|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
1.000
|
|
|
|
negative regulation of striated muscle contraction
|
GO:0045988 |
2 |
1.000
|
|
|
|
negative regulation of the force of heart contraction by chemical signal
|
GO:0003108 |
1 |
0.999
|
|
|
|
regulation of rhodopsin mediated signaling pathway
|
GO:0022400 |
1 |
0.994
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.992
|
|
|
|
cellular glucuronidation
|
GO:0052695 |
16 |
0.976
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.976
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.931
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.906
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.874
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.873
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.859
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.844
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.842
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.815
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.805
|
Mouse |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.779
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.743
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.717
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.717
|
|
|
|
regulation of catecholamine secretion
|
GO:0050433 |
1 |
0.716
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.713
|
|
|
|
regulation of cellular glucuronidation
|
GO:2001029 |
5 |
0.688
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.681
|
Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.674
|
|
|
|
catecholamine secretion
|
GO:0050432 |
1 |
0.669
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.658
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.653
|
Human |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.652
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.650
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.627
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.623
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.619
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.588
|
Mouse |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.581
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.580
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.577
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.563
|
Mouse |
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.553
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.550
|
|
|
|
adaptation of signaling pathway
|
GO:0023058 |
7 |
0.546
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.540
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.535
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.528
|
Rat |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.527
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
2 |
0.523
|
|
|
|
phototransduction visible light
|
GO:0007603 |
2 |
0.519
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.507
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.498
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.497
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.496
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.485
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.481
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.478
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.459
|
|
|
|
glucuronate metabolic process
|
GO:0019585 |
16 |
0.451
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.443
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.434
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.433
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.414
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.412
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.408
|
|
|
|
uronic acid metabolic process
|
GO:0006063 |
16 |
0.408
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.403
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.397
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.395
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.391
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.386
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.383
|
|
|
|
positive regulation of catecholamine secretion
|
GO:0033605 |
1 |
0.381
|
|
|
|
regulation of amine transport
|
GO:0051952 |
5 |
0.370
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.366
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.363
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.362
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.362
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.358
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
7 |
0.356
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.355
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.355
|
Mouse |
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.354
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.344
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.329
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.329
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.328
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.322
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.319
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.316
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.310
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.305
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.300
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.300
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.299
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.297
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.296
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.289
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.289
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
1 |
0.283
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.279
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.278
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.277
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.271
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.269
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.265
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.260
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.260
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.259
|
|
|
|
detection of light stimulus
|
GO:0009583 |
11 |
0.259
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.256
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.249
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.249
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.243
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.242
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.241
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.240
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.239
|
|
|
|
growth
|
GO:0040007 |
202 |
0.232
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.232
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.230
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.228
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.228
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.226
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.222
|
Rat |
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.219
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.219
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.218
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.218
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.217
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.215
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.213
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.212
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.212
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.209
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.207
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.205
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.201
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.201
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.200
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.197
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.197
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.196
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.195
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.195
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.192
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.186
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.184
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.183
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.183
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.180
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.176
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.176
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.175
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.173
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.173
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.173
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
6 |
0.173
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.171
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.170
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.167
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.167
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.167
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.165
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.162
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.162
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.161
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.161
|
|
|
|
system process
|
GO:0003008 |
349 |
0.160
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.159
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.156
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.155
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.154
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.154
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.153
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.152
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.152
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.147
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
1 |
0.146
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.145
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.144
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.144
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.143
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.142
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.141
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.141
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.140
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.140
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.140
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.138
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.136
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.136
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.134
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.133
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.131
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.129
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.128
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.127
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.127
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.127
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.127
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.127
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.126
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.126
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.123
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.123
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.122
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.122
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.121
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.121
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.120
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.116
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.115
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.114
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.114
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.113
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.113
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.112
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.112
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.110
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.110
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.110
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.109
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.109
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.109
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.108
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.108
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.107
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.107
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.105
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.105
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.105
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.104
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.104
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.103
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.102
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.102
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.100
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.099
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.098
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.097
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.097
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.095
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.095
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.094
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.094
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.092
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.092
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.092
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.092
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.091
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.091
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.091
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.090
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.089
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.089
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.088
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.088
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.088
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.088
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.087
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.086
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.085
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.085
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.084
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.084
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.084
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.084
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.083
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.083
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.083
|
Mouse |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.083
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.083
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.082
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.081
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.081
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.080
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.080
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.079
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.079
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.079
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.078
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.078
|
|
|
|
mating
|
GO:0007618 |
1 |
0.078
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.078
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.078
|
|
|
|
negative regulation of heart contraction
|
GO:0045822 |
3 |
0.077
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.076
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
18 |
0.076
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.076
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.076
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.076
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.075
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.074
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.073
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.073
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.073
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.072
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.072
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.072
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.072
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.071
|
Mouse |
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.071
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.070
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.070
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.070
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.070
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.069
|
|
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.068
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.068
|
Rat |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.068
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.068
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.067
|
|
|
|
necroptotic process
|
GO:0070266 |
16 |
0.067
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.067
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.067
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.066
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.066
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.065
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.065
|
|
|
|
desmosome assembly
|
GO:0002159 |
4 |
0.064
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.064
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.064
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.063
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.062
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.062
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
1 |
0.062
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.061
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.060
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.059
|
|
|
|
catecholamine transport
|
GO:0051937 |
6 |
0.058
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.058
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.058
|
|
|
|
cellular response to epinephrine stimulus
|
GO:0071872 |
2 |
0.058
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.057
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.057
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.057
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.057
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.057
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.056
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.056
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.056
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.056
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.056
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.056
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.055
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.055
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.055
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.055
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.054
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.054
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.054
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.054
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.054
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.054
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.053
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.053
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.052
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.052
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.052
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.052
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.052
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.051
|
|
|
|
negative regulation of reactive oxygen species metabolic process
|
GO:2000378 |
11 |
0.051
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.051
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.051
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.051
|
|
|
|
ripoptosome assembly
|
GO:0097343 |
1 |
0.050
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.050
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.049
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.049
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.049
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.049
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.049
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.049
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.049
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.048
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.048
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.048
|
|
|
|
head development
|
GO:0060322 |
108 |
0.048
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.048
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.048
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.047
|
Rat |
|
|
epithelium development
|
GO:0060429 |
227 |
0.046
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.046
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.046
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.046
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.046
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.045
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.045
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.045
|
|
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
7 |
0.045
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.044
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.044
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.044
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.044
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.043
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.043
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.043
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.043
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.042
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.042
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.042
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.042
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.042
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.042
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.042
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.041
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.041
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.041
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.041
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.041
|
|
|
|
glucose transport
|
GO:0015758 |
30 |
0.041
|
|
|
|
positive regulation of meiosis
|
GO:0045836 |
2 |
0.041
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.041
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.040
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.040
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.040
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.040
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.040
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.040
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.040
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.039
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.039
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.039
|
|
|
|
amine transport
|
GO:0015837 |
7 |
0.038
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.038
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.038
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.037
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.037
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.037
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.037
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.037
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.035
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.035
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.035
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.035
|
|
|
|
ovarian follicle development
|
GO:0001541 |
5 |
0.035
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.035
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.035
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.035
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.035
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.035
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
5 |
0.035
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.035
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.035
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.034
|
|
|
|
response to epinephrine
|
GO:0071871 |
2 |
0.033
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.033
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.033
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.033
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.033
|
Mouse |
|
|
associative learning
|
GO:0008306 |
1 |
0.033
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.032
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.032
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.032
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.032
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.032
|
Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.032
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.032
|
|
|
|
aging
|
GO:0007568 |
66 |
0.031
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.031
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.031
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.031
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.031
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.031
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.031
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.031
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.031
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.031
|
|
|
|
monoamine transport
|
GO:0015844 |
10 |
0.031
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.031
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.031
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.031
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.030
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.030
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.030
|
|
|
|
spemann organizer formation
|
GO:0060061 |
1 |
0.030
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.029
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.029
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.029
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.029
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.029
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.029
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.028
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.028
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.028
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.028
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.027
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.027
|
|
