Homo sapiens

0 known processes

HADHB

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

(Aliases: MGC87480,ECHB,TP-BETA,MTPB)

HADHB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid oxidation GO:0034440 33 1.000
Rat Fly
lipid modification GO:0030258 84 0.999
Rat Fly
monocarboxylic acid catabolic process GO:0072329 37 0.998
Rat Fly
organic acid catabolic process GO:0016054 71 0.995
Rat Fly
fatty acid metabolic process GO:0006631 115 0.994
Rat Fly
lipid catabolic process GO:0016042 84 0.991
Rat Fly
oxidation reduction process GO:0055114 396 0.990
Mouse Rat Fly
carboxylic acid catabolic process GO:0046395 71 0.980
Rat Fly
cellular lipid catabolic process GO:0044242 65 0.969
Rat Fly
lipid metabolic process GO:0006629 381 0.965
Rat Fly
cellular lipid metabolic process GO:0044255 303 0.955
Rat Fly
fatty acid oxidation GO:0019395 31 0.918
Rat Fly
fatty acid beta oxidation GO:0006635 22 0.916
Rat Fly
monocarboxylic acid metabolic process GO:0032787 185 0.882
Rat Fly
small molecule catabolic process GO:0044282 92 0.858
Rat Fly
fatty acid catabolic process GO:0009062 29 0.723
Rat Fly
response to bacterium GO:0009617 144 0.620
determination of adult lifespan GO:0008340 2 0.535
Fly
primary alcohol metabolic process GO:0034308 17 0.426
response to oxygen containing compound GO:1901700 369 0.386
sulfur compound metabolic process GO:0006790 101 0.375
response to organonitrogen compound GO:0010243 156 0.350
organic hydroxy compound metabolic process GO:1901615 147 0.314
response to biotic stimulus GO:0009607 276 0.300
response to external biotic stimulus GO:0043207 261 0.287
sulfur compound biosynthetic process GO:0044272 38 0.285
response to hormone GO:0009725 175 0.276
post embryonic development GO:0009791 2 0.270
multicellular organismal aging GO:0010259 3 0.245
Fly
protein homooligomerization GO:0051260 100 0.234
ribonucleoside triphosphate catabolic process GO:0009203 391 0.232
fatty acid beta oxidation using acyl coa dehydrogenase GO:0033539 3 0.210
diterpenoid metabolic process GO:0016101 20 0.198
immune response GO:0006955 307 0.160
cytoplasmic transport GO:0016482 379 0.159
purine nucleoside triphosphate metabolic process GO:0009144 412 0.152
terpenoid metabolic process GO:0006721 27 0.147
response to peptide hormone GO:0043434 61 0.136
guanosine containing compound metabolic process GO:1901068 244 0.136
membrane organization GO:0061024 292 0.122
response to abiotic stimulus GO:0009628 336 0.120
osteoblast differentiation GO:0001649 92 0.116
alcohol metabolic process GO:0006066 114 0.116
purine ribonucleoside metabolic process GO:0046128 437 0.111
response to starvation GO:0042594 59 0.110
ribonucleotide catabolic process GO:0009261 405 0.097
lipid localization GO:0010876 106 0.097
secretion GO:0046903 254 0.095
response to nitrogen compound GO:1901698 184 0.091
protein tetramerization GO:0051262 47 0.088
regulation of transferase activity GO:0051338 355 0.087
energy derivation by oxidation of organic compounds GO:0015980 43 0.086
wound healing GO:0042060 115 0.086
isoprenoid metabolic process GO:0006720 39 0.085
protein oligomerization GO:0051259 173 0.085
negative regulation of catalytic activity GO:0043086 335 0.082
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.080
vesicle mediated transport GO:0016192 371 0.074
response to other organism GO:0051707 261 0.071
response to extracellular stimulus GO:0009991 85 0.068
response to nutrient levels GO:0031667 81 0.068
generation of precursor metabolites and energy GO:0006091 68 0.066
peroxisome organization GO:0007031 28 0.066
aging GO:0007568 66 0.065
Fly
defense response to other organism GO:0098542 129 0.065
maintenance of location GO:0051235 112 0.064
purine containing compound catabolic process GO:0072523 411 0.061
defense response to bacterium GO:0042742 63 0.057
negative regulation of protein metabolic process GO:0051248 391 0.054
regeneration GO:0031099 4 0.054
response to insulin GO:0032868 45 0.053
cellular amine metabolic process GO:0044106 41 0.053
triglyceride metabolic process GO:0006641 23 0.053
response to salt stress GO:0009651 3 0.052
innate immune response GO:0045087 178 0.052
cellular sodium ion homeostasis GO:0006883 8 0.051
ribonucleoside monophosphate metabolic process GO:0009161 187 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.050
single organism membrane organization GO:0044802 268 0.048
cellular response to endogenous stimulus GO:0071495 336 0.048
phytol metabolic process GO:0033306 2 0.047
glycosyl compound catabolic process GO:1901658 413 0.046
cellular respiration GO:0045333 21 0.046
regulation of gtp catabolic process GO:0033124 180 0.045
purine ribonucleoside catabolic process GO:0046130 398 0.045
nucleotide catabolic process GO:0009166 408 0.044
ribonucleoside catabolic process GO:0042454 406 0.044
regulation of secretion GO:0051046 194 0.043
female gamete generation GO:0007292 2 0.043
intracellular protein transport GO:0006886 270 0.043
nucleoside catabolic process GO:0009164 408 0.042
microtubule cytoskeleton organization GO:0000226 176 0.041
protein localization to organelle GO:0033365 280 0.041
ossification GO:0001503 121 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
organophosphate catabolic process GO:0046434 430 0.041
fatty alcohol metabolic process GO:1903173 2 0.040
regulation of protein kinase activity GO:0045859 289 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
endocytosis GO:0006897 159 0.040
thioester metabolic process GO:0035383 23 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.038
protein homotetramerization GO:0051289 28 0.037
purine nucleoside monophosphate metabolic process GO:0009126 186 0.037
intracellular protein transmembrane import GO:0044743 23 0.037
aerobic respiration GO:0009060 7 0.037
defense response GO:0006952 315 0.036
branched chain amino acid metabolic process GO:0009081 4 0.035
cellular ketone metabolic process GO:0042180 80 0.035
protein maturation GO:0051604 233 0.035
cellular response to reactive oxygen species GO:0034614 50 0.035
cellular response to oxygen containing compound GO:1901701 276 0.033
protein localization to membrane GO:0072657 160 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
amine metabolic process GO:0009308 44 0.031
protein ubiquitination GO:0016567 314 0.031
neutral lipid metabolic process GO:0006638 27 0.030
reproductive process GO:0022414 106 0.030
negative regulation of cell death GO:0060548 345 0.029
positive regulation of gtpase activity GO:0043547 166 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
negative regulation of transferase activity GO:0051348 124 0.029
cellular response to oxygen levels GO:0071453 55 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
lipid biosynthetic process GO:0008610 177 0.027
brain development GO:0007420 97 0.027
nucleoside monophosphate metabolic process GO:0009123 191 0.027
establishment of protein localization to membrane GO:0090150 121 0.026
organonitrogen compound biosynthetic process GO:1901566 200 0.026
osteoclast development GO:0036035 2 0.025
lipid storage GO:0019915 28 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
protein processing GO:0016485 226 0.025
head development GO:0060322 108 0.024
transmembrane transport GO:0055085 399 0.024
cellular response to hydrogen peroxide GO:0070301 37 0.023
cd8 positive alpha beta t cell activation GO:0036037 3 0.023
ras protein signal transduction GO:0007265 73 0.023
regulation of cell differentiation GO:0045595 393 0.023
regulation of secretion by cell GO:1903530 177 0.023
acyl coa metabolic process GO:0006637 23 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
circulatory system development GO:0072359 262 0.022
negative regulation of transport GO:0051051 176 0.022
negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 1 0.022
regulation of gtpase activity GO:0043087 180 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.021
oocyte differentiation GO:0009994 2 0.021
purine nucleotide biosynthetic process GO:0006164 84 0.021
mating GO:0007618 1 0.021
endosomal transport GO:0016197 129 0.020
defense response to gram negative bacterium GO:0050829 14 0.020
secretion by cell GO:0032940 226 0.020
negative regulation of protein processing GO:0010955 142 0.020
metencephalon development GO:0022037 2 0.020
single organism cellular localization GO:1902580 332 0.020
positive regulation of catabolic process GO:0009896 310 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
response to decreased oxygen levels GO:0036293 96 0.019
polysaccharide metabolic process GO:0005976 33 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
receptor mediated endocytosis GO:0006898 84 0.018
response to inorganic substance GO:0010035 127 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
segmentation GO:0035282 4 0.018
positive regulation of secretion GO:0051047 116 0.018
regulation of proteolysis GO:0030162 293 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
neuromuscular junction development GO:0007528 3 0.017
monovalent inorganic cation transport GO:0015672 128 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
regulation of protein transport GO:0051223 213 0.017
oogenesis GO:0048477 2 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
cellular response to hypoxia GO:0071456 51 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
ion homeostasis GO:0050801 230 0.017
ion transmembrane transport GO:0034220 338 0.017
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.017
response to reactive oxygen species GO:0000302 61 0.017
gtp metabolic process GO:0046039 239 0.017
nervous system development GO:0007399 293 0.016
hemoglobin metabolic process GO:0020027 3 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
cellular component morphogenesis GO:0032989 314 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
system process GO:0003008 349 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
protein targeting GO:0006605 187 0.016
apoptotic signaling pathway GO:0097190 268 0.016
spermatid differentiation GO:0048515 4 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
response to nutrient GO:0007584 20 0.015
cellular protein catabolic process GO:0044257 261 0.015
cell projection organization GO:0030030 252 0.015
carbohydrate metabolic process GO:0005975 207 0.015
branched chain amino acid catabolic process GO:0009083 4 0.015
response to radiation GO:0009314 151 0.015
response to metal ion GO:0010038 84 0.015
hindbrain development GO:0030902 3 0.015
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.015
cellular amino acid catabolic process GO:0009063 31 0.014
cellular response to decreased oxygen levels GO:0036294 51 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.014
negative regulation of protein modification process GO:0031400 200 0.014
gtp catabolic process GO:0006184 237 0.014
hemopoiesis GO:0030097 180 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
cholesterol metabolic process GO:0008203 28 0.014
response to uv GO:0009411 73 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
steroid metabolic process GO:0008202 94 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
rho protein signal transduction GO:0007266 26 0.013
regulation of cellular response to hepatocyte growth factor stimulus GO:2001112 1 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
microtubule based process GO:0007017 210 0.013
response to lipid GO:0033993 206 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
nucleoside diphosphate metabolic process GO:0009132 16 0.013
tricarboxylic acid cycle GO:0006099 4 0.013
protein localization to plasma membrane GO:0072659 93 0.013
interleukin 12 secretion GO:0072610 1 0.013
very long chain fatty acid metabolic process GO:0000038 19 0.013
protein import GO:0017038 130 0.013
sulfur amino acid metabolic process GO:0000096 14 0.013
mitochondrion organization GO:0007005 156 0.013
nerve development GO:0021675 4 0.013
neutrophil homeostasis GO:0001780 3 0.013
substantia nigra development GO:0021762 45 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
proteoglycan catabolic process GO:0030167 3 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
response to steroid hormone GO:0048545 80 0.012
regulation of protein processing GO:0070613 150 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
cell projection morphogenesis GO:0048858 129 0.012
cellular hormone metabolic process GO:0034754 41 0.012
response to light stimulus GO:0009416 87 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
negative regulation of protein transport GO:0051224 75 0.012
citrate metabolic process GO:0006101 2 0.012
establishment of protein localization to organelle GO:0072594 172 0.011
positive regulation of vesicle fusion GO:0031340 4 0.011
alpha amino acid metabolic process GO:1901605 72 0.011
endomembrane system organization GO:0010256 196 0.011
negative regulation of protein maturation GO:1903318 142 0.011
cell activation GO:0001775 213 0.011
negative regulation of multi organism process GO:0043901 92 0.011
response to camp GO:0051591 25 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
spermatid development GO:0007286 4 0.011
regulation of protein secretion GO:0050708 86 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
cation transport GO:0006812 331 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
negative regulation of interleukin 1 mediated signaling pathway GO:2000660 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
response to activity GO:0014823 0 0.010
cellular macromolecule catabolic process GO:0044265 380 0.010
response to peptide GO:1901652 65 0.010
coenzyme a metabolic process GO:0015936 6 0.010
response to drug GO:0042493 81 0.010
polyol metabolic process GO:0019751 32 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
epidermis morphogenesis GO:0048730 3 0.010
regulation of neurogenesis GO:0050767 82 0.010
regulation of peptide secretion GO:0002791 42 0.010
peptide metabolic process GO:0006518 51 0.010
neuroblast proliferation GO:0007405 4 0.010
small molecule biosynthetic process GO:0044283 157 0.010
regulation of protein maturation GO:1903317 150 0.010

HADHB disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.820
inherited metabolic disorder DOID:655 242 0.820
hyperinsulinemic hypoglycemia DOID:13317 7 0.114
carbohydrate metabolic disorder DOID:2978 55 0.114
disease of cellular proliferation DOID:14566 174 0.037
musculoskeletal system disease DOID:17 223 0.029
connective tissue disease DOID:65 109 0.029
amino acid metabolic disorder DOID:9252 50 0.025
cancer DOID:162 167 0.019
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
glycogen storage disease DOID:2747 10 0.014
glycogen metabolism disorder DOID:0050728 10 0.014
endocrine gland cancer DOID:170 26 0.014
organ system cancer DOID:0050686 164 0.014