Homo sapiens

187 known processes

HIPK2

homeodomain interacting protein kinase 2

(Aliases: DKFZp686K02111,FLJ23711,PRO0593)

HIPK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 1.000
Mouse
positive regulation of cell death GO:0010942 263 0.983
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.978
Mouse
locomotory behavior GO:0007626 1 0.971
Mouse
response to transforming growth factor beta GO:0071559 94 0.967
nucleoside triphosphate metabolic process GO:0009141 422 0.962
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.957
circulatory system process GO:0003013 113 0.948
hair follicle morphogenesis GO:0031069 2 0.947
regulation of male gonad development GO:2000018 4 0.942
regulation of cell migration GO:0030334 289 0.937
zymogen activation GO:0031638 70 0.934
apoptotic signaling pathway GO:0097190 268 0.933
Human Mouse
negative regulation of cellular component organization GO:0051129 235 0.933
ribonucleoside triphosphate metabolic process GO:0009199 412 0.932
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.932
regulation of synaptic plasticity GO:0048167 3 0.931
oxidation reduction process GO:0055114 396 0.929
negative regulation of phagocytosis engulfment GO:0060101 1 0.924
positive regulation of cellular component biogenesis GO:0044089 158 0.922
positive regulation of developmental process GO:0051094 314 0.922
muscle organ development GO:0007517 56 0.911
hematopoietic or lymphoid organ development GO:0048534 186 0.903
embryonic camera type eye morphogenesis GO:0048596 2 0.899
Mouse
positive regulation of apoptotic process involved in morphogenesis GO:1902339 1 0.894
regulation of glycogen metabolic process GO:0070873 15 0.887
purine ribonucleoside catabolic process GO:0046130 398 0.882
response to abiotic stimulus GO:0009628 336 0.882
Fly
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 1 0.870
purine ribonucleoside metabolic process GO:0046128 437 0.869
epidermis morphogenesis GO:0048730 3 0.862
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.861
ribonucleoside catabolic process GO:0042454 406 0.856
regulation of phagocytosis engulfment GO:0060099 2 0.855
neural crest cell development GO:0014032 3 0.852
visual learning GO:0008542 1 0.847
blood circulation GO:0008015 113 0.840
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.836
sensory perception of pain GO:0019233 4 0.836
multicellular organismal response to stress GO:0033555 1 0.835
definitive hemopoiesis GO:0060216 2 0.830
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.825
post embryonic development GO:0009791 2 0.821
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.817
negative regulation of cell death GO:0060548 345 0.814
Human Mouse
cellular response to growth factor stimulus GO:0071363 197 0.812
response to oxygen levels GO:0070482 100 0.811
ossification GO:0001503 121 0.797
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.792
purine nucleoside triphosphate metabolic process GO:0009144 412 0.792
osteoblast differentiation GO:0001649 92 0.788
cellular response to dna damage stimulus GO:0006974 379 0.783
hippo signaling GO:0035329 20 0.783
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.771
interspecies interaction between organisms GO:0044419 156 0.762
cytoplasmic transport GO:0016482 379 0.741
negative regulation of nfat protein import into nucleus GO:0051534 2 0.737
response to growth factor GO:0070848 205 0.734
guanosine containing compound metabolic process GO:1901068 244 0.733
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.727
embryonic eye morphogenesis GO:0048048 2 0.726
Mouse
cardiac ventricle formation GO:0003211 2 0.718
embryonic camera type eye development GO:0031076 2 0.718
Mouse
secretion by cell GO:0032940 226 0.714
negative regulation of locomotion GO:0040013 118 0.709
startle response GO:0001964 3 0.705
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.702
regulation of nucleoside metabolic process GO:0009118 209 0.691
cardiac right ventricle formation GO:0003219 1 0.687
protein sumoylation GO:0016925 25 0.681
cellular carbohydrate metabolic process GO:0044262 84 0.679
gtp catabolic process GO:0006184 237 0.675
viral life cycle GO:0019058 132 0.671
positive regulation of cellular component organization GO:0051130 376 0.669
cellular response to ionizing radiation GO:0071479 32 0.667
purine nucleoside triphosphate catabolic process GO:0009146 392 0.666
negative regulation of organelle organization GO:0010639 126 0.665
defense response GO:0006952 315 0.661
hemopoiesis GO:0030097 180 0.658
hexose metabolic process GO:0019318 55 0.654
regulation of cellular component size GO:0032535 82 0.652
cell fate determination GO:0001709 3 0.651
ribonucleoside triphosphate catabolic process GO:0009203 391 0.650
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.647
Mouse
regulation of protein import into nucleus GO:0042306 78 0.644
positive regulation of tooth mineralization GO:0070172 2 0.642
neuron differentiation GO:0030182 138 0.640
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.639
ameboidal type cell migration GO:0001667 135 0.637
nucleotide catabolic process GO:0009166 408 0.634
cerebellum development GO:0021549 2 0.630
muscle structure development GO:0061061 98 0.625
negative regulation of cell motility GO:2000146 104 0.617
energy derivation by oxidation of organic compounds GO:0015980 43 0.613
regulation of locomotion GO:0040012 329 0.612
steroid metabolic process GO:0008202 94 0.603
negative regulation of histone acetylation GO:0035067 6 0.602
pharynx development GO:0060465 1 0.602
glycosyl compound catabolic process GO:1901658 413 0.597
activation of cysteine type endopeptidase activity GO:0097202 57 0.585
negative regulation of transport GO:0051051 176 0.585
response to hypoxia GO:0001666 96 0.583
signal transduction by p53 class mediator GO:0072331 72 0.582
nervous system development GO:0007399 293 0.580
Mouse
behavior GO:0007610 112 0.578
Mouse
somitogenesis GO:0001756 2 0.572
tissue morphogenesis GO:0048729 96 0.569
Mouse
rho protein signal transduction GO:0007266 26 0.567
protein modification by small protein removal GO:0070646 92 0.563
positive regulation of male gonad development GO:2000020 3 0.559
nucleocytoplasmic transport GO:0006913 176 0.551
blood vessel development GO:0001568 172 0.544
positive regulation of apoptotic process GO:0043065 246 0.537
histone modification GO:0016570 251 0.536
regulation of osteoblast differentiation GO:0045667 38 0.531
purine containing compound catabolic process GO:0072523 411 0.528
cell development GO:0048468 328 0.527
calcium ion transport GO:0006816 147 0.526
endocardial cushion development GO:0003197 3 0.520
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.516
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.515
regulation of cell motility GO:2000145 299 0.511
regulation of proteolysis GO:0030162 293 0.511
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.511
gtp metabolic process GO:0046039 239 0.507
positive regulation of dna templated transcription elongation GO:0032786 18 0.502
positive regulation of cellular catabolic process GO:0031331 284 0.501
endomembrane system organization GO:0010256 196 0.501
regulation of system process GO:0044057 101 0.498
dna repair GO:0006281 198 0.497
regulation of viral transcription GO:0046782 34 0.497
positive regulation of viral process GO:0048524 37 0.494
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.492
system process GO:0003008 349 0.489
regulation of ossification GO:0030278 58 0.482
bile acid metabolic process GO:0008206 14 0.476
common partner smad protein phosphorylation GO:0007182 3 0.473
negative regulation of phagocytosis GO:0050765 4 0.473
nucleoside phosphate catabolic process GO:1901292 412 0.471
response to radiation GO:0009314 151 0.471
cellular component morphogenesis GO:0032989 314 0.469
macromolecule deacylation GO:0098732 41 0.468
carbohydrate metabolic process GO:0005975 207 0.464
embryo development GO:0009790 123 0.462
Mouse
generation of precursor metabolites and energy GO:0006091 68 0.460
multi organism cellular process GO:0044764 156 0.457
regulation of cell development GO:0060284 161 0.457
cell type specific apoptotic process GO:0097285 125 0.456
Human Mouse
negative regulation of chromosome organization GO:2001251 48 0.453
protein processing GO:0016485 226 0.452
regulation of cellular component movement GO:0051270 334 0.451
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.451
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.449
protein ubiquitination GO:0016567 314 0.448
regulation of neuron differentiation GO:0045664 70 0.444
protein maturation GO:0051604 233 0.442
pituitary gland development GO:0021983 2 0.442
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.440
regulation of protein transport GO:0051223 213 0.437
negative regulation of protein modification process GO:0031400 200 0.435
negative regulation of cellular amine metabolic process GO:0033239 3 0.435
regulation of peptidase activity GO:0052547 180 0.434
histone h3 acetylation GO:0043966 45 0.433
guanosine containing compound catabolic process GO:1901069 239 0.430
regulation of histone modification GO:0031056 47 0.425
cellular response to organic cyclic compound GO:0071407 127 0.419
regulation of generation of precursor metabolites and energy GO:0043467 27 0.415
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.412
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.410
histone methylation GO:0016571 60 0.407
regulation of rho protein signal transduction GO:0035023 79 0.404
proteasomal protein catabolic process GO:0010498 176 0.402
regulation of endopeptidase activity GO:0052548 170 0.398
cardiovascular system development GO:0072358 262 0.396
regulation of cysteine type endopeptidase activity GO:2000116 127 0.395
cellular protein catabolic process GO:0044257 261 0.390
cation transport GO:0006812 331 0.389
membrane organization GO:0061024 292 0.388
embryonic camera type eye formation GO:0060900 2 0.386
positive regulation of multi organism process GO:0043902 56 0.382
circadian behavior GO:0048512 2 0.378
regulation of dna templated transcription elongation GO:0032784 23 0.377
cellular amine metabolic process GO:0044106 41 0.370
vitamin d receptor signaling pathway GO:0070561 4 0.369
cellular response to external stimulus GO:0071496 111 0.369
regulation of intracellular transport GO:0032386 195 0.368
trophectodermal cell differentiation GO:0001829 3 0.368
positive regulation of protein sumoylation GO:0033235 7 0.366
positive regulation of ras gtpase activity GO:0032320 117 0.365
multi organism metabolic process GO:0044033 41 0.364
mitotic g1 dna damage checkpoint GO:0031571 17 0.363
tube morphogenesis GO:0035239 95 0.361
regulation of actin filament polymerization GO:0030833 50 0.360
organophosphate catabolic process GO:0046434 430 0.356
smooth muscle cell proliferation GO:0048659 28 0.355
immune system development GO:0002520 195 0.351
regulation of polysaccharide biosynthetic process GO:0032885 20 0.351
n terminal protein amino acid modification GO:0031365 13 0.350
chromatin assembly or disassembly GO:0006333 78 0.349
ras protein signal transduction GO:0007265 73 0.346
regulation of gtp catabolic process GO:0033124 180 0.342
lipid localization GO:0010876 106 0.342
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.341
nuclear transport GO:0051169 179 0.341
negative regulation of cell migration GO:0030336 102 0.341
mitotic cell cycle process GO:1903047 286 0.339
camera type eye development GO:0043010 25 0.337
Mouse
regulation of ras gtpase activity GO:0032318 128 0.333
organ formation GO:0048645 3 0.333
catecholamine secretion GO:0050432 1 0.333
negative regulation of protein acetylation GO:1901984 11 0.332
protein deacylation GO:0035601 39 0.331
protein modification by small protein conjugation GO:0032446 342 0.330
regulation of viral process GO:0050792 103 0.328
microtubule based process GO:0007017 210 0.327
response to virus GO:0009615 126 0.326
secretion GO:0046903 254 0.322
positive regulation of protein complex assembly GO:0031334 86 0.322
protein import into nucleus GO:0006606 104 0.321
apoptotic process involved in morphogenesis GO:0060561 3 0.319
chromatin modification GO:0016568 298 0.317
monosaccharide metabolic process GO:0005996 74 0.314
regulation of mhc class i biosynthetic process GO:0045343 4 0.313
cell differentiation in spinal cord GO:0021515 1 0.311
cellular polysaccharide biosynthetic process GO:0033692 21 0.311
long term synaptic potentiation GO:0060291 1 0.309
mesenchymal cell development GO:0014031 50 0.309
positive regulation of apoptotic signaling pathway GO:2001235 70 0.309
cellular response to cytokine stimulus GO:0071345 181 0.308
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.307
regulation of anatomical structure size GO:0090066 101 0.304
regulation of gtpase activity GO:0043087 180 0.304
regulation of kinase activity GO:0043549 314 0.301
glucan metabolic process GO:0044042 22 0.300
nucleoside triphosphate catabolic process GO:0009143 394 0.299
homeostasis of number of cells GO:0048872 40 0.296
maintenance of location GO:0051235 112 0.294
memory GO:0007613 3 0.294
negative regulation of protein transport GO:0051224 75 0.294
segmentation GO:0035282 4 0.293
lymphocyte proliferation GO:0046651 70 0.293
negative regulation of cellular component movement GO:0051271 106 0.290
epidermis development GO:0008544 59 0.290
apoptotic mitochondrial changes GO:0008637 57 0.290
viral transcription GO:0019083 35 0.288
regulation of nucleotide catabolic process GO:0030811 205 0.288
regulation of cell differentiation GO:0045595 393 0.287
Zebrafish
polysaccharide metabolic process GO:0005976 33 0.284
hormone transport GO:0009914 68 0.283
response to ionizing radiation GO:0010212 65 0.282
actin filament based process GO:0030029 224 0.279
embryonic placenta development GO:0001892 1 0.278
regulation of cell cycle phase transition GO:1901987 126 0.277
blood vessel morphogenesis GO:0048514 162 0.276
modification dependent macromolecule catabolic process GO:0043632 212 0.276
cellular response to hypoxia GO:0071456 51 0.275
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.274
intracellular bile acid receptor signaling pathway GO:0038185 1 0.273
cellular response to abiotic stimulus GO:0071214 117 0.273
viral gene expression GO:0019080 35 0.271
single organism nuclear import GO:1902593 104 0.269
apoptotic process involved in mammary gland involution GO:0060057 1 0.266
negative regulation of chromatin modification GO:1903309 21 0.265
regulation of purine nucleotide catabolic process GO:0033121 205 0.265
positive regulation of synaptic transmission GO:0050806 4 0.264
digestive tract morphogenesis GO:0048546 56 0.264
regulation of growth GO:0040008 165 0.261
cell activation GO:0001775 213 0.261
ethanolamine containing compound metabolic process GO:0042439 26 0.261
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.258
Mouse
protein targeting to nucleus GO:0044744 104 0.252
lens development in camera type eye GO:0002088 2 0.248
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.247
chordate embryonic development GO:0043009 34 0.247
cellular polysaccharide metabolic process GO:0044264 27 0.243
cellular chemical homeostasis GO:0055082 180 0.243
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.242
single organism membrane organization GO:0044802 268 0.240
single organism cellular localization GO:1902580 332 0.238
chromatin organization GO:0006325 351 0.238
response to gamma radiation GO:0010332 14 0.236
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.232
associative learning GO:0008306 1 0.232
heart process GO:0003015 62 0.231
regulation of cellular ketone metabolic process GO:0010565 50 0.231
pml body organization GO:0030578 2 0.230
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.228
ribonucleoside monophosphate metabolic process GO:0009161 187 0.226
cellular response to alcohol GO:0097306 29 0.225
regulation of establishment of protein localization GO:0070201 242 0.220
protein acetylation GO:0006473 116 0.219
developmental growth GO:0048589 48 0.217
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.215
Mouse
positive regulation of viral transcription GO:0050434 13 0.212
protein localization to organelle GO:0033365 280 0.212
cellular lipid metabolic process GO:0044255 303 0.210
regulation of small gtpase mediated signal transduction GO:0051056 156 0.210
ubiquitin dependent protein catabolic process GO:0006511 206 0.210
regulation of rho gtpase activity GO:0032319 66 0.209
hindbrain development GO:0030902 3 0.208
purine ribonucleotide catabolic process GO:0009154 404 0.208
purine nucleotide catabolic process GO:0006195 405 0.208
aortic valve development GO:0003176 3 0.208
meiotic chromosome segregation GO:0045132 4 0.206
regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0000117 1 0.206
establishment of protein localization to organelle GO:0072594 172 0.206
neurological system process GO:0050877 163 0.205
eye development GO:0001654 42 0.205
Mouse Fly
myoblast fusion GO:0007520 1 0.205
actin filament organization GO:0007015 128 0.204
positive regulation of programmed cell death GO:0043068 249 0.204
genetic imprinting GO:0071514 1 0.204
activation of jnkk activity GO:0007256 1 0.204
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.203
organ morphogenesis GO:0009887 147 0.202
Mouse Fly
cellular response to decreased oxygen levels GO:0036294 51 0.200
inner ear morphogenesis GO:0042472 4 0.199
amine metabolic process GO:0009308 44 0.199
regulation of cell growth GO:0001558 135 0.198
peptidyl lysine acetylation GO:0018394 101 0.197
regulation of transferase activity GO:0051338 355 0.195
regulation of signal transduction by p53 class mediator GO:1901796 26 0.194
negative regulation of myotube differentiation GO:0010832 4 0.193
intracellular protein transport GO:0006886 270 0.191
mitochondrion organization GO:0007005 156 0.191
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.191
androgen receptor signaling pathway GO:0030521 34 0.190
endocrine system development GO:0035270 26 0.190
peripheral nervous system development GO:0007422 2 0.190
skin morphogenesis GO:0043589 6 0.189
positive regulation of cellular amine metabolic process GO:0033240 7 0.189
visual behavior GO:0007632 2 0.189
cell cycle g2 m phase transition GO:0044839 43 0.188
regulation of defense response to virus by host GO:0050691 22 0.188
regulation of peptidyl lysine acetylation GO:2000756 22 0.186
regulation of hormone levels GO:0010817 125 0.183
glycogen metabolic process GO:0005977 22 0.183
positive regulation of protein phosphorylation GO:0001934 313 0.183
Mouse
vesicle mediated transport GO:0016192 371 0.183
cell division GO:0051301 168 0.182
embryonic organ development GO:0048568 36 0.181
Mouse
regulation of neuronal synaptic plasticity GO:0048168 1 0.180
regulation of organ morphogenesis GO:2000027 24 0.177
negative regulation of smoothened signaling pathway GO:0045879 3 0.176
gastrulation GO:0007369 51 0.175
negative regulation of apoptotic process GO:0043066 316 0.175
Human Mouse
cellular response to nitrogen compound GO:1901699 144 0.173
positive regulation of odontogenesis GO:0042482 3 0.172
skeletal system development GO:0001501 79 0.172
positive regulation of chromosome organization GO:2001252 41 0.171
response to toxic substance GO:0009636 37 0.170
regulation of leukocyte differentiation GO:1902105 61 0.169
regulation of nucleotide metabolic process GO:0006140 269 0.168
second messenger mediated signaling GO:0019932 78 0.167
cartilage development GO:0051216 31 0.166
i kappab kinase nf kappab signaling GO:0007249 166 0.166
cardiac chamber formation GO:0003207 2 0.164
regulation of apoptotic signaling pathway GO:2001233 175 0.164
negative regulation of protein metabolic process GO:0051248 391 0.164
modification dependent protein catabolic process GO:0019941 209 0.163
positive regulation of nervous system development GO:0051962 54 0.163
divalent metal ion transport GO:0070838 152 0.162
sensory organ development GO:0007423 52 0.161
Mouse Fly
regulation of mitotic cell cycle GO:0007346 189 0.160
neuron apoptotic process GO:0051402 39 0.159
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.159
Fly
regulation of cell cycle GO:0051726 393 0.157
purine nucleoside catabolic process GO:0006152 398 0.156
regulation of response to external stimulus GO:0032101 222 0.155
negative regulation of angiogenesis GO:0016525 39 0.154
neuron death GO:0070997 65 0.154
Mouse
growth GO:0040007 202 0.154
Fly
atp synthesis coupled electron transport GO:0042773 4 0.154
positive regulation of endopeptidase activity GO:0010950 84 0.152
positive regulation of catabolic process GO:0009896 310 0.151
positive regulation of proteolysis GO:0045862 142 0.150
regulation of purine nucleotide metabolic process GO:1900542 264 0.150
eyelid development in camera type eye GO:0061029 2 0.149
organic hydroxy compound metabolic process GO:1901615 147 0.149
regulation of protein maturation GO:1903317 150 0.148
dna damage response signal transduction resulting in transcription GO:0042772 12 0.148
nerve development GO:0021675 4 0.147
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.147
positive regulation of actin filament polymerization GO:0030838 38 0.147
carbohydrate biosynthetic process GO:0016051 42 0.146
purine nucleoside monophosphate metabolic process GO:0009126 186 0.145
protein deacetylation GO:0006476 38 0.145
defense response to other organism GO:0098542 129 0.145
intracellular receptor signaling pathway GO:0030522 104 0.145
response to acid chemical GO:0001101 66 0.145
positive regulation of nucleotide metabolic process GO:0045981 230 0.143
regulation of jak stat cascade GO:0046425 44 0.143
epithelial cell differentiation GO:0030855 141 0.142
Zebrafish
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.142
regulation of actin filament based process GO:0032970 141 0.142
connective tissue development GO:0061448 39 0.142
epithelium development GO:0060429 227 0.141
Zebrafish
negative regulation of cytoplasmic transport GO:1903650 46 0.141
regulation of chromatin modification GO:1903308 51 0.141
negative regulation of histone modification GO:0031057 19 0.140
positive regulation of mitotic cell cycle GO:0045931 60 0.139
atrioventricular valve development GO:0003171 3 0.138
branching morphogenesis of an epithelial tube GO:0048754 19 0.138
protein polyubiquitination GO:0000209 110 0.138
histone deacetylation GO:0016575 32 0.137
regulation of histone acetylation GO:0035065 19 0.137
nucleoside catabolic process GO:0009164 408 0.137
protein oligomerization GO:0051259 173 0.137
nuclear import GO:0051170 106 0.136
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.136
spindle organization GO:0007051 53 0.136
leukocyte differentiation GO:0002521 98 0.135
glucose homeostasis GO:0042593 31 0.134
sensory perception GO:0007600 103 0.134
positive regulation of peptidase activity GO:0010952 88 0.134
erythrocyte differentiation GO:0030218 28 0.134
regulation of protein localization GO:0032880 296 0.134
determination of adult lifespan GO:0008340 2 0.134
Worm
nucleoside monophosphate metabolic process GO:0009123 191 0.133
epithelial tube morphogenesis GO:0060562 38 0.132
regulation of apoptotic process involved in morphogenesis GO:1902337 1 0.132
protein localization to nucleus GO:0034504 136 0.132
regulation of secretion by cell GO:1903530 177 0.131
central nervous system development GO:0007417 123 0.131
protein alkylation GO:0008213 74 0.131
response to oxidative stress GO:0006979 121 0.130
response to decreased oxygen levels GO:0036293 96 0.129
regulation of protein kinase activity GO:0045859 289 0.129
regulation of response to dna damage stimulus GO:2001020 94 0.129
cellular response to oxygen levels GO:0071453 55 0.128
negative regulation of bile acid biosynthetic process GO:0070858 3 0.128
mitotic cell cycle GO:0000278 326 0.128
dna packaging GO:0006323 77 0.127
intrinsic apoptotic signaling pathway GO:0097193 127 0.127
Mouse
regulation of cell division GO:0051302 116 0.127
protein methylation GO:0006479 74 0.127
cellular response to xenobiotic stimulus GO:0071466 29 0.126
regulation of cellular amine metabolic process GO:0033238 11 0.126
metal ion transport GO:0030001 272 0.124
monoamine transport GO:0015844 10 0.124
regulation of cellular amino acid metabolic process GO:0006521 6 0.123
negative regulation of multicellular organismal process GO:0051241 317 0.123
androgen biosynthetic process GO:0006702 3 0.123
regulation of polysaccharide metabolic process GO:0032881 21 0.123
lymphocyte activation GO:0046649 133 0.123
cellular response to radiation GO:0071478 65 0.122
regulation of cell projection organization GO:0031344 107 0.122
positive regulation of hydrolase activity GO:0051345 331 0.122
regulation of defense response GO:0031347 154 0.122
rac protein signal transduction GO:0016601 12 0.122
negative regulation of epithelial cell proliferation GO:0050680 48 0.121
muscle tissue development GO:0060537 62 0.121
protein destabilization GO:0031648 12 0.121
multicellular organismal aging GO:0010259 3 0.121
Worm
cell proliferation involved in heart valve development GO:2000793 1 0.120
cellular amino acid metabolic process GO:0006520 116 0.120
nuclear division GO:0000280 128 0.120
regulation of blood pressure GO:0008217 30 0.119
keratinocyte differentiation GO:0030216 36 0.119
skin development GO:0043588 76 0.119
cellular ketone metabolic process GO:0042180 80 0.117
positive regulation of protein polymerization GO:0032273 45 0.116
fear response GO:0042596 0 0.116
regulation of neuron projection development GO:0010975 57 0.116
cytokinesis GO:0000910 96 0.116
positive regulation of glucose metabolic process GO:0010907 12 0.116
oxidative phosphorylation GO:0006119 10 0.115
steroid biosynthetic process GO:0006694 46 0.115
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.114
lipid storage GO:0019915 28 0.114
keratinocyte proliferation GO:0043616 17 0.113
histone acetylation GO:0016573 93 0.113
endodermal cell fate commitment GO:0001711 4 0.113
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.112
neuroblast proliferation GO:0007405 4 0.112
regulation of actin cytoskeleton organization GO:0032956 116 0.111
negative regulation of transferase activity GO:0051348 124 0.111
morphogenesis of a branching structure GO:0001763 21 0.111
regulation of cytoplasmic transport GO:1903649 149 0.111
negative regulation of cellular senescence GO:2000773 5 0.110
cell cycle phase transition GO:0044770 173 0.110
negative regulation of apoptotic signaling pathway GO:2001234 97 0.110
regulation of viral release from host cell GO:1902186 20 0.109
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.109
regulation of chromatin organization GO:1902275 56 0.109
sex determination GO:0007530 3 0.108
positive regulation of cell differentiation GO:0045597 211 0.108

HIPK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
chromosomal disease DOID:0080014 16 0.706
cancer DOID:162 167 0.657
disease of cellular proliferation DOID:14566 174 0.657
disease of mental health DOID:150 70 0.556
organ system cancer DOID:0050686 164 0.504
gonadal dysgenesis DOID:14447 8 0.142
immune system disease DOID:2914 155 0.108
hematopoietic system disease DOID:74 100 0.108