|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
1.000
|
Rat Fly |
|
|
right ventricular cardiac muscle tissue morphogenesis
|
GO:0003221 |
2 |
1.000
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
1.000
|
Worm Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
1.000
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.999
|
Human Rat Fly |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.999
|
Mouse Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.999
|
Rat Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.997
|
Rat Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.997
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.997
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.997
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.997
|
Fly |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.996
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.994
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.994
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.993
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.993
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.993
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.993
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.993
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.992
|
Mouse Rat |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.992
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.991
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.991
|
Mouse Fly |
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.990
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.989
|
Rat Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.989
|
|
|
|
regulation of phospholipase c activating g protein coupled receptor signaling pathway
|
GO:1900736 |
1 |
0.989
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.988
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.987
|
Worm Fly |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.987
|
Mouse Fly |
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.986
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.985
|
Worm |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.985
|
Rat Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.985
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.984
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.984
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.982
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.980
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.979
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.979
|
Mouse Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.978
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.978
|
Rat Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.977
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.977
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.977
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.977
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.974
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.974
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.973
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.972
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.972
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.972
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.971
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.970
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.970
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.969
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.968
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.967
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.967
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.966
|
Rat Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.966
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.966
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.966
|
Mouse Rat Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.965
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.965
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.965
|
Mouse Rat |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.963
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.962
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.962
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.961
|
Worm Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.960
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.960
|
Rat Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.957
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.956
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.954
|
Rat Fly |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.954
|
Rat Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.953
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.952
|
Mouse Fly |
|
|
microtubule anchoring at microtubule organizing center
|
GO:0072393 |
1 |
0.952
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.952
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.951
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.951
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.949
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.948
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.948
|
Human Rat Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.946
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.945
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.944
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.944
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.944
|
Mouse |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.943
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.943
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.939
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.937
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.935
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.935
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.935
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.935
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.933
|
|
|
|
system process
|
GO:0003008 |
349 |
0.932
|
Mouse Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.932
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.930
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.930
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.929
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.929
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.928
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.927
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.924
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.924
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.923
|
Mouse Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.922
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.922
|
Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.922
|
Rat Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.921
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.921
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.920
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.920
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.918
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.911
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.910
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.909
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.909
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.906
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.905
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.904
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.898
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.898
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.896
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.894
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.893
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.893
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.888
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.887
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.886
|
Worm Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.884
|
Mouse Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.883
|
Mouse Rat Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.880
|
Mouse Rat |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.877
|
Mouse Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.877
|
Rat Fly |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.876
|
Fly |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.876
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.876
|
Worm Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.873
|
Rat Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.871
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.870
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.870
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.870
|
Human |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.869
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.868
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.866
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.862
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.862
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.861
|
Rat Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.861
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.861
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.861
|
Mouse Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.861
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.857
|
Mouse Rat |
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.849
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.848
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.847
|
Worm Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.845
|
Mouse Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.844
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.843
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.843
|
Mouse Rat Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.841
|
Rat Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.840
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.840
|
Human |
|
|
negative regulation of non canonical wnt signaling pathway
|
GO:2000051 |
1 |
0.839
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.839
|
Rat |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.836
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.835
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.835
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.834
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.833
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.833
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.831
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.831
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.830
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.830
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.827
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.826
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.826
|
Mouse Fly |
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.825
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.824
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.818
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.818
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.817
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.813
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.813
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.811
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.809
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.808
|
Mouse Worm |
|
|
forebrain development
|
GO:0030900 |
26 |
0.806
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.801
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.800
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.797
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.797
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.791
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.790
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.789
|
Mouse Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.788
|
Mouse Fly |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.788
|
Mouse Fly |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.786
|
Rat Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.784
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.782
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.778
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.777
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.775
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.774
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.771
|
Human Rat Fly |
|
|
developmental growth
|
GO:0048589 |
48 |
0.765
|
Mouse Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.764
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.762
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.759
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.759
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.757
|
Worm |
|
|
pharynx development
|
GO:0060465 |
1 |
0.756
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.756
|
Mouse Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.754
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.753
|
Worm Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.752
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.749
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.747
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.746
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.745
|
Mouse Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.740
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.739
|
Mouse Fly |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.736
|
Mouse Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.734
|
Mouse Rat Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.729
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.728
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.728
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.723
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.722
|
Rat |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.719
|
Mouse |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.718
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.706
|
Rat Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.703
|
Mouse Fly |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.701
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.700
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.700
|
Mouse Rat Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.700
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.694
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.694
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.693
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.691
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.690
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.684
|
Fly |
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.681
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.680
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.672
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.671
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.667
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.666
|
Mouse Worm |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.660
|
Mouse |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.659
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.653
|
Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.650
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.648
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.647
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.645
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.644
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.642
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.640
|
Worm |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.638
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.635
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.627
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.627
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.623
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.623
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.619
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.616
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.614
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.612
|
Rat Fly |
|
|
heart formation
|
GO:0060914 |
2 |
0.609
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.608
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.606
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.606
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.605
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.603
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.601
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.601
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.599
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.598
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.598
|
|
|
|
growth
|
GO:0040007 |
202 |
0.598
|
Mouse Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.597
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.596
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.594
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.594
|
Fly |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.594
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.593
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.587
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.584
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.581
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.578
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.577
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.577
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.577
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.576
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.573
|
Mouse Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.571
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.569
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.569
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.565
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.560
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.558
|
|
|
|
positive regulation of neurotransmitter transport
|
GO:0051590 |
1 |
0.553
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.552
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.550
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.550
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.547
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.547
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.546
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.544
|
Mouse Fly |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.539
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.537
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.537
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.537
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.534
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.531
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.530
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.529
|
Worm Fly |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.529
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.528
|
|
|
|
head development
|
GO:0060322 |
108 |
0.526
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.526
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.526
|
Rat Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.521
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.519
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.517
|
Fly |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.515
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.515
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.510
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.509
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.508
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.506
|
Rat Fly |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.503
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.502
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.502
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.502
|
Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.500
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.498
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.494
|
|
|
|
negative regulation of interleukin 4 production
|
GO:0032713 |
3 |
0.487
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.484
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.479
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.479
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.478
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.475
|
Human |
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.475
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.474
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.470
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.470
|
Rat Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.468
|
Fly |
|
|
single organism behavior
|
GO:0044708 |
28 |
0.463
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.462
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.461
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.459
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.458
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.456
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.456
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.454
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.451
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.450
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.450
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.449
|
Mouse Rat |
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.446
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.444
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.443
|
Mouse Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.434
|
Mouse Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.431
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.427
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.423
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.423
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.422
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.421
|
Mouse Fly |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.421
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.419
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.419
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.418
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.417
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.416
|
Mouse Rat |
|
|
heart field specification
|
GO:0003128 |
2 |
0.415
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.415
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.414
|
Worm Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.414
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.414
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.410
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.410
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.409
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.408
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.407
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.405
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.403
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.401
|
Worm Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.401
|
Mouse Rat |
|
|
reproductive system development
|
GO:0061458 |
56 |
0.393
|
Worm Fly |
|
|
protein acetylation
|
GO:0006473 |
116 |
0.390
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.390
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.389
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.385
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.384
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.384
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.382
|
Mouse |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.378
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.378
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.377
|
|
|
|
positive regulation of synaptic vesicle transport
|
GO:1902805 |
1 |
0.376
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.373
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.370
|
Worm |
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.368
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.368
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.368
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.368
|
Mouse Rat |
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.366
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.366
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.365
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.364
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.363
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.363
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.360
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.359
|
Worm Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.357
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.351
|
|
|
|
memory
|
GO:0007613 |
3 |
0.351
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.350
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.350
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.345
|
|
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
7 |
0.344
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.342
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.341
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.340
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.339
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.339
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.336
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.335
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.332
|
Mouse |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.331
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.331
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.331
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.330
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.330
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.328
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.326
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.325
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.325
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.324
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.323
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.323
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.320
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.318
|
Mouse Rat |
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.318
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.317
|
Mouse Rat Fly |
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.317
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.315
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.315
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.314
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.313
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.313
|
Mouse Rat |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.312
|
Worm |
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.311
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.309
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.309
|
Worm Fly |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.303
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.302
|
Mouse Rat |
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.302
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.302
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.302
|
Mouse Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.301
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.300
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.299
|
Mouse |
|
|
cell division
|
GO:0051301 |
168 |
0.299
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.297
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.296
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.292
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.292
|
Human |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.291
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.291
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.290
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.289
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.288
|
Fly |
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.288
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.287
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.286
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.286
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.286
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.285
|
Mouse Rat |
