|
|
protein folding
|
GO:0006457 |
38 |
1.000
|
Yeast |
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
1.000
|
Fly |
|
|
protein refolding
|
GO:0042026 |
14 |
1.000
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
1.000
|
Fly |
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
1.000
|
Fly |
|
|
de novo protein folding
|
GO:0006458 |
2 |
1.000
|
|
|
|
chaperone mediated protein folding
|
GO:0061077 |
13 |
1.000
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
1.000
|
Yeast Fly |
|
|
de novo posttranslational protein folding
|
GO:0051084 |
2 |
1.000
|
|
|
|
chaperone cofactor dependent protein refolding
|
GO:0070389 |
4 |
1.000
|
|
|
|
chaperone mediated protein folding requiring cofactor
|
GO:0051085 |
1 |
1.000
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.998
|
Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.995
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.992
|
|
|
|
translation
|
GO:0006412 |
132 |
0.991
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.991
|
|
|
|
regulation of transposition
|
GO:0010528 |
7 |
0.988
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.974
|
Fly |
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.973
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.973
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.971
|
Human Yeast |
|
|
protein transmembrane transport
|
GO:0071806 |
25 |
0.967
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.965
|
Worm Fly |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.965
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.957
|
Human |
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
3 |
0.945
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.944
|
Worm |
|
|
peptidyl proline modification
|
GO:0018208 |
15 |
0.933
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.933
|
Human |
|
|
srp dependent cotranslational protein targeting to membrane
|
GO:0006614 |
2 |
0.932
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.929
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.924
|
Human |
|
|
small nucleolar ribonucleoprotein complex assembly
|
GO:0000491 |
3 |
0.921
|
Yeast |
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.914
|
Fly |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.908
|
Human Yeast Worm |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.883
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.878
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.865
|
|
|
|
protein import into mitochondrial outer membrane
|
GO:0045040 |
4 |
0.856
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.851
|
|
|
|
outer mitochondrial membrane organization
|
GO:0007008 |
4 |
0.849
|
Human |
|
|
toxin transport
|
GO:1901998 |
4 |
0.847
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.839
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.836
|
Human Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.825
|
Fly |
|
|
sleep
|
GO:0030431 |
2 |
0.815
|
Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.813
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.810
|
Human Yeast Worm |
|
|
cotranslational protein targeting to membrane
|
GO:0006613 |
2 |
0.808
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.808
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.802
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.798
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.795
|
Yeast |
|
|
regulation of atp metabolic process
|
GO:1903578 |
29 |
0.783
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.783
|
Fly |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.779
|
Human Yeast Worm |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.778
|
Human Yeast Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.771
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.764
|
Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.761
|
Worm |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.761
|
Fly |
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.758
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.755
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.752
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.751
|
Worm Fly |
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.748
|
Human |
|
|
cellular heat acclimation
|
GO:0070370 |
3 |
0.741
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.731
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.727
|
Zebrafish |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.723
|
Fly |
|
|
aging
|
GO:0007568 |
66 |
0.715
|
Worm |
|
|
box c d snornp assembly
|
GO:0000492 |
3 |
0.712
|
Yeast |
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.709
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.708
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.696
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.693
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.680
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.680
|
|
|
|
protein peptidyl prolyl isomerization
|
GO:0000413 |
8 |
0.669
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.663
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.660
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.632
|
|
|
|
growth
|
GO:0040007 |
202 |
0.623
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.623
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.619
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.616
|
Human Yeast Worm |
|
|
skeletal muscle myosin thick filament assembly
|
GO:0030241 |
2 |
0.607
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.604
|
Human Yeast Worm |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.601
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.598
|
Fly |
|
|
proteasome assembly
|
GO:0043248 |
7 |
0.591
|
Yeast |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.555
|
Human Yeast Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.546
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.539
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.536
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.532
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.517
|
Human Yeast Worm |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.516
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.513
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.510
|
Human Yeast Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.509
|
Worm |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.508
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.508
|
Worm Fly |
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.495
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.495
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.492
|
Human Yeast Worm |
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.491
|
Yeast Fly |
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.487
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.484
|
Human Yeast Worm |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.483
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.478
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.476
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.472
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.467
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.457
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.454
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.453
|
|
|
|
protein targeting to mitochondrion
|
GO:0006626 |
19 |
0.443
|
Human |
|
|
protein processing
|
GO:0016485 |
226 |
0.434
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.429
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.429
|
Human Yeast Worm |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.419
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.417
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.414
|
Human Yeast Worm |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.413
|
Zebrafish |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.413
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.409
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.404
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.401
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.395
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.394
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.383
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.377
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.377
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.375
|
Human Yeast Worm |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.363
|
Human Yeast Worm |
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.351
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.351
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.350
|
Human Yeast Worm |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.349
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.345
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.336
|
Worm Fly |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.332
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.329
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.323
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.310
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.307
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.305
|
Fly |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.304
|
Fly |
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.299
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.297
|
Human Yeast Worm |
|
|
oocyte development
|
GO:0048599 |
1 |
0.292
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.278
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.278
|
|
|
|
system process
|
GO:0003008 |
349 |
0.276
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.269
|
Fly |
|
|
response to heat
|
GO:0009408 |
21 |
0.266
|
Yeast Fly |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.266
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.257
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.239
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.238
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.236
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.230
|
Worm |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.228
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.227
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.222
|
Human |
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.220
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.219
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.210
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.209
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.207
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.206
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.204
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.203
|
Human Yeast Worm |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.203
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.202
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.201
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.201
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.201
|
|
|
|
fibril organization
|
GO:0097435 |
10 |
0.199
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.198
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.197
|
|
|
|
chaperone mediated protein complex assembly
|
GO:0051131 |
9 |
0.197
|
Human |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.197
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.193
|
Human Yeast Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.191
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
3 |
0.188
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.185
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.183
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.183
|
|
|
|
negative regulation of fibril organization
|
GO:1902904 |
1 |
0.182
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.174
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.172
|
Human Yeast Worm |
|
|
renal system development
|
GO:0072001 |
63 |
0.169
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.169
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.168
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.166
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.163
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.162
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.152
|
Human Yeast Worm |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.151
|
|
|
|
establishment of protein localization to endoplasmic reticulum
|
GO:0072599 |
11 |
0.150
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.150
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.148
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.144
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.144
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.143
|
Human Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.141
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
19 |
0.141
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.141
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.140
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.139
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.137
|
Human Yeast Worm |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.135
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.134
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.132
|
Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.131
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.131
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.131
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.127
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.126
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.126
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.124
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.122
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.118
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.115
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.112
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.111
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.111
|
Human Yeast Worm |
|
|
nervous system development
|
GO:0007399 |
293 |
0.110
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.109
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.108
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.108
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.108
|
Human Yeast Worm |
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.106
|
Yeast |
|
|
vasculature development
|
GO:0001944 |
181 |
0.105
|
Zebrafish |
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.105
|
Yeast |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.105
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.103
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.102
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.102
|
Worm |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.102
|
Human Yeast Worm |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.101
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.101
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.101
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.100
|
Yeast |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.100
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.098
|
|
|
|
copper ion transport
|
GO:0006825 |
3 |
0.097
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.097
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.096
|
|
|
|
regulation of atp catabolic process
|
GO:1903289 |
25 |
0.094
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.093
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.093
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.092
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.092
|
Human Yeast Worm |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.092
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.092
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.091
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
22 |
0.091
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.090
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.088
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.087
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.087
|
Human |
|
|
cell maturation
|
GO:0048469 |
11 |
0.087
|
Fly |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.084
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.083
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.083
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.082
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.080
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.080
|
Worm Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.080
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.078
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.078
|
Fly |
|
|
genitalia development
|
GO:0048806 |
10 |
0.077
|
Worm |
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
18 |
0.076
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.076
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.076
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.075
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.075
|
Human Yeast Worm |
|
|
response to uv a
|
GO:0070141 |
6 |
0.075
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.074
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.073
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.072
|
Human Yeast Worm |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.071
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.071
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.071
|
|
|
|
detection of external stimulus
|
GO:0009581 |
15 |
0.071
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.069
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.069
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.068
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.068
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.068
|
Human Yeast Worm |
|
|
cell growth
|
GO:0016049 |
160 |
0.068
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.068
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.066
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.066
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.064
|
|
|
|
translational initiation
|
GO:0006413 |
48 |
0.062
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.062
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.062
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.061
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.060
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.059
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.059
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.058
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.057
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.057
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.056
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.056
|
Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.056
|
Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.056
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.056
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.056
|
|
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
6 |
0.056
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.055
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.054
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.054
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.054
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.054
|
Fly |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.054
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
43 |
0.053
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.053
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.053
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.053
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.051
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.050
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.050
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.049
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.049
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.049
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.049
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.048
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.048
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.047
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.046
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.046
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.045
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.045
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.045
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.044
|
Human |
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.044
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.044
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.044
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.043
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
12 |
0.043
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.043
|
|
|
|
detection of light stimulus involved in visual perception
|
GO:0050908 |
9 |
0.043
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.042
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.041
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.041
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.041
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.040
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.040
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.040
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.040
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.040
|
Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.039
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.039
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.039
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.039
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.039
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.038
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.038
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.038
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.038
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.038
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.038
|
|
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.038
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.038
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.037
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.037
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.037
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.036
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.036
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.035
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.035
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.035
|
Fly |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.035
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.034
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.034
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.034
|
Human |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.034
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.034
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.034
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.033
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.033
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.032
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.031
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.031
|
|
|
|
myofibril assembly
|
GO:0030239 |
10 |
0.031
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.031
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.031
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.031
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.031
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.030
|
Fly |
|
|
protein secretion
|
GO:0009306 |
98 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.029
|
|
|
|
positive regulation of response to tumor cell
|
GO:0002836 |
8 |
0.029
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.029
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.029
|
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.029
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.028
|
|
|
|
cellular amino acid catabolic process
|
GO:0009063 |
31 |
0.028
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.028
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.028
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.028
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.028
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.028
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.027
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.027
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.027
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.027
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.026
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.026
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.026
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.026
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.025
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.025
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.025
|
|
|
|
response to oxygen radical
|
GO:0000305 |
6 |
0.025
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.025
|
|
|
|
positive regulation of atp catabolic process
|
GO:1903291 |
19 |
0.025
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.025
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.025
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.025
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.024
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.024
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.024
|
Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.024
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
37 |
0.024
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.024
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.024
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.024
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.024
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.023
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.023
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.023
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.023
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.023
|
Fly |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.023
|
Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.023
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.023
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.022
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.022
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.022
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.022
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.022
|
Fly |
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.022
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.021
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.021
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.021
|
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
3 |
0.021
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.020
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.020
|
Fly |
|
|
germ cell development
|
GO:0007281 |
8 |
0.020
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.019
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.019
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.019
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.019
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.019
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.019
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.019
|
Yeast |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.019
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.019
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.018
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.018
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.017
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.017
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.017
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.017
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.017
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.017
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.017
|
|
|
|
body morphogenesis
|
GO:0010171 |
11 |
0.017
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.017
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.016
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.016
|
|
|
|
glomerular mesangial cell development
|
GO:0072144 |
1 |
0.016
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.016
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.016
|
|
|
|
positive regulation of atp metabolic process
|
GO:1903580 |
20 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.015
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.015
|
|
