Homo sapiens

31 known processes

HLA-DRA

major histocompatibility complex, class II, DR alpha

(Aliases: MLRW,FLJ51114,HLA-DRA1)

HLA-DRA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 1.000
peptide antigen assembly with mhc protein complex GO:0002501 4 1.000
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 1.000
negative regulation of antigen processing and presentation GO:0002578 5 1.000
Human
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 1.000
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 1.000
inflammatory response to antigenic stimulus GO:0002437 4 1.000
antigen processing and presentation of peptide antigen GO:0048002 18 1.000
antigen processing and presentation GO:0019882 33 1.000
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.999
mhc protein complex assembly GO:0002396 4 0.998
de novo protein folding GO:0006458 2 0.997
antigen processing and presentation of polysaccharide antigen via mhc class ii GO:0002505 2 0.997
regulation of interleukin 10 secretion GO:2001179 4 0.994
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.994
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.993
regulation of t cell proliferation GO:0042129 42 0.987
lymphocyte proliferation GO:0046651 70 0.968
t cell proliferation GO:0042098 45 0.967
positive regulation of lymphocyte proliferation GO:0050671 46 0.965
cytokine production GO:0001816 247 0.961
regulation of cytokine production GO:0001817 232 0.960
positive regulation of mononuclear cell proliferation GO:0032946 47 0.954
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.946
peptide secretion GO:0002790 51 0.945
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002581 3 0.941
Human
cellular protein complex assembly GO:0043623 188 0.941
mononuclear cell proliferation GO:0032943 71 0.937
regulation of lymphocyte proliferation GO:0050670 64 0.933
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.922
Human
cell activation GO:0001775 213 0.920
humoral immune response GO:0006959 49 0.918
protein carbohydrate complex assembly GO:0065006 2 0.915
regulation of leukocyte proliferation GO:0070663 67 0.898
positive regulation of cell activation GO:0050867 81 0.896
adaptive immune response GO:0002250 49 0.892
detection of biotic stimulus GO:0009595 21 0.892
regulation of mononuclear cell proliferation GO:0032944 65 0.887
protein tetramerization GO:0051262 47 0.882
positive regulation of lymphocyte differentiation GO:0045621 13 0.861
positive regulation of immune system process GO:0002684 283 0.846
antigen processing and presentation of exogenous antigen GO:0019884 4 0.840
t cell selection GO:0045058 4 0.833
positive regulation of lymphocyte activation GO:0051251 73 0.831
t cell activation GO:0042110 99 0.817
peptide transport GO:0015833 74 0.815
negative regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002587 2 0.813
Human
t helper 1 type immune response GO:0042088 8 0.809
regulation of cell activation GO:0050865 125 0.807
peptide hormone secretion GO:0030072 50 0.807
immune response GO:0006955 307 0.799
lymphocyte mediated immunity GO:0002449 48 0.798
regulation of leukocyte activation GO:0002694 115 0.782
interferon gamma production GO:0032609 39 0.776
regulation of t cell activation GO:0050863 77 0.776
positive regulation of leukocyte activation GO:0002696 80 0.775
cellular response to interferon gamma GO:0071346 24 0.762
negative regulation of immune system process GO:0002683 136 0.756
Human
regulation of lymphocyte activation GO:0051249 103 0.738
leukocyte activation GO:0045321 164 0.735
positive thymic t cell selection GO:0045059 1 0.734
positive regulation of immune response GO:0050778 159 0.730
lymphocyte activation GO:0046649 133 0.730
regulation of interferon gamma production GO:0032649 36 0.729
positive regulation of t cell proliferation GO:0042102 33 0.729
positive regulation of cell proliferation GO:0008284 301 0.727
nitrogen compound transport GO:0071705 191 0.712
leukocyte proliferation GO:0070661 74 0.711
cellular macromolecular complex assembly GO:0034622 324 0.711
positive regulation of leukocyte proliferation GO:0070665 48 0.705
leukocyte mediated immunity GO:0002443 59 0.701
myeloid leukocyte cytokine production GO:0061082 5 0.687
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.681
interleukin 10 production GO:0032613 17 0.678
negative regulation of defense response GO:0031348 47 0.671
positive regulation of t helper 1 type immune response GO:0002827 4 0.666
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.645
positive regulation of insulin secretion GO:0032024 10 0.641
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.634
negative regulation of cell proliferation GO:0008285 228 0.626
response to hexose GO:0009746 20 0.622
positive regulation of t cell differentiation GO:0045582 11 0.618
immune effector process GO:0002252 159 0.608
positive regulation of transport GO:0051050 336 0.605
detection of external biotic stimulus GO:0098581 19 0.587
secretion GO:0046903 254 0.579
b cell homeostasis GO:0001782 1 0.564
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.563
cellular homeostasis GO:0019725 196 0.562
cellular lipid metabolic process GO:0044255 303 0.558
positive regulation of developmental process GO:0051094 314 0.541
cellular response to ammonium ion GO:0071242 4 0.541
immunoglobulin mediated immune response GO:0016064 10 0.533
regulation of behavior GO:0050795 82 0.522
response to bacterium GO:0009617 144 0.513
negative regulation of t cell activation GO:0050868 18 0.505
regulation of defense response GO:0031347 154 0.503
positive regulation of t cell activation GO:0050870 54 0.493
type 2 immune response GO:0042092 6 0.491
innate immune response GO:0045087 178 0.490
defense response GO:0006952 315 0.475
positive regulation of hormone secretion GO:0046887 25 0.470
regulation of cytokine secretion GO:0050707 57 0.447
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.446
humoral immune response mediated by circulating immunoglobulin GO:0002455 5 0.444
cytokine secretion GO:0050663 64 0.443
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.430
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.429
hemopoiesis GO:0030097 180 0.410
b cell mediated immunity GO:0019724 10 0.409
de novo posttranslational protein folding GO:0051084 2 0.402
regulation of response to wounding GO:1903034 101 0.388
regulation of lymphocyte differentiation GO:0045619 22 0.385
negative regulation of mononuclear cell proliferation GO:0032945 15 0.385
regulation of adaptive immune response GO:0002819 33 0.380
immune system development GO:0002520 195 0.374
regulation of response to dna damage stimulus GO:2001020 94 0.371
hormone transport GO:0009914 68 0.349
hormone secretion GO:0046879 65 0.349
positive regulation of peptide secretion GO:0002793 15 0.337
chaperone mediated protein folding GO:0061077 13 0.328
inflammatory response GO:0006954 79 0.326
protein secretion GO:0009306 98 0.321
response to cytokine GO:0034097 232 0.318
regulation of response to external stimulus GO:0032101 222 0.317
negative regulation of response to external stimulus GO:0032102 83 0.316
negative regulation of cell activation GO:0050866 33 0.314
cellular chemical homeostasis GO:0055082 180 0.308
secretion by cell GO:0032940 226 0.301
cellular response to oxygen containing compound GO:1901701 276 0.290
regulation of immune response GO:0050776 201 0.281
regulation of hormone secretion GO:0046883 57 0.279
interleukin 10 secretion GO:0072608 5 0.266
mhc class ii protein complex assembly GO:0002399 4 0.266
positive regulation of secretion GO:0051047 116 0.264
regulation of peptide secretion GO:0002791 42 0.260
positive regulation of adaptive immune response GO:0002821 21 0.260
regulation of cell migration GO:0030334 289 0.257
protein carbohydrate complex subunit organization GO:0071823 2 0.250
positive regulation of cellular amine metabolic process GO:0033240 7 0.247
system process GO:0003008 349 0.238
chemokine c x c motif ligand 2 production GO:0072567 3 0.226
positive regulation of peptide hormone secretion GO:0090277 15 0.225
unsaturated fatty acid metabolic process GO:0033559 37 0.222
positive regulation of humoral immune response GO:0002922 3 0.209
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.207
negative regulation of b cell apoptotic process GO:0002903 4 0.207
cellular glucose homeostasis GO:0001678 11 0.206
regulation of leukocyte differentiation GO:1902105 61 0.204
interleukin 4 production GO:0032633 7 0.195
icosanoid metabolic process GO:0006690 35 0.189
positive regulation of leukocyte differentiation GO:1902107 37 0.184
regulation of cellular ketone metabolic process GO:0010565 50 0.180
positive t cell selection GO:0043368 2 0.176
cellular amine metabolic process GO:0044106 41 0.174
fatty acid derivative metabolic process GO:1901568 35 0.173
positive regulation of protein kinase activity GO:0045860 190 0.171
regulation of secretion GO:0051046 194 0.169
cellular response to glucose stimulus GO:0071333 10 0.165
response to oxygen containing compound GO:1901700 369 0.165
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.164
signal release GO:0023061 70 0.163
cellular response to molecule of bacterial origin GO:0071219 62 0.155
regulation of protein processing GO:0070613 150 0.151
negative regulation of lymphocyte activation GO:0051250 24 0.148
negative regulation of transport GO:0051051 176 0.145
regulation of neutrophil migration GO:1902622 10 0.144
cellular response to cytokine stimulus GO:0071345 181 0.142
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.141
protein maturation GO:0051604 233 0.130
cytokine production involved in immune response GO:0002367 27 0.128
regulation of interleukin 4 production GO:0032673 7 0.126
negative regulation of immune response GO:0050777 40 0.123
negative regulation of peptidase activity GO:0010466 91 0.123
regulation of macrophage cytokine production GO:0010935 4 0.122
glucose homeostasis GO:0042593 31 0.121
protein oligomerization GO:0051259 173 0.121
regulation of cellular response to stress GO:0080135 244 0.120
cellular response to carbohydrate stimulus GO:0071322 11 0.119
cytokine mediated signaling pathway GO:0019221 109 0.119
regulation of chemotaxis GO:0050920 74 0.116
negative regulation of multicellular organismal process GO:0051241 317 0.113
neurological system process GO:0050877 163 0.111
regulation of apoptotic signaling pathway GO:2001233 175 0.111
detection of stimulus GO:0051606 85 0.109
cellular amino acid metabolic process GO:0006520 116 0.107
response to glucose GO:0009749 19 0.103
thymic t cell selection GO:0045061 2 0.103
negative regulation of leukocyte activation GO:0002695 26 0.102
negative regulation of response to wounding GO:1903035 47 0.101
regulation of protein secretion GO:0050708 86 0.100
regulation of peptide transport GO:0090087 62 0.094
regulation of protein transport GO:0051223 213 0.094
positive regulation of cytokine production GO:0001819 167 0.090
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.086
t cell differentiation GO:0030217 29 0.086
taxis GO:0042330 157 0.086
regulation of interleukin 10 production GO:0032653 16 0.085
positive regulation of response to external stimulus GO:0032103 88 0.084
negative regulation of interferon gamma production GO:0032689 9 0.084
monocarboxylic acid biosynthetic process GO:0072330 67 0.082
regulation of protein localization GO:0032880 296 0.079
positive regulation of cell migration GO:0030335 172 0.077
negative regulation of hydrolase activity GO:0051346 182 0.077
fatty acid derivative biosynthetic process GO:1901570 18 0.076
response to external biotic stimulus GO:0043207 261 0.075
negative regulation of t cell proliferation GO:0042130 8 0.074
negative regulation of inflammatory response to antigenic stimulus GO:0002862 2 0.073
positive regulation of locomotion GO:0040017 186 0.072
negative regulation of catalytic activity GO:0043086 335 0.071
negative regulation of cell differentiation GO:0045596 171 0.069
positive regulation of cellular component movement GO:0051272 181 0.068
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.067
chemical homeostasis GO:0048878 306 0.067
regulation of peptide hormone secretion GO:0090276 41 0.066
negative regulation of homeostatic process GO:0032845 59 0.064
regulation of leukocyte chemotaxis GO:0002688 46 0.062
cell projection organization GO:0030030 252 0.059
t cell differentiation in thymus GO:0033077 4 0.058
cellular response to thyroid hormone stimulus GO:0097067 9 0.057
immunoglobulin production GO:0002377 12 0.057
cation transport GO:0006812 331 0.057
endocytosis GO:0006897 159 0.056
production of molecular mediator of immune response GO:0002440 37 0.055
response to monosaccharide GO:0034284 20 0.055
negative regulation of chemotaxis GO:0050922 13 0.053
negative regulation of blood vessel morphogenesis GO:2000181 41 0.050
cell type specific apoptotic process GO:0097285 125 0.049
detection of other organism GO:0098543 13 0.049
amine metabolic process GO:0009308 44 0.048
regulation of secretion by cell GO:1903530 177 0.048
response to interferon gamma GO:0034341 39 0.046
regulation of interleukin 12 production GO:0032655 15 0.046
positive regulation of interferon gamma production GO:0032729 26 0.045
positive regulation of behavior GO:0048520 60 0.045
negative regulation of cell death GO:0060548 345 0.044
negative regulation of cellular component organization GO:0051129 235 0.043
response to biotic stimulus GO:0009607 276 0.042
motor neuron axon guidance GO:0008045 2 0.041
positive regulation of kinase activity GO:0033674 204 0.041
carbohydrate homeostasis GO:0033500 31 0.041
post embryonic development GO:0009791 2 0.040
sprouting angiogenesis GO:0002040 29 0.040
regulation of kinase activity GO:0043549 314 0.039
unsaturated fatty acid biosynthetic process GO:0006636 21 0.038
leukocyte activation involved in immune response GO:0002366 30 0.038
positive regulation of secretion by cell GO:1903532 108 0.038
regulation of positive chemotaxis GO:0050926 14 0.037
regulation of cell development GO:0060284 161 0.036
negative regulation of programmed cell death GO:0043069 321 0.036
regulation of proteolysis GO:0030162 293 0.036
negative regulation of apoptotic process GO:0043066 316 0.035
peptidyl tyrosine phosphorylation GO:0018108 170 0.035
negative regulation of leukocyte apoptotic process GO:2000107 16 0.034
regulation of establishment of protein localization GO:0070201 242 0.034
response to fungus GO:0009620 4 0.034
azole transport GO:0045117 4 0.034
positive regulation of cell death GO:0010942 263 0.034
signal transduction in response to dna damage GO:0042770 57 0.034
regulation of complement activation lectin pathway GO:0001868 2 0.033
regulation of cell motility GO:2000145 299 0.033
cellular cation homeostasis GO:0030003 163 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
negative regulation of neuron projection development GO:0010977 15 0.031
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.031
response to corticosteroid GO:0031960 15 0.030
negative regulation of endopeptidase activity GO:0010951 84 0.030
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.030
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.029
granulocyte migration GO:0097530 40 0.028
regulation of neutrophil chemotaxis GO:0090022 10 0.028
positive regulation of cytokine production involved in immune response GO:0002720 6 0.028
lymphocyte homeostasis GO:0002260 4 0.028
cell development GO:0048468 328 0.028
negative regulation of apoptotic signaling pathway GO:2001234 97 0.028
generation of neurons GO:0048699 152 0.028
regulation of immune effector process GO:0002697 91 0.027
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.027
regulation of cell differentiation GO:0045595 393 0.027
mapk cascade GO:0000165 288 0.027
response to molecule of bacterial origin GO:0002237 82 0.026
amide transport GO:0042886 76 0.026
chemotaxis GO:0006935 157 0.026
monocarboxylic acid metabolic process GO:0032787 185 0.026
negative regulation of granulocyte chemotaxis GO:0071623 2 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
cellular response to oxidative stress GO:0034599 85 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
positive regulation of chemokine production GO:0032722 22 0.024
tissue morphogenesis GO:0048729 96 0.024
prostaglandin biosynthetic process GO:0001516 11 0.024
astrocyte chemotaxis GO:0035700 1 0.024
negative regulation of secretion GO:0051048 58 0.024
regulation of t cell differentiation GO:0045580 19 0.023
regulation of insulin secretion GO:0050796 33 0.023
regulation of homeostatic process GO:0032844 121 0.023
cellular ketone metabolic process GO:0042180 80 0.023
granulocyte chemotaxis GO:0071621 37 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.022
positive regulation of ion transport GO:0043270 87 0.022
negative regulation of leukocyte proliferation GO:0070664 16 0.022
detection of bacterium GO:0016045 13 0.022
regulation of cell projection organization GO:0031344 107 0.022
ameboidal type cell migration GO:0001667 135 0.022
cellular response to dna damage stimulus GO:0006974 379 0.021
negative regulation of inflammatory response GO:0050728 22 0.021
positive regulation of homeostatic process GO:0032846 47 0.021
regulation of b cell proliferation GO:0030888 18 0.021
cation homeostasis GO:0055080 189 0.021
protein modification by small protein removal GO:0070646 92 0.020
response to carbohydrate GO:0009743 21 0.020
insulin secretion involved in cellular response to glucose stimulus GO:0035773 7 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 7 0.020
biological adhesion GO:0022610 331 0.020
regeneration GO:0031099 4 0.020
regulation of mapk cascade GO:0043408 262 0.020
receptor metabolic process GO:0043112 81 0.020
regulation of transferase activity GO:0051338 355 0.019
negative regulation of neutrophil chemotaxis GO:0090024 2 0.019
organic acid biosynthetic process GO:0016053 97 0.019
response to organic cyclic compound GO:0014070 204 0.019
negative regulation of cell development GO:0010721 48 0.019
leukocyte chemotaxis GO:0030595 76 0.019
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
multicellular organismal aging GO:0010259 3 0.019
positive regulation of fibroblast proliferation GO:0048146 21 0.019
positive regulation of cell motility GO:2000147 177 0.019
activation of protein kinase activity GO:0032147 90 0.019
nervous system development GO:0007399 293 0.018
organelle assembly GO:0070925 176 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
regulation of peptidase activity GO:0052547 180 0.018
lymphocyte differentiation GO:0030098 35 0.018
cellular response to hexose stimulus GO:0071331 10 0.018
blood vessel morphogenesis GO:0048514 162 0.017
regulation of neurogenesis GO:0050767 82 0.017
regulation of hormone levels GO:0010817 125 0.017
regulation of inflammatory response GO:0050727 46 0.017
cognition GO:0050890 43 0.017
regulation of cytokine production involved in immune response GO:0002718 22 0.017
regulation of locomotion GO:0040012 329 0.017
cellular response to glucocorticoid stimulus GO:0071385 4 0.017
inositol lipid mediated signaling GO:0048017 55 0.017
negative regulation of lymphocyte proliferation GO:0050672 15 0.016
positive regulation of transferase activity GO:0051347 227 0.016
muscle system process GO:0003012 81 0.016
immune response inhibiting signal transduction GO:0002765 4 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
erk1 and erk2 cascade GO:0070371 104 0.016
small molecule biosynthetic process GO:0044283 157 0.015
cellular response to monosaccharide stimulus GO:0071326 10 0.015
chemokine production GO:0032602 32 0.015
negative regulation of cytokine production GO:0001818 82 0.015
fibroblast proliferation GO:0048144 33 0.015
leukocyte apoptotic process GO:0071887 31 0.015
positive regulation of neutrophil chemotaxis GO:0090023 7 0.015
insulin secretion GO:0030073 39 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
patterning of blood vessels GO:0001569 2 0.015
regulation of camp metabolic process GO:0030814 52 0.015
protein processing GO:0016485 226 0.015
positive chemotaxis GO:0050918 33 0.015
negative regulation of leukocyte differentiation GO:1902106 24 0.015
positive regulation of macrophage cytokine production GO:0060907 1 0.015
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.015
regulation of protein maturation GO:1903317 150 0.015
response to other organism GO:0051707 261 0.015
positive regulation of cell differentiation GO:0045597 211 0.014
oogenesis GO:0048477 2 0.014
regulation of intracellular transport of viral material GO:1901252 2 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
negative regulation of cell substrate adhesion GO:0010812 24 0.014
divalent metal ion transport GO:0070838 152 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
response to wounding GO:0009611 168 0.013
regulation of ion transport GO:0043269 189 0.013
regulation of neuron projection development GO:0010975 57 0.013
acute inflammatory response to antigenic stimulus GO:0002438 1 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
cellular response to dexamethasone stimulus GO:0071549 1 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.013
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.013
icosanoid biosynthetic process GO:0046456 18 0.013
maintenance of location GO:0051235 112 0.012
vesicle mediated transport GO:0016192 371 0.012
behavior GO:0007610 112 0.012
neuron development GO:0048666 113 0.012
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002580 4 0.012
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
cell cell signaling GO:0007267 155 0.012
regulation of cell substrate adhesion GO:0010810 68 0.012
regulation of protein kinase activity GO:0045859 289 0.012
cellular protein catabolic process GO:0044257 261 0.012
purine containing compound catabolic process GO:0072523 411 0.012
response to dexamethasone GO:0071548 1 0.012
cell morphogenesis GO:0000902 296 0.012
prostaglandin metabolic process GO:0006693 17 0.012
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.012
metal ion homeostasis GO:0055065 169 0.012
prostanoid biosynthetic process GO:0046457 11 0.012
regulation of signal transduction by p53 class mediator GO:1901796 26 0.011
tissue homeostasis GO:0001894 63 0.011
positive regulation of cell development GO:0010720 92 0.011
response to abiotic stimulus GO:0009628 336 0.011
positive regulation of granulocyte chemotaxis GO:0071624 9 0.011
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.011
regulation of neuron differentiation GO:0045664 70 0.011
determination of adult lifespan GO:0008340 2 0.011
wound healing GO:0042060 115 0.011
myoblast fusion GO:0007520 1 0.011
positive regulation of isotype switching GO:0045830 2 0.011
negative regulation of protein maturation GO:1903318 142 0.011
sensory organ development GO:0007423 52 0.011
regulation of acute inflammatory response to antigenic stimulus GO:0002864 1 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
regulation of cell division GO:0051302 116 0.011
lipid metabolic process GO:0006629 381 0.011
regulation of humoral immune response GO:0002920 11 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
leukocyte differentiation GO:0002521 98 0.011
multicellular organismal metabolic process GO:0044236 34 0.011
female gamete generation GO:0007292 2 0.011
positive regulation of innate immune response GO:0045089 79 0.011
regulation of anatomical structure size GO:0090066 101 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.010
intracellular protein transport GO:0006886 270 0.010
response to radiation GO:0009314 151 0.010
negative regulation of cell adhesion GO:0007162 64 0.010
cellular macromolecule catabolic process GO:0044265 380 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
cellular ion homeostasis GO:0006873 168 0.010
positive regulation of b cell activation GO:0050871 17 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.010

HLA-DRA disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.997
Human
hypersensitivity reaction disease DOID:0060056 25 0.956
Human
musculoskeletal system disease DOID:17 223 0.746
central nervous system disease DOID:331 186 0.633
nervous system disease DOID:863 431 0.633
connective tissue disease DOID:65 109 0.442
neurodegenerative disease DOID:1289 102 0.263
bone disease DOID:0080001 88 0.229
bone inflammation disease DOID:3342 10 0.108
arthritis DOID:848 8 0.108
rheumatoid arthritis DOID:7148 8 0.103
hematopoietic system disease DOID:74 100 0.012
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010