling pathway GO:1901184 27 0.041
neuron projection morphogenesis GO:0048812 50 0.041
microtubule cytoskeleton organization GO:0000226 176 0.041
nucleocytoplasmic transport GO:0006913 176 0.041
ribonucleotide biosynthetic process GO:0009260 81 0.040
regulation of dendrite development GO:0050773 18 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
forebrain development GO:0030900 26 0.040
Rat
regulation of epithelial cell proliferation GO:0050678 113 0.040
regulation of gtp catabolic process GO:0033124 180 0.040
regulation of cardiac muscle tissue growth GO:0055021 4 0.040
positive regulation of cell migration GO:0030335 172 0.040
regulation of intracellular protein transport GO:0033157 123 0.040
hindbrain development GO:0030902 3 0.040
limbic system development GO:0021761 3 0.039
Rat
ribonucleoside catabolic process GO:0042454 406 0.039
regulation of reactive oxygen species metabolic process GO:2000377 41 0.039
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.039
regulation of protein kinase b signaling GO:0051896 61 0.039
regulation of cell differentiation GO:0045595 393 0.039
posttranscriptional regulation of gene expression GO:0010608 213 0.039
establishment of protein localization to plasma membrane GO:0090002 68 0.039
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.038
positive regulation of kinase activity GO:0033674 204 0.038
associative learning GO:0008306 1 0.038
Rat
multicellular organismal homeostasis GO:0048871 67 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
adherens junction assembly GO:0034333 34 0.037
synaptic vesicle endocytosis GO:0048488 2 0.037
receptor transactivation GO:0035624 4 0.037
erbb signaling pathway GO:0038127 44 0.037
negative regulation of synaptic transmission GO:0050805 2 0.037
vesicle mediated transport GO:0016192 371 0.037
cellular protein catabolic process GO:0044257 261 0.037
hormone secretion GO:0046879 65 0.037
regulation of mitotic cell cycle phase transition GO:1901990 118 0.037
positive regulation of cell cycle process GO:0090068 106 0.036
protein targeting GO:0006605 187 0.036
negative adaptation of signaling pathway GO:0022401 7 0.036
purine ribonucleotide biosynthetic process GO:0009152 79 0.036
regulation of heart growth GO:0060420 4 0.036
neuron apoptotic process GO:0051402 39 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.035
regulation of transferase activity GO:0051338 355 0.035
negative regulation of peptide hormone secretion GO:0090278 10 0.035
regulation of dendrite morphogenesis GO:0048814 11 0.035
circulatory system process GO:0003013 113 0.035
negative regulation of hormone secretion GO:0046888 15 0.035
regulation of circadian rhythm GO:0042752 11 0.035
regulation of protein ubiquitination GO:0031396 95 0.034
positive regulation of nucleotide catabolic process GO:0030813 185 0.034
carbohydrate derivative biosynthetic process GO:1901137 207 0.034
reactive oxygen species biosynthetic process GO:1903409 4 0.034
nucleotide catabolic process GO:0009166 408 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.034
synaptic vesicle transport GO:0048489 5 0.034
multicellular organismal signaling GO:0035637 34 0.034
regulation of microtubule based process GO:0032886 74 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.033
protein localization to organelle GO:0033365 280 0.033

GRIN2B disease predictions

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 41 0.045
Human
central nervous system disease DOID:331 186 0.045
Human
brain disease DOID:936 73 0.045
Human
electroclinical syndrome DOID:0050701 32 0.045
Human
nervous system disease DOID:863 431 0.045
Human
cancer DOID:162 167 0.043
disease of cellular proliferation DOID:14566 174 0.043
organ system cancer DOID:0050686 164 0.043
neurodegenerative disease DOID:1289 102 0.040
sensory system disease DOID:0050155 203 0.038