Homo sapiens

165 known processes

HIF1AN

hypoxia inducible factor 1, alpha subunit inhibitor

(Aliases: FLJ20615,FIH1,DKFZp762F1811,FLJ22027)

HIF1AN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.892
protein ubiquitination GO:0016567 314 0.885
regulation of canonical wnt signaling pathway GO:0060828 88 0.876
canonical wnt signaling pathway GO:0060070 116 0.825
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.750
wnt signaling pathway GO:0016055 156 0.703
protein auto adp ribosylation GO:0070213 4 0.699
glycoprotein metabolic process GO:0009100 110 0.681
positive regulation of telomere maintenance GO:0032206 4 0.599
macromolecule glycosylation GO:0043413 63 0.557
peptidyl threonine modification GO:0018210 45 0.552
positive regulation of dna replication GO:0045740 35 0.545
telomere maintenance via telomere lengthening GO:0010833 9 0.492
glycoprotein biosynthetic process GO:0009101 91 0.490
regulation of wnt signaling pathway GO:0030111 123 0.482
positive regulation of wnt signaling pathway GO:0030177 54 0.471
single organism carbohydrate metabolic process GO:0044723 193 0.464
telomere maintenance via telomerase GO:0007004 8 0.412
regulation of protein catabolic process GO:0042176 155 0.408
protein glycosylation GO:0006486 62 0.398
regulation of telomere maintenance GO:0032204 13 0.379
glycosylation GO:0070085 71 0.347
peptidyl threonine phosphorylation GO:0018107 41 0.341
protein localization to organelle GO:0033365 280 0.334
post embryonic development GO:0009791 2 0.329
positive regulation of protein catabolic process GO:0045732 75 0.316
negative regulation of binding GO:0051100 57 0.310
carbohydrate metabolic process GO:0005975 207 0.307
positive regulation of homeostatic process GO:0032846 47 0.301
regulation of homeostatic process GO:0032844 121 0.294
cellular protein complex assembly GO:0043623 188 0.268
positive regulation of hormone biosynthetic process GO:0046886 4 0.258
protein poly adp ribosylation GO:0070212 3 0.255
response to nitric oxide GO:0071731 4 0.249
dna replication GO:0006260 116 0.232
rna dependent dna replication GO:0006278 16 0.217
response to salt stress GO:0009651 3 0.216
anatomical structure homeostasis GO:0060249 100 0.215
telomere maintenance GO:0000723 32 0.195
carbohydrate derivative biosynthetic process GO:1901137 207 0.192
regulation of dna binding GO:0051101 37 0.187
regulation of binding GO:0051098 111 0.174
protein localization to chromosome GO:0034502 30 0.168
positive regulation of dna metabolic process GO:0051054 73 0.164
protein catabolic process GO:0030163 325 0.162
negative regulation of dna binding GO:0043392 18 0.158
protein adp ribosylation GO:0006471 9 0.157
positive regulation of catabolic process GO:0009896 310 0.154
positive regulation of cellular component organization GO:0051130 376 0.150
regulation of dna metabolic process GO:0051052 153 0.148
positive regulation of chromosome organization GO:2001252 41 0.137
protein polyubiquitination GO:0000209 110 0.126
peptidyl serine phosphorylation GO:0018105 101 0.122
cellular amino acid metabolic process GO:0006520 116 0.115
negative regulation of thymocyte apoptotic process GO:0070244 1 0.111
regulation of dna replication GO:0006275 68 0.097
oogenesis GO:0048477 2 0.092
telomere organization GO:0032200 33 0.087
multicellular organismal aging GO:0010259 3 0.086
retina vasculature development in camera type eye GO:0061298 3 0.080
cellular macromolecular complex assembly GO:0034622 324 0.075
female gamete generation GO:0007292 2 0.075
peptidyl serine modification GO:0018209 106 0.074
monocarboxylic acid metabolic process GO:0032787 185 0.066
cellular macromolecule catabolic process GO:0044265 380 0.062
dopaminergic neuron differentiation GO:0071542 1 0.061
determination of adult lifespan GO:0008340 2 0.058
hemoglobin biosynthetic process GO:0042541 3 0.058
positive regulation of organelle organization GO:0010638 195 0.057
regulation of cellular component biogenesis GO:0044087 281 0.056
regulation of chromosome organization GO:0033044 103 0.055
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.054
response to abiotic stimulus GO:0009628 336 0.051
gas homeostasis GO:0033483 4 0.049
regulation of telomere maintenance via telomerase GO:0032210 6 0.048
chemical homeostasis GO:0048878 306 0.046
vesicle mediated transport GO:0016192 371 0.045
protein localization to chromosome telomeric region GO:0070198 6 0.044
protein processing GO:0016485 226 0.044
oxygen homeostasis GO:0032364 4 0.044
cilium assembly GO:0042384 63 0.043
response to hypoxia GO:0001666 96 0.042
intestinal epithelial cell differentiation GO:0060575 3 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.041
cellular homeostasis GO:0019725 196 0.040
axon cargo transport GO:0008088 2 0.040
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.039
embryonic epithelial tube formation GO:0001838 4 0.038
negative regulation of t cell apoptotic process GO:0070233 4 0.038
protein maturation GO:0051604 233 0.038
thymocyte apoptotic process GO:0070242 2 0.037
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.036
locomotory behavior GO:0007626 1 0.036
associative learning GO:0008306 1 0.035
cytoplasmic transport GO:0016482 379 0.033
defense response GO:0006952 315 0.033
cation transport GO:0006812 331 0.032
circulatory system development GO:0072359 262 0.031
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
regulation of proteolysis GO:0030162 293 0.030
amine metabolic process GO:0009308 44 0.030
response to decreased oxygen levels GO:0036293 96 0.030
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
positive regulation of endopeptidase activity GO:0010950 84 0.030
cell type specific apoptotic process GO:0097285 125 0.029
positive regulation of neural precursor cell proliferation GO:2000179 2 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
secretion by cell GO:0032940 226 0.028
morphogenesis of embryonic epithelium GO:0016331 4 0.028
zymogen activation GO:0031638 70 0.027
growth GO:0040007 202 0.027
microtubule based movement GO:0007018 32 0.027
inorganic ion transmembrane transport GO:0098660 231 0.027
ras protein signal transduction GO:0007265 73 0.026
single organism cellular localization GO:1902580 332 0.026
cellular amine metabolic process GO:0044106 41 0.026
neuroblast proliferation GO:0007405 4 0.025
response to muscle activity GO:0014850 0 0.025
cellular protein catabolic process GO:0044257 261 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
elastin metabolic process GO:0051541 1 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
rhythmic behavior GO:0007622 2 0.025
cation transmembrane transport GO:0098655 238 0.025
regulation of peptidase activity GO:0052547 180 0.025
negative regulation of wnt signaling pathway GO:0030178 69 0.025
single organism membrane organization GO:0044802 268 0.025
hemoglobin metabolic process GO:0020027 3 0.025
cellular chemical homeostasis GO:0055082 180 0.024
regulation of protein localization GO:0032880 296 0.024
positive regulation of transport GO:0051050 336 0.024
neural crest cell development GO:0014032 3 0.024
nucleotide catabolic process GO:0009166 408 0.024
cell projection organization GO:0030030 252 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
circadian behavior GO:0048512 2 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
ubiquitin dependent protein catabolic process GO:0006511 206 0.023
cellular modified amino acid metabolic process GO:0006575 64 0.023
purine nucleotide catabolic process GO:0006195 405 0.022
muscle cell cellular homeostasis GO:0046716 3 0.022
cofactor metabolic process GO:0051186 87 0.022
cellular component morphogenesis GO:0032989 314 0.022
response to auditory stimulus GO:0010996 4 0.022
purine containing compound catabolic process GO:0072523 411 0.022
positive regulation of peptidase activity GO:0010952 88 0.022
mammary gland epithelial cell differentiation GO:0060644 1 0.022
cilium organization GO:0044782 68 0.022
organophosphate catabolic process GO:0046434 430 0.021
response to oxidative stress GO:0006979 121 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
regulation of cellular component movement GO:0051270 334 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
membrane organization GO:0061024 292 0.021
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.020
cytokine production GO:0001816 247 0.020
connective tissue replacement involved in inflammatory response wound healing GO:0002248 1 0.020
microtubule based process GO:0007017 210 0.020
endocytosis GO:0006897 159 0.019
cell cell signaling GO:0007267 155 0.019
ion homeostasis GO:0050801 230 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
embryo development GO:0009790 123 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
ion transmembrane transport GO:0034220 338 0.019
immune response GO:0006955 307 0.019
organelle assembly GO:0070925 176 0.019
epithelium development GO:0060429 227 0.019
regulation of secretion by cell GO:1903530 177 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
protein localization to nucleus GO:0034504 136 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
protein modification by small protein removal GO:0070646 92 0.018
anterograde axon cargo transport GO:0008089 1 0.018
activation of cysteine type endopeptidase activity GO:0097202 57 0.018
visual behavior GO:0007632 2 0.018
apoptotic signaling pathway GO:0097190 268 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
regulation of growth GO:0040008 165 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
memory GO:0007613 3 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
response to radiation GO:0009314 151 0.017
regulation of neuroblast proliferation GO:1902692 3 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
neural tube formation GO:0001841 3 0.017
angiogenesis GO:0001525 147 0.017
nervous system development GO:0007399 293 0.017
positive regulation of proteolysis GO:0045862 142 0.017
angiotensin activated signaling pathway GO:0038166 4 0.017
urogenital system development GO:0001655 65 0.017
segmentation GO:0035282 4 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
response to bacterium GO:0009617 144 0.017
endomembrane system organization GO:0010256 196 0.017
blastoderm segmentation GO:0007350 2 0.017
response to nitrogen compound GO:1901698 184 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
response to oxygen containing compound GO:1901700 369 0.016
sensory perception of pain GO:0019233 4 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.016
secretion GO:0046903 254 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
ventricular septum morphogenesis GO:0060412 3 0.016
regulation of cytokine production GO:0001817 232 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
circadian sleep wake cycle GO:0042745 2 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
response to oxygen levels GO:0070482 100 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
neuromuscular junction development GO:0007528 3 0.016
regulation of hormone levels GO:0010817 125 0.016
positive regulation of secretion GO:0051047 116 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
protein targeting GO:0006605 187 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
interspecies interaction between organisms GO:0044419 156 0.015
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 5 0.015
positive regulation of telomere maintenance via telomerase GO:0032212 2 0.015
regulation of cell cycle GO:0051726 393 0.015
maintenance of location GO:0051235 112 0.015
visual learning GO:0008542 1 0.015
negative regulation of organelle organization GO:0010639 126 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
alpha amino acid metabolic process GO:1901605 72 0.015
embryonic placenta development GO:0001892 1 0.015
cardiac ventricle development GO:0003231 23 0.015
glial cell migration GO:0008347 4 0.015
organelle localization GO:0051640 84 0.015
regulation of secretion GO:0051046 194 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
response to reactive oxygen species GO:0000302 61 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
wound healing involved in inflammatory response GO:0002246 2 0.015
positive regulation of neuroblast proliferation GO:0002052 2 0.015
glycosyl compound catabolic process GO:1901658 413 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
histone modification GO:0016570 251 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of peptide transport GO:0090087 62 0.014
heart development GO:0007507 95 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
ameboidal type cell migration GO:0001667 135 0.014
pancreas development GO:0031016 19 0.014
amide transport GO:0042886 76 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
cellular ion homeostasis GO:0006873 168 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of multi organism process GO:0043900 157 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
nitrogen compound transport GO:0071705 191 0.013
cellular response to external stimulus GO:0071496 111 0.013
organelle fission GO:0048285 149 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
hormone metabolic process GO:0042445 61 0.013
left right pattern formation GO:0060972 2 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
skeletal system development GO:0001501 79 0.013
protein deubiquitination GO:0016579 79 0.013
negative regulation of blood circulation GO:1903523 4 0.013
single organism reproductive process GO:0044702 98 0.013
trabecula morphogenesis GO:0061383 2 0.013
spermatid development GO:0007286 4 0.013
blood vessel morphogenesis GO:0048514 162 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
kidney development GO:0001822 53 0.013
myosin filament assembly GO:0031034 2 0.013
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.013
golgi vesicle transport GO:0048193 80 0.013
cofactor biosynthetic process GO:0051188 31 0.013
positive regulation of apoptotic process GO:0043065 246 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
neural crest cell migration GO:0001755 2 0.012
muscle organ development GO:0007517 56 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
vasculature development GO:0001944 181 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
sleep GO:0030431 2 0.012
cation homeostasis GO:0055080 189 0.012
regulation of neurotransmitter secretion GO:0046928 3 0.012
mitotic nuclear division GO:0007067 119 0.012
4 hydroxyproline metabolic process GO:0019471 5 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
epithelium migration GO:0090132 119 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
cytoskeleton dependent intracellular transport GO:0030705 21 0.012
tripartite regional subdivision GO:0007351 2 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
oocyte development GO:0048599 1 0.012
dephosphorylation GO:0016311 209 0.012
pattern specification process GO:0007389 43 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
nucleoside catabolic process GO:0009164 408 0.012
intracellular protein transport GO:0006886 270 0.012
reproductive process GO:0022414 106 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
transmembrane transport GO:0055085 399 0.012
cellular cation homeostasis GO:0030003 163 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
viral process GO:0016032 146 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
dna repair GO:0006281 198 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
spermatid differentiation GO:0048515 4 0.012
cellular response to radiation GO:0071478 65 0.012
protein secretion GO:0009306 98 0.011
regulation of cell division GO:0051302 116 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
blood circulation GO:0008015 113 0.011
cellular response to oxidative stress GO:0034599 85 0.011
peptide transport GO:0015833 74 0.011
regulation of protein maturation GO:1903317 150 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
positive regulation of cytokine production GO:0001819 167 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
regulation of cell migration GO:0030334 289 0.011
lipid metabolic process GO:0006629 381 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
rho protein signal transduction GO:0007266 26 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
actin mediated cell contraction GO:0070252 12 0.011
trachea development GO:0060438 1 0.011
peripheral nervous system development GO:0007422 2 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
regulation of transferase activity GO:0051338 355 0.011
protein acylation GO:0043543 138 0.011
regeneration GO:0031099 4 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
regulation of response to external stimulus GO:0032101 222 0.011
rna interference GO:0016246 4 0.011
microtubule based transport GO:0010970 21 0.011
cell development GO:0048468 328 0.011
cellular lipid metabolic process GO:0044255 303 0.011
chromatin modification GO:0016568 298 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
adult locomotory behavior GO:0008344 1 0.011
negative regulation of developmental process GO:0051093 247 0.011
mitotic cell cycle process GO:1903047 286 0.011
protein hydroxylation GO:0018126 9 0.011
primary neural tube formation GO:0014020 3 0.011
regulation of viral process GO:0050792 103 0.010
positive regulation of cell cycle GO:0045787 140 0.010
inflammatory response GO:0006954 79 0.010
protein oligomerization GO:0051259 173 0.010
neurological system process GO:0050877 163 0.010
actin filament based process GO:0030029 224 0.010
blood vessel development GO:0001568 172 0.010
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.010
circadian sleep wake cycle sleep GO:0050802 2 0.010
metal ion transport GO:0030001 272 0.010
cell projection assembly GO:0030031 126 0.010
negative regulation of proteolysis GO:0045861 132 0.010
circadian sleep wake cycle process GO:0022410 2 0.010
protein polymerization GO:0051258 71 0.010
multi organism cellular process GO:0044764 156 0.010
positive regulation of protein transport GO:0051222 135 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
inner ear morphogenesis GO:0042472 4 0.010

HIF1AN disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.031
nephronophthisis DOID:12712 13 0.020
sensory system disease DOID:0050155 203 0.020
eye and adnexa disease DOID:1492 150 0.020
nervous system disease DOID:863 431 0.020
central nervous system disease DOID:331 186 0.018
musculoskeletal system disease DOID:17 223 0.017
eye disease DOID:5614 149 0.015
mitochondrial metabolism disease DOID:700 29 0.012
inherited metabolic disorder DOID:655 242 0.012
neurodegenerative disease DOID:1289 102 0.012
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
retinal disease DOID:5679 118 0.010
cardiovascular system disease DOID:1287 106 0.010