Homo sapiens

114 known processes

HES1

hairy and enhancer of split 1, (Drosophila)

(Aliases: bHLHb39,HHL,HRY,FLJ20408,HES-1)

HES1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.518
cardiovascular system development GO:0072358 262 0.516
Mouse
female gamete generation GO:0007292 2 0.461
locomotory behavior GO:0007626 1 0.408
Fly
neuron fate commitment GO:0048663 2 0.274
Mouse
post embryonic development GO:0009791 2 0.271
oogenesis GO:0048477 2 0.270
heart morphogenesis GO:0003007 48 0.269
Mouse
regulation of cell differentiation GO:0045595 393 0.263
regulation of cellular ketone metabolic process GO:0010565 50 0.251
negative regulation of multicellular organismal process GO:0051241 317 0.240
cellular component morphogenesis GO:0032989 314 0.233
Mouse Fly
cellular amino acid metabolic process GO:0006520 116 0.229
circulatory system development GO:0072359 262 0.216
Mouse
negative regulation of cell death GO:0060548 345 0.202
actin cytoskeleton organization GO:0030036 207 0.201
rhythmic behavior GO:0007622 2 0.196
cellular ketone metabolic process GO:0042180 80 0.194
regulation of cellular amino acid metabolic process GO:0006521 6 0.192
epithelial cell differentiation GO:0030855 141 0.191
Mouse Worm
regulation of cell development GO:0060284 161 0.188
Mouse Fly
forebrain neuron differentiation GO:0021879 3 0.180
circadian behavior GO:0048512 2 0.177
hemopoiesis GO:0030097 180 0.177
cellular amine metabolic process GO:0044106 41 0.176
amine metabolic process GO:0009308 44 0.171
negative regulation of cellular protein metabolic process GO:0032269 353 0.168
positive regulation of developmental process GO:0051094 314 0.167
Mouse Fly
epithelial cell migration GO:0010631 119 0.162
nervous system development GO:0007399 293 0.158
Mouse Fly
ameboidal type cell migration GO:0001667 135 0.158
epithelium development GO:0060429 227 0.154
Mouse Worm
cell development GO:0048468 328 0.153
negative regulation of developmental process GO:0051093 247 0.147
cellular response to endogenous stimulus GO:0071495 336 0.146
neuron differentiation GO:0030182 138 0.144
Mouse Fly
response to abiotic stimulus GO:0009628 336 0.143
Fly
canonical wnt signaling pathway GO:0060070 116 0.142
cell cell signaling GO:0007267 155 0.140
Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.139
Mouse Fly
blood vessel development GO:0001568 172 0.139
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.139
rho protein signal transduction GO:0007266 26 0.138
anatomical structure formation involved in morphogenesis GO:0048646 284 0.138
Mouse
positive regulation of catabolic process GO:0009896 310 0.135
negative regulation of protein metabolic process GO:0051248 391 0.135
peripheral nervous system development GO:0007422 2 0.134
system process GO:0003008 349 0.134
hematopoietic or lymphoid organ development GO:0048534 186 0.133
positive regulation of cellular amine metabolic process GO:0033240 7 0.133
morphogenesis of embryonic epithelium GO:0016331 4 0.131
muscle structure development GO:0061061 98 0.130
Mouse
negative regulation of cell proliferation GO:0008285 228 0.127
Mouse
wnt signaling pathway GO:0016055 156 0.125
chromatin organization GO:0006325 351 0.125
response to growth factor GO:0070848 205 0.124
formation of primary germ layer GO:0001704 42 0.124
response to lipid GO:0033993 206 0.124
stress activated protein kinase signaling cascade GO:0031098 94 0.123
positive regulation of cell differentiation GO:0045597 211 0.121
Mouse Fly
tissue migration GO:0090130 119 0.118
regulation of cell motility GO:2000145 299 0.112
retinal ganglion cell axon guidance GO:0031290 2 0.111
blood vessel morphogenesis GO:0048514 162 0.110
Mouse
regulation of kinase activity GO:0043549 314 0.107
negative regulation of apoptotic process GO:0043066 316 0.107
somatic stem cell maintenance GO:0035019 4 0.104
Mouse
response to oxygen containing compound GO:1901700 369 0.104
regulation of canonical wnt signaling pathway GO:0060828 88 0.103
tube development GO:0035295 125 0.102
Mouse Fly
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.102
actin filament based process GO:0030029 224 0.101
negative regulation of cell growth GO:0030308 83 0.101
negative regulation of locomotion GO:0040013 118 0.101
regulation of establishment of protein localization GO:0070201 242 0.099
positive regulation of cell death GO:0010942 263 0.098
organ morphogenesis GO:0009887 147 0.098
Mouse Fly
neuromuscular junction development GO:0007528 3 0.098
regulation of epithelial cell migration GO:0010632 93 0.097
cell migration involved in sprouting angiogenesis GO:0002042 19 0.097
positive regulation of phosphorylation GO:0042327 394 0.095
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.094
oocyte development GO:0048599 1 0.092
endothelial cell migration GO:0043542 86 0.092
regulation of stem cell differentiation GO:2000736 56 0.091
regulation of transferase activity GO:0051338 355 0.090
neurological system process GO:0050877 163 0.090
cell growth GO:0016049 160 0.089
regulation of cellular response to stress GO:0080135 244 0.088
gtp catabolic process GO:0006184 237 0.087
regulation of anatomical structure morphogenesis GO:0022603 286 0.086
Mouse
regulation of cytokine production GO:0001817 232 0.086
motor neuron axon guidance GO:0008045 2 0.086
forebrain generation of neurons GO:0021872 3 0.086
cell fate determination GO:0001709 3 0.085
Mouse
positive regulation of programmed cell death GO:0043068 249 0.085
cellular response to hormone stimulus GO:0032870 125 0.084
regulation of protein kinase activity GO:0045859 289 0.084
cell chemotaxis GO:0060326 112 0.084
mapk cascade GO:0000165 288 0.084
organ formation GO:0048645 3 0.082
Mouse
epithelium migration GO:0090132 119 0.081
regulation of nervous system development GO:0051960 88 0.081
Mouse Fly
glycosyl compound catabolic process GO:1901658 413 0.079
purine nucleoside catabolic process GO:0006152 398 0.078
sprouting angiogenesis GO:0002040 29 0.078
negative regulation of wnt signaling pathway GO:0030178 69 0.078
positive regulation of apoptotic process GO:0043065 246 0.077
epidermis morphogenesis GO:0048730 3 0.077
ras protein signal transduction GO:0007265 73 0.076
cochlea development GO:0090102 1 0.076
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.075
vasculature development GO:0001944 181 0.075
Mouse
cuticle development GO:0042335 1 0.075
cell morphogenesis GO:0000902 296 0.075
Mouse Fly
blood vessel endothelial cell migration GO:0043534 42 0.074
muscle tissue development GO:0060537 62 0.073
guanosine containing compound metabolic process GO:1901068 244 0.073
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.073
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.073
regulation of cell morphogenesis GO:0022604 153 0.072
carbohydrate metabolic process GO:0005975 207 0.070
regulation of cellular amine metabolic process GO:0033238 11 0.069
cardiac right ventricle morphogenesis GO:0003215 3 0.069
gtp metabolic process GO:0046039 239 0.068
cellular response to growth factor stimulus GO:0071363 197 0.068
response to organic cyclic compound GO:0014070 204 0.068
negative regulation of phosphate metabolic process GO:0045936 267 0.068
behavior GO:0007610 112 0.068
Fly
positive regulation of cell proliferation GO:0008284 301 0.067
Human Mouse Fly
regulation of epithelial cell proliferation GO:0050678 113 0.067
digestive tract morphogenesis GO:0048546 56 0.067
regulation of protein maturation GO:1903317 150 0.067
generation of neurons GO:0048699 152 0.066
Mouse Fly
tissue morphogenesis GO:0048729 96 0.065
Mouse
cell junction organization GO:0034330 79 0.065
epithelial cell proliferation GO:0050673 128 0.064
startle response GO:0001964 3 0.064
positive regulation of transferase activity GO:0051347 227 0.064
ribonucleoside triphosphate metabolic process GO:0009199 412 0.064
response to fibroblast growth factor GO:0071774 39 0.064
hindbrain development GO:0030902 3 0.063
Mouse
cell projection organization GO:0030030 252 0.063
Fly
digestive tract development GO:0048565 75 0.063
Mouse
regulation of cell cycle process GO:0010564 266 0.063
Fly
regulation of proteolysis GO:0030162 293 0.062
angiogenesis GO:0001525 147 0.062
urogenital system development GO:0001655 65 0.061
Mouse
regulation of cell migration GO:0030334 289 0.061
secretion GO:0046903 254 0.061
regulation of multi organism process GO:0043900 157 0.061
negative regulation of cellular component movement GO:0051271 106 0.061
neurogenesis GO:0022008 169 0.060
Mouse Fly
negative regulation of endopeptidase activity GO:0010951 84 0.059
kidney epithelium development GO:0072073 25 0.059
Mouse
regulation of jnk cascade GO:0046328 73 0.059
salivary gland morphogenesis GO:0007435 4 0.058
Fly
myeloid cell differentiation GO:0030099 117 0.058
response to hormone GO:0009725 175 0.058
regulation of wnt signaling pathway GO:0030111 123 0.058
enzyme linked receptor protein signaling pathway GO:0007167 303 0.058
Mouse
mesenchyme development GO:0060485 59 0.058
Mouse
modification dependent protein catabolic process GO:0019941 209 0.058
positive regulation of protein kinase activity GO:0045860 190 0.058
negative regulation of cell cycle GO:0045786 193 0.058
negative regulation of protein modification process GO:0031400 200 0.058
negative regulation of programmed cell death GO:0043069 321 0.057
negative regulation of protein maturation GO:1903318 142 0.057
purine ribonucleoside metabolic process GO:0046128 437 0.057
neural tube formation GO:0001841 3 0.057
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.057
negative regulation of growth GO:0045926 97 0.057
regulation of cellular component biogenesis GO:0044087 281 0.057
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
stem cell development GO:0048864 69 0.056
positive regulation of transport GO:0051050 336 0.056
positive regulation of hydrolase activity GO:0051345 331 0.056
positive regulation of kinase activity GO:0033674 204 0.056
response to cocaine GO:0042220 1 0.055
positive regulation of jnk cascade GO:0046330 52 0.055
negative regulation of intracellular signal transduction GO:1902532 183 0.055
coenzyme metabolic process GO:0006732 65 0.055
nucleoside triphosphate catabolic process GO:0009143 394 0.054
positive regulation of cell development GO:0010720 92 0.054
Mouse Fly
positive regulation of cellular component organization GO:0051130 376 0.054
Fly
morphogenesis of an epithelium GO:0002009 60 0.054
Mouse
forebrain regionalization GO:0021871 3 0.054
signal transduction by phosphorylation GO:0023014 297 0.054
negative regulation of cell migration GO:0030336 102 0.054
posttranscriptional regulation of gene expression GO:0010608 213 0.054
regulation of cell cycle GO:0051726 393 0.054
Mouse Fly
taxis GO:0042330 157 0.053
negative regulation of phosphorylation GO:0042326 174 0.053
negative regulation of cell motility GO:2000146 104 0.053
negative regulation of catalytic activity GO:0043086 335 0.053
cellular response to external stimulus GO:0071496 111 0.052
response to oxidative stress GO:0006979 121 0.051
immune response GO:0006955 307 0.051
ion homeostasis GO:0050801 230 0.051
steroid hormone secretion GO:0035929 8 0.050
actin filament organization GO:0007015 128 0.050
chemotaxis GO:0006935 157 0.050
anatomical structure homeostasis GO:0060249 100 0.050
embryo development GO:0009790 123 0.050
Mouse
cellular protein catabolic process GO:0044257 261 0.050
regulation of neural precursor cell proliferation GO:2000177 4 0.050
Fly
regulation of locomotion GO:0040012 329 0.050
head development GO:0060322 108 0.049
Mouse
regulation of response to external stimulus GO:0032101 222 0.049
regulation of peptidase activity GO:0052547 180 0.049
skin development GO:0043588 76 0.049
Mouse Worm
regulation of cell projection organization GO:0031344 107 0.048
regulation of endopeptidase activity GO:0052548 170 0.048
neural crest cell development GO:0014032 3 0.048
Mouse
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.048
segmentation GO:0035282 4 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.048
neuron projection development GO:0031175 106 0.048
Fly
regulation of actin filament based process GO:0032970 141 0.048
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.047
regulation of protein serine threonine kinase activity GO:0071900 179 0.047
mitotic cell cycle GO:0000278 326 0.047
Mouse Fly
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.047
peptidyl tyrosine phosphorylation GO:0018108 170 0.047
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.047
cell projection assembly GO:0030031 126 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
regulation of protein processing GO:0070613 150 0.045
cofactor metabolic process GO:0051186 87 0.045
limbic system development GO:0021761 3 0.045
cytokine production GO:0001816 247 0.045
sulfur compound metabolic process GO:0006790 101 0.045
response to organonitrogen compound GO:0010243 156 0.045
inner ear morphogenesis GO:0042472 4 0.044
neuron projection regeneration GO:0031102 1 0.044
response to biotic stimulus GO:0009607 276 0.044
carbohydrate derivative biosynthetic process GO:1901137 207 0.044
endocrine process GO:0050886 25 0.044
cell cell junction organization GO:0045216 69 0.044
regulation of growth GO:0040008 165 0.044
circadian regulation of gene expression GO:0032922 8 0.043
regulation of stress activated mapk cascade GO:0032872 84 0.042
single organism cell adhesion GO:0098602 179 0.042
regulation of cardioblast differentiation GO:0051890 4 0.042
stress activated mapk cascade GO:0051403 93 0.042
regulation of cardiac muscle cell proliferation GO:0060043 4 0.042
regulation of rho gtpase activity GO:0032319 66 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.041
regulation of cell growth GO:0001558 135 0.041
heart field specification GO:0003128 2 0.041
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.041
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.041
intracellular protein transport GO:0006886 270 0.041
Mouse
nucleoside catabolic process GO:0009164 408 0.041
negative regulation of cell differentiation GO:0045596 171 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
spinal cord development GO:0021510 4 0.041
regulation of hormone levels GO:0010817 125 0.041
regulation of vasculature development GO:1901342 97 0.041
photoreceptor cell maintenance GO:0045494 13 0.040
nucleotide catabolic process GO:0009166 408 0.040
modulation of molecular function in other organism GO:0044359 2 0.040
endodermal cell fate specification GO:0001714 4 0.040
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
positive regulation of map kinase activity GO:0043406 80 0.040
regulation of cytoskeleton organization GO:0051493 177 0.040
endodermal cell fate commitment GO:0001711 4 0.040
regulation of protein localization GO:0032880 296 0.040
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.039
negative regulation of peptidase activity GO:0010466 91 0.039
cell fate commitment involved in pattern specification GO:0060581 1 0.039
regulation of ion transport GO:0043269 189 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
cell part morphogenesis GO:0032990 137 0.038
Fly
regulation of myeloid cell differentiation GO:0045637 81 0.038
negative regulation of immune system process GO:0002683 136 0.038
regulation of cell adhesion GO:0030155 166 0.038
establishment of tissue polarity GO:0007164 3 0.038
mesenchymal cell development GO:0014031 50 0.037
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.037
regulation of mapk cascade GO:0043408 262 0.037
multicellular organismal aging GO:0010259 3 0.037
negative regulation of cell development GO:0010721 48 0.037
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.037
positive regulation of cell migration GO:0030335 172 0.037
ubiquitin dependent protein catabolic process GO:0006511 206 0.037
purine ribonucleotide catabolic process GO:0009154 404 0.037
protein catabolic process GO:0030163 325 0.037
regulation of cysteine type endopeptidase activity GO:2000116 127 0.037
circadian sleep wake cycle process GO:0022410 2 0.036
cation transport GO:0006812 331 0.036
histone acetylation GO:0016573 93 0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.036
Mouse
peptidyl lysine acetylation GO:0018394 101 0.036
organophosphate catabolic process GO:0046434 430 0.036
cardiac chamber morphogenesis GO:0003206 26 0.036
Mouse
chordate embryonic development GO:0043009 34 0.036
Mouse
cellular homeostasis GO:0019725 196 0.035
leukocyte differentiation GO:0002521 98 0.035
cardiac cell fate specification GO:0060912 1 0.035
secretion by cell GO:0032940 226 0.035
renal system development GO:0072001 63 0.035
Mouse
ribonucleoside catabolic process GO:0042454 406 0.035
kidney development GO:0001822 53 0.035
Mouse
response to wounding GO:0009611 168 0.035
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
cardiac chamber formation GO:0003207 2 0.035
regulation of gtp catabolic process GO:0033124 180 0.035
negative regulation of proteolysis GO:0045861 132 0.035
cell differentiation in spinal cord GO:0021515 1 0.035
endothelial cell proliferation GO:0001935 65 0.034
regulation of nucleotide catabolic process GO:0030811 205 0.034
determination of adult lifespan GO:0008340 2 0.034
growth GO:0040007 202 0.034
negative regulation of epithelial cell migration GO:0010633 38 0.034
cellular response to lipid GO:0071396 127 0.034
negative regulation of epithelial cell proliferation GO:0050680 48 0.034
hippocampus development GO:0021766 1 0.033
adult locomotory behavior GO:0008344 1 0.033
Fly
positive regulation of protein phosphorylation GO:0001934 313 0.033
Mouse
circadian sleep wake cycle sleep GO:0050802 2 0.033
protein maturation GO:0051604 233 0.033
regulation of angiogenesis GO:0045765 92 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.033
negative regulation of gliogenesis GO:0014014 3 0.032
Mouse
single organism cellular localization GO:1902580 332 0.032
Mouse
positive regulation of endothelial cell proliferation GO:0001938 37 0.032
myoblast fusion GO:0007520 1 0.032
endodermal cell differentiation GO:0035987 31 0.032
forebrain neuron development GO:0021884 2 0.032
purine nucleotide catabolic process GO:0006195 405 0.031
cell activation GO:0001775 213 0.031
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.031
regulation of cell matrix adhesion GO:0001952 42 0.031
positive regulation of gtp catabolic process GO:0033126 166 0.031
immune system development GO:0002520 195 0.031
negative regulation of cell fate commitment GO:0010454 3 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
biological adhesion GO:0022610 331 0.031
Mouse
single organism membrane organization GO:0044802 268 0.031
regulation of protein catabolic process GO:0042176 155 0.031
neural tube closure GO:0001843 3 0.031
regulation of secretion by cell GO:1903530 177 0.030
regulation of leukocyte differentiation GO:1902105 61 0.030
single organism carbohydrate metabolic process GO:0044723 193 0.030
myeloid leukocyte differentiation GO:0002573 60 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
macromolecule deacylation GO:0098732 41 0.030
meiotic chromosome segregation GO:0045132 4 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
regulation of neurogenesis GO:0050767 82 0.030
Mouse Fly
protein localization to nucleus GO:0034504 136 0.030
Mouse
histone modification GO:0016570 251 0.030
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.030
embryonic organ development GO:0048568 36 0.030
Mouse
epithelial to mesenchymal transition GO:0001837 48 0.029
morphogenesis of a polarized epithelium GO:0001738 3 0.029
positive regulation of locomotion GO:0040017 186 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
i kappab kinase nf kappab signaling GO:0007249 166 0.029
apoptotic signaling pathway GO:0097190 268 0.029
positive regulation of gtpase activity GO:0043547 166 0.029
response to axon injury GO:0048678 1 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
fatty acid metabolic process GO:0006631 115 0.029
oocyte differentiation GO:0009994 2 0.029
central nervous system development GO:0007417 123 0.029
Mouse
positive regulation of gliogenesis GO:0014015 4 0.029
Mouse
regulation of secretion GO:0051046 194 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
lipid localization GO:0010876 106 0.029
protein import GO:0017038 130 0.028
Mouse
circadian rhythm GO:0007623 21 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
response to alcohol GO:0097305 64 0.028
somitogenesis GO:0001756 2 0.028
positive regulation of cell cycle GO:0045787 140 0.028
Mouse Fly
circadian sleep wake cycle GO:0042745 2 0.028
muscle organ development GO:0007517 56 0.028
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.028
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.028
protein localization to organelle GO:0033365 280 0.028
Mouse
maintenance of location GO:0051235 112 0.028
protein kinase b signaling GO:0043491 69 0.027
sex determination GO:0007530 3 0.027
Fly
response to radiation GO:0009314 151 0.027
morphogenesis of a branching structure GO:0001763 21 0.027
metal ion transport GO:0030001 272 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.027
regulation of heart morphogenesis GO:2000826 4 0.027
Mouse
regulation of fat cell differentiation GO:0045598 23 0.027
Mouse
negative regulation of protein processing GO:0010955 142 0.027
stem cell differentiation GO:0048863 93 0.027
neuron projection morphogenesis GO:0048812 50 0.027
Fly
positive regulation of mapk cascade GO:0043410 190 0.027
negative regulation of transferase activity GO:0051348 124 0.027
response to extracellular stimulus GO:0009991 85 0.027
regulation of rho protein signal transduction GO:0035023 79 0.027
cell matrix adhesion GO:0007160 85 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
positive regulation of cellular component movement GO:0051272 181 0.026
cell junction assembly GO:0034329 67 0.026
negative regulation of axonogenesis GO:0050771 4 0.026
regulation of cardiac muscle tissue growth GO:0055021 4 0.026
monovalent inorganic cation transport GO:0015672 128 0.026
negative regulation of mapk cascade GO:0043409 56 0.026
hair cell differentiation GO:0035315 2 0.026
Mouse
establishment of planar polarity GO:0001736 3 0.026
pattern specification process GO:0007389 43 0.026
Mouse Worm
protein deacetylation GO:0006476 38 0.026
brain morphogenesis GO:0048854 1 0.025
embryonic epithelial tube formation GO:0001838 4 0.025
cytoplasmic transport GO:0016482 379 0.025
Mouse
midgut development GO:0007494 1 0.025
regulation of heart induction GO:0090381 2 0.025
central nervous system neuron axonogenesis GO:0021955 3 0.025
response to transforming growth factor beta GO:0071559 94 0.025
chemical homeostasis GO:0048878 306 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
cardiac chamber development GO:0003205 30 0.025
Mouse
tube morphogenesis GO:0035239 95 0.025
Mouse Fly
cell projection morphogenesis GO:0048858 129 0.025
Fly
peptidyl lysine modification GO:0018205 144 0.025
neurotransmitter secretion GO:0007269 4 0.025
regulation of ras gtpase activity GO:0032318 128 0.025
regulation of muscle cell differentiation GO:0051147 31 0.025
rhythmic process GO:0048511 31 0.025
cell cycle g1 s phase transition GO:0044843 80 0.025
response to reactive oxygen species GO:0000302 61 0.024
oocyte maturation GO:0001556 1 0.024
mitotic cell cycle phase transition GO:0044772 162 0.024
negative regulation of cardioblast differentiation GO:0051892 2 0.024
circulatory system process GO:0003013 113 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
syncytium formation by plasma membrane fusion GO:0000768 2 0.024
cellular response to cytokine stimulus GO:0071345 181 0.024
pituitary gland development GO:0021983 2 0.024
Mouse
photoreceptor cell differentiation GO:0046530 2 0.024
mammary gland morphogenesis GO:0060443 2 0.024
lipid transport GO:0006869 90 0.024
postsynaptic membrane organization GO:0001941 2 0.024
innate immune response GO:0045087 178 0.024
protein processing GO:0016485 226 0.024
regulation of heart growth GO:0060420 4 0.023
cardioblast cell fate specification GO:0042685 1 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of endothelial cell differentiation GO:0045601 4 0.023
regulation of actin cytoskeleton organization GO:0032956 116 0.023
heart formation GO:0060914 2 0.023
Mouse
neuroblast proliferation GO:0007405 4 0.023
Fly
negative regulation by host of viral glycoprotein metabolic process GO:0044871 2 0.023
cell cycle phase transition GO:0044770 173 0.023
metanephros development GO:0001656 16 0.023
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.023
modification dependent macromolecule catabolic process GO:0043632 212 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.023
regeneration GO:0031099 4 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.023
Mouse
leukocyte activation GO:0045321 164 0.023
Mouse
astrocyte differentiation GO:0048708 4 0.023
Mouse
regulation of glial cell proliferation GO:0060251 4 0.023
Mouse
metal ion homeostasis GO:0055065 169 0.023
positive regulation of apoptotic signaling pathway GO:2001235 70 0.022
meiosis i GO:0007127 4 0.022
regulation of axon guidance GO:1902667 3 0.022
ventral spinal cord development GO:0021517 1 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
anterior posterior axis specification GO:0009948 2 0.022
negative regulation of myeloid cell differentiation GO:0045638 42 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
epidermis development GO:0008544 59 0.022
Mouse Worm
regulation of ras protein signal transduction GO:0046578 155 0.022
chromatin modification GO:0016568 298 0.022
mitotic cell cycle process GO:1903047 286 0.022
Fly
single organism reproductive process GO:0044702 98 0.022
Mouse
cardiocyte differentiation GO:0035051 23 0.022
Mouse

HES1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.047
disease of cellular proliferation DOID:14566 174 0.047
organ system cancer DOID:0050686 164 0.047
disease of metabolism DOID:0014667 295 0.035
musculoskeletal system disease DOID:17 223 0.031
Human
sensory system disease DOID:0050155 203 0.026
eye and adnexa disease DOID:1492 150 0.026
nervous system disease DOID:863 431 0.026
eye disease DOID:5614 149 0.026
teeth hard tissue disease DOID:214 8 0.023
mouth disease DOID:403 14 0.023
tooth disease DOID:1091 14 0.023
gastrointestinal system disease DOID:77 36 0.023