Homo sapiens

14 known processes

H2AFX

H2A histone family, member X

(Aliases: H2AX,H2A/X,H2A.X)

H2AFX biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 101 1.000
Mouse
cellular response to dna damage stimulus GO:0006974 379 1.000
chromatin modification GO:0016568 298 1.000
chromatin organization GO:0006325 351 1.000
Human
covalent chromatin modification GO:0016569 254 1.000
dna repair GO:0006281 198 1.000
Human Yeast Mouse
double strand break repair via homologous recombination GO:0000724 50 1.000
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.999
cell cycle checkpoint GO:0000075 117 0.999
nucleotide excision repair GO:0006289 31 0.999
anatomical structure homeostasis GO:0060249 100 0.998
histone modification GO:0016570 251 0.998
response to radiation GO:0009314 151 0.997
Human
response to abiotic stimulus GO:0009628 336 0.996
Human
regulation of response to dna damage stimulus GO:2001020 94 0.995
telomere capping GO:0016233 5 0.994
dna double strand break processing GO:0000729 10 0.994
g2 dna damage checkpoint GO:0031572 26 0.986
double strand break repair via single strand annealing GO:0045002 4 0.985
histone h3 k4 methylation GO:0051568 27 0.985
dna geometric change GO:0032392 32 0.983
cell aging GO:0007569 52 0.981
non recombinational repair GO:0000726 14 0.980
regulation of cell cycle phase transition GO:1901987 126 0.974
regulation of dna metabolic process GO:0051052 153 0.966
dna recombination GO:0006310 77 0.965
Mouse
negative regulation of cell cycle GO:0045786 193 0.957
response to ionizing radiation GO:0010212 65 0.954
telomere maintenance GO:0000723 32 0.951
double strand break repair via nonhomologous end joining GO:0006303 10 0.948
negative regulation of cell cycle process GO:0010948 121 0.947
mitotic cell cycle phase transition GO:0044772 162 0.937
dna conformation change GO:0071103 113 0.937
Human
telomere organization GO:0032200 33 0.927
recombinational repair GO:0000725 50 0.922
Mouse
dna damage checkpoint GO:0000077 68 0.914
mitotic recombination GO:0006312 8 0.914
regulation of dna repair GO:0006282 47 0.908
regulation of cellular response to stress GO:0080135 244 0.905
intrinsic apoptotic signaling pathway GO:0097193 127 0.893
purine nucleoside monophosphate catabolic process GO:0009128 158 0.890
cardiovascular system development GO:0072358 262 0.866
cellular chemical homeostasis GO:0055082 180 0.861
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.843
oocyte development GO:0048599 1 0.842
septum secundum development GO:0003285 2 0.841
oocyte differentiation GO:0009994 2 0.839
reciprocal dna recombination GO:0035825 4 0.833
circulatory system development GO:0072359 262 0.833
positive regulation of developmental process GO:0051094 314 0.829
regulation of cell cycle GO:0051726 393 0.821
histone lysine methylation GO:0034968 50 0.818
nucleoside monophosphate catabolic process GO:0009125 159 0.813
meiotic chromosome segregation GO:0045132 4 0.811
signal transduction in response to dna damage GO:0042770 57 0.807
blastocyst development GO:0001824 3 0.807
mitotic cell cycle process GO:1903047 286 0.805
dna duplex unwinding GO:0032508 30 0.805
regulation of double strand break repair GO:2000779 22 0.800
spindle checkpoint GO:0031577 26 0.799
base excision repair GO:0006284 21 0.795
chordate embryonic development GO:0043009 34 0.789
cell cycle arrest GO:0007050 71 0.787
purine nucleotide catabolic process GO:0006195 405 0.784
dna catabolic process GO:0006308 49 0.780
mitotic cell cycle checkpoint GO:0007093 68 0.756
nucleoside triphosphate catabolic process GO:0009143 394 0.751
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.749
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.742
positive regulation of cell proliferation GO:0008284 301 0.740
chromatin remodeling GO:0006338 55 0.739
telomere maintenance via recombination GO:0000722 4 0.736
regulation of cell activation GO:0050865 125 0.728
protein alkylation GO:0008213 74 0.717
immune response GO:0006955 307 0.716
positive regulation of dna metabolic process GO:0051054 73 0.712
macromolecule methylation GO:0043414 97 0.704
chromatin assembly or disassembly GO:0006333 78 0.703
Human
positive regulation of cell cycle GO:0045787 140 0.696
histone methylation GO:0016571 60 0.665
regulation of protein autophosphorylation GO:0031952 15 0.651
mitotic dna damage checkpoint GO:0044773 28 0.635
positive regulation of programmed cell death GO:0043068 249 0.597
positive regulation of cellular amine metabolic process GO:0033240 7 0.588
cell cycle phase transition GO:0044770 173 0.583
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.581
g2 m transition of mitotic cell cycle GO:0000086 41 0.577
protein catabolic process GO:0030163 325 0.555
nucleosome assembly GO:0006334 50 0.543
Human
leukocyte activation GO:0045321 164 0.542
dna damage induced protein phosphorylation GO:0006975 5 0.542
cellular macromolecule catabolic process GO:0044265 380 0.537
chromatin silencing GO:0006342 12 0.514
Yeast
isotype switching GO:0045190 3 0.512
protein dna complex subunit organization GO:0071824 80 0.501
Human
response to external biotic stimulus GO:0043207 261 0.475
protein autophosphorylation GO:0046777 123 0.474
cell activation GO:0001775 213 0.472
mitotic cell cycle GO:0000278 326 0.464
regulation of protein processing GO:0070613 150 0.463
meiosis i GO:0007127 4 0.461
negative regulation of protein maturation GO:1903318 142 0.454
dna catabolic process exonucleolytic GO:0000738 17 0.446
negative regulation of cellular protein metabolic process GO:0032269 353 0.445
positive regulation of transferase activity GO:0051347 227 0.418
segmentation GO:0035282 4 0.405
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.399
gene silencing GO:0016458 49 0.394
Human Yeast
response to oxygen containing compound GO:1901700 369 0.394
mitotic g2 dna damage checkpoint GO:0007095 7 0.385
regulation of growth GO:0040008 165 0.383
microtubule cytoskeleton organization GO:0000226 176 0.380
negative regulation of mitotic cell cycle GO:0045930 102 0.379
microtubule based process GO:0007017 210 0.378
cellular response to abiotic stimulus GO:0071214 117 0.375
Human
negative regulation of protein metabolic process GO:0051248 391 0.367
histone h2a phosphorylation GO:1990164 3 0.367
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.354
positive regulation of cell activation GO:0050867 81 0.348
regulation of transferase activity GO:0051338 355 0.342
female gamete generation GO:0007292 2 0.331
cell activation involved in immune response GO:0002263 30 0.324
positive regulation of cellular component organization GO:0051130 376 0.322
negative regulation of proteolysis GO:0045861 132 0.318
response to oxidative stress GO:0006979 121 0.316
response to inorganic substance GO:0010035 127 0.311
immune system development GO:0002520 195 0.311
Human
regulation of cell cycle process GO:0010564 266 0.310
regulation of chromosome segregation GO:0051983 44 0.304
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.297
positive regulation of developmental growth GO:0048639 16 0.293
dna dependent dna replication GO:0006261 44 0.285
internal peptidyl lysine acetylation GO:0018393 97 0.284
dna biosynthetic process GO:0071897 40 0.283
positive regulation of cell death GO:0010942 263 0.281
positive regulation of mitotic cell cycle GO:0045931 60 0.279
cellular response to external stimulus GO:0071496 111 0.270
determination of adult lifespan GO:0008340 2 0.264
reproductive process GO:0022414 106 0.262
Mouse
atp metabolic process GO:0046034 176 0.262
regulation of dna recombination GO:0000018 23 0.262
response to nitrogen compound GO:1901698 184 0.261
regulation of double strand break repair via homologous recombination GO:0010569 11 0.259
replicative cell aging GO:0001302 3 0.255
positive regulation of dna repair GO:0045739 25 0.252
ribonucleoside catabolic process GO:0042454 406 0.246
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.245
lymphocyte activation GO:0046649 133 0.241
oogenesis GO:0048477 2 0.235
positive regulation of immune effector process GO:0002699 40 0.221
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.219
leukocyte mediated immunity GO:0002443 59 0.218
hemopoiesis GO:0030097 180 0.218
Human
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.215
regulation of immune response GO:0050776 201 0.215
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.213
protein methylation GO:0006479 74 0.209
regulation of leukocyte activation GO:0002694 115 0.201
regulation of lymphocyte activation GO:0051249 103 0.195
detection of stimulus GO:0051606 85 0.193
ras protein signal transduction GO:0007265 73 0.192
nucleosome organization GO:0034728 66 0.189
Human
digestion GO:0007586 22 0.181
leukocyte differentiation GO:0002521 98 0.181
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.175
Yeast
response to other organism GO:0051707 261 0.175
positive regulation of multicellular organism growth GO:0040018 6 0.172
regulation of mitotic cell cycle phase transition GO:1901990 118 0.171
positive regulation of leukocyte activation GO:0002696 80 0.170
dna catabolic process endonucleolytic GO:0000737 37 0.170
purine ribonucleoside catabolic process GO:0046130 398 0.168
dna damage response detection of dna damage GO:0042769 3 0.167
t cell activation GO:0042110 99 0.163
positive regulation of organelle organization GO:0010638 195 0.162
multicellular organismal homeostasis GO:0048871 67 0.161
atp catabolic process GO:0006200 157 0.160
dna integrity checkpoint GO:0031570 71 0.156
ribonucleotide catabolic process GO:0009261 405 0.153
actin filament based process GO:0030029 224 0.151
chromosome segregation GO:0007059 114 0.151
amine metabolic process GO:0009308 44 0.149
regulation of protein maturation GO:1903317 150 0.147
positive regulation of cellular component movement GO:0051272 181 0.145
ribonucleoside monophosphate catabolic process GO:0009158 158 0.144
immune effector process GO:0002252 159 0.144
cellular response to oxidative stress GO:0034599 85 0.140
protein acylation GO:0043543 138 0.140
methylation GO:0032259 106 0.140
signal transduction by phosphorylation GO:0023014 297 0.136
positive regulation of phosphorylation GO:0042327 394 0.136
leukocyte proliferation GO:0070661 74 0.135
positive regulation of growth GO:0045927 58 0.133
regulation of dna replication GO:0006275 68 0.131
mitotic dna integrity checkpoint GO:0044774 30 0.130
negative regulation of developmental process GO:0051093 247 0.130
Human
viral life cycle GO:0019058 132 0.129
nuclear division GO:0000280 128 0.128
regulation of b cell activation GO:0050864 24 0.125
mononuclear cell proliferation GO:0032943 71 0.124
regulation of homeostatic process GO:0032844 121 0.123
negative regulation of multicellular organismal process GO:0051241 317 0.123
Human
nucleotide catabolic process GO:0009166 408 0.123
positive regulation of immune system process GO:0002684 283 0.122
anterior posterior axis specification GO:0009948 2 0.122
response to biotic stimulus GO:0009607 276 0.121
post embryonic development GO:0009791 2 0.120
regulation of chromosome organization GO:0033044 103 0.119
organophosphate catabolic process GO:0046434 430 0.119
ubiquitin dependent protein catabolic process GO:0006511 206 0.119
response to gamma radiation GO:0010332 14 0.113
somitogenesis GO:0001756 2 0.111
replication fork processing GO:0031297 13 0.110
system process GO:0003008 349 0.110
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.109
cellular ketone metabolic process GO:0042180 80 0.108
cell projection morphogenesis GO:0048858 129 0.108
protein modification by small protein conjugation GO:0032446 342 0.106
histone acetylation GO:0016573 93 0.105
production of molecular mediator of immune response GO:0002440 37 0.103
regulation of kinase activity GO:0043549 314 0.103
lymphocyte proliferation GO:0046651 70 0.103
regulation of developmental growth GO:0048638 30 0.102
meiotic cell cycle process GO:1903046 8 0.101
adult locomotory behavior GO:0008344 1 0.101
somatic diversification of immune receptors GO:0002200 8 0.098
negative regulation of cellular protein catabolic process GO:1903363 38 0.096
organelle fission GO:0048285 149 0.095
mitochondrion organization GO:0007005 156 0.095
positive regulation of cell cycle process GO:0090068 106 0.095
positive regulation of chromosome organization GO:2001252 41 0.092
cellular component morphogenesis GO:0032989 314 0.091
gene conversion GO:0035822 1 0.090
positive regulation of response to dna damage stimulus GO:2001022 43 0.090
cellular amine metabolic process GO:0044106 41 0.090
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.089
negative regulation of cell cycle phase transition GO:1901988 89 0.089
telomere maintenance via telomere lengthening GO:0010833 9 0.089
single strand break repair GO:0000012 6 0.089
positive regulation of immune response GO:0050778 159 0.088
blastoderm segmentation GO:0007350 2 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.083
multicellular organismal aging GO:0010259 3 0.082
regulation of growth rate GO:0040009 1 0.082
regulation of proteolysis GO:0030162 293 0.080
somatic cell dna recombination GO:0016444 6 0.079
regionalization GO:0003002 29 0.078
positive regulation of hydrolase activity GO:0051345 331 0.077
postreplication repair GO:0006301 12 0.076
purine nucleoside catabolic process GO:0006152 398 0.076
lymphocyte activation involved in immune response GO:0002285 20 0.076
stress activated protein kinase signaling cascade GO:0031098 94 0.076
growth GO:0040007 202 0.075
negative regulation of cellular catabolic process GO:0031330 83 0.073
negative regulation of response to dna damage stimulus GO:2001021 33 0.073
single organism reproductive process GO:0044702 98 0.073
Mouse
regulation of mapk cascade GO:0043408 262 0.073
dna replication GO:0006260 116 0.072
cellular macromolecular complex assembly GO:0034622 324 0.072
Human
dna templated transcription initiation GO:0006352 35 0.072
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.071
multicellular organism growth GO:0035264 8 0.070
cellular component disassembly GO:0022411 92 0.068
Human
negative regulation of organelle organization GO:0010639 126 0.065
negative regulation of dna metabolic process GO:0051053 57 0.064
multi organism cellular process GO:0044764 156 0.063
neuron differentiation GO:0030182 138 0.063
posttranscriptional regulation of gene expression GO:0010608 213 0.063
positive regulation of chromatin modification GO:1903310 30 0.062
positive regulation of cell motility GO:2000147 177 0.062
peptidyl lysine modification GO:0018205 144 0.061
negative regulation of catabolic process GO:0009895 104 0.061
purine nucleoside monophosphate metabolic process GO:0009126 186 0.060
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.059
anatomical structure formation involved in morphogenesis GO:0048646 284 0.059
protein localization to organelle GO:0033365 280 0.058
heart development GO:0007507 95 0.058
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.058
regulation of cellular component biogenesis GO:0044087 281 0.058
positive regulation of histone methylation GO:0031062 12 0.057
negative regulation of cell death GO:0060548 345 0.057
single organism cellular localization GO:1902580 332 0.056
dna replication dependent nucleosome assembly GO:0006335 32 0.055
Human
spindle assembly checkpoint GO:0071173 17 0.055
hematopoietic or lymphoid organ development GO:0048534 186 0.054
Human
nervous system development GO:0007399 293 0.054
t cell proliferation GO:0042098 45 0.054
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.053
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.053
cytoplasmic transport GO:0016482 379 0.053
developmental growth GO:0048589 48 0.052
leukocyte activation involved in immune response GO:0002366 30 0.052
dephosphorylation GO:0016311 209 0.051
cytokinesis GO:0000910 96 0.051
neuron death GO:0070997 65 0.051
regulation of multi organism process GO:0043900 157 0.051
rna catabolic process GO:0006401 71 0.051
positive regulation of catabolic process GO:0009896 310 0.051
response to uv GO:0009411 73 0.050
Human
reproduction GO:0000003 63 0.050
Mouse
atrial septum secundum morphogenesis GO:0003290 1 0.050
regulation of cellular ketone metabolic process GO:0010565 50 0.050
muscle tissue development GO:0060537 62 0.050
positive regulation of cellular component biogenesis GO:0044089 158 0.048
b cell activation GO:0042113 33 0.048
mitotic sister chromatid segregation GO:0000070 53 0.048
positive regulation of ras gtpase activity GO:0032320 117 0.047
dna replication dependent nucleosome organization GO:0034723 32 0.047
Human
atrial septum primum morphogenesis GO:0003289 1 0.047
cell cycle g2 m phase transition GO:0044839 43 0.046
negative regulation of protein processing GO:0010955 142 0.046
organ morphogenesis GO:0009887 147 0.046
positive regulation of apoptotic process GO:0043065 246 0.046
regulation of chromatin organization GO:1902275 56 0.045
secretion GO:0046903 254 0.043
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.043
response to organic cyclic compound GO:0014070 204 0.043
cellular amino acid metabolic process GO:0006520 116 0.042
cellular homeostasis GO:0019725 196 0.042
cell projection organization GO:0030030 252 0.042
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.042
nucleoside monophosphate metabolic process GO:0009123 191 0.042
oxidative stress induced premature senescence GO:0090403 3 0.041
response to organonitrogen compound GO:0010243 156 0.041
epithelial cell development GO:0002064 34 0.041
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.041
response to transforming growth factor beta GO:0071559 94 0.041
regulation of protein catabolic process GO:0042176 155 0.040
small gtpase mediated signal transduction GO:0007264 78 0.040
regulation of mitosis GO:0007088 63 0.040
regulation of viral process GO:0050792 103 0.039
regulation of multicellular organism growth GO:0040014 8 0.039
dna replication independent nucleosome assembly GO:0006336 27 0.038
Human
cellular response to growth factor stimulus GO:0071363 197 0.038
somatic diversification of immunoglobulins GO:0016445 6 0.038
histone phosphorylation GO:0016572 16 0.038
signal transduction by p53 class mediator GO:0072331 72 0.038
regulation of stress activated mapk cascade GO:0032872 84 0.038
central nervous system development GO:0007417 123 0.038
tripartite regional subdivision GO:0007351 2 0.038
regulation of dna templated transcription elongation GO:0032784 23 0.038
positive regulation of adaptive immune response GO:0002821 21 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.037
cellular response to organonitrogen compound GO:0071417 124 0.037
reciprocal meiotic recombination GO:0007131 4 0.036
dna synthesis involved in dna repair GO:0000731 6 0.035
response to reactive oxygen species GO:0000302 61 0.034
mitotic spindle checkpoint GO:0071174 18 0.034
cellular response to ionizing radiation GO:0071479 32 0.034
regulation of mononuclear cell proliferation GO:0032944 65 0.034
positive regulation of kinase activity GO:0033674 204 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
locomotory behavior GO:0007626 1 0.033
histone h3 k9 modification GO:0061647 11 0.033
regulation of response to external stimulus GO:0032101 222 0.033
regulation of neuron apoptotic process GO:0043523 35 0.033
aging GO:0007568 66 0.033
negative regulation of sister chromatid segregation GO:0033046 17 0.033
blood circulation GO:0008015 113 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.032
male gamete generation GO:0048232 22 0.032
Mouse
response to hypoxia GO:0001666 96 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.032
nuclear import GO:0051170 106 0.032
neuromuscular junction development GO:0007528 3 0.032
negative regulation of mitosis GO:0045839 24 0.031
centrosome organization GO:0051297 58 0.031
regulation of cell development GO:0060284 161 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
positive regulation of lymphocyte activation GO:0051251 73 0.030
response to hydrogen peroxide GO:0042542 40 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
cellular response to radiation GO:0071478 65 0.029
Human
regulation of ras protein signal transduction GO:0046578 155 0.029
meiotic cell cycle GO:0051321 13 0.029
negative regulation of dna dependent dna replication GO:2000104 9 0.029
intracellular protein transport GO:0006886 270 0.029
regulation of endopeptidase activity GO:0052548 170 0.028
cellular lipid metabolic process GO:0044255 303 0.028
regulation of neurogenesis GO:0050767 82 0.028
protein homooligomerization GO:0051260 100 0.028
connective tissue development GO:0061448 39 0.027
translation GO:0006412 132 0.027
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.027
mitotic nuclear division GO:0007067 119 0.027
apoptotic signaling pathway GO:0097190 268 0.027
regulation of neuron death GO:1901214 56 0.027
regulation of dna dependent dna replication GO:0090329 19 0.026
neuromuscular process GO:0050905 15 0.026
ion homeostasis GO:0050801 230 0.026
cell morphogenesis GO:0000902 296 0.026
intracellular mrna localization GO:0008298 1 0.026
detection of peptidoglycan GO:0032499 1 0.026
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.025
embryo development GO:0009790 123 0.025
positive regulation of meiotic cell cycle GO:0051446 2 0.024
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.024
signal transduction involved in dna damage checkpoint GO:0072422 15 0.024
hindbrain development GO:0030902 3 0.024
regulation of cellular protein catabolic process GO:1903362 96 0.024
glycogen catabolic process GO:0005980 4 0.024
circulatory system process GO:0003013 113 0.024
positive regulation of histone h3 k4 methylation GO:0051571 8 0.023
mitotic g2 m transition checkpoint GO:0044818 9 0.023
positive regulation of protein complex assembly GO:0031334 86 0.023
regulation of protein polymerization GO:0032271 63 0.023
cell development GO:0048468 328 0.023
oocyte maturation GO:0001556 1 0.023
mitotic spindle assembly checkpoint GO:0007094 14 0.022
metencephalon development GO:0022037 2 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
protein dephosphorylation GO:0006470 81 0.022
developmental process involved in reproduction GO:0003006 66 0.022
blood vessel development GO:0001568 172 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.022
negative regulation of cell division GO:0051782 31 0.022
negative regulation of gene expression epigenetic GO:0045814 19 0.022
Yeast
lymphocyte differentiation GO:0030098 35 0.022
head development GO:0060322 108 0.021
regulation of meiotic cell cycle GO:0051445 4 0.021
alpha beta t cell differentiation GO:0046632 7 0.021
response to bacterium GO:0009617 144 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
digestive tract morphogenesis GO:0048546 56 0.020
regulation of signal transduction by p53 class mediator GO:1901796 26 0.020
regulation of transcription by chromatin organization GO:0034401 1 0.020
negative regulation of cell size GO:0045792 3 0.020
response to light stimulus GO:0009416 87 0.019
Human
regulation of cellular component movement GO:0051270 334 0.019
response to hyperoxia GO:0055093 4 0.019
protein acetylation GO:0006473 116 0.019
cellular response to uv GO:0034644 32 0.019
Human
reproductive structure development GO:0048608 55 0.019
male meiosis GO:0007140 1 0.019
regulation of gene expression epigenetic GO:0040029 73 0.019
Yeast
humoral immune response GO:0006959 49 0.019
negative regulation of protein catabolic process GO:0042177 59 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
nucleoside catabolic process GO:0009164 408 0.018
multi organism reproductive process GO:0044703 54 0.018
Mouse
smooth muscle cell apoptotic process GO:0034390 6 0.018
cell part morphogenesis GO:0032990 137 0.018
tissue homeostasis GO:0001894 63 0.018
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
establishment of nucleus localization GO:0040023 1 0.018
glomerular mesangial cell development GO:0072144 1 0.017
cellular protein catabolic process GO:0044257 261 0.017
forebrain development GO:0030900 26 0.017
response to nutrient levels GO:0031667 81 0.017
protein secretion GO:0009306 98 0.017
negative regulation of protein localization to nucleus GO:1900181 34 0.017
sister chromatid segregation GO:0000819 54 0.016
regulation of fibroblast proliferation GO:0048145 32 0.016
stem cell development GO:0048864 69 0.016
cell division GO:0051301 168 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of secretion GO:0051046 194 0.016
positive regulation of t cell apoptotic process GO:0070234 4 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
response to oxygen levels GO:0070482 100 0.015
mrna catabolic process GO:0006402 56 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
positive regulation of histone h3 k9 methylation GO:0051574 3 0.015
response to molecule of bacterial origin GO:0002237 82 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
dna ligation GO:0006266 10 0.015
regulation of histone acetylation GO:0035065 19 0.015
response to purine containing compound GO:0014074 40 0.015
cellular response to lipid GO:0071396 127 0.015
regulation of b cell mediated immunity GO:0002712 7 0.015

H2AFX disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.900
cancer DOID:162 167 0.888
thoracic cancer DOID:5093 21 0.777
organ system cancer DOID:0050686 164 0.777
breast cancer DOID:1612 21 0.430
central nervous system disease DOID:331 186 0.175
nervous system disease DOID:863 431 0.175
immune system disease DOID:2914 155 0.096
bone marrow disease DOID:4961 31 0.096
hematopoietic system disease DOID:74 100 0.096
neurodegenerative disease DOID:1289 102 0.081
aplastic anemia DOID:12449 30 0.024
anemia DOID:2355 55 0.024
gastrointestinal system cancer DOID:3119 52 0.023
hepatocellular carcinoma DOID:684 9 0.023
liver carcinoma DOID:686 9 0.023
liver cancer DOID:3571 9 0.023
endocrine gland cancer DOID:170 26 0.018
pancreatic cancer DOID:1793 8 0.018