Homo sapiens

0 known processes

HMGN2

high mobility group nucleosomal binding domain 2

(Aliases: HMG17,MGC5629,MGC88718)

HMGN2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.988
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 2 0.564
v d j recombination GO:0033151 3 0.140
positive regulation of transport GO:0051050 336 0.135
response to oxygen containing compound GO:1901700 369 0.133
protein dna complex assembly GO:0065004 64 0.118
inflammatory response to antigenic stimulus GO:0002437 4 0.117
cytoplasmic transport GO:0016482 379 0.107
rna interference GO:0016246 4 0.106
response to lipid GO:0033993 206 0.100
nucleosome assembly GO:0006334 50 0.098
base excision repair GO:0006284 21 0.095
mrna metabolic process GO:0016071 175 0.094
regulation of peptidase activity GO:0052547 180 0.094
nucleosome organization GO:0034728 66 0.092
protein dna complex subunit organization GO:0071824 80 0.081
dna repair GO:0006281 198 0.080
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.073
cofactor metabolic process GO:0051186 87 0.071
regulation of proteolysis GO:0030162 293 0.071
positive regulation of cell death GO:0010942 263 0.070
apoptotic signaling pathway GO:0097190 268 0.070
regulation of intracellular transport GO:0032386 195 0.068
regulation of megakaryocyte differentiation GO:0045652 22 0.067
positive regulation of cell proliferation GO:0008284 301 0.066
defense response GO:0006952 315 0.065
dna ligation involved in dna repair GO:0051103 4 0.061
dna templated transcription initiation GO:0006352 35 0.060
response to external biotic stimulus GO:0043207 261 0.059
regulation of apoptotic signaling pathway GO:2001233 175 0.058
regulation of endopeptidase activity GO:0052548 170 0.058
response to other organism GO:0051707 261 0.055
meiotic chromosome segregation GO:0045132 4 0.054
positive regulation of apoptotic process GO:0043065 246 0.054
regulation of protein complex assembly GO:0043254 147 0.053
cellular ketone metabolic process GO:0042180 80 0.051
regulation of endothelial cell proliferation GO:0001936 56 0.050
extrinsic apoptotic signaling pathway GO:0097191 119 0.050
positive regulation of hydrolase activity GO:0051345 331 0.049
base excision repair dna ligation GO:0006288 2 0.048
regulation of secretion GO:0051046 194 0.048
negative regulation of catalytic activity GO:0043086 335 0.047
negative regulation of hydrolase activity GO:0051346 182 0.046
cellular response to dna damage stimulus GO:0006974 379 0.045
cellular response to lipid GO:0071396 127 0.045
dna packaging GO:0006323 77 0.045
nitrogen compound transport GO:0071705 191 0.044
cellular response to biotic stimulus GO:0071216 71 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.043
cellular response to oxygen containing compound GO:1901701 276 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.042
regulation of establishment of protein localization GO:0070201 242 0.042
posttranscriptional regulation of gene expression GO:0010608 213 0.042
negative regulation of apoptotic process GO:0043066 316 0.042
positive regulation of protein transport GO:0051222 135 0.042
dna replication GO:0006260 116 0.041
regulation of mitotic cell cycle GO:0007346 189 0.041
determination of adult lifespan GO:0008340 2 0.041
positive regulation of proteolysis GO:0045862 142 0.040
negative regulation of phosphatase activity GO:0010923 61 0.040
positive regulation of programmed cell death GO:0043068 249 0.040
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.040
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.039
cellular macromolecular complex assembly GO:0034622 324 0.039
ras protein signal transduction GO:0007265 73 0.038
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
negative regulation of cell death GO:0060548 345 0.037
dna conformation change GO:0071103 113 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.035
regulation of secretion by cell GO:1903530 177 0.035
inflammatory response GO:0006954 79 0.035
response to abiotic stimulus GO:0009628 336 0.035
response to organic cyclic compound GO:0014070 204 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.034
rna processing GO:0006396 255 0.034
response to hormone GO:0009725 175 0.033
negative regulation of cellular component organization GO:0051129 235 0.033
positive regulation of binding GO:0051099 45 0.033
cellular response to molecule of bacterial origin GO:0071219 62 0.033
deoxyribose phosphate metabolic process GO:0019692 6 0.033
regulation of cellular component biogenesis GO:0044087 281 0.032
cell chemotaxis GO:0060326 112 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.032
multicellular organismal aging GO:0010259 3 0.031
growth GO:0040007 202 0.031
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.030
amine metabolic process GO:0009308 44 0.030
neuromuscular junction development GO:0007528 3 0.029
regulation of hormone levels GO:0010817 125 0.029
positive regulation of endopeptidase activity GO:0010950 84 0.029
negative regulation of programmed cell death GO:0043069 321 0.028
microtubule based process GO:0007017 210 0.028
histone exchange GO:0043486 3 0.028
nuclear export GO:0051168 69 0.028
protein localization to chromosome GO:0034502 30 0.027
blastocyst development GO:0001824 3 0.027
positive regulation of immune system process GO:0002684 283 0.027
regulation of cysteine type endopeptidase activity GO:2000116 127 0.027
female gamete generation GO:0007292 2 0.027
regulation of protein transport GO:0051223 213 0.026
response to alcohol GO:0097305 64 0.026
amide transport GO:0042886 76 0.026
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
chromatin organization GO:0006325 351 0.026
response to molecule of bacterial origin GO:0002237 82 0.025
mitotic cell cycle process GO:1903047 286 0.025
chromatin assembly GO:0031497 61 0.025
negative regulation of transport GO:0051051 176 0.025
cellular amine metabolic process GO:0044106 41 0.024
regulation of nucleocytoplasmic transport GO:0046822 98 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
response to lipopolysaccharide GO:0032496 70 0.024
negative regulation of apoptotic signaling pathway GO:2001234 97 0.024
dna replication dependent nucleosome organization GO:0034723 32 0.024
protein processing GO:0016485 226 0.023
positive regulation of erythrocyte differentiation GO:0045648 11 0.023
cellular response to lipopolysaccharide GO:0071222 57 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
positive regulation of peptidase activity GO:0010952 88 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
intracellular protein transport GO:0006886 270 0.022
positive regulation of hematopoietic progenitor cell differentiation GO:1901534 5 0.022
regulation of nuclease activity GO:0032069 11 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
carbohydrate metabolic process GO:0005975 207 0.022
positive regulation of intracellular transport GO:0032388 104 0.022
negative regulation of peptidase activity GO:0010466 91 0.022
adult locomotory behavior GO:0008344 1 0.022
response to biotic stimulus GO:0009607 276 0.022
response to cytokine GO:0034097 232 0.022
atp dependent chromatin remodeling GO:0043044 25 0.022
regulation of homeostatic process GO:0032844 121 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
regulation of cellular response to stress GO:0080135 244 0.021
lipid metabolic process GO:0006629 381 0.021
regulation of protein localization GO:0032880 296 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
chemotaxis GO:0006935 157 0.021
negative regulation of developmental process GO:0051093 247 0.021
positive regulation of cell cycle process GO:0090068 106 0.021
regulation of response to dna damage stimulus GO:2001020 94 0.020
protein maturation GO:0051604 233 0.020
epithelial cell proliferation GO:0050673 128 0.020
response to estrogen GO:0043627 47 0.020
myeloid cell differentiation GO:0030099 117 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
immune response GO:0006955 307 0.020
positive regulation of secretion GO:0051047 116 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.020
regulation of binding GO:0051098 111 0.020
regulation of dephosphorylation GO:0035303 96 0.019
posttranscriptional gene silencing GO:0016441 25 0.019
response to bacterium GO:0009617 144 0.019
meiosis i GO:0007127 4 0.019
mitotic cell cycle GO:0000278 326 0.019
regulation of dna binding GO:0051101 37 0.019
methylation GO:0032259 106 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
response to steroid hormone GO:0048545 80 0.019
protein export from nucleus GO:0006611 29 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
negative regulation of organelle organization GO:0010639 126 0.018
hemopoiesis GO:0030097 180 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
secretion by cell GO:0032940 226 0.018
circulatory system development GO:0072359 262 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
microtubule organizing center organization GO:0031023 62 0.018
nervous system development GO:0007399 293 0.018
regulation of phosphatase activity GO:0010921 81 0.018
regeneration GO:0031099 4 0.018
regulation of cell cycle GO:0051726 393 0.018
protein catabolic process GO:0030163 325 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
glycosylation GO:0070085 71 0.017
mrna 3 end processing GO:0031124 24 0.017
regulation of erythrocyte differentiation GO:0045646 17 0.017
regulation of transferase activity GO:0051338 355 0.017
positive regulation of dna binding GO:0043388 17 0.017
interspecies interaction between organisms GO:0044419 156 0.017
protein localization to organelle GO:0033365 280 0.017
negative regulation of protein complex assembly GO:0031333 43 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.017
cardiovascular system development GO:0072358 262 0.016
posttranscriptional gene silencing by rna GO:0035194 25 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
reciprocal meiotic recombination GO:0007131 4 0.016
osteoblast differentiation GO:0001649 92 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
negative regulation of protein modification process GO:0031400 200 0.016
chemical homeostasis GO:0048878 306 0.016
positive regulation of epithelial cell proliferation GO:0050679 65 0.016
multi organism cellular process GO:0044764 156 0.016
protein localization to nucleus GO:0034504 136 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
activation of cysteine type endopeptidase activity GO:0097202 57 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
single organism reproductive process GO:0044702 98 0.015
protein tetramerization GO:0051262 47 0.015
viral process GO:0016032 146 0.015
secretion GO:0046903 254 0.015
cellular response to steroid hormone stimulus GO:0071383 37 0.015
neural crest cell development GO:0014032 3 0.015
regulation of kinase activity GO:0043549 314 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
response to estradiol GO:0032355 23 0.015
regulation of mrna metabolic process GO:1903311 53 0.015
regulation of cell growth GO:0001558 135 0.015
oxidation reduction process GO:0055114 396 0.015
protein glycosylation GO:0006486 62 0.014
negative regulation of dephosphorylation GO:0035305 63 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
deoxyribonucleotide metabolic process GO:0009262 6 0.014
autophagy GO:0006914 88 0.014
oogenesis GO:0048477 2 0.014
taxis GO:0042330 157 0.014
dopamine uptake involved in synaptic transmission GO:0051583 4 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
mrna catabolic process GO:0006402 56 0.014
chromatin assembly or disassembly GO:0006333 78 0.014
dna ligation GO:0006266 10 0.014
action potential GO:0001508 34 0.014
rna catabolic process GO:0006401 71 0.014
post embryonic development GO:0009791 2 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
response to drug GO:0042493 81 0.014
myeloid cell homeostasis GO:0002262 34 0.014
protein heterotetramerization GO:0051290 3 0.014
alpha amino acid metabolic process GO:1901605 72 0.014
rna splicing GO:0008380 131 0.014
cell growth GO:0016049 160 0.013
nuclear division GO:0000280 128 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
positive regulation of endothelial cell proliferation GO:0001938 37 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
positive regulation of homeostatic process GO:0032846 47 0.013
negative regulation of cell growth GO:0030308 83 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.013
purine containing compound catabolic process GO:0072523 411 0.013
negative regulation of transferase activity GO:0051348 124 0.013
regulation of cellular component movement GO:0051270 334 0.013
immune system development GO:0002520 195 0.013
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.013
positive regulation of catabolic process GO:0009896 310 0.013
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.013
negative regulation of dna templated transcription initiation GO:2000143 3 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
ribonucleoprotein complex biogenesis GO:0022613 116 0.013
chromosome segregation GO:0007059 114 0.012
single organism membrane organization GO:0044802 268 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of growth GO:0040008 165 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
response to activity GO:0014823 0 0.012
anterior posterior axis specification GO:0009948 2 0.012
regulation of myeloid cell differentiation GO:0045637 81 0.012
lipid catabolic process GO:0016042 84 0.012
organelle fission GO:0048285 149 0.012
regulation of membrane potential GO:0042391 95 0.012
regulation of hormone secretion GO:0046883 57 0.012
nucleobase containing compound transport GO:0015931 51 0.012
endothelial cell proliferation GO:0001935 65 0.012
axon cargo transport GO:0008088 2 0.012
cellular response to estradiol stimulus GO:0071392 9 0.012
negative regulation of growth GO:0045926 97 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.011
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.011
protein localization to chromatin GO:0071168 11 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
ossification GO:0001503 121 0.011
regulation of defense response GO:0031347 154 0.011
dephosphorylation GO:0016311 209 0.011
organelle localization GO:0051640 84 0.011
positive regulation of translation GO:0045727 35 0.011
neurogenesis GO:0022008 169 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
erythrocyte homeostasis GO:0034101 31 0.011
endomembrane system organization GO:0010256 196 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
spermatid development GO:0007286 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of peptide transport GO:0090087 62 0.011
biological adhesion GO:0022610 331 0.011
cell type specific apoptotic process GO:0097285 125 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of cell differentiation GO:0045595 393 0.011
vesicle mediated transport GO:0016192 371 0.011
response to growth factor GO:0070848 205 0.011
cation transport GO:0006812 331 0.011
protein deubiquitination GO:0016579 79 0.011
positive regulation of intracellular protein transport GO:0090316 76 0.011
gene silencing by rna GO:0031047 26 0.011
positive regulation of myeloid cell differentiation GO:0045639 39 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
mrna processing GO:0006397 133 0.011
anatomical structure homeostasis GO:0060249 100 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
protein oligomerization GO:0051259 173 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
positive regulation of viral process GO:0048524 37 0.011
dna replication independent nucleosome assembly GO:0006336 27 0.011
response to transforming growth factor beta GO:0071559 94 0.010
cell part morphogenesis GO:0032990 137 0.010
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.010
reproductive process GO:0022414 106 0.010
response to uv GO:0009411 73 0.010
regulation of protein processing GO:0070613 150 0.010
glycoprotein metabolic process GO:0009100 110 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.010
positive regulation of immune response GO:0050778 159 0.010
anion transport GO:0006820 161 0.010
positive regulation of cell cycle GO:0045787 140 0.010
regulation of transmembrane transport GO:0034762 139 0.010
regulation of protein catabolic process GO:0042176 155 0.010
regulation of atp metabolic process GO:1903578 29 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010

HMGN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.022
inherited metabolic disorder DOID:655 242 0.022
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
immune system disease DOID:2914 155 0.017
carbohydrate metabolic disorder DOID:2978 55 0.015
neurodegenerative disease DOID:1289 102 0.013