|
|
negative regulation of monocyte differentiation
|
GO:0045656 |
3 |
0.883
|
Human |
|
|
negative regulation of keratinocyte differentiation
|
GO:0045617 |
3 |
0.774
|
Human |
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.635
|
Human |
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.531
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.518
|
Human Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.472
|
Mouse |
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.472
|
Human |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.447
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.435
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.410
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.347
|
Human |
|
|
negative regulation of leukocyte migration
|
GO:0002686 |
14 |
0.320
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.303
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.286
|
Human |
|
|
negative regulation of epidermis development
|
GO:0045683 |
5 |
0.264
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.261
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.255
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.252
|
Human Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.247
|
Human |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.236
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.221
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.219
|
Human Fly |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.216
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.212
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.205
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.199
|
Human |
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.193
|
Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.193
|
Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.182
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.180
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.177
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.175
|
Human Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.173
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.166
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.165
|
Human |
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.163
|
Mouse |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.157
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.155
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.150
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.150
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.147
|
Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.147
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.143
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.137
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.136
|
Human |
|
|
organ formation
|
GO:0048645 |
3 |
0.133
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.131
|
Human |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.129
|
Human |
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.129
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.126
|
Human |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.125
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.124
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.123
|
Human Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.122
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.119
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.117
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.117
|
Human Fly |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.114
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.114
|
Human Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.112
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.110
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.109
|
Human |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.108
|
Human |
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.107
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.106
|
Human |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.104
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.103
|
Mouse |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.103
|
Mouse |
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.101
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.100
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.097
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.096
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.094
|
Human |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.094
|
Human |
|
|
regionalization
|
GO:0003002 |
29 |
0.093
|
Mouse Fly |
|
|
monocyte differentiation
|
GO:0030224 |
15 |
0.093
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.092
|
Human |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.092
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.086
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.085
|
Human |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.085
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.085
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.084
|
Human |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.084
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.082
|
Human Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.082
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.081
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.080
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.080
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.080
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.078
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.078
|
Mouse |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.076
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.075
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.074
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.074
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.073
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.072
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.071
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.071
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.070
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.070
|
Fly |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.069
|
Human |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.067
|
Human |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.066
|
Human |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.064
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.063
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.063
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.061
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.061
|
Human |
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.059
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.058
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.057
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.057
|
|
|
|
abducens nerve morphogenesis
|
GO:0021598 |
1 |
0.057
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.057
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.056
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.055
|
Mouse Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.055
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.055
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.054
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.053
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.053
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.053
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.052
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.051
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.051
|
Mouse Fly |
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.051
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.051
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.050
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.050
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.050
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.050
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.050
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.049
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.048
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.048
|
|
|
|
lung associated mesenchyme development
|
GO:0060484 |
1 |
0.047
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.046
|
|
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.046
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.046
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.046
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.045
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.045
|
Human |
|
|
regulation of monocyte differentiation
|
GO:0045655 |
5 |
0.045
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.045
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.044
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.044
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.044
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.044
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.044
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.044
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.044
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.044
|
Human |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.043
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.043
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.043
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.043
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.043
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.042
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.042
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.042
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.042
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.041
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.041
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.041
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.040
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.040
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.040
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.040
|
Human |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.040
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.039
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.039
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.039
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.039
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.039
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.038
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.038
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.037
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.037
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.037
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.037
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.037
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.036
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.036
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.036
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.035
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.035
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.035
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.035
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.035
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.035
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.035
|
|
|
|
growth
|
GO:0040007 |
202 |
0.035
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.034
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.034
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.034
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.034
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.034
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
Fly |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.034
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.034
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.033
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.033
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.033
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.033
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.033
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.033
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.032
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.032
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.032
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.032
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.031
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.031
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.031
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.031
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.031
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.031
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.031
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.031
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.030
|
|
|
|
memory
|
GO:0007613 |
3 |
0.030
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.030
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.030
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.030
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.030
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.030
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.030
|
|
|
|
head development
|
GO:0060322 |
108 |
0.030
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.030
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
8 |
0.030
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.030
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.029
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.029
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.029
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.029
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.029
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.028
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.028
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.028
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.028
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.028
|
Fly |
|
|
histone modification
|
GO:0016570 |
251 |
0.028
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.027
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.027
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.027
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.027
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.027
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.027
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.027
|
|
|
|
mating
|
GO:0007618 |
1 |
0.027
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.027
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.027
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.027
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.026
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.026
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.026
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.026
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.026
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.026
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.026
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.026
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.026
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.026
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.025
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.025
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.025
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.025
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.025
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.025
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.025
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.025
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.025
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.025
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.025
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.025
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.024
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.024
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.024
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.024
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.024
|
Fly |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.024
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.024
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.024
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.024
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.024
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.024
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.024
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.024
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.024
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.024
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.024
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.023
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.023
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.023
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.023
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.023
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.023
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.023
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.023
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.023
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.022
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.022
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.022
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.022
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.022
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.022
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.022
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.022
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.022
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.022
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.022
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.022
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.022
|
|
|
|
semicircular canal morphogenesis
|
GO:0048752 |
1 |
0.022
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.022
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.022
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.022
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.022
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.021
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.021
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.021
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.021
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.021
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.021
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.021
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.021
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.021
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.021
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.021
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.021
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.021
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.020
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.020
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.020
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.020
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.020
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.020
|
Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.020
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.020
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.020
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.020
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.020
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.020
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.020
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.020
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.020
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.020
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.020
|
|
|
|
embryonic neurocranium morphogenesis
|
GO:0048702 |
1 |
0.020
|
|
|
|
mesonephric duct development
|
GO:0072177 |
3 |
0.020
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.020
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.019
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.019
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.019
|
|
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.019
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.019
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.019
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.019
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.019
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.019
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.019
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.019
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.019
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.019
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.019
|
|
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.019
|
Human |
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.019
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.019
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.019
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.019
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.019
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.019
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.019
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.019
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.019
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.019
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.019
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.019
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.018
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.018
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.018
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.018
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.018
|
|
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.018
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.018
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.018
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.018
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.018
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.018
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.018
|
|
|
|
regulation of thyroid hormone generation
|
GO:2000609 |
2 |
0.018
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.018
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.018
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.018
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.018
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.018
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.018
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.017
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.017
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.017
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.017
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.017
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.017
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.017
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.017
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.017
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.017
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.017
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.017
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.017
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.017
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.017
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.017
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.017
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.017
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.017
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.017
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.017
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.017
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.017
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.017
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.017
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.017
|
|
|
|
outer ear morphogenesis
|
GO:0042473 |
2 |
0.017
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.016
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.016
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.016
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.016
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.016
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.016
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.016
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.016
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.016
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.016
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.016
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.016
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.016
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.016
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.016
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.016
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.016
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.016
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.016
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.016
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.016
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.016
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.016
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.016
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.016
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.016
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.016
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.016
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.016
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.016
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.016
|
|
