Homo sapiens

32 known processes

HIBADH

3-hydroxyisobutyrate dehydrogenase

(Aliases: NS5ATP1,MGC40361)

HIBADH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.472
organic acid catabolic process GO:0016054 71 0.347
carboxylic acid catabolic process GO:0046395 71 0.262
small molecule catabolic process GO:0044282 92 0.172
cellular lipid metabolic process GO:0044255 303 0.163
cellular amino acid metabolic process GO:0006520 116 0.154
lipid metabolic process GO:0006629 381 0.134
cellular ketone metabolic process GO:0042180 80 0.119
fatty acid metabolic process GO:0006631 115 0.087
lipid oxidation GO:0034440 33 0.079
peroxisome organization GO:0007031 28 0.078
post embryonic development GO:0009791 2 0.075
cellular amino acid catabolic process GO:0009063 31 0.074
monocarboxylic acid metabolic process GO:0032787 185 0.062
cellular lipid catabolic process GO:0044242 65 0.060
mitochondrion organization GO:0007005 156 0.060
ribonucleoside triphosphate metabolic process GO:0009199 412 0.058
regulation of cellular ketone metabolic process GO:0010565 50 0.058
determination of adult lifespan GO:0008340 2 0.056
transmembrane transport GO:0055085 399 0.056
ribonucleoside monophosphate metabolic process GO:0009161 187 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.050
branched chain amino acid metabolic process GO:0009081 4 0.048
multicellular organismal aging GO:0010259 3 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.044
protein homooligomerization GO:0051260 100 0.044
membrane organization GO:0061024 292 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.044
lipid modification GO:0030258 84 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
cytoplasmic transport GO:0016482 379 0.039
carboxylic acid biosynthetic process GO:0046394 97 0.039
nucleoside monophosphate metabolic process GO:0009123 191 0.039
fatty acid catabolic process GO:0009062 29 0.039
single organism cellular localization GO:1902580 332 0.038
response to oxygen containing compound GO:1901700 369 0.036
purine nucleoside monophosphate metabolic process GO:0009126 186 0.034
single organism membrane organization GO:0044802 268 0.032
lipid catabolic process GO:0016042 84 0.030
positive regulation of hydrolase activity GO:0051345 331 0.030
amine metabolic process GO:0009308 44 0.029
small molecule biosynthetic process GO:0044283 157 0.029
lipid biosynthetic process GO:0008610 177 0.029
organic hydroxy compound metabolic process GO:1901615 147 0.029
coenzyme metabolic process GO:0006732 65 0.029
protein localization to organelle GO:0033365 280 0.028
guanosine containing compound metabolic process GO:1901068 244 0.028
fatty acid oxidation GO:0019395 31 0.028
intracellular protein transport GO:0006886 270 0.027
protein localization to membrane GO:0072657 160 0.027
response to hormone GO:0009725 175 0.027
negative regulation of protein metabolic process GO:0051248 391 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
atp metabolic process GO:0046034 176 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
protein oligomerization GO:0051259 173 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
cellular amine metabolic process GO:0044106 41 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.025
regulation of proteolysis GO:0030162 293 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
ion transmembrane transport GO:0034220 338 0.024
anion transport GO:0006820 161 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.023
protein processing GO:0016485 226 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
carbohydrate metabolic process GO:0005975 207 0.023
cofactor metabolic process GO:0051186 87 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.022
regulation of transferase activity GO:0051338 355 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
vesicle mediated transport GO:0016192 371 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
organophosphate biosynthetic process GO:0090407 163 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
organic acid biosynthetic process GO:0016053 97 0.020
protein maturation GO:0051604 233 0.020
purine containing compound catabolic process GO:0072523 411 0.020
regulation of hormone levels GO:0010817 125 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
negative regulation of transferase activity GO:0051348 124 0.020
organophosphate catabolic process GO:0046434 430 0.020
oogenesis GO:0048477 2 0.019
secretion by cell GO:0032940 226 0.019
response to abiotic stimulus GO:0009628 336 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
defense response GO:0006952 315 0.019
response to lipid GO:0033993 206 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
gtp metabolic process GO:0046039 239 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
establishment of protein localization to organelle GO:0072594 172 0.018
protein targeting GO:0006605 187 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
chemical homeostasis GO:0048878 306 0.018
locomotory behavior GO:0007626 1 0.018
monocarboxylic acid biosynthetic process GO:0072330 67 0.018
memory GO:0007613 3 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
nucleotide catabolic process GO:0009166 408 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
response to nitrogen compound GO:1901698 184 0.017
positive regulation of catabolic process GO:0009896 310 0.017
innate immune response GO:0045087 178 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
cellular response to dna damage stimulus GO:0006974 379 0.016
regulation of secretion GO:0051046 194 0.016
negative regulation of transport GO:0051051 176 0.016
alcohol metabolic process GO:0006066 114 0.016
monocarboxylic acid catabolic process GO:0072329 37 0.016
response to external biotic stimulus GO:0043207 261 0.016
segmentation GO:0035282 4 0.016
positive regulation of transport GO:0051050 336 0.016
endocytosis GO:0006897 159 0.016
cellular protein catabolic process GO:0044257 261 0.016
regulation of peptidase activity GO:0052547 180 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
intracellular protein transmembrane transport GO:0065002 24 0.016
protein catabolic process GO:0030163 325 0.016
immune response GO:0006955 307 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
sulfur compound metabolic process GO:0006790 101 0.016
secretion GO:0046903 254 0.016
nucleoside catabolic process GO:0009164 408 0.016
cellular component morphogenesis GO:0032989 314 0.015
response to oxidative stress GO:0006979 121 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
ras protein signal transduction GO:0007265 73 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
maintenance of location GO:0051235 112 0.015
response to organonitrogen compound GO:0010243 156 0.015
metal ion transport GO:0030001 272 0.014
response to other organism GO:0051707 261 0.014
protein import GO:0017038 130 0.014
regulation of secretion by cell GO:1903530 177 0.014
negative regulation of cell death GO:0060548 345 0.014
endomembrane system organization GO:0010256 196 0.014
ion homeostasis GO:0050801 230 0.014
regulation of kinase activity GO:0043549 314 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
response to inorganic substance GO:0010035 127 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
nervous system development GO:0007399 293 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
intracellular protein transmembrane import GO:0044743 23 0.014
neuromuscular junction development GO:0007528 3 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
female gamete generation GO:0007292 2 0.013
spermatid differentiation GO:0048515 4 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
response to activity GO:0014823 0 0.013
cation homeostasis GO:0055080 189 0.013
response to biotic stimulus GO:0009607 276 0.013
positive regulation of proteolysis GO:0045862 142 0.013
regulation of intracellular transport GO:0032386 195 0.013
response to nutrient levels GO:0031667 81 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
system process GO:0003008 349 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
anion transmembrane transport GO:0098656 76 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
negative regulation of programmed cell death GO:0043069 321 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
response to bacterium GO:0009617 144 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of hormone secretion GO:0046883 57 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
fatty acid beta oxidation GO:0006635 22 0.012
regulation of protein localization GO:0032880 296 0.012
cellular modified amino acid metabolic process GO:0006575 64 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of protein processing GO:0010955 142 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
nitrogen compound transport GO:0071705 191 0.012
biological adhesion GO:0022610 331 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
negative regulation of protein modification process GO:0031400 200 0.012
regulation of protein kinase activity GO:0045859 289 0.012
response to extracellular stimulus GO:0009991 85 0.012
glycerolipid metabolic process GO:0046486 107 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
adult locomotory behavior GO:0008344 1 0.012
neurogenesis GO:0022008 169 0.011
cation transport GO:0006812 331 0.011
lipid localization GO:0010876 106 0.011
spermatid development GO:0007286 4 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of response to external stimulus GO:0032101 222 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
regeneration GO:0031099 4 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
organic anion transport GO:0015711 103 0.011
cytokine production GO:0001816 247 0.011
positive regulation of cell death GO:0010942 263 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
apoptotic signaling pathway GO:0097190 268 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
cell projection organization GO:0030030 252 0.011
cellular cation homeostasis GO:0030003 163 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of cell differentiation GO:0045595 393 0.011
regulation of cellular response to stress GO:0080135 244 0.011
tube closure GO:0060606 3 0.011
regulation of cytokine production GO:0001817 232 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
cellular homeostasis GO:0019725 196 0.010
alcohol biosynthetic process GO:0046165 52 0.010
response to organic cyclic compound GO:0014070 204 0.010
cellular ion homeostasis GO:0006873 168 0.010
monosaccharide metabolic process GO:0005996 74 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
rho protein signal transduction GO:0007266 26 0.010
protein tetramerization GO:0051262 47 0.010
gtp catabolic process GO:0006184 237 0.010
ossification GO:0001503 121 0.010
cellular amide metabolic process GO:0043603 69 0.010
neurological system process GO:0050877 163 0.010
regulation of protein processing GO:0070613 150 0.010

HIBADH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.154
amino acid metabolic disorder DOID:9252 50 0.154
inherited metabolic disorder DOID:655 242 0.154
disease of cellular proliferation DOID:14566 174 0.020
organic acidemia DOID:0060159 14 0.020
sensory system disease DOID:0050155 203 0.020
nervous system disease DOID:863 431 0.020
carbohydrate metabolic disorder DOID:2978 55 0.017
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
eye and adnexa disease DOID:1492 150 0.015
hyperinsulinemic hypoglycemia DOID:13317 7 0.014
eye disease DOID:5614 149 0.013
central nervous system disease DOID:331 186 0.013
musculoskeletal system disease DOID:17 223 0.013
immune system disease DOID:2914 155 0.011
cardiovascular system disease DOID:1287 106 0.011