Homo sapiens

80 known processes

HIST1H4D

histone cluster 1, H4d

(Aliases: H4FB,dJ221C16.9,H4/b)

HIST1H4D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication dependent nucleosome assembly GO:0006335 32 0.999
negative regulation of megakaryocyte differentiation GO:0045653 16 0.996
dna replication dependent nucleosome organization GO:0034723 32 0.994
nucleosome assembly GO:0006334 50 0.991
dna replication independent nucleosome organization GO:0034724 27 0.990
dna replication independent nucleosome assembly GO:0006336 27 0.987
chromatin assembly GO:0031497 61 0.978
chromatin assembly or disassembly GO:0006333 78 0.973
nucleosome organization GO:0034728 66 0.949
protein dna complex assembly GO:0065004 64 0.848
dna packaging GO:0006323 77 0.806
dna conformation change GO:0071103 113 0.801
regulation of megakaryocyte differentiation GO:0045652 22 0.793
chromatin organization GO:0006325 351 0.761
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.720
histone h3 k79 methylation GO:0034729 2 0.716
Yeast
negative regulation of myeloid cell differentiation GO:0045638 42 0.684
protein dna complex subunit organization GO:0071824 80 0.683
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.675
Yeast
megakaryocyte differentiation GO:0030219 25 0.589
regulation of myeloid cell differentiation GO:0045637 81 0.561
histone methylation GO:0016571 60 0.452
Yeast
myeloid cell differentiation GO:0030099 117 0.418
hematopoietic progenitor cell differentiation GO:0002244 38 0.410
cellular macromolecular complex assembly GO:0034622 324 0.364
negative regulation of hematopoietic progenitor cell differentiation GO:1901533 18 0.326
macromolecule methylation GO:0043414 97 0.321
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.310
dna repair GO:0006281 198 0.305
protein alkylation GO:0008213 74 0.274
Yeast
regulation of cell differentiation GO:0045595 393 0.273
negative regulation of developmental process GO:0051093 247 0.264
protein methylation GO:0006479 74 0.258
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 284 0.250
Yeast
immune system development GO:0002520 195 0.244
hematopoietic or lymphoid organ development GO:0048534 186 0.240
negative regulation of immune system process GO:0002683 136 0.239
negative regulation of multicellular organismal process GO:0051241 317 0.235
methylation GO:0032259 106 0.202
Yeast
negative regulation of cell differentiation GO:0045596 171 0.192
regulation of gene silencing GO:0060968 24 0.189
chromatin modification GO:0016568 298 0.188
Yeast
gene silencing GO:0016458 49 0.187
Yeast
hemopoiesis GO:0030097 180 0.169
histone modification GO:0016570 251 0.166
Yeast
histone lysine methylation GO:0034968 50 0.137
Yeast
covalent chromatin modification GO:0016569 254 0.096
Yeast
cell cycle checkpoint GO:0000075 117 0.095
mrna metabolic process GO:0016071 175 0.079
negative regulation of gene expression epigenetic GO:0045814 19 0.070
Yeast
protein complex disassembly GO:0043241 52 0.068
post embryonic development GO:0009791 2 0.068
dna damage checkpoint GO:0000077 68 0.066
regulation of gene expression epigenetic GO:0040029 73 0.064
Yeast
cellular component disassembly GO:0022411 92 0.063
response to uv GO:0009411 73 0.057
response to abiotic stimulus GO:0009628 336 0.052
cellular response to uv GO:0034644 32 0.052
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
mrna processing GO:0006397 133 0.048
response to radiation GO:0009314 151 0.046
dna integrity checkpoint GO:0031570 71 0.045
cellular response to radiation GO:0071478 65 0.043
cellular response to abiotic stimulus GO:0071214 117 0.043
chromatin silencing GO:0006342 12 0.043
Yeast
response to light stimulus GO:0009416 87 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
rna processing GO:0006396 255 0.042
cellular macromolecule catabolic process GO:0044265 380 0.039
protein maturation GO:0051604 233 0.039
chromatin disassembly GO:0031498 13 0.038
protein dna complex disassembly GO:0032986 12 0.038
regulation of proteolysis GO:0030162 293 0.038
nucleotide excision repair GO:0006289 31 0.036
protein processing GO:0016485 226 0.036
protein catabolic process GO:0030163 325 0.035
mitotic cell cycle GO:0000278 326 0.035
multicellular organismal aging GO:0010259 3 0.035
regulation of mitotic cell cycle GO:0007346 189 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.034
modification dependent protein catabolic process GO:0019941 209 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.034
determination of adult lifespan GO:0008340 2 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
regulation of cell cycle GO:0051726 393 0.032
regulation of cell cycle process GO:0010564 266 0.031
cellular protein catabolic process GO:0044257 261 0.031
cellular amine metabolic process GO:0044106 41 0.031
reproductive process GO:0022414 106 0.030
Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.030
amine metabolic process GO:0009308 44 0.030
negative regulation of cell cycle GO:0045786 193 0.029
regulation of mitotic cell cycle phase transition GO:1901990 118 0.028
cellular ketone metabolic process GO:0042180 80 0.027
immune response GO:0006955 307 0.027
defense response GO:0006952 315 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
female gamete generation GO:0007292 2 0.026
cellular response to histamine GO:0071420 3 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
negative regulation of proteolysis GO:0045861 132 0.026
negative regulation of protein processing GO:0010955 142 0.025
segmentation GO:0035282 4 0.025
macromolecular complex disassembly GO:0032984 60 0.025
mucosal immune response GO:0002385 21 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
mitotic sister chromatid separation GO:0051306 18 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
oogenesis GO:0048477 2 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of protein maturation GO:1903317 150 0.023
negative regulation of protein maturation GO:1903318 142 0.023
regulation of chromosome organization GO:0033044 103 0.023
chromosome segregation GO:0007059 114 0.023
mitotic cell cycle process GO:1903047 286 0.023
negative regulation of organelle organization GO:0010639 126 0.022
locomotory behavior GO:0007626 1 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
neuromuscular junction development GO:0007528 3 0.022
nucleosome disassembly GO:0006337 12 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
postreplication repair GO:0006301 12 0.021
regulation of mitotic sister chromatid separation GO:0010965 27 0.021
regeneration GO:0031099 4 0.020
regulation of protein catabolic process GO:0042176 155 0.020
cell cycle phase transition GO:0044770 173 0.020
growth GO:0040007 202 0.020
positive regulation of acrosome reaction GO:2000344 4 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
regulation of cellular protein catabolic process GO:1903362 96 0.020
negative regulation of transmission of nerve impulse GO:0051970 1 0.019
regulation of cell division GO:0051302 116 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
regulation of protein processing GO:0070613 150 0.019
protein localization to organelle GO:0033365 280 0.019
cell growth GO:0016049 160 0.019
organ formation GO:0048645 3 0.019
regulation of transmission of nerve impulse GO:0051969 2 0.019
positive regulation of organelle organization GO:0010638 195 0.019
memory GO:0007613 3 0.019
cellular component morphogenesis GO:0032989 314 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
motor neuron axon guidance GO:0008045 2 0.018
regulation of cell growth GO:0001558 135 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
innate immune response GO:0045087 178 0.018
adult locomotory behavior GO:0008344 1 0.018
regulation of growth GO:0040008 165 0.018
compound eye development GO:0048749 1 0.018
cell division GO:0051301 168 0.018
positive regulation of immune system process GO:0002684 283 0.018
negative regulation of protein modification process GO:0031400 200 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.017
sister chromatid segregation GO:0000819 54 0.017
regulation of mitosis GO:0007088 63 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of cellular component movement GO:0051270 334 0.017
cell morphogenesis GO:0000902 296 0.017
cranial nerve development GO:0021545 4 0.017
response to other organism GO:0051707 261 0.017
cellular lipid metabolic process GO:0044255 303 0.017
cellular response to light stimulus GO:0071482 34 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
developmental process involved in reproduction GO:0003006 66 0.017
Yeast
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.017
dephosphorylation GO:0016311 209 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
vesicle mediated transport GO:0016192 371 0.017
response to biotic stimulus GO:0009607 276 0.016
nerve development GO:0021675 4 0.016
response to oxygen containing compound GO:1901700 369 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.016
positive regulation of transport GO:0051050 336 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
single organism reproductive process GO:0044702 98 0.016
Yeast
regulation of chromosome segregation GO:0051983 44 0.016
positive regulation of cell growth GO:0030307 48 0.016
regulation of response to external stimulus GO:0032101 222 0.016
blastoderm segmentation GO:0007350 2 0.016
organelle fission GO:0048285 149 0.016
nuclear division GO:0000280 128 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
anterior posterior axis specification GO:0009948 2 0.016
mitotic nuclear division GO:0007067 119 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of cell death GO:0060548 345 0.015
oocyte differentiation GO:0009994 2 0.015
chemical homeostasis GO:0048878 306 0.015
defense response to bacterium GO:0042742 63 0.015
negative regulation of catabolic process GO:0009895 104 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
regulation of nuclear division GO:0051783 65 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
spermatid development GO:0007286 4 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
heart formation GO:0060914 2 0.015
positive regulation of cell death GO:0010942 263 0.015
cytoplasmic transport GO:0016482 379 0.015
associative learning GO:0008306 1 0.015
regulation of transferase activity GO:0051338 355 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
negative regulation of hydrolase activity GO:0051346 182 0.014
response to bacterium GO:0009617 144 0.014
metencephalon development GO:0022037 2 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
response to cytokine GO:0034097 232 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
regulation of secretion GO:0051046 194 0.014
startle response GO:0001964 3 0.014
apoptotic signaling pathway GO:0097190 268 0.014
cell fate determination GO:0001709 3 0.014
biological adhesion GO:0022610 331 0.014
negative regulation of chromosome organization GO:2001251 48 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
protein ubiquitination GO:0016567 314 0.014
negative regulation of protein catabolic process GO:0042177 59 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
gamma aminobutyric acid signaling pathway GO:0007214 3 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
thymus development GO:0048538 3 0.014
oocyte development GO:0048599 1 0.014
hindbrain development GO:0030902 3 0.014
single organism cellular localization GO:1902580 332 0.014
regulation of acrosome reaction GO:0060046 4 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
nucleotide catabolic process GO:0009166 408 0.013
epithelium development GO:0060429 227 0.013
positive regulation of developmental process GO:0051094 314 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
cell projection organization GO:0030030 252 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
tripartite regional subdivision GO:0007351 2 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
metal ion homeostasis GO:0055065 169 0.013
nervous system development GO:0007399 293 0.013
negative regulation of neurological system process GO:0031645 2 0.013
defense response to other organism GO:0098542 129 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
secretion by cell GO:0032940 226 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
defense response to gram positive bacterium GO:0050830 29 0.013
regulation of multi organism process GO:0043900 157 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of secretion by cell GO:1903530 177 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
regulation of sister chromatid segregation GO:0033045 27 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
maintenance of location GO:0051235 112 0.012
reproduction GO:0000003 63 0.012
Yeast
regulation of cell motility GO:2000145 299 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
response to external biotic stimulus GO:0043207 261 0.012
microtubule based process GO:0007017 210 0.012
regulation of protein localization GO:0032880 296 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
carbohydrate metabolic process GO:0005975 207 0.012
regulation of peptidase activity GO:0052547 180 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
transmembrane transport GO:0055085 399 0.012
regulation of kinase activity GO:0043549 314 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
oxidation reduction process GO:0055114 396 0.012
response to fungus GO:0009620 4 0.012
somitogenesis GO:0001756 2 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
regulation of protein transport GO:0051223 213 0.012
limbic system development GO:0021761 3 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
response to nitrogen compound GO:1901698 184 0.012
regulation of cellular response to stress GO:0080135 244 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of protein kinase activity GO:0045859 289 0.012
regulation of locomotion GO:0040012 329 0.012
spindle checkpoint GO:0031577 26 0.012
vasculature development GO:0001944 181 0.012
myoblast fusion GO:0007520 1 0.012
tissue regeneration GO:0042246 3 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
lipid metabolic process GO:0006629 381 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
antibacterial humoral response GO:0019731 24 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
mapk cascade GO:0000165 288 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of protein stability GO:0031647 87 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
visual behavior GO:0007632 2 0.011
cell adhesion GO:0007155 325 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
mitochondrion organization GO:0007005 156 0.011
cytokine production GO:0001816 247 0.011
specification of organ identity GO:0010092 3 0.011
ion homeostasis GO:0050801 230 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of cell migration GO:0030334 289 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of cell adhesion GO:0030155 166 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
organophosphate catabolic process GO:0046434 430 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
glycoprotein metabolic process GO:0009100 110 0.011
inner ear morphogenesis GO:0042472 4 0.011
embryonic camera type eye development GO:0031076 2 0.011
regulation of intracellular transport GO:0032386 195 0.011
organelle assembly GO:0070925 176 0.011
regulation of immune response GO:0050776 201 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
response to axon injury GO:0048678 1 0.011
purine containing compound catabolic process GO:0072523 411 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
single organism membrane organization GO:0044802 268 0.011
regulation of cytokine production GO:0001817 232 0.011
membrane organization GO:0061024 292 0.011
embryonic eye morphogenesis GO:0048048 2 0.011
nuclear transport GO:0051169 179 0.011
nucleoside phosphate catabolic process GO:1901292 412 0.011
salivary gland morphogenesis GO:0007435 4 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
circadian behavior GO:0048512 2 0.011
regulation of chromatin modification GO:1903308 51 0.011
positive regulation of catabolic process GO:0009896 310 0.011
intracellular protein transport GO:0006886 270 0.011
regulation of binding GO:0051098 111 0.011
purine nucleoside catabolic process GO:0006152 398 0.010
secretion GO:0046903 254 0.010
regulation of mapk cascade GO:0043408 262 0.010
peptidyl lysine modification GO:0018205 144 0.010
spinal cord development GO:0021510 4 0.010
glial cell migration GO:0008347 4 0.010
cell development GO:0048468 328 0.010
endomembrane system organization GO:0010256 196 0.010
cilium morphogenesis GO:0060271 75 0.010
cation homeostasis GO:0055080 189 0.010
cerebellum development GO:0021549 2 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
chromosome separation GO:0051304 23 0.010
angiotensin activated signaling pathway GO:0038166 4 0.010
blastocyst development GO:0001824 3 0.010
cell part morphogenesis GO:0032990 137 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
neural crest cell development GO:0014032 3 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
protein oligomerization GO:0051259 173 0.010
cellular response to ammonium ion GO:0071242 4 0.010
cellular protein complex assembly GO:0043623 188 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.010
regulation of histone modification GO:0031056 47 0.010
embryonic camera type eye morphogenesis GO:0048596 2 0.010
t cell differentiation in thymus GO:0033077 4 0.010

HIST1H4D disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.026
nervous system disease DOID:863 431 0.026
eye and adnexa disease DOID:1492 150 0.026
eye disease DOID:5614 149 0.026
central nervous system disease DOID:331 186 0.023
disease of metabolism DOID:0014667 295 0.023
retinal disease DOID:5679 118 0.018
immune system disease DOID:2914 155 0.017
inherited metabolic disorder DOID:655 242 0.017
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.016
neurodegenerative disease DOID:1289 102 0.014
hematopoietic system disease DOID:74 100 0.012
retinal degeneration DOID:8466 89 0.012
musculoskeletal system disease DOID:17 223 0.011
brain disease DOID:936 73 0.010
bone disease DOID:0080001 88 0.010
connective tissue disease DOID:65 109 0.010