|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.991
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.985
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.980
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.979
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.976
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.965
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.943
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.926
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.907
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.871
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.870
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.844
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.842
|
Yeast |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.840
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.838
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.835
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.822
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.809
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.796
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.749
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.712
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.699
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.667
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.666
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.659
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.650
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.645
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.604
|
Yeast |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.597
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.571
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.566
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.548
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.545
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.538
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.530
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.528
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.502
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.502
|
Human Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.493
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.476
|
Human Worm |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.473
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.473
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.470
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.463
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.444
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.433
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.412
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.402
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.391
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.389
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.381
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.380
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.379
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.358
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.316
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.313
|
Yeast Worm Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.311
|
Mouse |
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.304
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.296
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.291
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.288
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.253
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.249
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.245
|
Human Worm Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.242
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.239
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.230
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.227
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.226
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.225
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.222
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.221
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.219
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.215
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.213
|
Human Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.213
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.201
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.200
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.196
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.196
|
Worm Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.187
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.185
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.180
|
Worm Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.174
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.173
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.173
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.166
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.162
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.160
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.156
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.156
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.150
|
Fly |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.149
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.148
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.140
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.139
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.139
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.138
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.136
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.135
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.134
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.133
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.131
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.125
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.123
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.114
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.114
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.110
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.110
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.104
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.104
|
Human |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.103
|
Yeast |
|
|
coenzyme catabolic process
|
GO:0009109 |
5 |
0.102
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.100
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.093
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.092
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.088
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.086
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.086
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.086
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.086
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.085
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.084
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.083
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.081
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.080
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.078
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.077
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.077
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.077
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.077
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.076
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.076
|
|
|
|
system process
|
GO:0003008 |
349 |
0.075
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.074
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.073
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.072
|
Mouse |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.070
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.068
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.067
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.066
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.065
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.065
|
Yeast Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.065
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.065
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.065
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.064
|
Worm Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.063
|
Fly |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.063
|
Yeast |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.061
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.061
|
|
|
|
head development
|
GO:0060322 |
108 |
0.060
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.060
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.059
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.058
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.057
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.057
|
Yeast |
|
|
exocytosis
|
GO:0006887 |
71 |
0.056
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.055
|
Worm Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.055
|
Mouse Worm |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.055
|
Human Fly |
|
|
developmental growth
|
GO:0048589 |
48 |
0.055
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.055
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.054
|
Human Mouse Worm |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.054
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.052
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.052
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.052
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.052
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.051
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.050
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.050
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.049
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.048
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.048
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.048
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.047
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.047
|
Yeast |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.045
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.045
|
Mouse Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.044
|
Human |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.044
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.044
|
Yeast Fly |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.043
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.043
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.042
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.041
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.041
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.041
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.041
|
Yeast Worm Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.041
|
Human Yeast Fly |
|
|
visual behavior
|
GO:0007632 |
2 |
0.040
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.040
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.040
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.039
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.039
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.039
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.039
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.038
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.038
|
Yeast |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.038
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.037
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.037
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.036
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.036
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.036
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.036
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.035
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.034
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.033
|
Yeast |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.033
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.033
|
Yeast |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.032
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.032
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.031
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.031
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.031
|
Yeast Worm Fly |
|
|
reproduction
|
GO:0000003 |
63 |
0.031
|
Yeast Worm Fly |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.030
|
|
|
|
learning
|
GO:0007612 |
11 |
0.030
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.029
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.029
|
Yeast |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.029
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.029
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.029
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.029
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.028
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.028
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.028
|
Yeast |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.028
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.028
|
|
|
|
memory
|
GO:0007613 |
3 |
0.028
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.027
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.027
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.027
|
Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.027
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.027
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.027
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.027
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.026
|
Human Fly |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.026
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.026
|
Fly |
|
|
neuron death
|
GO:0070997 |
65 |
0.026
|
Human Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.025
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.025
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.025
|
Yeast |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.025
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.025
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.025
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.025
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.025
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.024
|
Fly |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.024
|
Yeast |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.024
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.024
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.024
|
Yeast Worm Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.024
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.024
|
Fly |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.024
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.024
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.023
|
|
|
|
ral protein signal transduction
|
GO:0032484 |
1 |
0.023
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.023
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.023
|
Yeast Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.023
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.023
|
Yeast Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.023
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.023
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.023
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.023
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.023
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.023
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.023
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.022
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.022
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.022
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.022
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.021
|
Fly |
|
|
positive regulation of ral gtpase activity
|
GO:0032852 |
1 |
0.021
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.021
|
Worm |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.021
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.021
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.020
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.020
|
Mouse |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.020
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.020
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.020
|
Human Mouse |
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.019
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.019
|
Fly |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.019
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.019
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.019
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.019
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.019
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.019
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.019
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.018
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.018
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.018
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.018
|
Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.018
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.018
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.018
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.018
|
|
|
|
regulation of ral protein signal transduction
|
GO:0032485 |
1 |
0.018
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.017
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.017
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.017
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.017
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.017
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.016
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.016
|
Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.016
|
Yeast Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.016
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.016
|
Yeast |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.016
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.016
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.016
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.016
|
Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.015
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.015
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.015
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.015
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.015
|
Fly |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.015
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.015
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.015
|
Yeast |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.015
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.015
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.015
|
Yeast Worm Fly |
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.015
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.014
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.014
|
Worm |
|
|
regulation of ral gtpase activity
|
GO:0032315 |
1 |
0.014
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.014
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.014
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.014
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.014
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.014
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.014
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.014
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.014
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.014
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.014
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.013
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.013
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.013
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.013
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.013
|
Fly |
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.013
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.013
|
Worm Fly |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.013
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.013
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.013
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.013
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.013
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.013
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.013
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.013
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.013
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.013
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.013
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.013
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.012
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.012
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.012
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.012
|
Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.012
|
Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.012
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.012
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.012
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.012
|
Worm |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.012
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.012
|
Worm |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.012
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.012
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.012
|
Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.012
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.012
|
Mouse Fly |
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.012
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.012
|
Mouse Fly |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.012
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.012
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.012
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.011
|
Yeast |
|
|
cell activation
|
GO:0001775 |
213 |
0.011
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.011
|
Worm |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.011
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.011
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.011
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.011
|
Fly |
|
|
platelet activation
|
GO:0030168 |
44 |
0.011
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
6 |
0.011
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.011
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.011
|
|
|
|
long chain fatty acid metabolic process
|
GO:0001676 |
30 |
0.011
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.011
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.011
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.011
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.011
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.011
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.011
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.011
|
Human |
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.011
|
Yeast |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.011
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.011
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.011
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.011
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.010
|
Human |
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.010
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.010
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.010
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.010
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.010
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.010
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.010
|
|
|
|
regulation of rap gtpase activity
|
GO:0032317 |
8 |
0.010
|
Worm |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.010
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.010
|
|
