Homo sapiens

221 known processes

HSPA1A

heat shock 70kDa protein 1A

(Aliases: HSPA1,HSP72,FLJ54392,FLJ54370,HSP70-1A,FLJ54408,HSPA1B,FLJ54303,HSP70I,FLJ75127,HSP70-1)

HSPA1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.999
protein refolding GO:0042026 14 0.994
intracellular protein transmembrane transport GO:0065002 24 0.981
Yeast
positive regulation of erythrocyte differentiation GO:0045648 11 0.968
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.953
ribonucleoside monophosphate catabolic process GO:0009158 158 0.951
protein localization to endoplasmic reticulum GO:0070972 19 0.943
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 158 0.936
srp dependent cotranslational protein targeting to membrane GO:0006614 2 0.931
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.918
response to unfolded protein GO:0006986 24 0.918
heat acclimation GO:0010286 3 0.907
inclusion body assembly GO:0070841 17 0.890
nucleoside monophosphate catabolic process GO:0009125 159 0.869
atp catabolic process GO:0006200 157 0.860
cellular response to topologically incorrect protein GO:0035967 19 0.844
Fly
ribonucleoprotein complex disassembly GO:0032988 7 0.838
Yeast
response to topologically incorrect protein GO:0035966 29 0.796
glycosyl compound catabolic process GO:1901658 413 0.795
regulation of erythrocyte differentiation GO:0045646 17 0.790
regulation of meiotic cell cycle GO:0051445 4 0.781
Worm
regulation of myeloid cell differentiation GO:0045637 81 0.778
retrograde transport endosome to golgi GO:0042147 45 0.776
Worm
cellular macromolecule catabolic process GO:0044265 380 0.770
protein localization to mitochondrion GO:0070585 25 0.769
Yeast
nucleoside triphosphate catabolic process GO:0009143 394 0.754
ribonucleoside catabolic process GO:0042454 406 0.738
nucleoside monophosphate metabolic process GO:0009123 191 0.728
positive regulation of meiotic cell cycle GO:0051446 2 0.722
Worm
purine nucleoside monophosphate metabolic process GO:0009126 186 0.706
ribonucleoside monophosphate metabolic process GO:0009161 187 0.706
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.706
ribonucleotide catabolic process GO:0009261 405 0.702
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.699
signal transduction in absence of ligand GO:0038034 22 0.695
purine nucleoside triphosphate catabolic process GO:0009146 392 0.692
posttranscriptional gene silencing by rna GO:0035194 25 0.690
Fly
negative regulation of fibril organization GO:1902904 1 0.679
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.676
protein ubiquitination GO:0016567 314 0.668
organophosphate catabolic process GO:0046434 430 0.665
purine ribonucleotide catabolic process GO:0009154 404 0.664
mrna catabolic process GO:0006402 56 0.657
nucleoside phosphate catabolic process GO:1901292 412 0.650
protein modification by small protein conjugation GO:0032446 342 0.649
nucleotide catabolic process GO:0009166 408 0.649
negative regulation of inclusion body assembly GO:0090084 9 0.647
protein folding GO:0006457 38 0.635
cotranslational protein targeting to membrane GO:0006613 2 0.633
Yeast
nucleoside catabolic process GO:0009164 408 0.632
regulation of inclusion body assembly GO:0090083 13 0.631
regulation of protein ubiquitination GO:0031396 95 0.630
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.622
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.599
Yeast
purine ribonucleoside catabolic process GO:0046130 398 0.595
purine nucleotide catabolic process GO:0006195 405 0.579
establishment of protein localization to mitochondrion GO:0072655 22 0.576
Yeast
rna interference GO:0016246 4 0.555
Fly
positive regulation of myeloid cell differentiation GO:0045639 39 0.548
cellular protein catabolic process GO:0044257 261 0.546
Yeast
purine nucleoside catabolic process GO:0006152 398 0.545
atp metabolic process GO:0046034 176 0.544
purine nucleoside triphosphate metabolic process GO:0009144 412 0.529
regulation of apoptotic signaling pathway GO:2001233 175 0.519
protein import GO:0017038 130 0.519
Yeast
establishment of protein localization to membrane GO:0090150 121 0.516
Yeast
mrna metabolic process GO:0016071 175 0.515
purine containing compound catabolic process GO:0072523 411 0.506
negative regulation of apoptotic signaling pathway GO:2001234 97 0.503
single organism membrane organization GO:0044802 268 0.499
Yeast
protein catabolic process GO:0030163 325 0.499
Yeast
cellular response to heat GO:0034605 14 0.498
mitochondrial transport GO:0006839 60 0.494
Yeast
membrane organization GO:0061024 292 0.493
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 412 0.486
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.466
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.456
chaperone cofactor dependent protein refolding GO:0070389 4 0.455
protein import into nucleus GO:0006606 104 0.454
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.446
protein localization to membrane GO:0072657 160 0.437
Yeast
mitochondrion organization GO:0007005 156 0.430
Yeast
establishment of protein localization to organelle GO:0072594 172 0.414
Yeast
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.406
determination of adult lifespan GO:0008340 2 0.401
Worm
establishment of protein localization to endoplasmic reticulum GO:0072599 11 0.396
Yeast
negative regulation of cell death GO:0060548 345 0.395
secretion by cell GO:0032940 226 0.389
Fly
protein localization to organelle GO:0033365 280 0.384
Yeast
fibril organization GO:0097435 10 0.384
Human
hemopoiesis GO:0030097 180 0.382
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.373
macromolecular complex disassembly GO:0032984 60 0.373
Yeast
positive regulation of immune system process GO:0002684 283 0.366
posttranscriptional gene silencing GO:0016441 25 0.358
Fly
regulation of cell differentiation GO:0045595 393 0.357
negative regulation of apoptotic process GO:0043066 316 0.356
nucleoside triphosphate metabolic process GO:0009141 422 0.352
organelle disassembly GO:1903008 9 0.352
Yeast
neurotransmitter secretion GO:0007269 4 0.350
Fly
negative regulation of cell growth GO:0030308 83 0.327
erythrocyte differentiation GO:0030218 28 0.322
apoptotic signaling pathway GO:0097190 268 0.319
cellular protein complex disassembly GO:0043624 36 0.316
Yeast
response to abiotic stimulus GO:0009628 336 0.314
protein depolymerization GO:0051261 30 0.301
Yeast
negative regulation of protein modification process GO:0031400 200 0.295
protein targeting GO:0006605 187 0.295
Yeast
secretion GO:0046903 254 0.294
Fly
cellular heat acclimation GO:0070370 3 0.293
response to cytokine GO:0034097 232 0.280
single organism cellular localization GO:1902580 332 0.277
Yeast
positive regulation of cell cycle GO:0045787 140 0.274
Worm
positive regulation of developmental process GO:0051094 314 0.270
negative regulation of protein metabolic process GO:0051248 391 0.260
ubiquitin dependent protein catabolic process GO:0006511 206 0.259
ribonucleoside triphosphate catabolic process GO:0009203 391 0.258
signal release GO:0023061 70 0.256
Fly
negative regulation of programmed cell death GO:0043069 321 0.256
regulation of homeostatic process GO:0032844 121 0.256
gene silencing by rna GO:0031047 26 0.255
Fly
mitotic cell cycle GO:0000278 326 0.249
Worm
positive regulation of cell differentiation GO:0045597 211 0.248
taxis GO:0042330 157 0.228
Fly
nucleocytoplasmic transport GO:0006913 176 0.226
Yeast
response to temperature stimulus GO:0009266 22 0.225
single organism nuclear import GO:1902593 104 0.223
Yeast
cell growth GO:0016049 160 0.222
regulation of gene expression epigenetic GO:0040029 73 0.214
Fly
intracellular protein transport GO:0006886 270 0.214
Yeast
regulation of growth GO:0040008 165 0.209
negative regulation of protein ubiquitination GO:0031397 35 0.200
positive regulation of nucleoside metabolic process GO:0045979 186 0.199
modification dependent protein catabolic process GO:0019941 209 0.198
regulation of cell cycle GO:0051726 393 0.194
Worm
de novo protein folding GO:0006458 2 0.193
posttranscriptional regulation of gene expression GO:0010608 213 0.191
Fly
vesicle mediated transport GO:0016192 371 0.189
Yeast Worm Fly
spinal cord development GO:0021510 4 0.187
negative regulation of cell proliferation GO:0008285 228 0.183
negative regulation of cellular component organization GO:0051129 235 0.182
nuclear transport GO:0051169 179 0.182
Yeast
response to heat GO:0009408 21 0.178
positive regulation of homeostatic process GO:0032846 47 0.173
cellular response to misfolded protein GO:0071218 2 0.173
positive regulation of catabolic process GO:0009896 310 0.170
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.156
protein localization to nucleus GO:0034504 136 0.155
Yeast
neuron differentiation GO:0030182 138 0.148
Fly
cell projection organization GO:0030030 252 0.141
Fly
nuclear import GO:0051170 106 0.139
Yeast
protein import into nucleus translocation GO:0000060 22 0.138
Yeast
cellular component disassembly GO:0022411 92 0.136
Yeast
positive regulation of cellular catabolic process GO:0031331 284 0.131
cell morphogenesis GO:0000902 296 0.129
Fly
protein transmembrane transport GO:0071806 25 0.127
Yeast
nervous system development GO:0007399 293 0.126
Fly
cell development GO:0048468 328 0.125
Fly
striated muscle cell apoptotic process GO:0010658 3 0.123
regulation of protein kinase activity GO:0045859 289 0.115
chaperone mediated protein folding GO:0061077 13 0.115
translation GO:0006412 132 0.115
Yeast
negative regulation of cellular protein metabolic process GO:0032269 353 0.114
protein targeting to er GO:0045047 7 0.114
Yeast
positive regulation of cellular amine metabolic process GO:0033240 7 0.113
regulation of nucleotide catabolic process GO:0030811 205 0.112
modification dependent macromolecule catabolic process GO:0043632 212 0.111
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.110
cytoplasmic transport GO:0016482 379 0.109
Yeast
cytoplasmic translation GO:0002181 8 0.106
Yeast
positive regulation of hydrolase activity GO:0051345 331 0.104
regulation of cellular ketone metabolic process GO:0010565 50 0.102
growth GO:0040007 202 0.101
de novo posttranslational protein folding GO:0051084 2 0.100
regulation of nucleotide metabolic process GO:0006140 269 0.100
negative regulation of mitotic cell cycle GO:0045930 102 0.100
Worm
regulation of cellular component biogenesis GO:0044087 281 0.100
myeloid cell differentiation GO:0030099 117 0.096
positive regulation of nucleotide catabolic process GO:0030813 185 0.096
protein targeting to membrane GO:0006612 42 0.095
Yeast
negative regulation of cell cycle GO:0045786 193 0.092
Worm
transmembrane transport GO:0055085 399 0.087
Yeast
protein maturation GO:0051604 233 0.087
regulation of atp metabolic process GO:1903578 29 0.084
neuron projection development GO:0031175 106 0.082
Fly
oxidation reduction process GO:0055114 396 0.082
regulation of cell growth GO:0001558 135 0.078
cell projection morphogenesis GO:0048858 129 0.077
Fly
regulation of mitotic cell cycle GO:0007346 189 0.075
Worm
positive regulation of protein phosphorylation GO:0001934 313 0.072
response to organonitrogen compound GO:0010243 156 0.072
aging GO:0007568 66 0.071
Worm
cellular component morphogenesis GO:0032989 314 0.071
Fly
cell part morphogenesis GO:0032990 137 0.070
Fly
positive regulation of cell death GO:0010942 263 0.069
regulation of purine nucleotide metabolic process GO:1900542 264 0.068
post embryonic development GO:0009791 2 0.065
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.062
protein targeting to nucleus GO:0044744 104 0.062
Yeast
receptor mediated endocytosis GO:0006898 84 0.062
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.061
neurogenesis GO:0022008 169 0.060
Fly
protein complex disassembly GO:0043241 52 0.059
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 284 0.059
generation of neurons GO:0048699 152 0.058
Fly
cellular macromolecular complex assembly GO:0034622 324 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
regulation of proteolysis GO:0030162 293 0.057
circadian sleep wake cycle process GO:0022410 2 0.055
cellular response to tumor necrosis factor GO:0071356 63 0.055
immune system development GO:0002520 195 0.054
positive regulation of nucleotide metabolic process GO:0045981 230 0.054
cellular lipid metabolic process GO:0044255 303 0.052
regulation of protein processing GO:0070613 150 0.051
cellular response to external stimulus GO:0071496 111 0.050
endocytosis GO:0006897 159 0.050
Worm
cellular amino acid metabolic process GO:0006520 116 0.050
translational initiation GO:0006413 48 0.049
immune response GO:0006955 307 0.049
amine metabolic process GO:0009308 44 0.049
regulation of endopeptidase activity GO:0052548 170 0.048
myeloid cell homeostasis GO:0002262 34 0.048
protein targeting to mitochondrion GO:0006626 19 0.047
Yeast
regulation of cytokine production GO:0001817 232 0.045
innate immune response GO:0045087 178 0.044
sleep GO:0030431 2 0.044
histone modification GO:0016570 251 0.044
cell type specific apoptotic process GO:0097285 125 0.043
endosomal transport GO:0016197 129 0.043
Worm
circadian sleep wake cycle GO:0042745 2 0.040
circadian sleep wake cycle sleep GO:0050802 2 0.039
cellular response to oxygen containing compound GO:1901701 276 0.037
neuron development GO:0048666 113 0.037
Fly
hematopoietic or lymphoid organ development GO:0048534 186 0.037
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
small gtpase mediated signal transduction GO:0007264 78 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
defense response GO:0006952 315 0.036
single organism carbohydrate metabolic process GO:0044723 193 0.036
negative regulation of catalytic activity GO:0043086 335 0.035
regulation of atpase activity GO:0043462 25 0.035
regulation of microtubule based process GO:0032886 74 0.035
cellular protein complex assembly GO:0043623 188 0.035
negative regulation of peptidase activity GO:0010466 91 0.035
cellular response to mechanical stimulus GO:0071260 39 0.034
cellular response to dna damage stimulus GO:0006974 379 0.034
cell recognition GO:0008037 9 0.034
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.034
Fly
covalent chromatin modification GO:0016569 254 0.034
negative regulation of protein phosphorylation GO:0001933 140 0.034
rna catabolic process GO:0006401 71 0.033
erythrocyte homeostasis GO:0034101 31 0.033
response to misfolded protein GO:0051788 5 0.033
positive regulation of apoptotic process GO:0043065 246 0.033
response to radiation GO:0009314 151 0.033
cellular response to abiotic stimulus GO:0071214 117 0.033
positive regulation of kinase activity GO:0033674 204 0.033
regulation of circadian sleep wake cycle GO:0042749 2 0.033
regulation of protein localization GO:0032880 296 0.032
response to mechanical stimulus GO:0009612 51 0.032
circadian behavior GO:0048512 2 0.032
cellular amine metabolic process GO:0044106 41 0.032
regulation of synaptic plasticity GO:0048167 3 0.032
lipid metabolic process GO:0006629 381 0.032
cellular ketone metabolic process GO:0042180 80 0.032
brain development GO:0007420 97 0.031
regulation of cell migration GO:0030334 289 0.031
chromatin organization GO:0006325 351 0.031
regulation of transferase activity GO:0051338 355 0.031
central nervous system development GO:0007417 123 0.030
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.030
multicellular organismal aging GO:0010259 3 0.030
Worm
cell cell signaling GO:0007267 155 0.030
Fly
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
mitotic cell cycle process GO:1903047 286 0.030
signal transduction by phosphorylation GO:0023014 297 0.030
homeostasis of number of cells GO:0048872 40 0.030
fatty acid metabolic process GO:0006631 115 0.029
cellular response to cytokine stimulus GO:0071345 181 0.028
negative regulation of protein kinase activity GO:0006469 98 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.027
positive regulation of proteolysis GO:0045862 142 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
system process GO:0003008 349 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
regulation of protein catabolic process GO:0042176 155 0.026
locomotory behavior GO:0007626 1 0.026
oocyte differentiation GO:0009994 2 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.026
regulation of cell motility GO:2000145 299 0.026
female gamete generation GO:0007292 2 0.026
carbohydrate metabolic process GO:0005975 207 0.026
spermatid differentiation GO:0048515 4 0.026
regeneration GO:0031099 4 0.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.025
response to organic cyclic compound GO:0014070 204 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.025
regulation of reactive oxygen species metabolic process GO:2000377 41 0.025
neuromuscular junction development GO:0007528 3 0.025
gtp catabolic process GO:0006184 237 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
neurotransmitter transport GO:0006836 10 0.024
Fly
microtubule based process GO:0007017 210 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
negative regulation of growth GO:0045926 97 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.024
cellular homeostasis GO:0019725 196 0.024
chemotaxis GO:0006935 157 0.024
Fly
single organism reproductive process GO:0044702 98 0.024
cell cycle phase transition GO:0044770 173 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
regulation of cellular component movement GO:0051270 334 0.023
meiosis i GO:0007127 4 0.023
regulation of protein stability GO:0031647 87 0.023
blastoderm segmentation GO:0007350 2 0.023
response to lipopolysaccharide GO:0032496 70 0.023
peptidyl serine phosphorylation GO:0018105 101 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
reproductive process GO:0022414 106 0.022
oogenesis GO:0048477 2 0.022
cellular response to hydrogen peroxide GO:0070301 37 0.022
cation transport GO:0006812 331 0.022
circulatory system development GO:0072359 262 0.022
intracellular protein transmembrane import GO:0044743 23 0.021
ribonucleoprotein complex subunit organization GO:0071826 81 0.021
Yeast
regulation of fibril organization GO:1902903 1 0.021
Human
regulation of protein transport GO:0051223 213 0.021
positive regulation of organelle organization GO:0010638 195 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
regulation of secretion by cell GO:1903530 177 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
segmentation GO:0035282 4 0.021
adult locomotory behavior GO:0008344 1 0.021
metal ion transport GO:0030001 272 0.020
response to metal ion GO:0010038 84 0.020
response to other organism GO:0051707 261 0.020
toxin transport GO:1901998 4 0.020
inner ear morphogenesis GO:0042472 4 0.020
associative learning GO:0008306 1 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
regulation of cellular response to stress GO:0080135 244 0.020
positive regulation of transferase activity GO:0051347 227 0.020
response to lipid GO:0033993 206 0.020
head development GO:0060322 108 0.020
embryonic placenta development GO:0001892 1 0.020
response to interferon gamma GO:0034341 39 0.020
protein acetylation GO:0006473 116 0.020
spermatid development GO:0007286 4 0.020
response to drug GO:0042493 81 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
response to molecule of bacterial origin GO:0002237 82 0.019
negative regulation of organelle organization GO:0010639 126 0.019
peptidyl serine modification GO:0018209 106 0.019
regulation of dna metabolic process GO:0051052 153 0.018
cellular carbohydrate metabolic process GO:0044262 84 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.018
sex determination GO:0007530 3 0.018
axon guidance GO:0007411 12 0.018
Fly
tissue regeneration GO:0042246 3 0.018
positive regulation of cell migration GO:0030335 172 0.018
peptidyl lysine modification GO:0018205 144 0.018
salivary gland morphogenesis GO:0007435 4 0.018
cell activation GO:0001775 213 0.018
oocyte development GO:0048599 1 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.018
Fly
wnt signaling pathway GO:0016055 156 0.018
positive regulation of atpase activity GO:0032781 19 0.018
neuron projection morphogenesis GO:0048812 50 0.017
Fly
maintenance of location GO:0051235 112 0.017
somitogenesis GO:0001756 2 0.017
blood vessel morphogenesis GO:0048514 162 0.017
alcohol metabolic process GO:0006066 114 0.017
tripartite regional subdivision GO:0007351 2 0.017
negative regulation of transport GO:0051051 176 0.017
response to lithium ion GO:0010226 2 0.017
regulation of kinase activity GO:0043549 314 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
protein stabilization GO:0050821 64 0.017
response to nutrient levels GO:0031667 81 0.017
interspecies interaction between organisms GO:0044419 156 0.017
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.017
regulation of locomotion GO:0040012 329 0.016
circulatory system process GO:0003013 113 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
regulation of atp catabolic process GO:1903289 25 0.016
sensory perception of pain GO:0019233 4 0.016
cellular response to oxidative stress GO:0034599 85 0.016
mapk cascade GO:0000165 288 0.016
sequestering of metal ion GO:0051238 24 0.016
neuroblast proliferation GO:0007405 4 0.016
neural tube formation GO:0001841 3 0.016
embryo development GO:0009790 123 0.016
Worm Fly
regulation of peptidase activity GO:0052547 180 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
cellular cation homeostasis GO:0030003 163 0.016
negative regulation of transferase activity GO:0051348 124 0.016
viral process GO:0016032 146 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
misfolded protein transport GO:0070843 1 0.016
axon cargo transport GO:0008088 2 0.016
multi organism cellular process GO:0044764 156 0.015
actin filament based process GO:0030029 224 0.015
regulation of multi organism process GO:0043900 157 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
phospholipid metabolic process GO:0006644 99 0.015
positive regulation of secretion GO:0051047 116 0.015
divalent inorganic cation transport GO:0072511 158 0.015
regulation of body fluid levels GO:0050878 99 0.015
mitochondrial membrane organization GO:0007006 40 0.015
axon development GO:0061564 34 0.015
Fly
histone acetylation GO:0016573 93 0.015
epithelial cell migration GO:0010631 119 0.015
lung alveolus development GO:0048286 4 0.015
regulation of mapk cascade GO:0043408 262 0.015
positive regulation of defense response GO:0031349 87 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
serotonin uptake GO:0051610 2 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.015
response to biotic stimulus GO:0009607 276 0.015
calcium ion transport GO:0006816 147 0.015
pituitary gland development GO:0021983 2 0.015
dephosphorylation GO:0016311 209 0.015
divalent metal ion transport GO:0070838 152 0.015
response to oxygen containing compound GO:1901700 369 0.015
regulation of postsynaptic membrane potential GO:0060078 1 0.015
gtp metabolic process GO:0046039 239 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
response to growth factor GO:0070848 205 0.015
leukocyte activation GO:0045321 164 0.014
endothelial cell migration GO:0043542 86 0.014
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.014
anion transport GO:0006820 161 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
cellular response to reactive oxygen species GO:0034614 50 0.014
anterior posterior axis specification GO:0009948 2 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.014
positive regulation of neural precursor cell proliferation GO:2000179 2 0.014
response to reactive oxygen species GO:0000302 61 0.014
protein processing GO:0016485 226 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
muscle system process GO:0003012 81 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
reproduction GO:0000003 63 0.014
Worm
lymphocyte activation GO:0046649 133 0.014
defense response to other organism GO:0098542 129 0.014
regulation of immune response GO:0050776 201 0.014
protein acylation GO:0043543 138 0.014
detection of stimulus GO:0051606 85 0.014
cell death in response to oxidative stress GO:0036473 29 0.014
ras protein signal transduction GO:0007265 73 0.014
cation homeostasis GO:0055080 189 0.014
regulation of defense response GO:0031347 154 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
response to extracellular stimulus GO:0009991 85 0.014
cardiovascular system development GO:0072358 262 0.014
response to fungus GO:0009620 4 0.014
nitrogen compound transport GO:0071705 191 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
organic anion transport GO:0015711 103 0.013
muscle cell fate commitment GO:0042693 4 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
positive regulation of transport GO:0051050 336 0.013
ameboidal type cell migration GO:0001667 135 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
neural crest cell development GO:0014032 3 0.013

HSPA1A disease predictions

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 68 0.178
cardiovascular system disease DOID:1287 106 0.178
muscular disease DOID:0080000 114 0.106
musculoskeletal system disease DOID:17 223 0.106
muscle tissue disease DOID:66 113 0.106
myopathy DOID:423 104 0.059
cardiomyopathy DOID:0050700 50 0.059
intrinsic cardiomyopathy DOID:0060036 50 0.059
dilated cardiomyopathy DOID:12930 32 0.031
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
neuromuscular disease DOID:440 38 0.022
neuropathy DOID:870 52 0.022
disease of cellular proliferation DOID:14566 174 0.021
cancer DOID:162 167 0.020
connective tissue disease DOID:65 109 0.016
disease of metabolism DOID:0014667 295 0.016
organ system cancer DOID:0050686 164 0.016
neurodegenerative disease DOID:1289 102 0.015
bone disease DOID:0080001 88 0.014
sensory system disease DOID:0050155 203 0.014
disease of mental health DOID:150 70 0.014