|
|
protein refolding
|
GO:0042026 |
14 |
1.000
|
|
|
|
de novo protein folding
|
GO:0006458 |
2 |
1.000
|
Mouse Rat |
|
|
chaperone cofactor dependent protein refolding
|
GO:0070389 |
4 |
1.000
|
|
|
|
protein folding
|
GO:0006457 |
38 |
1.000
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
1.000
|
Yeast |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
1.000
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.999
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.998
|
Human |
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.998
|
Human Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.997
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.996
|
Worm |
|
|
regulation of atp metabolic process
|
GO:1903578 |
29 |
0.996
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.995
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.994
|
Human |
|
|
protein transmembrane transport
|
GO:0071806 |
25 |
0.992
|
Yeast |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.991
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.991
|
Human |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.989
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.987
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.986
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.982
|
Human |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.971
|
|
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.971
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.964
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.957
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.953
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.952
|
Yeast |
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.942
|
Yeast Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.916
|
Human |
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.911
|
Human Yeast Worm |
|
|
chaperone mediated protein folding
|
GO:0061077 |
13 |
0.905
|
Mouse Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.901
|
Worm |
|
|
inclusion body assembly
|
GO:0070841 |
17 |
0.887
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.857
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.852
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.848
|
Worm |
|
|
growth
|
GO:0040007 |
202 |
0.843
|
Human Zebrafish |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.837
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.833
|
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
4 |
0.833
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.829
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.826
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.826
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.774
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.772
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.754
|
Yeast |
|
|
toxin transport
|
GO:1901998 |
4 |
0.736
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.719
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.715
|
|
|
|
protein targeting to mitochondrion
|
GO:0006626 |
19 |
0.705
|
Yeast |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.703
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.702
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.691
|
Yeast |
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.685
|
Yeast |
|
|
protein import into mitochondrial matrix
|
GO:0030150 |
1 |
0.683
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
19 |
0.682
|
|
|
|
regulation of atp catabolic process
|
GO:1903289 |
25 |
0.681
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.664
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.655
|
|
|
|
outer mitochondrial membrane organization
|
GO:0007008 |
4 |
0.652
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.633
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.624
|
Yeast Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.623
|
Yeast |
|
|
cell development
|
GO:0048468 |
328 |
0.604
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.604
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.595
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.594
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.586
|
Human |
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.580
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.575
|
Human Yeast Worm |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.574
|
Yeast |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.570
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.569
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.557
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.556
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.547
|
Yeast Mouse |
|
|
chaperone mediated protein complex assembly
|
GO:0051131 |
9 |
0.543
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.542
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.534
|
|
|
|
small nucleolar ribonucleoprotein complex assembly
|
GO:0000491 |
3 |
0.524
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.524
|
Worm |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.521
|
|
|
|
lung saccule development
|
GO:0060430 |
2 |
0.510
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.497
|
Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.495
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.481
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.473
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.472
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.469
|
Yeast Mouse Worm Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.453
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.452
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.437
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.428
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.426
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.425
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.414
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.410
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.403
|
|
|
|
establishment of protein localization to mitochondrial membrane
|
GO:0090151 |
7 |
0.392
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.391
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.385
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.382
|
Yeast |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.368
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.364
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.356
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.344
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.342
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.336
|
Yeast |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.334
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.331
|
Human Yeast Worm |
|
|
protein import into mitochondrial outer membrane
|
GO:0045040 |
4 |
0.330
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.319
|
Fly |
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.312
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.308
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.303
|
Human |
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.302
|
|
|
|
negative regulation of inclusion body assembly
|
GO:0090084 |
9 |
0.302
|
Human |
|
|
positive regulation of atp catabolic process
|
GO:1903291 |
19 |
0.299
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.298
|
|
|
|
sperm motility
|
GO:0030317 |
6 |
0.294
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.294
|
|
|
|
aging
|
GO:0007568 |
66 |
0.288
|
Worm |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.280
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.270
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.267
|
Worm Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.265
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.265
|
Yeast |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.260
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.259
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.259
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.256
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.252
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.246
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.241
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.241
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.237
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.235
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.232
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.226
|
Human Yeast |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.225
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.222
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.221
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.215
|
Worm |
|
|
embryo development
|
GO:0009790 |
123 |
0.213
|
Worm Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.213
|
Human |
|
|
sleep
|
GO:0030431 |
2 |
0.201
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.200
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.197
|
Yeast |
|
|
membrane organization
|
GO:0061024 |
292 |
0.196
|
Yeast |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.191
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.187
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.182
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.181
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.179
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.175
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.163
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.163
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.163
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.162
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.162
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.161
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.161
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.152
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.151
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.149
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.146
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.142
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.138
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.138
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.137
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.133
|
Fly |
|
|
regulation of transposition
|
GO:0010528 |
7 |
0.132
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.120
|
Fly |
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.118
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.117
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.112
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.110
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.110
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.109
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.107
|
Worm |
|
|
segmentation
|
GO:0035282 |
4 |
0.105
|
|
|
|
dna damage response detection of dna damage
|
GO:0042769 |
3 |
0.103
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.102
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.100
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.099
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.099
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.097
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.097
|
Human |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.096
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.096
|
Human |
|
|
rna interference
|
GO:0016246 |
4 |
0.092
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.090
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.089
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.088
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.087
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.086
|
Yeast |
|
|
spermatid development
|
GO:0007286 |
4 |
0.084
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.083
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.081
|
Mouse Worm |
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.081
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.081
|
|
|
|
response to type i interferon
|
GO:0034340 |
14 |
0.080
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.080
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.080
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.079
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.079
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.078
|
|
|
|
positive regulation of atp metabolic process
|
GO:1903580 |
20 |
0.077
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.077
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.075
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.074
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.073
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.073
|
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
3 |
0.072
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.072
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.071
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.071
|
Worm |
|
|
response to misfolded protein
|
GO:0051788 |
5 |
0.071
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.070
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.070
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.069
|
|
|
|
negative regulation of fibril organization
|
GO:1902904 |
1 |
0.068
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.068
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.068
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.068
|
|
|
|
cell cell recognition
|
GO:0009988 |
4 |
0.067
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.067
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.067
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.066
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.066
|
Yeast |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.066
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.065
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.065
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.064
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.064
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.061
|
Human |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.061
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.061
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.060
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.060
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.060
|
Human |
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.059
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.059
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.059
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.059
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.058
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.058
|
Yeast Mouse |
|
|
behavioral fear response
|
GO:0001662 |
0 |
0.058
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.057
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.056
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.055
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.055
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.054
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.054
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.054
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.054
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.054
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.053
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.051
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.050
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.049
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.049
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.049
|
|
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
20 |
0.048
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.048
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.048
|
Worm |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.047
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.047
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.046
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.046
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.046
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.046
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.046
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.046
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.044
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.044
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.043
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.043
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.043
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.042
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.042
|
Human |
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.042
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.042
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.041
|
|
|
|
system process
|
GO:0003008 |
349 |
0.041
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.041
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.041
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.040
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.040
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.040
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.040
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.040
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.039
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.039
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.039
|
Yeast |
|
|
cotranslational protein targeting to membrane
|
GO:0006613 |
2 |
0.038
|
Yeast |
|
|
fertilization
|
GO:0009566 |
12 |
0.038
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.038
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.038
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.036
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.036
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.035
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.035
|
Fly |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.034
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.034
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.034
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.034
|
|
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
3 |
0.034
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.033
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.033
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.033
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.032
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.032
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.032
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.031
|
|
|
|
cellular response to oxygen radical
|
GO:0071450 |
6 |
0.031
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.031
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.031
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.031
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.030
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.029
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.029
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.029
|
Human |
|
|
positive regulation of immune response to tumor cell
|
GO:0002839 |
8 |
0.029
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.028
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.028
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.028
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.027
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.027
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.026
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.026
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.025
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.025
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.025
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.025
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.025
|
Yeast |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.025
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.024
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.024
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.023
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.023
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.023
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.023
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.022
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.022
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.022
|
|
|
|
chaperone mediated protein folding requiring cofactor
|
GO:0051085 |
1 |
0.022
|
Mouse Rat |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.021
|
Yeast |
|
|
de novo posttranslational protein folding
|
GO:0051084 |
2 |
0.021
|
Mouse Rat |
|
|
positive regulation of glucocorticoid receptor signaling pathway
|
GO:2000324 |
1 |
0.021
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.021
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.021
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.021
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.021
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.020
|
Human |
|
|
viral life cycle
|
GO:0019058 |
132 |
0.020
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.020
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.020
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.020
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.020
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.020
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.019
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.019
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.019
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.019
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.019
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.019
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.019
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.019
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.019
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.019
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.018
|
Yeast |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.018
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.018
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.018
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.018
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.018
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.018
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.017
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.017
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.017
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.017
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.017
|
Yeast |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.017
|
Worm |
|
|
cognition
|
GO:0050890 |
43 |
0.017
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.017
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.017
|
|
|
|
peptidyl proline modification
|
GO:0018208 |
15 |
0.017
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.017
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.017
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.017
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.017
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.017
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.016
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.016
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.016
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.016
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.016
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.016
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.016
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.016
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.016
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.015
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.015
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.015
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.015
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.015
|
Yeast |
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.015
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.015
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.015
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.015
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.014
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.014
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.014
|
|
|
|
protein targeting to er
|
GO:0045047 |
7 |
0.014
|
Yeast |
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.014
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.014
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.014
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.014
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.014
|
Human |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.014
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.014
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.014
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.014
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.014
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.013
|
Human |
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.013
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.013
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.013
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.013
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.013
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.013
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.013
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.013
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.013
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.013
|
|
|
|
regulation of translational initiation in response to stress
|
GO:0043558 |
1 |
0.012
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.012
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.012
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.012
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.012
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.012
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.012
|
Human |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.012
|
Worm |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.012
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.012
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.012
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.012
|
|
|
|
regulation of viral genome replication
|
GO:0045069 |
48 |
0.012
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.012
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.012
|
Fly |
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.012
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.012
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.012
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.012
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.012
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.011
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.011
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.011
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.011
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.011
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.011
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.011
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.011
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.011
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.011
|
Fly |
|
|
viral process
|
GO:0016032 |
146 |
0.011
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.011
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.011
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.011
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.011
|
|
|
|
regulation of oxidative phosphorylation
|
GO:0002082 |
3 |
0.010
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.010
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.010
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.010
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.010
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.010
|
Yeast |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.010
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.010
|
|
